Research graph
References from Intravitreal exposure to the SARS-CoV-2 spike protein is associated with aggravated retinal lesions in a murine model of central retinal vein occlusion. Local targets link to admitted publications; unresolved targets remain external evidence.
Global epidemiology of retinal vein occlusion: a systematic review and meta-analysis of prevalence, incidence, and risk factors
10.7189/jogh.09.010427 · 2019 · External reference
The development of risk factors and cytokines in retinal vein occlusion
10.3389/fmed.2022.910600 · 2022 · External reference
Retinal vein occlusion: beyond the acute event
10.1016/j.survophthal.2010.11.006 · 2011 · External reference
Update on retinal vein occlusion
10.1097/apo.0000000000000598 · 2023 · External reference
COVID-19 and thrombosis: from bench to bedside
10.1016/j.tcm.2020.12.004 · 2021 · External reference
Pulmonary embolism and deep vein thrombosis in COVID-19: a systematic review and meta-analysis
10.1148/radiol.2020203557 · 2021 · External reference
Risks of deep vein thrombosis, pulmonary embolism, and bleeding after COVID-19: nationwide self-controlled cases series and matched cohort study
10.1136/bmj-2021-069590 · 2022 · External reference
Deep vein thrombosis and pulmonary thrombosis after BNT162b2 mRNA SARS-CoV2 vaccination
10.1253/circj.cj-21-1055 · 2022 · External reference
Consecutive central and branch retinal vein occlusions in the same eye of a young healthy COVID-19 patient: a unique case report
10.1016/j.ajoc.2022.101669 · 2022 · External reference
Hemi- and central retinal vein occlusion associated with COVID-19 infection in young patients without known risk factors
10.1016/j.oret.2022.02.004 · 2022 · External reference
Bilateral central retinal vein occlusion in a 40-year-old man with severe coronavirus disease 2019 (COVID-19) pneumonia
10.12659/ajcr.927691 · 2020 · External reference
Impending central retinal vein occlusion in a patient with coronavirus disease 2019 (COVID-19)
10.1080/09273948.2020.1807023 · 2020 · External reference
Ocular occlusions in two cases of COVID-19
10.4103/ijo.ijo_3139_21 · 2022 · External reference
Post-Coronavirus disease 2019 (COVID-19) syndrome associated with central retinal vein occlusion: a case report
10.1080/09273948.2021.1977830 · 2023 · External reference
Evidence of SARS-CoV-2 transmission through the ocular route
10.2147/opth.s295283 · 2021 · External reference
Assessing viral shedding and infectivity of tears in coronavirus disease 2019 (COVID-19) patients
10.1016/j.ophtha.2020.03.026 · 2020 · External reference
Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection
10.1002/jmv.25725 · 2020 · External reference
The evidence of SARS-CoV-2 infection on ocular surface
10.1016/j.jtos.2020.03.010 · 2020 · External reference
ACE2 And TMPRSS2 are expressed on the human ocular surface, suggesting susceptibility to SARS-CoV-2 infection
10.1016/j.jtos.2020.06.007 · 2020 · External reference
Co-expression of the SARS-CoV-2 entry receptors ACE2 and TMPRSS2 in healthy human conjunctiva
10.1016/j.exer.2021.108527 · 2021 · External reference
Ocular surface expression of SARS-CoV-2 receptors
10.1080/09273948.2020.1772314 · 2020 · External reference
Presumed SARS-CoV-2 viral particles in the human retina of patients with COVID-19
10.1001/jamaophthalmol.2021.2795 · 2021 · External reference
SARS-CoV-2 infects cells lining the blood-retinal barrier and induces a hyperinflammatory immune response in the retina via systemic exposure
10.1371/journal.ppat.1012156 · 2024 · External reference
Ocular tropism of SARS-CoV-2 in animal models with retinal inflammation via neuronal invasion following intranasal inoculation
10.1038/s41467-022-35225-1 · 2022 · External reference
Detection of SARS-CoV-2-RNA in post-mortem samples of human eyes
10.1007/s00417-021-05529-x · 2022 · External reference
Single-cell RNA sequencing: a new opportunity for retinal research
10.1002/wrna.1652 · 2021 · External reference
Development of a behavior change intervention to improve physical activity in patients with COPD using the behavior change wheel: a non-randomized trial
10.1038/s41598-023-50099-z · 2023 · External reference
Α-Melanocyte-stimulating hormone protects early diabetic retina from blood-retinal barrier breakdown and vascular leakage via MC4R
10.1159/000487029 · 2018 · External reference
Proteomic analysis of retinas in a rat model of high-fat diet-induced type 2 diabetes: implications of interventional targets for nonproliferative diabetic retinopathy
10.2147/dddt.s501318 · 2025 · External reference
Mouse-adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge
10.1371/journal.pbio.3001284 · 2021 · External reference
The basic reproductive number and particle-to-plaque ratio: comparison of these two parameters of viral infectivity
10.1186/s12985-021-01566-4 · 2021 · External reference
The total number and mass of SARS-CoV-2 virions
10.1073/pnas.2024815118 · 2021 · External reference
Virion morphology and on-virus spike protein structures of diverse SARS-CoV-2 variants
10.1038/s44318-024-00303-1 · 2024 · External reference
Pathophysiological role of VEGF on retinal edema and nonperfused areas in mouse eyes with retinal vein occlusion
10.1167/iovs.18-23994 · 2018 · External reference
Exploring laser-induced acute and chronic retinal vein occlusion mouse models: development, temporal in vivo imaging, and application perspectives
10.1371/journal.pone.0305741 · 2024 · External reference
Lack of netrin-4 alters vascular remodeling in the retina
10.1007/s00417-019-04447-3 · 2019 · External reference
Nanosecond laser treatment for age-related macular degeneration does not induce focal vision loss or new vessel growth in the retina
10.1167/iovs.17-23098 · 2018 · External reference
SARS-CoV-2 spike S1 protein induces microglial NLRP3-dependent neuroinflammation and cognitive impairment in mice
10.1016/j.expneurol.2024.115020 · 2025 · External reference
Recombinant SARS-CoV-2 spike protein and its receptor binding domain stimulate release of different pro-inflammatory mediators via activation of distinct receptors on human microglia cells
10.1007/s12035-023-03493-7 · 2023 · External reference
SARS-CoV-2 spike S1 subunit induces neuroinflammatory, microglial and behavioral sickness responses: evidence of PAMP-like properties
10.1016/j.bbi.2021.12.007 · 2022 · External reference
Midkine is neuroprotective and influences glial reactivity and the formation of Müller glia-derived progenitor cells in chick and mouse retinas
10.1002/glia.23976 · 2021 · External reference
Spatial organization of the mouse retina at single cell resolution by MERFISH
10.1038/s41467-023-40674-3 · 2023 · External reference
The human Müller cell line MIO-M1 expresses opsins
2011 · External reference
In vitro characterization of a spontaneously immortalized human Müller cell line (MIO-M1)
2002 · External reference
Different responses of the MIO-M1 Mueller cell line to angiotensin II under hyperglycemic or hypoxic conditions
10.3892/br.2023.1644 · 2023 · External reference
Laboratory evaluation of hypercoagulable states in patients with central retinal vein occlusion who are less than 56 years of age
10.1016/s0161-6420(01)00842-9 · 2002 · External reference
Clinical features of central retinal vein occlusion in young patients
10.1007/s40123-022-00534-7 · 2022 · External reference
Comparison of cytokine levels from undiluted vitreous of untreated patients with retinal vein occlusion
10.1111/j.1755-3768.2011.02292.x · 2012 · External reference
Investigation of retinal morphology alterations using spectral domain optical coherence tomography in a mouse model of retinal branch and central retinal vein occlusion
10.1371/journal.pone.0119046 · 2015 · External reference
Development of a novel model of central retinal vascular occlusion and the therapeutic potential of the adrenomedullin-receptor activity-modifying protein 2 system
10.1016/j.ajpath.2018.10.021 · 2019 · External reference
SARS-CoV-2 omicron virus causes attenuated disease in mice and hamsters
10.1038/s41586-022-04441-6 · 2022 · External reference
Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 omicron
10.1038/s41586-022-04442-5 · 2022 · External reference
Broadly neutralizing antibodies overcome SARS-CoV-2 omicron antigenic shift
10.1038/s41586-021-04386-2 · 2022 · External reference
Emerging SARS-CoV-2 variants expand species tropism to murines
10.1016/j.ebiom.2021.103643 · 2021 · External reference
SARS-CoV-2 isolation from ocular secretions of a patient with COVID-19 in Italy with prolonged viral RNA detection
10.7326/m20-1176 · 2020 · External reference
S100a8/A9 in inflammation
10.3389/fimmu.2018.01298 · 2018 · External reference
Mo-derived perivascular macrophage recruitment protects against endothelial cell death in retinal vein occlusion
10.1186/s12974-019-1547-8 · 2019 · External reference
Serglycin: at the crossroad of inflammation and malignancy
10.3389/fonc.2013.00327 · 2014 · External reference
Pediatric T-lymphoblastic leukemia with an entirely mature immunophenotype: a prompt and challenging diagnosis
10.1097/mph.0000000000002967 · 2025 · External reference
Analysis of antigen expression in T-cell acute lymphoblastic leukemia by Multicolor flow cytometry: implications for the detection of measurable residual disease
10.3390/ijms26052002 · 2025 · External reference
The expression and prognostic impact of immune cytolytic activity-related markers in human malignancies: a comprehensive meta-analysis
10.3389/fonc.2018.00027 · 2018 · External reference
Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium
10.1038/s41467-024-49186-0 · 2024 · External reference
SELL marks an effector-deficient CD8(+) T cell subset that promotes intracerebral hemorrhage and responds to rutin therapy
10.1155/humu/4033506 · 2026 · External reference
Long noncoding RNA AW112010 promotes the differentiation of inflammatory T cells by suppressing IL-10 expression through histone demethylation
10.4049/jimmunol.2000330 · 2020 · External reference
Expression of the SARS-CoV-2 receptor ACE2 in human retina and diabetes-implications for retinopathy
10.1167/iovs.62.7.6 · 2021 · External reference
A perspective on the Müller cell-neuron metabolic partnership in the inner retina
10.1007/s12035-017-0760-7 · 2018 · External reference
New functions of Müller cells
10.1002/glia.22477 · 2013 · External reference
Fluoride exposure affects glutamine uptake in Müller glia cells
10.1007/s12640-020-00263-4 · 2020 · External reference
Large-scale multi-omic analysis of COVID-19 severity
10.1016/j.cels.2020.10.003 · 2021 · External reference
A role for lengsin, a recruited enzyme, in terminal differentiation in the vertebrate lens
10.1074/jbc.m709144200 · 2008 · External reference
Structural and functional properties of lengsin, a pseudo-glutamine synthetase in the transparent human lens
10.1016/j.bbrc.2006.09.062 · 2006 · External reference
Lengsin is a survivor of an ancient family of class I glutamine synthetases re-engineered by evolution for a role in the vertebrate lens
10.1016/j.str.2006.10.008 · 2006 · External reference
Targeting LGSN restores sensitivity to chemotherapy in gastric cancer stem cells by triggering pyroptosis
10.1038/s41419-023-06081-8 · 2023 · External reference
Stratification of hypertension and SARS-CoV-2 infection by quantitative NMR spectroscopy of human blood serum
10.1038/s43856-023-00365-y · 2023 · External reference
Disturbed lipid and amino acid metabolisms in COVID-19 patients
10.1007/s00109-022-02177-4 · 2022 · External reference
Lipidomic and metabolomic changes in community-acquired and COVID-19 pneumonia
10.1016/j.jlr.2024.100622 · 2024 · External reference
Dietary supplement enriched in antioxidants and omega-3 promotes glutamine synthesis in Müller cells: a key process against oxidative stress in retina
10.3390/nu13093216 · 2021 · External reference
Transcriptomic analysis revealed increased expression of genes involved in keratinization in the tears of COVID-19 patients
10.1038/s41598-021-99344-3 · 2021 · External reference
