References

Sleep loss promotes astrocytic phagocytosis and microglial activation in mouse cerebral cortex

10.1523/jneurosci.3981-16.2017 · 2017 · External reference

Gut microbiota and glucometabolic alterations in response to recurrent partial sleep deprivation in normal-weight young individuals

10.1016/j.molmet.2016.10.003 · 2016 · External reference

Estimation of the global prevalence and burden of insomnia: a systematic literature review-based analysis

10.1016/j.smrv.2025.102121 · 2025 · External reference

Repeated sleep disruption in mice leads to persistent shifts in the fecal microbiome and metabolome

10.1371/journal.pone.0229001 · 2020 · External reference

The gut microbiota influences blood-brain barrier permeability in mice

10.1126/scitranslmed.3009759 · 2014 · External reference

Sishen pill treatment of DSS-induced colitis via regulating interaction with inflammatory dendritic cells and gut microbiota

10.3389/fphys.2020.00801 · 2020 · External reference

Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system

10.1038/s41467-020-19931-2 · 2020 · External reference

The microbiota-gut-brain axis

10.1152/physrev.00018.2018 · 2019 · External reference

The role of short-chain fatty acids in microbiota-gut-brain communication

10.1038/s41575-019-0157-3 · 2019 · External reference

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study

10.1038/s41591-019-0495-2 · 2019 · External reference

A brief period of sleep deprivation leads to subtle changes in mouse gut microbiota

10.1111/jsr.12920 · 2020 · External reference

Host microbiota constantly control maturation and function of microglia in the CNS

10.1038/nn.4030 · 2015 · External reference

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

10.1073/pnas.1219451110 · 2013 · External reference

Altered hippocampal transcriptome dynamics following sleep deprivation

10.1186/s13041-021-00835-1 · 2021 · External reference

Melatonin-mediated colonic microbiota metabolite butyrate prevents acute sleep deprivation-induced colitis in mice

10.3390/ijms222111894 · 2021 · External reference

Butyrate ameliorates insufficient sleep-induced intestinal mucosal damage in humans and mice

10.1128/spectrum.02000-22 · 2023 · External reference

Role of melatonin in sleep deprivation-induced intestinal barrier dysfunction in mice

10.1111/jpi.12574 · 2019 · External reference

Sishen pill ameliorates dextran sulfate sodium-induced colitis with spleen-kidney yang deficiency syndromes: role of gut microbiota, fecal metabolites, inflammatory dendritic cells, and TLR4/NF-κB pathway

10.1155/2022/6132289 · 2022 · External reference

Gut dysbiosis induces the development of depression-like behavior through abnormal synapse pruning in microglia-mediated by complement C3

10.1186/s40168-024-01756-6 · 2024 · External reference

Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1

10.7554/elife.13424 · 2016 · External reference

Gut microbiome promotes mice recovery from stress-induced depression by rescuing hippocampal neurogenesis

10.1016/j.nbd.2023.106396 · 2024 · External reference

Microbiota basis of antidepressant effects of Zhi-zi-chi decoction: Lactobacillus rhamnosus and gut microbiota metabolism

10.1016/j.chmed.2025.05.001 · 2025 · External reference

Integrated metabolomics and proteomics analysis reveals energy metabolism disorders in the livers of sleep-deprived mice

10.1016/j.jprot.2021.104290 · 2021 · External reference

Jiaotaiwan activates serum SCFAs and upregulates cAMP-PKA-CREB-BDNF signaling pathway for antidepressant effects: a multicenter, randomized, controlled study

10.1016/j.chmed.2025.03.002 · 2025 · External reference

Short sleep duration and health outcomes: a systematic review, meta-analysis, and meta-regression

10.1016/j.sleep.2016.08.006 · 2017 · External reference

Jia Wei Xiao Yao san ameliorates chronic stress-induced depression-like behaviors in mice by regulating the gut microbiome and brain metabolome in relation to purine metabolism

10.1016/j.phymed.2022.153940 · 2022 · External reference

Severe, short-term sleep restriction reduces gut microbiota community richness but does not alter intestinal permeability in healthy young men

10.1038/s41598-023-27463-0 · 2023 · External reference

Transferring the blues: depression-associated gut microbiota induces neurobehavioural changes in the rat

10.1016/j.jpsychires.2016.07.019 · 2016 · External reference

Fecal microbiota transplantation repairs intestinal permeability and regulates the expression of 5-HT to influence alcohol-induced depression-like behaviors in C57BL/6J mice

10.3389/fmicb.2023.1241309 · 2024 · External reference

Chronic sleep deprivation causes anxiety, depression and impaired gut barrier in female mice: correlation analysis from fecal microbiome and metabolome

10.3390/biomedicines12122654 · 2024 · External reference

Fecal microbiota transplantation from chronic unpredictable mild stress mice donors affects anxiety-like and depression-like behavior in recipient mice via the gut microbiota-inflammation-brain axis

10.1080/10253890.2019.1617267 · 2019 · External reference

Transformation of psoralen and isopsoralen by human intestinal microbial in vitro, and the biological activities of its metabolites

10.3390/molecules24224080 · 2019 · External reference

Microbiota-gut-brain axis: natural antidepressants molecular mechanism

10.1016/j.phymed.2024.156012 · 2024 · External reference

Sleep deprivation induced by the modified multiple platform technique: quantification of sleep loss and recovery

10.1016/j.brainres.2004.01.019 · 2004 · External reference

Associations between fecal short-chain fatty acids and sleep continuity in older adults with insomnia symptoms

10.1038/s41598-021-83389-5 · 2021 · External reference

Sleep, circadian rhythm, and gut microbiota

10.1016/j.smrv.2020.101340 · 2020 · External reference

Artemisia argyi polysaccharide alleviates intestinal inflammation and intestinal flora dysbiosis in lipopolysaccharide-treated mice

10.26599/fmh.2024.9420008 · 2024 · External reference

Chronic sleep disruption alters gut microbiota, induces systemic and adipose tissue inflammation and insulin resistance in mice

10.1038/srep35405 · 2016 · External reference

Gut microbiome and metabolic pathways linked to sleep quality

10.3389/fmicb.2024.1418773 · 2024 · External reference

Sleep deprivation disrupts diurnal rhythmicity of gut microbiota and blood inflammatory cytokines in mice

10.1371/journal.pone.0335754 · 2025 · External reference

Xiao-chai-Hu-tang ameliorates tumor growth in cancer comorbid depressive symptoms via modulating gut microbiota-mediated TLR4/MyD88/NF-κB signaling pathway

10.1016/j.phymed.2021.153606 · 2021 · External reference

Potential of Dendrobium officinale oligosaccharides to alleviate chronic colitis by modulating inflammation and gut microbiota

10.26599/fmh.2025.9420077 · 2025 · External reference

The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis

10.1126/science.1241165 · 2013 · External reference

Butyrate, a metabolite of intestinal bacteria, enhances sleep

10.1038/s41598-019-43502-1 · 2019 · External reference

Spatial transcriptomics reveals unique gene expression changes in different brain regions after sleep deprivation

10.1038/s41467-023-42751-z · 2023 · External reference

Gut microbiota modulates the inflammatory response and cognitive impairment induced by sleep deprivation

10.1038/s41380-021-01113-1 · 2021 · External reference

Zuojin pill improves chronic unpredictable stress-induced depression-like behavior and gastrointestinal dysfunction in mice via the TPH2/5-HT pathway

10.1016/j.phymed.2023.155067 · 2023 · External reference

Gut microbiota-derived metabolites mediate the neuroprotective effect of melatonin in cognitive impairment induced by sleep deprivation

10.1186/s40168-022-01452-3 · 2023 · External reference

Gut microbiota regulate insomnia-like behaviors via gut-brain metabolic axis

10.1038/s41380-024-02867-0 · 2025 · External reference

Sishen wan ameliorated trinitrobenzene-sulfonic-acid-induced chronic colitis via NEMO/NLK signaling pathway

10.3389/fphar.2019.00170 · 2019 · External reference

Sishen wan treats ulcerative colitis in rats by regulating gut microbiota and restoring the Treg/Th17 balance

10.1155/2022/1432816 · 2022 · External reference

Metabolomics changes in brain-gut axis after unpredictable chronic mild stress

10.1007/s00213-021-05958-w · 2022 · External reference

Acute sleep deprivation exacerbates systemic inflammation and psychiatry disorders through gut microbiota dysbiosis and disruption of circadian rhythms

10.1016/j.micres.2022.127292 · 2023 · External reference

Traditional Chinese herbal formulas modulate gut microbiome and improve insomnia in patients with distinct syndrome types: insights from an interventional clinical study

10.3389/fcimb.2024.1395267 · 2024 · External reference

Sleep deprivation-induced anxiety-like behaviors are associated with alterations in the gut microbiota and metabolites

10.1128/spectrum.01437-23 · 2024 · External reference

Integrated gut microbiome and metabolomic analyses elucidate the therapeutic mechanisms of Suanzaoren decoction in insomnia and depression models

10.3389/fnins.2024.1459141 · 2024 · External reference

Association of sleep duration and risk of mental disorder: a systematic review and meta-analysis

10.1007/s11325-023-02905-1 · 2024 · External reference

Gan-Mai-Da-Zao decoction ameliorates depressive-like behaviors in CUMS mice via the microbiota-metabolism-inflammation axis

10.1016/j.phymed.2025.157018 · 2025 · External reference

Evolving interplay between natural products and gut microbiota

10.1016/j.ejphar.2023.175557 · 2023 · External reference

Untargeted metabolome atlas for sleep-related phenotypes in the Hispanic community health study/study of Latinos

10.1016/j.ebiom.2024.105507 · 2025 · External reference

Intestinal dysbiosis mediates cognitive impairment via the intestine and brain NLRP3 inflammasome activation in chronic sleep deprivation

10.1016/j.bbi.2022.11.013 · 2023 · External reference

Modified Xiaoyaosan rescues depression-like behavior via remodeling gut microbiota and leucine metabolism

10.1016/j.phymed.2025.157241 · 2025 · External reference

Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host's metabolism

10.1038/mp.2016.44 · 2016 · External reference

Chlorogenic acid improves the cognitive deficits of sleep-deprived mice via regulation of immunity function and intestinal flora

10.1016/j.phymed.2023.155194 · 2024 · External reference