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References from Human P301L tau expression in mice alters neuronal excitability independent of neurodegeneration. Local targets link to admitted publications; unresolved targets remain external evidence.
The role of neuroinflammation in neurodegenerative diseases: current understanding and future therapeutic targets
10.3389/fnagi.2024.1347987 · 2024 · External reference
Structure and novel exons of the human tau gene
10.1021/bi00158a027 · 1992 · External reference
Tau and tauopathies
10.1016/j.brainresbull.2016.08.018 · 2016 · External reference
Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease
10.1007/s004010100423 · 2002 · External reference
10.1007/978-1-0716-3545-2_4
10.1007/978-1-0716-3545-2_4 · 2024 · External reference
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
10.1038/nrn2194 · 2007 · External reference
Relative incidence of seizures and myoclonus in Alzheimer’s disease, dementia with Lewy bodies, and frontotemporal dementia
10.3233/jad-170031 · 2017 · External reference
The Miami framework for ALS and related neurodegenerative disorders: an integrated view of phenotype and biology
10.1038/s41582-024-00961-z · 2024 · External reference
Conceptual framework for the definition of preclinical and prodromal frontotemporal dementia
10.1002/alz.12485 · 2022 · External reference
Improved long-term potentiation and memory in young tau-P301L transgenic mice before onset of hyperphosphorylation and tauopathy
10.1523/jneurosci.5425-05.2006 · 2006 · External reference
A vector for expressing foreign genes in the brains and hearts of transgenic mice
10.1016/s1050-3862(96)00167-2 · 1996 · External reference
Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
10.1007/s00401-006-0127-z · 2006 · External reference
Staging of Alzheimer's disease-related neurofibrillary changes
10.1016/0197-4580(95)00021-6 · 1995 · External reference
Steady state responses: electrophysiological assessment of sensory function in schizophrenia
10.1093/schbul/sbp091 · 2009 · External reference
Microglial signatures and their role in health and disease
10.1038/s41583-018-0057-5 · 2018 · External reference
Neuronal oscillations in cortical networks
10.1126/science.1099745 · 2004 · External reference
Systematic review on resting-state EEG for Alzheimer’s disease diagnosis and progression assessment
10.1155/2018/5174815 · 2018 · External reference
Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production
10.1038/360672a0 · 1992 · External reference
Emerging electroencephalographic biomarkers to improve preclinical to clinical translation in Alzheimer’s disease
10.3389/fnagi.2022.805063 · 2022 · External reference
Electrophysiological changes precede morphological changes to frontal cortical pyramidal neurons in the rTg4510 mouse model of progressive tauopathy
10.1007/s00401-012-1038-9 · 2012 · External reference
Disease-associated microglia: a universal immune sensor of neurodegeneration
10.1016/j.cell.2018.05.003 · 2018 · External reference
Preclinical Alzheimer's disease: definition, natural history, and diagnostic criteria
10.1016/j.jalz.2016.02.002 · 2016 · External reference
Hyperphosphorylated tau induces cortical Hypoexcitability in transgenic mouse models: a meta-analysis
10.31083/jin39192 · 2025 · External reference
Monoclonal antibody AT8 recognises tau protein phosphorylated AT both serine 202 and threonine 205
10.1016/0304-3940(95)11484-e · 1995 · External reference
A decade of tau transgenic animal models and beyond
10.1111/j.1750-3639.2007.00051.x · 2007 · External reference
A unique microglia type associated with restricting development of Alzheimer's disease
10.1016/j.cell.2017.05.018 · 2017 · External reference
Unresolved reference
2012 · External reference
Axonal disruption and aberrant localization of tau protein characterize the neuropil pathology of Alzheimer's disease
10.1002/ana.410220514 · 1987 · External reference
Genetic forms of tauopathies: inherited causes and implications of Alzheimer's disease-like TAU pathology in primary and secondary tauopathies
10.1007/s00415-024-12314-3 · 2024 · External reference
Twenty years of therapeutic development in tauopathy mouse models: a scoping review
10.1002/alz.70578 · 2025 · External reference
The primary structure and heterogeneity of tau protein from mouse brain
10.1126/science.3122323 · 1988 · External reference
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
10.1038/78078 · 2000 · External reference
Ultrastructural neuronal pathology in transgenic mice expressing mutant (P301L) human tau
10.1023/b:neur.0000021904.61387.95 · 2003 · External reference
The role of tau phosphorylation in the pathogenesis of Alzheimer's disease
10.2174/156720506779025279 · 2006 · External reference
Apparent behavioral benefits of tau overexpression in P301L tau transgenic mice
10.3233/jad-2008-15407 · 2008 · External reference
A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid
10.1038/ng0892-345 · 1992 · External reference
Cellular and pathological functions of tau
10.1038/s41580-024-00753-9 · 2024 · External reference
Unresolved reference
2019 · External reference
How neuroinflammation contributes to neurodegeneration
10.1126/science.aag2590 · 2016 · External reference
Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility
10.1046/j.1471-4159.2002.01241.x · 2002 · External reference
Biochemical distribution of tau protein in synaptosomal fraction of transgenic mice expressing human P301L tau
10.3389/fneur.2014.00026 · 2014 · External reference
Limitations of human tau-expressing mouse models and novel approaches of mouse modeling for tauopathy
10.3389/fnins.2023.1149761 · 2023 · External reference
Microglia emerge as central players in brain disease
10.1038/nm.4397 · 2017 · External reference
Etiology and clinical significance of network hyperexcitability in alzheimer’s disease: unanswered questions and next steps
10.3233/jad-220983 · 2023 · External reference
Tau-induced pathology in epilepsy and dementia: notions from patients and animal models
10.3390/ijms19041092 · 2018 · External reference
Tau suppression in a neurodegenerative mouse model improves memory function
10.1126/science.1113694 · 2005 · External reference
ENX-101, a GABAA receptor α2,3,5-selective positive allosteric modulator, displays antiseizure effects in rodent seizure and epilepsy models
10.1111/epi.18340 · 2025 · External reference
The 40-Hz auditory steady-state response: a selective biomarker for cortical NMDA function
10.1111/nyas.12739 · 2015 · External reference
Tau pathology and neurodegeneration
10.1016/s1474-4422(13)70090-5 · 2013 · External reference
Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17)
10.1007/s100489900084 · 2000 · External reference
Tau phosphorylation: physiological and pathological consequences
10.1016/j.bbadis.2004.06.017 · 2005 · External reference
Neuronal hyperexcitability in Alzheimer’s disease: what are the drivers behind this aberrant phenotype?
10.1038/s41398-022-02024-7 · 2022 · External reference
Changed conformation of mutant tau-P301L underlies the moribund tauopathy, absent in progressive, nonlethal axonopathy of tau-4R/2N transgenic mice
10.1074/jbc.m409876200 · 2005 · External reference
Tau in physiology and pathology
10.1038/nrn.2015.1 · 2016 · External reference
Tauopathies: new perspectives and challenges
10.1186/s13024-022-00533-z · 2022 · External reference
