References

Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021

10.1016/s0140-6736(24)00476-8 · 2024 · External reference

Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the global burden of disease study 2019

10.1016/s1474-4422(21)00252-0 · 2021 · External reference

Stroke mimics: incidence, aetiology, clinical features and treatment

10.1080/07853890.2021.1890205 · 2021 · External reference

Neuroimaging modalities used for ischemic stroke diagnosis and monitoring

10.3390/medicina59111908 · 2023 · External reference

Overview of imaging modalities in stroke

10.1212/wnl.0000000000012794 · 2021 · External reference

The role of amino acid metabolism alterations in acute ischemic stroke: from mechanism to application

10.1016/j.phrs.2024.107313 · 2024 · External reference

Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence

10.3389/fneur.2025.1630390 · 2025 · External reference

Analysis of metabolite and lipid association networks reveals molecular mechanisms associated with 3-month mortality and poor functional outcomes in patients with acute ischemic stroke after thrombolytic treatment with recombinant tissue plasminogen activator

2021 · External reference

Crosstalk between Nrf2 signaling pathway and inflammation in ischemic stroke: mechanisms of action and therapeutic implications

10.1016/j.expneurol.2023.114655 · 2024 · External reference

Tryptophan metabolism, inflammation, and oxidative stress in patients with neurovascular disease

10.3390/metabo10050208 · 2020 · External reference

Evaluation of stroke care delivery: 12-month experience of a tertiary stroke center in Central Asia

10.1155/ijcp/8109173 · 2025 · External reference

Metabolite signatures of chronological age, aging, survival, and longevity

10.1016/j.celrep.2024.114913 · 2024 · External reference

Prospective association between plasma amino acids and healthy aging in older adults

10.1111/joim.20105 · 2025 · External reference

The aging process: a metabolomics perspective

10.3390/molecules27248656 · 2022 · External reference

Sex differences in stroke: challenges and opportunities

10.1177/0271678x18793324 · 2018 · External reference

Heart disease and stroke statistics-2017 update: a report from the American Heart Association

2017 · External reference

A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance

10.1038/nm.4057 · 2016 · External reference

Insulin resistance is associated with altered amino acid metabolism and adipose tissue dysfunction in normoglycemic women

10.1038/srep24540 · 2016 · External reference

Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study

10.1016/s0140-6736(16)30506-2 · 2016 · External reference

World stroke organization: global stroke fact sheet 2025

10.1177/17474930241308142 · 2025 · External reference

Endothelial dysfunction in hypertension: current concepts and clinical implications

10.3389/fmed.2021.798958 · 2021 · External reference

Oxidative stress, antioxidants and hypertension

10.3390/antiox12020281 · 2023 · External reference

Tissue is the issue: a systematic review of methods for the determination of infarct volume in acute ischaemic stroke

2025 · External reference

Global epidemiology of stroke and access to acute ischemic stroke interventions

10.1212/wnl.0000000000012781 · 2021 · External reference

Limitations and blind spots of diffusion-weighted imaging in the evaluation of acute brain ischemia: a narrative review

10.3390/jcm15020885 · 2026 · External reference

Targeting neutrophils in ischemic stroke: translational insights from experimental studies

10.1038/jcbfm.2015.45 · 2015 · External reference

Neuroinflammation: friend and foe for ischemic stroke

10.1186/s12974-019-1516-2 · 2019 · External reference

Systemic immune responses after ischemic stroke: from the center to the periphery

10.3389/fimmu.2022.911661 · 2022 · External reference

Prognostic role of neutrophil-lymphocyte ratio in patients with acute ischemic stroke

10.1097/md.0000000000008624 · 2017 · External reference

Neutrophil-to-lymphocyte ratio predicts 3-month outcome of acute ischemic stroke

10.1007/s12640-017-9707-z · 2017 · External reference

Revisiting the mechanisms of CNS immune privilege

10.1016/j.it.2015.08.006 · 2015 · External reference

Neuroinflammation and peripheral immunity: focus on ischemic stroke

10.1016/j.intimp.2023.110332 · 2023 · External reference

Thrombo-inflammation and immunological response in ischemic stroke: focusing on platelet-Tregs interaction

10.3389/fncel.2022.955385 · 2022 · External reference

Fasting blood glucose as a predictor of progressive infarction in men with acute ischemic stroke

10.1177/03000605221132416 · 2022 · External reference

Stroke

10.1016/s0140-6736(20)31179-x · 2020 · External reference

Difference in acute and chronic stage ischemic stroke metabolic markers with controls

10.1016/j.jstrokecerebrovasdis.2023.107211 · 2023 · External reference

Izmenenie spektra svobodnykh aminokislot syvorotki krovi u bolnykh s tserebrovaskulyarnymi zabolevaniyami

2007 · External reference

Elevated plasma phenylalanine predicts mortality in critical patients with heart failure

10.1002/ehf2.12896 · 2020 · External reference

Inducible nitric oxide synthase: regulation, structure, and inhibition

10.1002/med.21599 · 2020 · External reference

An overview of NO signaling pathways in aging

10.3390/molecules26154533 · 2021 · External reference

Targeted metabolomic profiling reveals association between altered amino acids and poor functional recovery after stroke

10.3389/fneur.2019.01425 · 2019 · External reference

Platelet, plasma, urinary tryptophan-serotonin-kynurenine axis markers in hyperacute brain ischemia patients: a prospective study

10.3389/fneur.2021.782317 · 2021 · External reference

Systematic review on the involvement of the kynurenine pathway in stroke: pre-clinical and clinical evidence

10.3389/fneur.2019.00778 · 2019 · External reference

Sex differences in tryptophan metabolism via the kynurenine pathway in acute ischemic stroke

10.1016/j.clinthera.2024.10.015 · 2024 · External reference

Tryptophan metabolism and ischemic stroke: an intricate balance

10.4103/nrr.nrr-d-24-00777 · 2026 · External reference

Circulating metabolites differentiate acute ischemic stroke from stroke mimics

10.1002/ana.25859 · 2020 · External reference

Targeted metabolomics reveals serum changes of amino acids in mild to moderate ischemic stroke and stroke mimics

10.3389/fneur.2023.1153193 · 2023 · External reference

Immune responses to stroke: mechanisms, modulation, and therapeutic potential

10.1172/jci135530 · 2020 · External reference

Review of perfusion imaging in acute ischemic stroke: from time to tissue

10.1161/strokeaha.119.028337 · 2020 · External reference

Diffusion and perfusion MR imaging in acute stroke: clinical utility and potential limitations for treatment selection

10.1097/rmr.0000000000000124 · 2017 · External reference

What is the best imaging strategy for acute stroke?

10.3310/hta8010 · 2004 · External reference

Association between serum total bilirubin levels and 28-day all-cause mortality after intracerebral hemorrhage

10.3389/fneur.2025.1529415 · 2025 · External reference