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References from Unraveling tumor cell heterogeneity and epithelial-mesenchymal plasticity in gastric adenocarcinoma: an integrative multi-omics framework evaluating PVR/CD155 as a tumor cell-intrinsic EMT-associated target. Local targets link to admitted publications; unresolved targets remain external evidence.
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
10.3322/caac.21834 · 2024 · External reference
Gastric cancer
10.1016/b978-0-443-15609-0.00017-9 · 2020 · External reference
Gastric cancer treatment: recent progress and future perspectives
10.1186/s13045-023-01451-3 · 2023 · External reference
Single-cell atlas of lineage states, tumor microenvironment, and subtype-specific expression programs in gastric cancer
10.1158/2159-8290.cd-21-0683 · 2022 · External reference
Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma
10.1038/s41591-020-1125-8 · 2021 · External reference
EMT: 2016
10.1016/j.cell.2016.06.028 · 2016 · External reference
New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer
10.1038/s41580-018-0080-4 · 2019 · External reference
Alternative splicing in EMT and TGF-β signaling during cancer progression
10.1016/j.semcancer.2024.04.001 · 2024 · External reference
POSTN(+) cancer-associated fibroblasts determine the efficacy of immunotherapy in hepatocellular carcinoma
10.1136/jitc-2023-008721 · 2024 · External reference
Enhanced epithelial-mesenchymal transition signatures are linked with adverse tumor microenvironment, angiogenesis and worse survival in gastric cancer
10.1038/s41417-024-00756-w · 2024 · External reference
Single-cell RNA sequencing to map tumor heterogeneity in gastric carcinogenesis paving roads to individualized therapy
10.1007/s00262-024-03820-4 · 2024 · External reference
Exploring tissue architecture using spatial transcriptomics
10.1038/s41586-021-03634-9 · 2021 · External reference
Cell2location maps fine-grained cell types in spatial transcriptomics
10.1038/s41587-021-01139-4 · 2022 · External reference
A guide to machine learning for biologists
10.1038/s41580-021-00407-0 · 2022 · External reference
DoubletFinder: Doublet detection in single-cell RNA sequencing data using artificial nearest neighbors
10.1016/j.cels.2019.03.003 · 2019 · External reference
Fast, sensitive and accurate integration of single-cell data with Harmony
10.1038/s41592-019-0619-0 · 2019 · External reference
scTour: a deep learning architecture for robust inference and accurate prediction of cellular dynamics
10.1186/s13059-023-02988-9 · 2023 · External reference
SpaTopic: A statistical learning framework for exploring tumor spatial architecture from spatially resolved transcriptomic data
10.1126/sciadv.adp4942 · 2024 · External reference
NicheNet: modeling intercellular communication by linking ligands to target genes
10.1038/s41592-019-0667-5 · 2020 · External reference
CellProfiler 4: improvements in speed, utility and usability
10.1186/s12859-021-04344-9 · 2021 · External reference
Mime: A flexible machine-learning framework to construct and visualize models for clinical characteristics prediction and feature selection
10.1016/j.csbj.2024.06.035 · 2024 · External reference
AutoDock Vina 1.2.0: New docking methods, expanded force field, and Python bindings
10.1021/acs.jcim.1c00203 · 2021 · External reference
AutoDockFR: Advances in protein-ligand docking with explicitly specified binding site flexibility
10.1371/journal.pcbi.1004586 · 2015 · External reference
Development and testing of a general amber force field
10.1002/jcc.20035 · 2004 · External reference
Langevin stabilization of molecular-dynamics simulations of polymers by means of quasisymplectic algorithms
10.1063/1.2464095 · 2007 · External reference
Improved generalized Born solvent model parameters for protein simulations
10.1021/ct3010485 · 2013 · External reference
Overexpression of a secretory leukocyte protease inhibitor in human gastric cancer
10.1002/ijc.23746 · 2008 · External reference
Targeting secretory leukocyte protease inhibitor (SLPI) inhibits colorectal cancer cell growth, migration and invasion via downregulation of AKT
10.7717/peerj.9400 · 2020 · External reference
Secretory leukocyte protease inhibitor (SLPI) in mucosal tissues: Protects against inflammation, but promotes cancer
10.1016/j.cytogfr.2021.01.005 · 2021 · External reference
Expression of the immune modulator secretory leukocyte protease inhibitor (SLPI) in colorectal cancer liver metastases and matched primary tumors is associated with a poorer prognosis
10.1080/2162402x.2020.1832761 · 2020 · External reference
Prognostic and clinicopathological significance of CD155 expression in cancer patients: a meta-analysis
10.1186/s12957-022-02813-w · 2022 · External reference
The immunoreceptor TIGIT regulates antitumor and antiviral CD8(+) T cell effector function
10.1016/j.ccell.2014.10.018 · 2014 · External reference
Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8(+) T cell responses
10.1016/j.immuni.2022.02.005 · 2022 · External reference