Research graph
References from Heterogeneous mechanisms, risk stratification, and translational advances in the malignant transformation of oral potentially malignant disorders to oral squamous cell carcinoma. Local targets link to admitted publications; unresolved targets remain external evidence.
Artificial intelligence for predicting post-excision recurrence and malignant progression in oral potentially malignant disorders: a retrospective cohort study
10.1097/js9.0000000000003592 · 2026 · External reference
A deep learning system to predict epithelial dysplasia in oral leukoplakia
10.1177/00220345241272048 · 2024 · External reference
Association of genetic polymorphisms in interferon-γ, interleukin-6 and transforming growth factor-β1 gene with oral Lichen planus susceptibility
10.1186/s12903-016-0277-x · 2016 · External reference
Identification of proteomic biomarkers in proliferative verrucous leukoplakia through liquid chromatography with tandem mass spectrometry
10.1016/j.labinv.2023.100222 · 2023 · External reference
Treatment of oral erosive Lichen planus with upadacitinib
10.1001/jamadermatol.2022.0147 · 2022 · External reference
Salivary biomarkers for oral cancer detection: an exploratory systematic review
10.3390/ijms25052634 · 2024 · External reference
Identification of high-risk oral leukoplakia (OLK) using combined raman spectroscopic analysis of brush biopsy and saliva samples: a proof of concept study
10.1016/j.saa.2025.125721 · 2025 · External reference
Dysbiosis and interactions of the mycobiome and bacteriome in mucosal lesions of erosive and non-erosive oral Lichen planus patients
10.1080/20002297.2024.2374639 · 2024 · External reference
Recurrence in oral leukoplakia: a systematic review and meta-analysis
10.1177/00220345241266519 · 2024 · External reference
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
10.3322/caac.21834 · 2024 · External reference
Proliferative verrucous leukoplakia and erythroplakia are probably the disorders with the highest rate of malignant transformation
10.1016/j.adaj.2020.01.035 · 2020 · External reference
Molecular mechanisms in the carcinogenesis of oral squamous cell carcinoma: a literature review
10.3390/biom15050621 · 2025 · External reference
Biomarkers of malignant transformation in oral leukoplakia: from bench to bedside
10.1631/jzus.b2200589 · 2023 · External reference
Copy number alterations predict development of OSCC from oral leukoplakia
10.1177/00220345231217160 · 2024 · External reference
Identification of genomic alteration and prognosis using pathomics-based artificial intelligence in oral leukoplakia and head and neck squamous cell carcinoma: a multicenter experimental study
10.1097/js9.0000000000002077 · 2025 · External reference
Meis1 negatively regulates epithelial-mesenchymal transition via Wnt/β-catenin pathway in oral submucous fibrosis
10.1016/j.identj.2025.109323 · 2026 · External reference
Oral leukoplakia and risk of progression to oral cancer: a population-based cohort study
10.1093/jnci/djz238 · 2020 · External reference
HOXC-AS1 and EZH2 interaction increase HOXC9 expression and promote the malignant transformation of oral leukoplakia
10.7150/jca.103482 · 2025 · External reference
Single cell dissection reveals SFRP2+ fibroblasts amplifying inflammatory responses in oral lichen planus
10.3389/fimmu.2025.1553963 · 2025 · External reference
Are there betel quid mixtures less harmful than others? A scoping review of the association between different betel quid ingredients and the risk of oral submucous fibrosis
10.3390/biom12050664 · 2022 · External reference
Implications of podoplanin overexpression in the malignant transformation of oral potentially malignant disorders: a systematic review and meta-analysis
10.3390/cancers17213448 · 2025 · External reference
A simple clinicaapproach to diagnose oral erythroplakia, the potentially malignant disorder with the highest rate of malignant development into squamous cell carcinoma
10.1016/j.oraloncology.2022.106126 · 2022 · External reference
Oral Lichen planus and oral squamous cell carcinoma share key oncogenic signatures
10.1038/s41598-022-24801-6 · 2022 · External reference
SOX2 expression is an independent predictor of oral cancer progression
10.3390/jcm8101744 · 2019 · External reference
Emerging role of decoy Receptor-2 as a cancer risk predictor in oral potentially malignant disorders
10.3390/ijms241814382 · 2023 · External reference
Microenvironment in oral potentially malignant disorders: multi-dimensional characteristics and mechanisms of carcinogenesis
10.3390/ijms23168940 · External reference
Cell-free DNA promotes inflammation in patients with oral Lichen planus via the STING pathway
10.3389/fimmu.2022.838109 · External reference
Updates on immunological mechanistic insights and targeting of the oral Lichen planus microenvironment
10.3389/fimmu.2022.1023213 · External reference
Incidence trends of lip, oral cavity, and pharyngeal cancers: global burden of disease 1990-2017
10.1177/0022034519894963 · 2020 · External reference
Adhesive lipophilic gels delivering rapamycin prevent oral leukoplakia from malignant transformation
10.1016/j.mtbio.2024.101305 · 2024 · External reference
Different approaches to oral Lichen planus treatment: a narrative review
10.3390/ijms27020914 · 2026 · External reference
Immune mechanisms in oral lichen planus
10.1111/odi.14142 · 2023 · External reference
Exploring topical atorvastatin hyalurosomal gel as an adjuvant for reducing systemic corticosteroid dosage: a randomized clinical trial in severe oral lichen planus patients
10.1007/s13346-025-01956-z · 2026 · External reference
FTO deficiency facilitates epithelia dysfunction in oral lichen planus
10.1016/j.omtn.2025.102463 · 2025 · External reference
Global gene expression profile of proliferative verrucous leukoplakia and its underlying biological disease mechanisms
10.1016/j.oraloncology.2024.106737 · 2024 · External reference
Expression of cancer stem cell markers ALDH1 and Bmi1 in oral erythroplakia and the risk of oral cancer
10.1111/j.1600-0714.2012.01191.x · 2013 · External reference
Advancing oral leukoplakia progression recognition: a benchmark with dataset, method, and application
10.1016/j.neunet.2025.108256 · 2026 · External reference
High density of CD8 T cell and immune imbalance of T lymphocytes subsets are associated with proliferative verrucous leukoplakia
10.1111/imm.13565 · 2023 · External reference
Clinical management update of oral leukoplakia: a review from the American head and neck society cancer prevention service
10.1002/hed.28013 · 2025 · External reference
The evolutionary history of 2,658 cancers
10.1038/s41586-019-1907-7 · 2020 · External reference
Integrative analysis of genomic and transcriptomic data of normal, tumour, and co-occurring leukoplakia tissue triads drawn from patients with gingivobuccal oral cancer identifies signatures of tumour initiation and progression
10.1002/path.5900 · 2022 · External reference
Cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life years for 29 cancer groups from 2010 to 2019: a systematic analysis for the global burden of disease study 2019
10.1001/jamaoncol.2021.6987 · 2022 · External reference
Cancer hallmarks expression in oral leukoplakia: systematic review and meta-analysis
10.1111/odi.70106 · 2026 · External reference
Malignant transformation risk of oral lichen planus: a systematic review and comprehensive meta-analysis
10.1016/j.oraloncology.2019.07.012 · 2019 · External reference
A scoping review on gaps in the diagnostic criteria for proliferative verrucous leukoplakia: a conceptual proposal and diagnostic evidence-based criteria
10.3390/cancers13153669 · 2021 · External reference
Hallmarks of cancer expression in oral lichen planus: a scoping review of systematic reviews and meta-analyses
10.3390/ijms232113099 · 2022 · External reference
Molecular screening of oral precancer
10.1016/j.oraloncology.2013.09.005 · 2013 · External reference
Oral submucous fibrosis: an overview of a challenging entity
10.25259/ijdvl_371_20 · 2021 · External reference
The association of candida and antifungal therapy with pro-inflammatory cytokines in oral leukoplakia
10.1007/s00784-021-03927-3 · 2021 · External reference
The interplay of hypoxia, inflammation, and microbiota as indicators of malignant transformation in oral potentially malignant disorders
10.1016/j.oraloncology.2025.107583 · 2025 · External reference
Nivolumab for patients with high-risk oral leukoplakia: a nonrandomized controlled trial
10.1001/jamaoncol.2023.4853 · 2024 · External reference
MicroRNA-375 as a biomarker for malignant transformation in oral lesions
10.1016/j.oooo.2016.07.022 · 2016 · External reference
Differentially methylated genes in proliferative verrucous leukoplakia reveal potential malignant biomarkers for oral squamous cell carcinoma
10.1016/j.oraloncology.2021.105191 · 2021 · External reference
The effects of photodynamic and low-level laser therapy for treatment of oral lichen planus-A systematic review and meta-analysis
10.1016/j.pdpdt.2018.07.001 · 2018 · External reference
Deciphering the pharmacological mechanisms of Scutellaria baicalensis georgi on oral leukoplakia by combining network pharmacology, molecular docking and experimental evaluations
10.1016/j.phymed.2022.154195 · 2022 · External reference
Oral submucous fibrosis: regulatory mechanism of collagen metabolism and management
10.1016/j.biopha.2026.119053 · External reference
Fumarate loss destabilizes mitochondria and activates cGAS-STING in OLP
10.1016/j.biopha.2026.119127 · External reference
Deregulation of circ_003912 contributes to pathogenesis of erosive oral Lichen planus by via sponging microRNA-123, -647 and -31 and upregulating FOXP3
10.1186/s10020-021-00382-4 · 2021 · External reference
The antifibrotic and the anticarcinogenic activity of capsaicin in hot chili pepper in relation to oral submucous fibrosis
10.3389/fphar.2022.888280 · 2022 · External reference
MicroRNA-31 upregulation predicts increased risk of progression of oral potentially malignant disorder
10.1016/j.oraloncology.2015.11.017 · 2016 · External reference
Potential role of INTERLEUKIN-17 in the pathogenesis of oral lichen planus: a systematic review with META-analysis
10.1111/jdv.18219 · 2022 · External reference
Potentially malignant disorders of the oral cavity and oral dysplasia: a systematic review and meta-analysis of malignant transformation rate by subtype
10.1002/hed.26006 · 2020 · External reference
Accumulative increase of loss of heterozygosity from leukoplakia to foci of early cancerization in leukoplakia of the oral cavity
10.1002/1097-0142(20011101)92:9<2349::aid-cncr1582>3.0.co;2-i · 2001 · External reference
Migrasome-transported PTGES amplifies the PGE2 cascade in SPP1+ macrophages to drive oral leukoplakia carcinogenesis
10.1038/s41467-026-70824-2 · 2026 · External reference
A systematic review of MicroRNA signatures associated with the progression of leukoplakia with and without epithelial dysplasia
10.3390/biom11121879 · 2021 · External reference
A molecular hypothesis on malignant transformation of oral lichen planus: a systematic review and meta-analysis of cancer hallmarks expression in this oral potentially malignant disorder
10.3390/cancers16152614 · 2024 · External reference
Trace elements (copper, zinc, selenium and molybdenum) as markers in oral sub mucous fibrosis and oral squamous cell carcinoma
10.1016/j.jtemb.2013.04.003 · 2013 · External reference
Oral epithelial dysplasia grading systems: a systematic review and meta-analysis
10.1177/10668969211070171 · 2022 · External reference
Bacterial extracellular vesicles as potential promoting factors for oral Lichen planus pathogenesis
10.1007/s10753-024-02146-8 · 2025 · External reference
Upregulation of epidermal growth factor receptor 4 in oral leukoplakia
10.1038/ijos.2013.10 · 2013 · External reference
Oral potentially malignant disorders: etiology, pathogenesis, and transformation into oral cancer
10.3389/fphar.2022.825266 · 2022 · External reference
Compositional and functional changes in the salivary microbiota related to oral leukoplakia and oral squamous cell carcinoma: a case control study
10.1186/s12903-023-03760-y · 2023 · External reference
Chemopreventive potential of artemisinin and Rubus occidentalis in the progression of oral leukoplakia to oral cancer: a preclinical murine study
10.3390/ijms26178120 · 2025 · External reference
Avelumab plus standard-of-care chemoradiotherapy versus chemoradiotherapy alone in patients with locally advanced squamous cell carcinoma of the head and neck: a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial
10.1016/s1470-2045(20)30737-3 · 2021 · External reference
YAP-induced endothelial-mesenchymal transition in oral submucous fibrosis
10.1177/0022034519851804 · 2019 · External reference
Improvement in the risk assessment of oral leukoplakia through morphology-related copy number analysis
10.1007/s11427-021-1965-x · 2021 · External reference
Single-cell immune profiling reveals immune responses in oral Lichen planus
10.3389/fimmu.2023.1182732 · External reference
Low-dose arecoline regulates distinct core signaling pathways in oral submucous fibrosis and oral squamous cell carcinoma
10.1186/s12903-023-02887-2 · External reference
Expression of FAP in oral leukoplakia and oral squamous cell carcinoma
10.1016/j.identj.2023.12.011 · 2024 · External reference
FAP promotes progression of oral leukoplakia via activation of PI3K/AKT pathway by interacting with ITGB1
10.1016/j.tranon.2025.102531 · External reference
The small GTP-Binding Ras-like protein DIRAS2 promotes cell proliferation in oral leukoplakia via the RAF/MEK/MAPK pathway
10.1016/j.tice.2025.103037 · External reference
SOX11 and GLIS2: novel biomarkers for understanding the progression of oral leukoplakia
10.1016/j.identj.2025.100872 · External reference
Heat shock protein 70-2 is overexpressed in oral leukoplakia and oral squamous cell carcinoma
10.1016/j.identj.2024.10.008 · External reference
Next-generation AI framework for comprehensive oral leukoplakia evaluation and management
10.1038/s41746-025-01885-8 · External reference
BMP5 mediates macrophage-driven oral leukoplakia carcinogenesis
10.1016/j.intimp.2026.116232 · 2026 · External reference
Aberrantly downregulated FENDRR by arecoline elevates ROS and myofibroblast activation via mitigating the miR-214/MFN2 axis
10.1016/j.ijbiomac.2024.130504 · 2024 · External reference
Salivary biomarkers: effective diagnostic tool for oral leukoplakia and oral squamous cell carcinoma
10.1111/odi.14835 · 2024 · External reference
Multifunctional photodynamic/photothermal nano-agents for the treatment of oral leukoplakia
10.1186/s12951-022-01310-2 · 2022 · External reference
Adhesive hydrogel delivering ALA prevents the malignant transformation of oral leukoplakia
10.1016/j.mtbio.2026.103017 · 2026 · External reference
Proliferative verrucous leukoplakia is associated with aggressive periodontal pathogens: a comparative study with oral lichen planus and chronic periodontitis cases
10.1007/s00784-025-06525-9 · 2025 · External reference
Expression patterns of cancer stem cell markers ALDH1 and CD133 correlate with a high risk of malignant transformation of oral leukoplakia
10.1002/ijc.27720 · 2013 · External reference
Immune expression profile identification in a group of proliferative verrucous leukoplakia patients: a pre-cancer niche for oral squamous cell carcinoma development
10.1007/s00784-020-03575-z · 2021 · External reference
Critical update, systematic review, and meta-analysis of oral erythroplakia as an oral potentially malignant disorder
10.1111/jop.13304 · 2022 · External reference
Oral lichen planus: an update on diagnosis and management
10.1007/s40257-023-00814-3 · 2024 · External reference
Laser therapy decreases oral leukoplakia recurrence and boosts patient comfort: a network meta-analysis and systematic review
10.1186/s12903-024-04179-9 · 2024 · External reference
Etiopathogenesis of oral lichen planus: a review
10.1007/s12105-025-01807-w · 2025 · External reference
Acetaldehyde production and microbial colonization in oral squamous cell carcinoma and oral lichenoid disease
10.1016/j.oooo.2013.02.009 · 2013 · External reference
Podoplanin expression independently and jointly with oral epithelial dysplasia grade acts as a potential biomarker of malignant transformation in oral leukoplakia
10.3390/biom12050606 · 2022 · External reference
Oral cancer and precancerous lesions
10.3322/canjclin.52.4.195 · 2002 · External reference
A meta-analysis reveals the protein profile associated with malignant transformation of oral leukoplakia
10.3389/froh.2023.1088022 · 2023 · External reference
Oral epithelial dysplasia: Recognition, grading and clinical significance
10.1111/odi.13993 · 2021 · External reference
Oral erythroplakia and oral erythroplakia-like oral squamous cell carcinoma - what’s the difference?
10.1186/s12903-023-03619-2 · 2023 · External reference
Macrophages CD163+ and factor XIIIa+ provide a first-line defence against proliferative verrucous Leukoplakia antigens
10.3390/ijms24065242 · 2023 · External reference
Oral proliferative verrucous leukoplakia: progression to malignancy and clinical implications. Systematic review and meta-analysis
10.3390/cancers13164085 · 2021 · External reference
Qualitative assessment of collagen and elastic fibers in oral submucous fibrosis (OSMF), OSMF with dysplasia and oral squamous cell carcinoma arising from OSMF: a histochemical study
10.1007/s12105-023-01591-5 · 2023 · External reference
Role of areca nut induced JNK/ATF2/Jun axis in the activation of TGF-β pathway in precancerous oral submucous fibrosis
10.1038/srep34314 · 2016 · External reference
The potential roles of cigarette smoke-induced extracellular vesicles in oral leukoplakia
10.1186/s40001-023-01217-0 · 2023 · External reference
Apremilast in oral Lichen planus - a multicentric, retrospective study
10.1111/ddg.14696 · 2022 · External reference
Malignant transformation of oral leukoplakia: systematic review and comprehensive meta-analysis
10.1111/odi.15140 · 2025 · External reference
Efficacy of hydroxychloroquine in oral lichen planus: a retrospective review
10.1093/bjd/ljac113 · 2023 · External reference
Reactive oxygen species (ROS) and cancer: role of antioxidative nutraceuticals
10.1016/j.canlet.2016.03.042 · 2017 · External reference
Targeting the genetic landscape of oral potentially malignant disorders has the potential as a preventative strategy in oral cancer
10.1016/j.canlet.2021.05.025 · 2021 · External reference
A high prevalence of p53 mutations in pre-malignant oral erythroplakia
10.1002/(sici)1097-0215(19990129)80:3<345::aid-ijc2>3.0.co;2-n · 1999 · External reference
Oral submucous fibrosis: etiological mechanism, malignant transformation, therapeutic approaches and targets
10.3390/ijms24054992 · 2023 · External reference
Significance of cytoplasmic cyclin D1 expression in oral oncogenesis
10.1111/odi.12752 · 2018 · External reference
Oral cancer development in Lichen planus and related conditions-3.0 evidence level: a systematic review of systematic reviews
10.1111/odi.13812 · 2021 · External reference
Significance of p53 overexpression in the prediction of the malignant transformation risk of oral potentially malignant disorders: a systematic review and meta-analysis
10.1016/j.oraloncology.2022.105734 · 2022 · External reference
Genetic changes driving immunosuppressive microenvironments in oral premalignancy
10.3389/fimmu.2022.840923 · 2022 · External reference
Immunohistochemical coexpression of MUC1 and MUC4 in oral leukoplakia and oral squamous cell carcinoma
10.1007/s12105-021-01291-y · 2021 · External reference
Oral and non-oral lichen planus show genetic heterogeneity and differential risk for autoimmune disease and oral cancer
10.1016/j.ajhg.2024.04.020 · 2024 · External reference
Betel quid chewing, oral cancer and other oral mucosal diseases in Vietnam: a review
10.1111/j.1600-0714.2008.00669.x · 2008 · External reference
Oxidative stress, inflammation, and cancer: how are they linked?
10.1016/j.freeradbiomed.2010.09.006 · 2010 · External reference
Multimodal serum profiling for early detection and risk assessment of oral potentially malignant disorders and oral cancer
10.1021/acs.analchem.5c06663 · 2026 · External reference
Does a link exist between oral microbiota and oral squamous cell carcinoma? A review of current insights
10.1080/20002297.2025.2569934 · 2025 · External reference
A comprehensive analysis of the role of oxidative stress in the pathogenesis and chemoprevention of oral submucous fibrosis
10.3390/antiox11050868 · 2022 · External reference
Predicting the clinical outcome of oral potentially malignant disorders using transcriptomic-based molecular pathology
10.1038/s41416-021-01411-z · 2021 · External reference
Topical imiquimod for oral cavity leukoplakia and dysplasia: a scoping review
10.1002/ohn.70107 · 2026 · External reference
Salivary microRNA- 375: a novel biomarker in the malignant transformation of oral potentially malignant disorders
10.1016/j.oraloncology.2022.106065 · 2022 · External reference
Erythroplakia of the oral cavity
10.1002/1097-0142(197509)36:3<1021::aid-cncr2820360327>3.0.co;2-w · 1975 · External reference
Novel transcripts of EMT driving the malignant transformation of oral submucous fibrosis
10.1038/s41598-025-87790-2 · 2025 · External reference
Manganese suppresses the development of oral leukoplakia by activating the immune response
10.1111/odi.14412 · 2024 · External reference
Recent advancements in artificial intelligence-powered cancer prediction from oral microbiome
10.1111/prd.70000 · 2025 · External reference
Long-term efficacy of 5-ALA photodynamic therapy in oral Lichen planus patients
10.3390/ph18111676 · 2025 · External reference
Upregulation of HIF-1alpha in malignant transformation of oral submucous fibrosis
10.1111/j.1600-0714.2007.00625.x · 2008 · External reference
Oral squamous cell carcinomas: state of the field and emerging directions
10.1038/s41368-023-00249-w · 2023 · External reference
Oral submucous fibrosis: pathogenesis and therapeutic approaches
10.1038/s41368-024-00344-6 · 2025 · External reference
Risk assessment for malignant transformation in patients with oral proliferative leukoplakia: a 10-Year retrospective cohort study
10.3390/cancers18010002 · 2025 · External reference
Proliferative verrucous leukoplakia: an expert consensus guideline for standardized assessment and reporting
10.1007/s12105-020-01262-9 · 2021 · External reference
Oral submucous fibrosis: review on aetiology and pathogenesis
10.1016/j.oraloncology.2005.08.005 · 2006 · External reference
Multiplex immunofluorescence assessment of macrophages and IL-23R in inflammatory and malignant diseases of the oral mucosa: a pilot study
10.3389/fimmu.2025.1569490 · 2025 · External reference
Multiple pathways in the FGF signaling network are frequently deregulated by gene amplification in oral dysplasias
10.1002/ijc.24611 · 2009 · External reference
A retrospective 20-Year analysis of proliferative verrucous leukoplakia and its progression to malignancy and association with high-risk human papillomavirus
10.1007/s12105-018-0893-7 · 2018 · External reference
The molecular interplay between oral microbiome and oral cancer pathogenesis
10.3390/ijms262010212 · 2025 · External reference
Outcome and long-term treatment protocol for topical tacrolimus in oral Lichen planus
10.1111/jdv.18457 · 2022 · External reference
Diagnostic value of serum and salivary podoplanin as clinical biomarkers for distinguishing oral cancer from oral leukoplakia
10.3390/diagnostics16020206 · 2026 · External reference
Oral cancer and oral erythroplakia: an update and implication for clinicians
10.1111/j.1834-7819.2011.01337.x · 2011 · External reference
Oncological outcomes of patients with oral potentially malignant disorders
10.1001/jamaoto.2024.3719 · 2025 · External reference
Oral acitretin plus topical triamcinolone vs topical triamcinolone monotherapy in patients with symptomatic oral lichen planus: a randomized clinical trial
10.1001/jamadermatol.2023.4889 · 2024 · External reference
Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy adults
10.1002/14651858.cd010173.pub3 · 2021 · External reference
Sensitive detection of oral leukoplakia: analyzing P90 biomarkers in saliva and tissue
10.3390/bios14060281 · 2024 · External reference
PA28γ induces dendritic cell maturation and activates T-cell immune responses in oral lichen planus
10.1002/mco2.561 · 2024 · External reference
White, red, and mixed lesions of oral mucosa: a clinicopathologic approach to diagnosis
10.1111/prd.12276 · 2019 · External reference
Oral potentially malignant disorders: a consensus report from an international seminar on nomenclature and classification, convened by the WHO collaborating centre for oral cancer
10.1111/odi.13704 · 2021 · External reference
Aberrant accumulation of cell-free DNA activates the cGAS-STING-TBK1 pathway of γδ T cells to promote the inflammatory responses in oral Lichen planus
10.1007/s10753-025-02416-z · 2026 · External reference
Elucidating the genetic landscape of oral leukoplakia to predict malignant transformation
10.1158/1078-0432.ccr-22-2210 · 2023 · External reference
Salivary oxidative stress and antioxidant markers in oral leukoplakia: a systematic review and meta-analysis
10.3390/antiox15020218 · 2026 · External reference
Integrated multi-omics analyses of oral squamous cell carcinoma reveal precision patient stratification and personalized treatment strategies
10.1016/j.canlet.2025.217482 · 2025 · External reference
Metabolic crosstalk between oral microbiota and the host in OSCC: emerging roles of microbial metabolites in tumor initiation and progression
10.3389/fcimb.2026.1778329 · 2026 · External reference
Jiawei danxuan koukang and its component kaempferol alleviate oral submucous fibrosis by restoring epithelial-fibroblast homeostasis and suppressing neutrophil recruitment via the ANXA1/FPR2 axis
10.1002/fsn3.71785 · 2026 · External reference
Abnormal collagen deposition mediated by cartilage oligomeric matrix protein in the pathogenesis of oral submucous fibrosis
10.1038/s41368-025-00355-x · 2025 · External reference
Hsa_circ_0060927 is a novel tumor biomarker by sponging miR-195-5p in the malignant transformation of OLK to OSCC
10.3389/fonc.2021.747086 · 2021 · External reference
Adipose-derived stem cell exosomes attenuates myofibroblast transformation via inhibiting autophagy through TGF-β/Smad2 axis in oral submucosal fibrosis
10.1186/s12951-024-03067-2 · External reference
The mechanism of low molecular weight fucoidan-incorporated nanofiber scaffolds inhibiting oral leukoplakia via SR-A/Wnt signal axis
10.3389/fphar.2024.1397761 · External reference
Host-guest assembly of transmucosal molecular spherical nucleic acids for oral leukoplakia immunotherapy and microbiota homeostasis restoration
10.1021/jacsau.6c00012 · 2026 · External reference
Podoplanin and ABCG2 expression in oral erythroplakia revisited: potential evidence for cancer stem cells driving the process of field cancerization
10.1016/j.oraloncology.2019.07.011 · 2020 · External reference
Stromal thrombospondin 1 suppresses angiogenesis in oral submucous fibrosis
10.1038/s41368-024-00286-z · External reference
Cucurbitacin B induces ferroptosis in oral leukoplakia via the SLC7A11/mitochondrial oxidative stress pathway
10.1016/j.phymed.2024.155548 · External reference
Humoral immune activation within tertiary lymphoid structures is correlated with poor outcomes in oral Lichen planus and lichenoid lesions
10.3389/fimmu.2025.1667976 · 2025 · External reference
Elucidating the role of lipid metabolism dysregulation in the transition from oral lichen planus to oral squamous cell carcinoma
10.1186/s12967-025-06431-4 · 2025 · External reference
Dysbiosis of the gut microbiome may contribute to the pathogenesis of oral Lichen planus through treg dysregulation
10.1016/j.mucimm.2025.05.009 · 2025 · External reference
Exploring possible diagnostic precancerous biomarkers for oral submucous fibrosis: a narrative review
10.3390/cancers15194812 · 2023 · External reference
Spatial proteomics reveals layer-specific molecular landscapes and keratin 17-mediated inflammatory crosstalk in oral Lichen planus of the tongue
10.1093/bjd/ljag040 · 2026 · External reference
Nomogram for risk prediction of malignant transformation in oral leukoplakia patients using combined biomarkers
10.1016/j.oraloncology.2017.07.015 · 2017 · External reference
Different expression profiles of circulating miR-31 and miR-181a in CD4+ T cells and plasma of patients with oral lichen planus
10.1016/j.intimp.2023.110306 · External reference
Photodynamic therapy (PDT) for oral leukoplakia: a systematic review and meta-analysis of single-arm studies examining efficacy and subgroup analyses
10.1186/s12903-023-03294-3 · External reference
Single-cell RNA sequencing highlights the immunosuppression of IDO1+ macrophages in the malignant transformation of oral leukoplakia
10.7150/thno.99112 · External reference
Clinical, histopathological characteristics and malignant transformation of proliferative verrucous leukoplakia with 36 patients: a retrospective longitudinal study
10.1186/s12903-024-04360-0 · External reference
Function of unconventional T cells in oral lichen planus revealed by single-cell RNA sequencing
10.1007/s00011-024-01912-6 · 2024 · External reference
Keratinocytes regulate intraepithelial lymphocytes homing and mediate mucosal barrier integrity via JAK2/STAT3 signaling in oral lichen planus
10.3389/fimmu.2026.1794867 · 2026 · External reference
Cigarette smoke promotes oral leukoplakia via regulating glutamine metabolism and M2 polarization of macrophage
10.1038/s41368-021-00128-2 · 2021 · External reference
Treatment of oral erosive Lichen planus with upadacitinib
10.1001/jamadermatol.2022.0147 · ExternalCitation · doi-reference
Oral acitretin plus topical triamcinolone vs topical triamcinolone monotherapy in patients with symptomatic oral lichen planus: a randomized clinical trial
10.1001/jamadermatol.2023.4889 · ExternalCitation · doi-reference
Cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life years for 29 cancer groups from 2010 to 2019: a systematic analysis for the global burden of disease study 2019
10.1001/jamaoncol.2021.6987 · ExternalCitation · doi-reference
Nivolumab for patients with high-risk oral leukoplakia: a nonrandomized controlled trial
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