Research graph
References from IL-5/IL-5R blockade enables safe non-steroidal anti-inflammatory agent reintroduction in non-steroidal anti-inflammatory exacerbated respiratory disease. Local targets link to admitted publications; unresolved targets remain external evidence.
Diagnosis and management of NSAID-exacerbated respiratory disease (N-ERD)-a EAACI position paper
10.1111/all.13599 · 2019 · External reference
Systematic review of prevalence of aspirin induced asthma and its implications for clinical practice
10.1136/bmj.328.7437.434 · 2004 · External reference
Respiratory hypersensitivity reactions to NSAIDs in Europe: the global allergy and asthma network (GA(2) LEN) survey
10.1111/all.12941 · 2016 · External reference
NSAIDs-hypersensitivity often induces a blended reaction pattern involving multiple organs
10.1038/s41598-018-34668-1 · 2018 · External reference
Evaluation of hypersensitivity reactions to nonsteroidal anti-inflammatory drugs according to the latest classification
10.1111/all.12689 · 2015 · External reference
Updating the classification and routine diagnosis of NSAID hypersensitivity reactions: A WAO statement
10.1016/j.waojou.2025.101086 · 2025 · External reference
Aeroallergen sensitization influences quality of life and comorbidities in patients with nasal polyposis
10.2500/ajra.2012.26.3792 · 2012 · External reference
Aspirin intolerance and allergy to house dust mites: important factors associated with development of severe asthma
10.1016/s1081-1206(10)61782-6 · 2004 · External reference
Emerging biomarkers beyond leukotrienes for the management of nonsteroidal anti-inflammatory drug (NSAID)-exacerbated respiratory disease
10.4168/aair.2022.14.2.153 · 2022 · External reference
Complementary participation of genetics and epigenetics in development of NSAID-exacerbated respiratory disease
10.4168/aair.2019.11.6.779 · 2019 · External reference
Blood eosinophil count is a useful biomarker to identify patients with severe eosinophilic asthma
10.1513/annalsats.201310-354oc · 2014 · External reference
The eosinophil and airway remodelling in asthma
10.1111/j.1752-699x.2010.00192.x · 2010 · External reference
Eosinophil-derived cationic proteins activate the synthesis of remodeling factors by airway epithelial cells
10.4049/jimmunol.177.7.4861 · 2006 · External reference
Efficacy and safety of treatment with biologicals (benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab) for severe eosinophilic asthma. A systematic review for the EAACI guidelines - recommendations on the use of biologicals in severe asthma
10.1111/all.14221 · 2020 · External reference
Inflammatory and homeostatic roles of eosinophil subpopulations in chronic rhinosinusitis with nasal polyp pathogenesis
10.3389/fimmu.2025.1568541 · 2025 · External reference
Real-world outcomes on quality-of-life improvement in patients with nasal polyposis treated with mepolizumab. RINOSUR study
10.1016/j.otoeng.2024.08.001 · 2025 · External reference
Efficacy and safety of benralizumab in chronic rhinosinusitis with nasal polyps: A randomized, placebo-controlled trial
10.1016/j.jaci.2021.08.030 · 2022 · External reference
Aspirin desensitization achieved after omalizumab treatment in a patient with aspirin-exacerbated urticaria and respiratory disease
2015 · External reference
Aspirin tolerance in patients with nonsteroidal anti-inflammatory drug-exacerbated respiratory disease following treatment with omalizumab
10.1016/j.jaip.2016.12.013 · 2017 · External reference
Nonsteroidal anti-inflammatory drug (NSAID) tolerance after biological therapy in patients with NSAID-exacerbated respiratory disease: A randomized comparative trial
10.1016/j.jaip.2023.04.033 · 2023 · External reference
Dupilumab increases aspirin tolerance in NSAID-exacerbated respiratory disease
10.1183/13993003.01335-2022 · 2023 · External reference
Global initiative for asthma guidelines 2024: An update
10.1007/s13312-024-3260-7 · 2024 · External reference
EAACI/GA2LEN guideline: aspirin provocation tests for diagnosis of aspirin hypersensitivity
10.1111/j.1398-9995.2007.01409.x · 2007 · External reference
NSAID-exacerbated respiratory disease (NERD): From pathogenesis to improved care
10.3389/fphar.2020.01147 · 2020 · External reference
Improvements in an oral aspirin challenge protocol for the diagnosis of aspirin hypersensitivity
10.1111/j.1365-2222.2005.02261.x · 2005 · External reference
Classification of reactions to nonsteroidal antiinflammatory drugs
10.1016/j.iac.2012.10.008 · 2013 · External reference
VAS--visual analog scale
10.4045/tidsskr.13.1145 · 2014 · External reference
Psychometric validity of the 22-item sinonasal outcome test
10.1111/j.1749-4486.2009.01995.x · 2009 · External reference
Development of the asthma control test: a survey for assessing asthma control
10.1016/j.jaci.2003.09.008 · 2004 · External reference
Key recommendations for primary care from the 2022 global initiative for asthma (GINA) update
10.1038/s41533-023-00330-1 · 2023 · External reference
Mepolizumab targets multiple immune cells in aspirin-exacerbated respiratory disease
10.1016/j.jaci.2021.05.043 · 2021 · External reference
Non-steroidal anti-inflammatory drug hypersensitivity in adults and the factors associated with asthma
10.1016/j.rmed.2013.03.014 · 2013 · External reference
Chronic urticaria: unmet needs, emerging drugs, and new perspectives on personalised treatment
10.1016/s0140-6736(24)00852-3 · 2024 · External reference
Biologics in severe asthma: a state-of-the-art review
10.1183/16000617.0088-2024 · 2025 · External reference
Efficacy and safety of biologics for chronic rhinosinusitis with nasal polyps: a meta-analysis of real-world evidence
10.1111/all.16499 · 2025 · External reference
Pharmacokinetics/pharmacodynamics of benralizumab in chronic rhinosinusitis with nasal polyps: Phase III, randomized, placebo-controlled OSTRO trial
10.1111/bcp.16087 · 2024 · External reference
Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNAPSE): a randomised, double-blind, placebo-controlled, phase 3 trial
10.1016/s2213-2600(21)00097-7 · 2021 · External reference
Prevalence of aspirin-exacerbated respiratory disease among asthmatic patients: a meta-analysis of the literature
10.1016/j.jaci.2014.08.020 · 2015 · External reference