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References from Antibiotic resistance increases evolvability and maximizes opportunities across fitness landscapes. Local targets link to admitted publications; unresolved targets remain external evidence.
Error-prone and error-restrictive mutations affecting ribosomal protein S12
10.1016/j.jmb.2011.04.068 · 2011 · External reference
Voluntary ban on cephalosporin use in Danish pig production has effectively reduced extended-spectrum cephalosporinase-producing Escherichia coli in slaughter pigs
10.1093/jac/dks427 · 2013 · External reference
Mutations in ribosomal proteins S4 and S12 influence the higher order structure of 16 S ribosomal RNA
10.1016/0022-2836(89)90509-3 · 1989 · External reference
Translation rates and misreading characteristics of rpsD mutants in Escherichia coli
10.1007/bf00332630 · 1982 · External reference
Antibiotic resistance and its cost: is it possible to reverse resistance?
10.1038/nrmicro2319 · 2010 · External reference
The biological cost of antibiotic resistance
10.1016/s1369-5274(99)00005-3 · 1999 · External reference
The relationship between the volume of antimicrobial consumption in human communities and the frequency of resistace
10.1073/pnas.96.3.1152 · 1999 · External reference
Definitions and guidelines for research on antibiotic persistence
10.1038/s41579-019-0196-3 · 2019 · External reference
Virulence of antibiotic-resistant Salmonella typhimurium
10.1073/pnas.95.7.3949 · 1998 · External reference
Effects of environment on compensatory mutations to ameliorate costs of antibiotic resistance
10.1126/science.287.5457.1479 · 2000 · External reference
Novel ribosomal mutations affecting translational accuracy, antibiotic resistance and virulence of Salmonella typhimurium
10.1046/j.1365-2958.1999.01142.x · 1999 · External reference
Kinetic impairment of restrictive streptomycin-resistant ribosomes
10.1007/bf00328706 · 1984 · External reference
Tackling antibiotic resistance
10.1038/nrmicro2693 · 2011 · External reference
Phage selection restores antibiotic sensitivity in MDR Pseudomonas aeruginosa
10.1038/srep26717 · 2016 · External reference
10.1201/9781003605942
10.1201/9781003605942 · 2026 · External reference
Chemostats used for studying natural selection and adaptive evolution
10.1016/0076-6879(93)24046-w · 1993 · External reference
Selective neutrality of 6PGD allozymes in E. Coli and the effects of genetic background
10.1093/genetics/96.4.801 · 1980 · External reference
Acetate exposure determines the diauxic behavior of Escherichia coli during the glucose-acetate transition
10.1128/jb.00128-15 · 2015 · External reference
Evolution in the light of fitness landscape theory
10.1016/j.tree.2018.10.009 · 2019 · External reference
Ribosomal protein S12 and aminoglycoside antibiotics modulate A-site mRNA cleavage and transfer-messenger RNA activity in Escherichia coli
10.1074/jbc.m109.062745 · 2009 · External reference
Evolutionary trajectories to antibiotic resistance
10.1146/annurev-micro-090816-093813 · 2017 · External reference
Grofit: fitting biological growth curves with R
10.18637/jss.v033.i07 · 2010 · External reference
Translational accuracy and the fitness of bacteria
10.1146/annurev.ge.26.120192.000333 · 1992 · External reference
Long-term experimental evolution in Escherichia coli. I. Adaptation and divergence during 2,000 generations
10.1086/285289 · 1991 · External reference
The population genetics of antibiotic resistance
10.1093/clinids/24.supplement_1.s9 · 1997 · External reference
Antibiotic stewardship in the intensive care unit
10.1186/s13054-014-0480-6 · 2014 · External reference
Limits to compensatory adaptation and the persistence of antibiotic resistance in pathogenic bacteria
10.1093/emph/eou032 · 2015 · External reference
Adaptation to the deleterious effects of antimicrobial drug resistance mutations by compensatory evolution
10.1016/j.resmic.2004.01.019 · 2004 · External reference
Compensatory adaptation to the deleterious effect of antibiotic resistance in Salmonella typhimurium
10.1046/j.1365-2958.2002.03173.x · 2002 · External reference
Unresolved reference
1992 · External reference
Adaptation of Enterococcus faecalis to daptomycin reveals an ordered progression to resistance
10.1128/aac.01473-13 · 2013 · External reference
Sustained reduction of antibiotic use and low bacterial resistance: 10-year follow-up of the Swedish Strama programme
10.1016/s1473-3099(08)70017-3 · 2008 · External reference
Unresolved reference
1958 · External reference
Adaptive mgl-regulatory mutations and genetic diversity evolving in glucose-limited Escherichia coli populations
10.1046/j.1462-2920.1999.00002.x · 1999 · External reference
The fitness cost of streptomycin resistance depends on rpsL mutation, carbon source and RpoS (sigmaS)
10.1534/genetics.109.106104 · 2009 · External reference
The causes of evolvability and their evolution
10.1038/s41576-018-0069-z · 2019 · External reference
The bacterial ribosome as a target for antibiotics
10.1038/nrmicro1265 · 2005 · External reference
Compensatory evolution in rifampin-resistant Escherichia coli
10.1093/genetics/156.4.1471 · 2000 · External reference
Antibiotic-resistant Staphylococcus aureus and hospital antibiotic policies
10.1016/s0140-6736(70)90585-4 · 1970 · External reference
The evolution of trade-offs: where are we?
10.1111/j.1420-9101.2006.01255.x · 2007 · External reference
Fitness cost of chromosomal drug resistance-conferring mutations
10.1128/aac.46.5.1204-1211.2002 · 2002 · External reference
Reducing antibiotic resistance
10.1038/381120b0 · 1996 · External reference
Adaptation to the fitness costs of antibiotic resistance in Escherichia coli
10.1098/rspb.1997.0178 · 1997 · External reference
The effect of changes in the consumption of macrolide antibiotics on erythomycin resistance in group a streptococci in Finland
10.1056/nejm199708143370701 · 1997 · External reference
Streamlined extract preparation for Escherichia coli-based cell-free protein synthesis by sonication or bead vortex mixing
10.2144/0000113924 · 2012 · External reference
Persistence of tetracycline resistance in pig E. coli
10.1038/258628a0 · 1975 · External reference
Unresolved reference
1995 · External reference
The evolution of resistance to continuously increasing streptomycin concentrations in populations of E. coli
10.1128/aac.01359-15 · 2016 · External reference
The genomic landscape of compensatory evolution
10.1371/journal.pbio.1001935 · 2014 · External reference
The galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2022 update
10.1093/nar/gkac247 · 2022 · External reference
Unresolved reference
2016 · External reference
Evolutionary paths to antibiotic resistance under dynamically sustained drug selection
10.1038/ng.1034 · 2011 · External reference
The effect of banning avoparcin on VRE carriage in the Netherlands
10.1093/jac/46.1.146 · 2000 · External reference
Complex adaptations and the evolution of evolvability
10.1111/j.1558-5646.1996.tb02339.x · 1996 · External reference
Evolutionary implications of Liebig’s law of the minimum: selection under low concentrations of two nonsubstitutable nutrients
10.1002/ece3.3096 · 2017 · External reference
Evolution of high-level resistance during low-level antibiotic exposure
10.1038/s41467-018-04059-1 · 2018 · External reference
EVOLUTION IN MENDELIAN POPULATIONS
10.1093/genetics/16.2.97 · 1931 · External reference
Modes of selection
10.1086/281903 · 1956 · External reference
The shifting balance theory and macroevolution
10.1146/annurev.ge.16.120182.000245 · 1982 · External reference
Variant profiling of evolving prokaryotic populations
10.7717/peerj.2997 · 2017 · External reference
Evolutionary implications of Liebig’s law of the minimum: selection under low concentrations of two nonsubstitutable nutrients
10.1002/ece3.3096 · ExternalCitation · doi-reference
Kinetic impairment of restrictive streptomycin-resistant ribosomes
10.1007/bf00328706 · ExternalCitation · doi-reference
Translation rates and misreading characteristics of rpsD mutants in Escherichia coli
10.1007/bf00332630 · ExternalCitation · doi-reference
Mutations in ribosomal proteins S4 and S12 influence the higher order structure of 16 S ribosomal RNA
10.1016/0022-2836(89)90509-3 · ExternalCitation · doi-reference
Chemostats used for studying natural selection and adaptive evolution
10.1016/0076-6879(93)24046-w · ExternalCitation · doi-reference
Error-prone and error-restrictive mutations affecting ribosomal protein S12
10.1016/j.jmb.2011.04.068 · ExternalCitation · doi-reference
Adaptation to the deleterious effects of antimicrobial drug resistance mutations by compensatory evolution
10.1016/j.resmic.2004.01.019 · ExternalCitation · doi-reference
Evolution in the light of fitness landscape theory
10.1016/j.tree.2018.10.009 · ExternalCitation · doi-reference
Antibiotic-resistant Staphylococcus aureus and hospital antibiotic policies
10.1016/s0140-6736(70)90585-4 · ExternalCitation · doi-reference
The biological cost of antibiotic resistance
10.1016/s1369-5274(99)00005-3 · ExternalCitation · doi-reference
Sustained reduction of antibiotic use and low bacterial resistance: 10-year follow-up of the Swedish Strama programme
10.1016/s1473-3099(08)70017-3 · ExternalCitation · doi-reference
Persistence of tetracycline resistance in pig E. coli
10.1038/258628a0 · ExternalCitation · doi-reference
Reducing antibiotic resistance
10.1038/381120b0 · ExternalCitation · doi-reference
Evolutionary paths to antibiotic resistance under dynamically sustained drug selection
10.1038/ng.1034 · ExternalCitation · doi-reference
The bacterial ribosome as a target for antibiotics
10.1038/nrmicro1265 · ExternalCitation · doi-reference
Antibiotic resistance and its cost: is it possible to reverse resistance?
10.1038/nrmicro2319 · ExternalCitation · doi-reference
Tackling antibiotic resistance
10.1038/nrmicro2693 · ExternalCitation · doi-reference
Evolution of high-level resistance during low-level antibiotic exposure
10.1038/s41467-018-04059-1 · ExternalCitation · doi-reference
The causes of evolvability and their evolution
10.1038/s41576-018-0069-z · ExternalCitation · doi-reference
Definitions and guidelines for research on antibiotic persistence
10.1038/s41579-019-0196-3 · ExternalCitation · doi-reference
Phage selection restores antibiotic sensitivity in MDR Pseudomonas aeruginosa
10.1038/srep26717 · ExternalCitation · doi-reference
Novel ribosomal mutations affecting translational accuracy, antibiotic resistance and virulence of Salmonella typhimurium
10.1046/j.1365-2958.1999.01142.x · ExternalCitation · doi-reference
Compensatory adaptation to the deleterious effect of antibiotic resistance in Salmonella typhimurium
10.1046/j.1365-2958.2002.03173.x · ExternalCitation · doi-reference
Adaptive mgl-regulatory mutations and genetic diversity evolving in glucose-limited Escherichia coli populations
10.1046/j.1462-2920.1999.00002.x · ExternalCitation · doi-reference
The effect of changes in the consumption of macrolide antibiotics on erythomycin resistance in group a streptococci in Finland
10.1056/nejm199708143370701 · ExternalCitation · doi-reference
Virulence of antibiotic-resistant Salmonella typhimurium
10.1073/pnas.95.7.3949 · ExternalCitation · doi-reference
The relationship between the volume of antimicrobial consumption in human communities and the frequency of resistace
10.1073/pnas.96.3.1152 · ExternalCitation · doi-reference
Ribosomal protein S12 and aminoglycoside antibiotics modulate A-site mRNA cleavage and transfer-messenger RNA activity in Escherichia coli
10.1074/jbc.m109.062745 · ExternalCitation · doi-reference
Modes of selection
10.1086/281903 · ExternalCitation · doi-reference
Long-term experimental evolution in Escherichia coli. I. Adaptation and divergence during 2,000 generations
10.1086/285289 · ExternalCitation · doi-reference
The population genetics of antibiotic resistance
10.1093/clinids/24.supplement_1.s9 · ExternalCitation · doi-reference
Limits to compensatory adaptation and the persistence of antibiotic resistance in pathogenic bacteria
10.1093/emph/eou032 · ExternalCitation · doi-reference
Compensatory evolution in rifampin-resistant Escherichia coli
10.1093/genetics/156.4.1471 · ExternalCitation · doi-reference
EVOLUTION IN MENDELIAN POPULATIONS
10.1093/genetics/16.2.97 · ExternalCitation · doi-reference
Selective neutrality of 6PGD allozymes in E. Coli and the effects of genetic background
10.1093/genetics/96.4.801 · ExternalCitation · doi-reference
The effect of banning avoparcin on VRE carriage in the Netherlands
10.1093/jac/46.1.146 · ExternalCitation · doi-reference
Voluntary ban on cephalosporin use in Danish pig production has effectively reduced extended-spectrum cephalosporinase-producing Escherichia coli in slaughter pigs
10.1093/jac/dks427 · ExternalCitation · doi-reference
The galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2022 update
10.1093/nar/gkac247 · ExternalCitation · doi-reference
Adaptation to the fitness costs of antibiotic resistance in Escherichia coli
10.1098/rspb.1997.0178 · ExternalCitation · doi-reference
The evolution of trade-offs: where are we?
10.1111/j.1420-9101.2006.01255.x · ExternalCitation · doi-reference
Complex adaptations and the evolution of evolvability
10.1111/j.1558-5646.1996.tb02339.x · ExternalCitation · doi-reference
Effects of environment on compensatory mutations to ameliorate costs of antibiotic resistance
10.1126/science.287.5457.1479 · ExternalCitation · doi-reference
The evolution of resistance to continuously increasing streptomycin concentrations in populations of E. coli
10.1128/aac.01359-15 · ExternalCitation · doi-reference
Adaptation of Enterococcus faecalis to daptomycin reveals an ordered progression to resistance
10.1128/aac.01473-13 · ExternalCitation · doi-reference
Fitness cost of chromosomal drug resistance-conferring mutations
10.1128/aac.46.5.1204-1211.2002 · ExternalCitation · doi-reference
Acetate exposure determines the diauxic behavior of Escherichia coli during the glucose-acetate transition
10.1128/jb.00128-15 · ExternalCitation · doi-reference
Evolutionary trajectories to antibiotic resistance
10.1146/annurev-micro-090816-093813 · ExternalCitation · doi-reference
The shifting balance theory and macroevolution
10.1146/annurev.ge.16.120182.000245 · ExternalCitation · doi-reference
Translational accuracy and the fitness of bacteria
10.1146/annurev.ge.26.120192.000333 · ExternalCitation · doi-reference
Antibiotic stewardship in the intensive care unit
10.1186/s13054-014-0480-6 · ExternalCitation · doi-reference
10.1201/9781003605942
10.1201/9781003605942 · ExternalCitation · doi-reference
The genomic landscape of compensatory evolution
10.1371/journal.pbio.1001935 · ExternalCitation · doi-reference
The fitness cost of streptomycin resistance depends on rpsL mutation, carbon source and RpoS (sigmaS)
10.1534/genetics.109.106104 · ExternalCitation · doi-reference
Grofit: fitting biological growth curves with R
10.18637/jss.v033.i07 · ExternalCitation · doi-reference
Streamlined extract preparation for Escherichia coli-based cell-free protein synthesis by sonication or bead vortex mixing
10.2144/0000113924 · ExternalCitation · doi-reference
Variant profiling of evolving prokaryotic populations
10.7717/peerj.2997 · ExternalCitation · doi-reference
