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References from Estrobolome dysbiosis in canine mammary gland tumors: Eggerthella lenta as a candidate microbial marker for hormone-dependent mammary tumorigenesis. Local targets link to admitted publications; unresolved targets remain external evidence.
Canine mammary tumors as a model for human disease (Review)
10.3892/ol.2018.8411 · 2018 · External reference
Characterising the response of human breast cancer cells to polyamine modulation
10.3390/biom11050743 · 2021 · External reference
Understanding the polyamine and mTOR pathway interaction in breast cancer cell growth
10.3390/medsci10030051 · 2022 · External reference
Human gut bacterial metabolism drives Th17 activation and colitis
10.1016/j.chom.2021.11.001 · 2022 · External reference
Gut microbiota-derived short-chain fatty acids: impact on cancer treatment response and toxicities
10.3390/microorganisms10102048 · 2022 · External reference
The animal's microbiome and cancer: a translational perspective
10.1111/vco.12892 · 2023 · External reference
Estrogen–gut microbiome axis: physiological and clinical implications
10.1016/j.maturitas.2017.06.025 · 2017 · External reference
Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2
10.1038/s41587-019-0209-9 · 2019 · External reference
The importance of intestinal microbiota and dysbiosis in the context of the development of intestinal lymphoma in dogs and cats
10.3390/cancers16122255 · 2024 · External reference
DADA2: High-resolution sample inference from Illumina amplicon data
10.1038/nmeth.3869 · 2016 · External reference
Host-gut microbiota metabolic interactions and their role in precision diagnosis and treatment of gastrointestinal cancers
10.1016/j.phrs.2024.107321 · 2024 · External reference
Exploring the characteristics of gut microbiota in the development and progression of early-stage colorectal cancer based on metagenomic sequencing
10.3389/fmicb.2025.1658160 · 2025 · External reference
Navigating heme pathways: the breach of heme oxygenase and hemin in breast cancer
10.1007/s11010-024-05119-5 · 2025 · External reference
Identifying the risk factors for malignant mammary tumors in dogs: a retrospective study
10.3390/vetsci10100607 · 2023 · External reference
The warburg effect dictates the mechanism of butyrate-mediated histone acetylation and cell proliferation
10.1016/j.molcel.2012.08.033 · 2012 · External reference
PICRUSt2 for prediction of metagenome functions
10.1038/s41587-020-0548-6 · 2020 · External reference
The role of short chain fatty acids in inflammation and body health
10.3390/ijms25137379 · 2024 · External reference
Meta-analysis of gut microbiome studies identifies disease-specific and shared responses
10.1038/s41467-017-01973-8 · 2017 · External reference
Gut microbial β-glucuronidases reactivate estrogens as components of the estrobolome that reactivate estrogens
10.1074/jbc.ra119.010950 · 2019 · External reference
Microbiome in cancer: a comparative analysis between humans and dogs
10.1016/j.tvjl.2024.106145 · 2024 · External reference
Fecal microbial determinants of fecal and systemic estrogens and estrogen metabolites: a cross-sectional study
10.1186/1479-5876-10-253 · 2012 · External reference
Revisited metabolic control and reprogramming cancers by means of the warburg effect in tumor cells
10.3390/ijms231710037 · 2022 · External reference
Short-chain fatty-acid-producing bacteria: key components of the human gut microbiota
10.3390/nu15092211 · 2023 · External reference
ERα, HER-2, pan-RAS, p53, and aromatase expression in spontaneous malignant canine mammary tumors: prognostic relevance and association with clinicohistological parameters
10.1016/j.rvsc.2024.105515 · 2025 · External reference
Gut microbial beta-glucuronidase: a vital regulator in female estrogen metabolism
10.1080/19490976.2023.2236749 · 2023 · External reference
Comparison of 16S rRNA gene hypervariable regions V3–V4 and V4 sequencing results of gut microbiota in obese children with non-alcoholic fatty liver disease
10.11817/j.issn.1672-7347.2025.240565 · 2025 · External reference
Enterococcus faecalis produces extracellular superoxide and hydrogen peroxide that damages colonic epithelial cell DNA
10.1093/carcin/23.3.529 · 2002 · External reference
Extracellular superoxide production by Enterococcus faecalis requires demethylmenaquinone and is attenuated by functional terminal quinol oxidases
10.1046/j.1365-2958.2001.02638.x · 2001 · External reference
Canine mammary carcinomas: a comparative analysis of altered gene expression
10.3390/vetsci3010001 · 2016 · External reference
The novel diagnostic techniques and biomarkers of canine mammary tumors
10.3390/vetsci9100526 · 2022 · External reference
Hormone, targeted, and combinational therapies for breast cancers: from humans to dogs
10.3390/ijms25020732 · 2024 · External reference
Gut microbiota-derived short-chain fatty acids, T cells, and inflammation
10.4110/in.2014.14.6.277 · 2014 · External reference
From dietary fiber to host physiology: short-chain fatty acids as key bacterial metabolites
10.1016/j.cell.2016.05.041 · 2016 · External reference
Chemical transformation of xenobiotics by the human gut microbiota
10.1126/science.aag2770 · 2017 · External reference
The intestinal microbiome and estrogen receptor-positive female breast cancer
10.1093/jnci/djw029 · 2016 · External reference
The estrobolome: estrogen-metabolizing pathways of the gut microbiome and their relation to breast cancer
10.1002/ijc.35427 · 2025 · External reference
Intestinal proportion of Blautia sp. is associated with clinical stage and histoprognostic grade in patients with early-stage breast cancer
10.1080/01635581.2017.1263750 · 2017 · External reference
Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells
10.1126/science.aan5931 · 2018 · External reference
Role of gut microbiome in cancer treatment
10.1007/s12088-024-01340-4 · 2024 · External reference
Butyrate produced by commensal bacteria potentiates phorbol esters induced AP-1 response in human intestinal epithelial cells
10.1371/journal.pone.0052869 · 2012 · External reference
Canine mammary tumors: classification, biomarkers, traditional and personalized therapies
10.3390/ijms25052891 · 2024 · External reference
Establishment of a canine mammary gland tumor cell line and characterization of its miRNA expression
10.4142/jvs.2016.17.3.385 · 2016 · External reference
Comparison of fine-needle aspiration and core needle biopsy for the pre-operative diagnosis of canine and feline mammary gland tumours
10.1111/vco.13006 · 2024 · External reference
The microbiome–estrogen connection and breast cancer risk
10.3390/cells8121642 · 2019 · External reference
Microbiome and malignancy
10.1016/j.chom.2011.10.003 · 2011 · External reference
The SILVA ribosomal RNA gene database project: improved data processing and web-based tools
10.1093/nar/gks1219 · 2013 · External reference
Comparative oncology using domesticated dogs and their microbiome
10.3389/fvets.2024.1378551 · 2024 · External reference
Heme oxygenase 1 protects human colonocytes against ROS formation, oxidative DNA damage and cytotoxicity induced by heme iron, but not inorganic iron
10.1038/s41419-020-02950-8 · 2020 · External reference
The microbial metabolites, short-chain fatty acids, regulate colonic T reg cell homeostasis
10.1126/science.1241165 · 2013 · External reference
Fine-needle aspiration biopsy of canine mammary gland tumours: a comparison between cytology and histopathology
10.1111/j.1439-0531.2011.01810.x · 2012 · External reference
Unraveling the links between estrogen and gut microbiota in sex-hormone driven cancers
10.5306/wjco.v16.i9.108819 · 2025 · External reference
“The role of short-chain fatty acids in health and disease,”
10.1016/b978-0-12-800100-4.00003-9 · 2014 · External reference
Hormonal carcinogenesis in canine mammary cancer: molecular mechanisms of estradiol involved in malignant progression
10.3390/ani11030608 · 2021 · External reference
Longitudinal changes in gut microbiota composition during endocrine therapy in hormone receptor-positive breast cancer patients
10.1038/s41523-025-00810-2 · 2025 · External reference
From conventional to precision therapy in canine mammary cancer: a comprehensive review
10.3389/fvets.2021.623800 · 2021 · External reference
Canine mammary cancer: state of the art and future perspectives
10.3390/ani13193147 · 2023 · External reference
Gut microbiota as potential biomarker and/or therapeutic target to improve the management of cancer: focus on colibactinaproducing Escherichia coli in colorectal cancer
10.3390/cancers13092215 · 2021 · External reference
Enterococcus faecalis induces aneuploidy and tetraploidy in colonic epithelial cells through a bystander effect
10.1158/0008-5472.can-08-1551 · 2008 · External reference
Microbial dysbiosis is associated with human breast cancer
10.1371/journal.pone.0083744 · 2014 · External reference
Polyamines: their significance for maintaining health and contributing to diseases
10.1186/s12964-023-01373-0 · 2023 · External reference
Comparison of the gut microbiota in patients with benign and malignant breast tumors: a pilot study
10.1177/11769343211057573 · 2021 · External reference
Isolation and characterization of a novel equol-producing bacterium from human feces
10.1271/bbb.80329 · 2008 · External reference
The relationship between clinicopathological features and expression of epithelial and mesenchymal markers in spontaneous canine mammary gland tumors
10.1292/jvms.14-0104 · 2014 · External reference
The Relationship of tumor microbiome and oral bacteria and intestinal dysbiosis in canine mammary tumor
10.3390/ijms231810928 · External reference
Epidemiological investigation of canine mammary tumors in mainland China Between 2017 and 2021
10.3389/fvets.2022.843390 · External reference
