Research graph
References from Data-driven serum cytokine and chemokine phenotypes are associated with MRI-defined disc regression and persistent radicular pain in lumbar disc herniation. Local targets link to admitted publications; unresolved targets remain external evidence.
Clinical practice. Herniated lumbar intervertebral disk
10.1056/nejmcp1512658 · 2016 · External reference
Surgical vs nonoperative treatment for lumbar disk herniation: the Spine Patient Outcomes Research Trial (SPORT) observational cohort
10.1001/jama.296.20.2441 · 2006 · External reference
Surgical versus nonoperative treatment for lumbar disc herniation: eight-year results for the spine patient outcomes research trial
10.1097/brs.0000000000000088 · 2014 · External reference
What low back pain is and why we need to pay attention
10.1016/s0140-6736(18)30480-x · 2018 · External reference
Spontaneous regression of herniated nucleus pulposus
10.2214/ajr.145.2.371 · 1985 · External reference
The probability of spontaneous regression of lumbar herniated disc: a systematic review
10.1177/0269215514540919 · 2015 · External reference
Incidence of spontaneous resorption of lumbar disc herniation: a meta-analysis
2017 · External reference
The inflammatory response in the regression of lumbar disc herniation
10.1186/s13075-018-1743-4 · 2018 · External reference
Characteristics and mechanisms of resorption in lumbar disc herniation
10.1186/s13075-022-02894-8 · 2022 · External reference
Prevalence, clinical predictors, and mechanisms of resorption in lumbar disc herniation: a systematic review
10.52965/001c.121399 · 2024 · External reference
Contrast-enhanced magnetic resonance imaging in conservative management of lumbar disc herniation
10.1097/00007632-199801010-00015 · 1998 · External reference
Determinants of spontaneous resorption of intervertebral disc herniations
10.1097/01.brs.0000217681.83524.4a · 2006 · External reference
Role of cytokines in intervertebral disc degeneration: pain and disc content
10.1038/nrrheum.2013.160 · 2014 · External reference
Inflammation in intervertebral disc degeneration and regeneration
10.1098/rsif.2014.1191 · 2015 · External reference
Spontaneous production of monocyte chemoattractant protein-1 and interleukin-8 by the human lumbar intervertebral disc
10.1097/00007632-200207010-00006 · 2002 · External reference
Intervertebral disc cells produce tumor necrosis factor alpha, interleukin-1beta, and monocyte chemoattractant protein-1 immediately after herniation: an experimental study using a new hernia model
10.1097/01.brs.0000149194.17891.bf · 2005 · External reference
Matrix metalloproteinase-3-dependent generation of a macrophage chemoattractant in a model of herniated disc resorption
10.1172/jci7090 · 2000 · External reference
Influence of macrophage infiltration of herniated disc tissue on the production of matrix metalloproteinases leading to disc resorption
10.1097/00007632-200107150-00004 · 2001 · External reference
Serum levels of the pro-inflammatory interleukins 6 (IL-6) and -8 (IL-8) in patients with lumbar radicular pain due to disc herniation: a 12-month prospective study
10.1016/j.bbi.2015.01.008 · 2015 · External reference
Inflammatory serum protein profiling of patients with lumbar radicular pain one year after disc herniation
10.1155/2016/3874964 · 2016 · External reference
Serum levels of the proinflammatory cytokine interleukin-6 vary based on diagnoses in individuals with lumbar intervertebral disc diseases
10.1186/s13075-015-0887-8 · 2016 · External reference
The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies
10.1136/bmj.39335.541782.ad · 2007 · External reference
Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): the TRIPOD statement
10.1186/s12916-014-0241-z · 2015 · External reference
mclust 5: Clustering, classification and density estimation using Gaussian finite mixture models
10.32614/rj-2016-021 · 2016 · External reference
A modified poisson regression approach to prospective studies with binary data
10.1093/aje/kwh090 · 2004 · External reference
Systematic review and meta-analysis of predictive factors for spontaneous regression in lumbar disc herniation
10.3171/2023.6.spine23367 · 2023 · External reference
Chemokines and leukocyte traffic
10.1038/33340 · 1998 · External reference
A guide to chemokines and their receptors
10.1111/febs.14466 · 2018 · External reference
Immune microenvironment in intervertebral disc degeneration: pathophysiology and therapeutic potential
10.3389/fimmu.2025.1563635 · 2025 · External reference
Role of macrophage in intervertebral disc degeneration
10.1038/s41413-024-00397-7 · 2025 · External reference
Interleukin-6: an emerging regulator of pathological pain
10.1186/s12974-016-0607-6 · 2016 · External reference
Neuroinflammation and central sensitization in chronic and widespread pain
10.1097/aln.0000000000002130 · 2018 · External reference
Inflammation preservation strategy: reconciling pain control and disc resorption in lumbar disc herniation
10.3389/fimmu.2025.1653681 · 2025 · External reference
