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References from Serum uric acid in pediatric metabolic assessment: the scientific rationale for routine screening and the urgent need for age- and sex-specific diagnostic thresholds. Local targets link to admitted publications; unresolved targets remain external evidence.
Uric acid and cardiovascular risk
10.1056/nejmra0800885 · 2008 · External reference
Hyperuricemia and progression of CKD in children and adolescents: The chronic kidney disease in children (CKiD) cohort study
10.1053/j.ajkd.2015.06.015 · 2015 · External reference
Dietary fructose: from uric acid to a metabolic switch in pediatric metabolic dysfunction-associated steatotic liver disease
10.1080/10408398.2024.2392150 · 2025 · External reference
Unresolved reference
External reference
Prevalence and related factors of hyperuricaemia in Chinese children and adolescents: a pooled analysis of 11 population-based studies
10.1080/07853890.2022.2083670 · 2022 · External reference
Uric acid levels in overweight and obese children, and their correlation with metabolic risk factors
10.7759/cureus.70160 · 2024 · External reference
Age and gender-specific reference intervals for uric acid level in children aged 5–14 years in Southeast Zhejiang Province of China: Hyperuricemia in children may need redefinition
10.3389/fped.2021.560720 · 2021 · External reference
Reference interval of serum uric acid among healthy children and adolescents in Nanjing, China, and influencing factors
10.1080/07853890.2025.2531249 · 2025 · External reference
Pediatrics hyperuricemia in clinical practice: A retrospective analysis in 1753 children and adolescents with hyperuricemia
10.1016/j.jbspin.2024.105796 · 2025 · External reference
Changes in serum urate and urate excretion with age
10.1053/j.ackd.2012.07.010 · 2012 · External reference
Fructose and uric acid: Major mediators of cardiovascular disease risk starting at pediatric age
10.3390/ijms21124479 · 2020 · External reference
Genetic background of selected hyperuricemia causing gout with pediatric onset
10.1016/j.jbspin.2025.105884 · 2025 · External reference
The impact of dysfunctional variants of ABCG2 on hyperuricemia and gout in pediatric-onset patients
10.1186/s13075-019-1860-8 · 2019 · External reference
Serum concentrations of uric acid and the metabolic syndrome among US children and adolescents
10.1161/circulationaha.106.657627 · 2007 · External reference
Association of serum uric acid concentration with components of pediatric metabolic syndrome: A systematic review and meta-analysis
10.4103/jrms.jrms_733_19 · 2020 · External reference
Association between serum uric acid and metabolic syndrome components in prepubertal obese children (Tanner Stage I) from Nuevo León, Mexico - a preliminary study
10.1186/s40608-017-0160-6 · 2017 · External reference
Uric acid reference values: report on 1750 healthy Brazilian children and adolescents
10.1038/s41390-020-01185-9 · 2021 · External reference
Elevated uric acid levels link to a higher cardiometabolic risk profile in adolescents
10.1007/s40618-025-02798-9 · 2026 · External reference
Childhood uric acid predicts adult blood pressure
10.1161/01.hyp.0000150783.79172.bb · 2005 · External reference
Association between serum levels of uric acid and blood pressure tracking in childhood
10.1093/ajh/hpx037 · 2017 · External reference
Uric acid and arterial stiffness in children and adolescents: Role of insulin resistance and blood pressure
10.3389/fcvm.2022.978366 · 2022 · External reference
Effect of allopurinol on blood pressure of adolescents with newly diagnosed essential hypertension: a randomized trial
10.1001/jama.300.8.924 · 2008 · External reference
Uric acid reduction rectifies prehypertension in obese adolescents
10.1161/hypertensionaha.112.196980 · 2012 · External reference
Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism
10.1152/ajprenal.00283.2001 · 2002 · External reference
Factors influencing serum uric acid levels and their impact on cardiovascular risk in patients with pediatric chronic kidney disease
10.1007/s00467-025-06961-5 · 2026 · External reference
The Canadian laboratory initiative on pediatric reference intervals: A CALIPER white paper
10.1080/10408363.2017.1379945 · 2017 · External reference
Childhood and adolescent obesity: A review
10.3389/fped.2020.581461 · 2021 · External reference
Obesity: Prevalence, causes, consequences, management, preventive strategies and future research directions
10.1016/j.metop.2025.100375 · 2025 · External reference
Clinical practice consensus statement 2025: Management of hyperuricemia and gout in adolescents
10.1111/1756-185x.70378 · 2025 · External reference
Expert consensus for the diagnosis and treatment of patients with hyperuricemia and high cardiovascular risk: 2025 update
10.1016/j.ejim.2026.106727 · 2026 · External reference
Hyperuricemia and its related diseases: mechanisms and advances in therapy
10.1038/s41392-024-01916-y · 2024 · External reference
