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References from Whole-genome characterization of seven multidrug-resistant Neisseria gonorrhoeae isolates from a single tertiary center in Beijing. Local targets link to admitted publications; unresolved targets remain external evidence.
Ceftriaxone resistance in Neisseria gonorrhoeae associated with the penA-60.001 allele in Hanoi, Viet Nam
10.1016/s1473-3099(24)00230-5 · 2024 · External reference
BLAST+: architecture and applications
10.1186/1471-2105-10-421 · 2009 · External reference
Emergence of extensively drug-resistant Neisseria gonorrhoeae, France, 2023
10.3201/eid3009.240557 · 2024 · External reference
In silico detection and typing of plasmids using PlasmidFinder and plasmid multilocus sequence typing
10.1128/aac.02412-14 · 2014 · External reference
Could dampening expression of the Neisseria gonorrhoeae mtrCDE-encoded efflux pump be a strategy to preserve currently or resurrect formerly used antibiotics to treat gonorrhea?
10.1128/mbio.01576-19 · 2019 · External reference
Identification of internationally disseminated ceftriaxone-resistant Neisseria gonorrhoeae strain FC428, China
10.3201/eid2507.190172 · 2019 · External reference
Unresolved reference
2026 · External reference
Target-mediated fluoroquinolone resistance in Neisseria gonorrhoeae: actions of ciprofloxacin against gyrase and topoisomerase IV
10.1021/acsinfecdis.4c00041 · 2024 · External reference
Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins
10.1093/nar/gku1196 · 2015 · External reference
progressiveMauve: multiple genome alignment with gene gain, loss and rearrangement
10.1371/journal.pone.0011147 · 2010 · External reference
In silico gepotidacin target mining among 33213 global Neisseria gonorrhoeae genomes from 1928 to 2023 combined with gepotidacin MIC testing of 22 gonococcal isolates with different GyrA and ParC substitutions
10.1093/jac/dkae217 · 2024 · External reference
A gonococcal porA pseudogene: implications for understanding the evolution and pathogenicity of Neisseria gonorrhoeae
10.1046/j.1365-2958.1998.01101.x · 1998 · External reference
Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, august 2018
10.2807/1560-7917.es.2018.23.47.1800617 · 2018 · External reference
A fast real-time polymerase chain reaction method for sensitive and specific detection of the Neisseria gonorrhoeae porA pseudogene
10.2353/jmoldx.2006.060024 · 2006 · External reference
High-level chromosomally mediated tetracycline resistance in Neisseria gonorrhoeae results from a point mutation in the rpsJ gene encoding ribosomal protein S10 in combination with the mtrR and penB resistance determinants
10.1128/aac.49.10.4327-4334.2005 · 2005 · External reference
MAFFT multiple sequence alignment software version 7: improvements in performance and usability
10.1093/molbev/mst010 · 2013 · External reference
Rationale for a Neisseria gonorrhoeae susceptible-only interpretive breakpoint for azithromycin
10.1093/cid/ciz292 · 2020 · External reference
Clonal expansion and spread of the ceftriaxone-resistant Neisseria gonorrhoeae strain FC428, identified in Japan in 2015, and closely related isolates
10.1093/jac/dkz129 · 2019 · External reference
High prevalence and emerging cephalosporin resistance of penicillinase-producing Neisseria gonorrhoeae in Meizhou, China (2022-2024)
10.1186/s12879-025-12030-x · 2025 · External reference
Dissemination and genome analysis of high-level ceftriaxone-resistant penA 60.001 Neisseria gonorrhoeae strains from the Guangdong gonococcal antibiotics susceptibility Programme (GD-GASP), 2016-2019
10.1080/22221751.2021.2011618 · 2016 · External reference
Neisseria gonorrhoeae isolates with reduced susceptibility to cefixime and ceftriaxone: association with genetic polymorphisms in penA, mtrR, porB1b, and ponA
10.1128/aac.01604-06 · 2007 · External reference
Differential contribution of PBP occupancy and efflux on the effectiveness of β-lactams at their target site in clinical isolates of Neisseria gonorrhoeae
10.1371/journal.ppat.1012783 · 2024 · External reference
Cryo-EM structures of a gonococcal multidrug efflux pump illuminate a mechanism of drug recognition and resistance
10.1128/mbio.00996-20 · 2020 · External reference
Increased power from conditional bacterial genome-wide association identifies macrolide resistance mutations in Neisseria gonorrhoeae
10.1038/s41467-020-19250-6 · External reference
Efflux pump antibiotic binding site mutations are associated with azithromycin nonsusceptibility in clinical Neisseria gonorrhoeae isolates
10.1128/mbio.01509-20 · External reference
Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance
10.1111/j.1469-0691.2011.03570.x · 2012 · External reference
Evidence of horizontal gene transfer of 50S ribosomal genes rplB, rplD, and rplY in Neisseria gonorrhoeae
10.3389/fmicb.2021.683901 · 2021 · External reference
Impact of mutations in the mtrR, rpdlVD and rrl genes on azithromycin resistance in Neisseria gonorrhoeae
10.1371/journal.pone.0306695 · 2024 · External reference
IQ-TREE 2: new models and efficient methods for phylogenetic inference in the genomic era
10.1093/molbev/msaa015 · 2020 · External reference
Molecular mechanisms of drug resistance and epidemiology of multidrug-resistant variants of Neisseria gonorrhoeae
10.3390/ijms231810499 · 2022 · External reference
New ceftriaxone- and multidrug-resistant Neisseria gonorrhoeae strain with a novel mosaic penA gene isolated in Japan
10.1128/aac.00504-16 · 2016 · External reference
A whole-genome sequencing analysis of Neisseria gonorrhoeae isolates in China: an observational study
10.1016/j.eclinm.2019.01.010 · 2019 · External reference
Emerging epidemic of the Africa-type plasmid in penicillinase-producing Neisseria gonorrhoeae in Guangdong, China, 2013-2022
10.1080/22221751.2024.2440489 · 2025 · External reference
In vitro selection of Neisseria gonorrhoeae unveils novel mutations associated with extended-spectrum cephalosporin resistance
10.3389/fcimb.2022.924764 · 2022 · External reference
Bakta: rapid and standardized annotation of bacterial genomes via alignment-free sequence identification
10.1099/mgen.0.000685 · 2021 · External reference
Antibiotic resistance in Neisseria gonorrhoeae: challenges in research and treatment
10.3390/microorganisms10091699 · 2022 · External reference
Unresolved reference
2026 · External reference
The porA pseudogene of Neisseria gonorrhoeae--low level of genetic polymorphism and a few, mainly identical, inactivating mutations
10.1111/j.1600-0463.2005.apm_206.x · 2005 · External reference
Limitations of global surveillance for Neisseria gonorrhoeae antimicrobial resistance
10.3201/eid3206.260378 · 2026 · External reference
In vivo-selected compensatory mutations restore the fitness cost of mosaic penA alleles that confer ceftriaxone resistance in Neisseria gonorrhoeae
10.1128/mbio.01905-17 · 2018 · External reference
Genomic epidemiology of Neisseria gonorrhoeae in Shenzhen, China, during 2019-2020: increased spread of ceftriaxone-resistant isolates brings insights for strengthening public health responses
10.1128/spectrum.01728-23 · 2023 · External reference
16S ribosomal DNA amplification for phylogenetic study
10.1128/jb.173.2.697-703.1991 · 1991 · External reference
Antimicrobial resistance in Neisseria gonorrhoeae: global surveillance and a call for international collaborative action
10.1371/journal.pmed.1002344 · 2017 · External reference
Unicycler: resolving bacterial genome assemblies from short and long sequencing reads
10.1371/journal.pcbi.1005595 · 2017 · External reference
Sexually transmitted infections treatment guidelines, 2021
10.15585/mmwr.rr7004a1 · 2021 · External reference
Unresolved reference
External reference
Unresolved reference
External reference
Tree visualization by one table (tvBOT): a web application for visualizing, modifying and annotating phylogenetic trees
10.1093/nar/gkad359 · 2023 · External reference
Molecular screening to track ceftriaxone-resistant FC428-like Neisseria gonorrhoeae strains' dissemination in four provinces of China, 2019 to 2021
10.2807/1560-7917.es.2025.30.6.2400166 · 2025 · External reference
High-level ceftriaxone resistance due to transfer of penA allele 60.001 into endemic gonococcal lineages in Hangzhou, China
10.1093/jac/dkae297 · 2024 · External reference
Emergence, evolution and temporal spread of ceftriaxone-resistant Neisseria gonorrhoeae in China from 2002 to 2022: a retrospective genomic surveillance study
10.1080/22221751.2025.2579397 · 2002 · External reference
Increase in multidrug resistant Neisseria gonorrhoeae FC428-like isolates harboring the mosaic penA 60.001 gene, in Nanjing, China (2017-2020)
10.2147/idr.s408896 · 2017 · External reference
The prevalence and epidemiology of plasmid-mediated penicillin and tetracycline resistance among Neisseria gonorrhoeae isolates in Guangzhou, China, 2002-2012
10.1186/s12879-015-1148-9 · 2015 · External reference
Impact of the gonococcal FC428 penA allele 60.001 on ceftriaxone resistance and biological fitness
10.1080/22221751.2020.1773325 · 2020 · External reference
Ceftriaxone-resistant gonorrhea - China, 2022
10.15585/mmwr.mm7312a2 · 2024 · External reference
