Research graph
References from Iron-driven secondary injury after intracranial hemorrhage: mitochondrial dysfunction and ferroptosis. Local targets link to admitted publications; unresolved targets remain external evidence.
Melatonin enhances the mitochondrial functionality of brown adipose tissue in obese—diabetic rats
10.3390/antiox10091482 · 2021 · External reference
Intracranial hemorrhage segmentation and classification framework in computer tomography images using deep learning techniques
10.1038/s41598-025-01317-3 · 2025 · External reference
Cognitive and functional outcome after aneurysmal subarachnoid hemorrhage
10.1161/strokeaha.110.581975 · 2010 · External reference
Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism responsible for anti-apoptotic effects of melatonin
10.1096/fj.03-1031fje · 2004 · External reference
Unresolved reference
2019 · External reference
Navigating the complexities of intraventricular hemorrhage in preterm infants: an updated review
10.7759/cureus.38985 · 2023 · External reference
The subdural membrane: unraveling the pathophysiology and treatment of chronic subdural hematoma
10.3389/fsurg.2025.1694048 · 2025 · External reference
Oxyhemoglobin as the principal cause of cerebral vasospasm: a holistic view of its actions
10.1007/s003290050147 · 1999 · External reference
Long-term cognitive decline after subarachnoid Hemorrhage: pathophysiology, management, and future directions
10.1161/strokeaha.124.049969 · 2025 · External reference
Demographics and prevalent risk factors of chronic subdural haematoma: results of a large single-center cohort study
10.1007/s10143-004-0337-6 · 2004 · External reference
Intraventricular Hemorrhage in premature infants: mechanism of disease
10.1203/pdr.0b013e3181c1b176 · 2010 · External reference
Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease
10.1038/s41418-020-00685-9 · 2021 · External reference
Secondary mechanisms of injury and viable pathophysiological targets in intracerebral hemorrhage
10.1177/17562864211049208 · 2021 · External reference
Iron Hemostasis in patients with subarachnoid Hemorrhage and the role of early CSF drainage
10.1212/wnl.0000000000213767 · 2025 · External reference
Increase in brain atrophy after subdural hematoma to rates greater than associated with dementia
10.3171/2017.8.jns17477 · 2018 · External reference
Oligodendrocytes: biology and pathology
10.1007/s00401-009-0601-5 · 2010 · External reference
Pyroptosis: molecular mechanisms and roles in disease
10.1038/s41422-025-01107-6 · 2025 · External reference
12/15-lipoxygenase inhibition attenuates neuroinflammation by suppressing inflammasomes
10.3389/fncel.2023.1277268 · 2023 · External reference
Improving mitochondrial function with SS-31 reverses age-related redox stress and improves exercise tolerance in aged mice
10.1016/j.freeradbiomed.2018.12.031 · 2019 · External reference
Selective ferroptosis inhibitor liproxstatin-1 attenuates neurological deficits and neuroinflammation after subarachnoid hemorrhage
10.1007/s12264-020-00620-5 · 2021 · External reference
Restoring system xc- activity by xCT overexpression inhibited neuronal ferroptosis and improved neurological deficits after experimental subarachnoid hemorrhage
10.1016/j.brainres.2023.148556 · 2023 · External reference
Baicalin attenuates global cerebral ischemia/reperfusion injury in gerbils via anti-oxidative and anti-apoptotic pathways
10.1016/j.brainresbull.2011.05.002 · 2011 · External reference
AMPK-PINK1/Parkin mediated mitophagy is necessary for alleviating oxidative stress-induced intestinal epithelial barrier damage and mitochondrial energy metabolism dysfunction in IPEC-J2
10.3390/antiox10122010 · 2021 · External reference
Continuous irrigation with thrombolytics for intraventricular Hemorrhage: case-control study
10.1007/s10143-023-02270-3 · 2024 · External reference
Mitochondria: novel mechanisms and therapeutic targets for secondary brain injury after intracerebral hemorrhage
10.3389/fnagi.2020.615451 · 2021 · External reference
Overexpression of ferroptosis defense enzyme Gpx4 retards motor neuron disease of SOD1G93A mice
10.1038/s41598-021-92369-8 · 2021 · External reference
Mitophagy in intracerebral Hemorrhage: a New target for therapeutic intervention
10.4103/1673-5374.379019 · 2024 · External reference
Netrin-1 alleviates early brain injury by regulating ferroptosis via the PPARγ/Nrf2/GPX4 Signaling pathway following subarachnoid hemorrhage
10.1007/s12975-022-01122-4 · 2024 · External reference
Identification of CSPG4 as a biomarker and therapeutic target for infantile post-Hemorrhagic hydrocephalus via multi-omics analysis
10.1002/advs.202410056 · 2025 · External reference
New targets in spontaneous intracerebral hemorrhage
10.1097/wco.0000000000001325 · 2025 · External reference
ROS-mediated mitophagy and apoptosis are involved in aluminum-induced femoral impairment in mice
10.1016/j.cbi.2021.109663 · 2021 · External reference
The involvement of Iron in traumatic brain injury and neurodegenerative disease
10.3389/fnins.2018.00981 · 2018 · External reference
APE1 regulates mitochondrial DNA damage repair after experimental subarachnoid haemorrhage in vivo and in vitro
10.1136/svn-2023-002524 · 2024 · External reference
Loss of TGFβ-mediated repression of angiopoietin-2 in pericytes underlies germinal matrix hemorrhage pathogenesis
10.1161/strokeaha.123.045248 · 2024 · External reference
The mechanism of ferroptosis in early brain injury after subarachnoid hemorrhage
10.3389/fimmu.2023.1191826 · 2023 · External reference
Ferroptosis: an iron-dependent form of nonapoptotic cell death
10.1016/j.cell.2012.03.042 · 2012 · External reference
Ferroptosis inhibitors: mechanisms of action and therapeutic potential
10.1007/s00018-025-05958-5 · 2025 · External reference
Pathophysiology of chronic subdural haematoma: inflammation, angiogenesis and implications for pharmacotherapy
10.1186/s12974-017-0881-y · 2017 · External reference
Delayed cerebral ischemia and therapeutic approaches after subarachnoid hemorrhage
10.37349/ent.2022.00026 · 2022 · External reference
Liproxstatin-1 is an effective inhibitor of oligodendrocyte ferroptosis induced by inhibition of glutathione peroxidase 4
10.4103/1673-5374.293157 · 2020 · External reference
Inhibiting ferroptosis through disrupting the NCOA4–FTH1 interaction: a new mechanism of action
10.1021/acscentsci.0c01592 · 2021 · External reference
Ferroptosis in brain microvascular endothelial cells mediates blood-brain barrier disruption after traumatic brain injury
10.1016/j.bbrc.2022.06.040 · 2022 · External reference
Targeting the microbiome-NLRP3-ferroptosis Axis in multiple sclerosis: neuropharmacological implications for microglial dysfunction and demyelination
10.1016/j.neuropharm.2026.111042 · 2026 · External reference
Lipocalin-2 inhibition alleviates neural injury by microglia ferroptosis suppression after experimental intracerebral hemorrhage in mice via enhancing ferritin light chain expression
10.1016/j.bbadis.2024.167435 · 2024 · External reference
The mechanism of ferroptosis and its related diseases
10.1186/s43556-023-00142-2 · 2023 · External reference
Effect of deferoxamine on trajectory of recovery after intracerebral hemorrhage: a post hoc analysis of the i-DEF trial
10.1161/strokeaha.121.037298 · 2022 · External reference
Minocycline in acute cerebral Hemorrhage: an early phase randomized trial
10.1161/strokeaha.117.018658 · 2017 · External reference
Management of delayed cerebral ischemia after subarachnoid hemorrhage
10.1186/s13054-016-1447-6 · 2016 · External reference
Hemolysis derived products toxicity and endothelium: model of the second hit
10.3390/toxins11110660 · 2019 · External reference
White matter injury after intracerebral Hemorrhage
10.3389/fneur.2021.562090 · 2021 · External reference
Early brain injury, an evolving frontier in subarachnoid Hemorrhage research
10.1007/s12975-013-0257-2 · 2013 · External reference
Cellular iron: Ferroportin is the only way out
10.1016/j.cmet.2005.02.005 · 2005 · External reference
Neuroprotective role of glutathione peroxidase 4 in experimental subarachnoid hemorrhage models
10.1016/j.lfs.2020.118050 · 2020 · External reference
Anti-HMGB1 mAb therapy reduces epidural hematoma injury
10.3390/ijms25115889 · 2024 · External reference
Brain Iron overload following intracranial haemorrhage
10.1136/svn-2016-000042 · 2016 · External reference
Iron metabolism and ferroptosis in early brain injury after subarachnoid haemorrhage
10.1007/s12035-024-04218-0 · 2024 · External reference
Unresolved reference
2019 · External reference
Role of mass effect on neuronal iron deposition after intracerebral hemorrhage
10.1016/j.expneurol.2023.114475 · 2023 · External reference
Curcumin pretreatment induces Nrf2 and an antioxidant response and prevents hemin-induced toxicity in primary cultures of cerebellar granule neurons of rats
10.1155/2013/801418 · 2013 · External reference
Preventive effects of lactoferrin on acute alcohol-induced liver injury via iron chelation and regulation of Iron metabolism
10.3168/jds.2023-24490 · 2024 · External reference
Treatment of intraventricular hemorrhage with external ventricular drainage and fibrinolysis: a comprehensive systematic review and Meta-analysis of complications and outcome
10.1016/j.wneu.2023.01.021 · 2023 · External reference
Thrombolytic removal of intraventricular haemorrhage in treatment of severe stroke: results of the randomised, multicentre, multiregion, placebo-controlled CLEAR III trial
10.1016/s0140-6736(16)32410-2 · 2017 · External reference
Early brain injury after aneurysmal subarachnoid hemorrhage: a multimodal neuromonitoring study
10.1186/s13054-015-0809-9 · 2015 · External reference
Oxidative stress and endothelial dysfunction: clinical evidence and therapeutic implications
10.1016/j.tcm.2013.12.001 · 2014 · External reference
Ginsenoside Rd enhances blood-brain barrier integrity after cerebral ischemia/reperfusion by alleviating endothelial cells ferroptosis via activation of NRG1/ErbB4-mediated PI3K/Akt/mTOR signaling pathway
10.1016/j.neuropharm.2024.109929 · 2024 · External reference
Morphological and functional alterations in the adenohypophysis in cases of brain death
2009 · External reference
Bedside diagnosis of mitochondrial dysfunction in aneurysmal subarachnoid hemorrhage
10.1111/ane.12258 · 2014 · External reference
Driving factors of neuronal ferroptosis
10.1016/j.tcb.2024.01.010 · 2024 · External reference
Iron induces blood-brain barrier alteration contributing to cognitive impairment in β-thalassaemia mice
10.1038/s41598-024-84395-z · 2025 · External reference
Deferoxamine ameliorates neurological dysfunction by inhibiting ferroptosis and neuroinflammation after traumatic brain injury
10.1016/j.brainres.2023.148383 · 2023 · External reference
Iron metabolism mediates microglia susceptibility in ferroptosis
10.3389/fncel.2022.995084 · 2022 · External reference
Neuroinflammation and iron metabolism after intracerebral hemorrhage: a glial cell perspective
10.3389/fneur.2024.1510039 · 2025 · External reference
Ferroptosis contributes to neuronal death and functional outcome after traumatic brain injury
10.1097/ccm.0000000000003555 · 2019 · External reference
Unresolved reference
2025 · External reference
Immunometabolic profiling of chronic subdural hematoma through untargeted mass spectrometry analysis: preliminary findings of a novel approach
10.3390/diagnostics13213345 · 2023 · External reference
The “neuro-glial-vascular” unit: the role of glia in neurovascular unit formation and dysfunction
10.3389/fcell.2021.732820 · 2021 · External reference
Hemoglobin and Iron handling in brain after subarachnoid Hemorrhage and the effect of deferoxamine on early brain injury
10.1038/jcbfm.2010.137 · 2010 · External reference
Ferroptosis: past, present and future
10.1038/s41419-020-2298-2 · 2020 · External reference
Inhibition of neuronal ferroptosis protects hemorrhagic brain
10.1172/jci.insight.90777 · 2017 · External reference
Hepcidin treatment modulates the expression of divalent metal transporter-1, ceruloplasmin, and ferroportin-1 in the rat cerebral cortex and hippocampus
10.1007/s12011-011-8967-3 · 2011 · External reference
Β-amyloid protein induces mitophagy-dependent ferroptosis through the CD36/PINK/PARKIN pathway leading to blood–brain barrier destruction in Alzheimer’s disease
10.1186/s13578-022-00807-5 · 2022 · External reference
Iron neurotoxicity and protection by deferoxamine in intracerebral hemorrhage
10.3389/fnmol.2022.927334 · 2022 · External reference
Inhibition of ferroptosis alleviates early brain injury after subarachnoid Hemorrhage in vitro and in vivo via reduction of lipid peroxidation
10.1007/s10571-020-00850-1 · 2021 · External reference
Effects of deferoxamine on blood-brain barrier disruption after subarachnoid hemorrhage
10.1371/journal.pone.0172784 · 2017 · External reference
Ferroptosis participates in neuron damage in experimental cerebral malaria and is partially induced by activated CD8+ T cells
10.1186/s13041-022-00942-7 · 2022 · External reference
Deferoxamine reduces endothelial ferroptosis and protects cerebrovascular function after experimental traumatic brain injury
10.1016/j.brainresbull.2024.110878 · 2024 · External reference
Microglial ferroptotic stress causes non-cell autonomous neuronal death
10.1186/s13024-023-00691-8 · 2024 · External reference
Ferroptosis: an emerging therapeutic target in stroke
10.1111/jnc.15351 · 2022 · External reference
Elamipretide (SS-31) improves functional connectivity in hippocampus and other related regions following prolonged neuroinflammation induced by lipopolysaccharide in aged rats
10.3389/fnagi.2021.600484 · 2021 · External reference
Ferroptosis of brain microvascular endothelial cells contributes to hypoxia-induced blood–brain barrier injury
10.1096/fj.202201765r · 2023 · External reference
THBS1 in macrophage-derived exosomes exacerbates cerebral ischemia–reperfusion injury by inducing ferroptosis in endothelial cells
10.1186/s12974-025-03382-x · 2025 · External reference
Heme oxygenase-1: the roles of both good and evil in neurodegenerative diseases
10.1111/jnc.15969 · 2023 · External reference
Autophagy: regulator of cell death
10.1038/s41419-023-06154-8 · 2023 · External reference
Endothelial ferroptosis in blood–brain barrier dysfunction and neuroinflammation: mechanisms and immune–vascular crosstalk
10.3389/fimmu.2026.1825000 · 2026 · External reference
Intracranial hemorrhage – mechanisms of secondary brain injury
10.1007/978-3-7091-0693-8_11 · 2011 · External reference
Didang Tang alleviates neuronal ferroptosis after intracerebral hemorrhage by modulating the PERK/eIF2α/ATF4/CHOP/GPX4 signaling pathway
10.3389/fphar.2024.1472813 · 2024 · External reference
Cerebral hemorrhage: pathophysiology, treatment, and future directions
10.1161/circresaha.121.319949 · 2022 · External reference
Quantitative proteomics identifies NCOA4 as the cargo receptor mediating Ferritinophagy
10.1038/nature13148 · 2014 · External reference
Research progress on ferroptosis in cerebral hemorrhage
10.1016/j.biopha.2025.117932 · 2025 · External reference
The induction of ferroptosis in posthemorrhagic hydrocephalus
10.1016/j.brainres.2022.148133 · 2023 · External reference
Activation of the hepcidin-ferroportin1 pathway in the brain and astrocytic–neuronal crosstalk to counteract iron dyshomeostasis during aging
10.1038/s41598-022-15812-4 · 2022 · External reference
Insight into the mechanism of ferroptosis inhibition by ferrostatin-1
10.1016/j.redox.2019.101328 · 2019 · External reference
Why should neuroscientists worry about Iron? The emerging role of ferroptosis in the pathophysiology of neuroprogressive diseases
10.1016/j.bbr.2017.12.036 · 2018 · External reference
Molecular mechanisms of cell death in neurological diseases
10.1038/s41418-021-00814-y · 2021 · External reference
The neuroprotective effect of diazoxide is mediated by mitochondrial ATP-dependent potassium channels in a rat model of acute subdural hematoma
10.1016/j.jocn.2012.03.027 · 2013 · External reference
Implications of Iron in ferroptosis, necroptosis, and pyroptosis as potential players in TBI morbidity and mortality
10.1080/17590914.2024.2394352 · 2024 · External reference
Biochemical indications of cerebral ischaemia and mitochondrial dysfunction in severe brain trauma analysed with regard to type of lesion
10.1007/s00701-016-2835-z · 2016 · External reference
Chronic subdural hematoma (cSDH): a review of the current state of the art
10.1016/j.bas.2021.100300 · 2021 · External reference
Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
10.1074/jbc.c200677200 · 2003 · External reference
Unresolved reference
2025 · External reference
Perspectives: understanding the pathophysiology of intraventricular Hemorrhage in preterm infants and considering of the future direction for treatment
10.3340/jkns.2023.0020 · 2023 · External reference
NOX4 promotes ferroptosis of astrocytes by oxidative stress-induced lipid peroxidation via the impairment of mitochondrial metabolism in Alzheimer’s diseases
10.1016/j.redox.2021.101947 · 2021 · External reference
Deferoxamine-modified hybrid materials for direct chelation of Fe(III) ions from aqueous solutions and indication of the competitiveness of in vitro complexing toward a biological system
10.1021/acsomega.1c01411 · 2021 · External reference
Neuron-targeted liposomal coenzyme Q10 attenuates neuronal ferroptosis after subarachnoid hemorrhage by activating the ferroptosis suppressor protein 1/coenzyme Q10 system
10.1016/j.actbio.2024.03.023 · 2024 · External reference
Ferroptosis in microglial activation: a systematic review and multidata comparison
10.1093/braincomms/fcag109 · 2026 · External reference
Unresolved reference
2025 · External reference
Nitrite infusions to prevent delayed cerebral vasospasm in a primate model of subarachnoid Hemorrhage
10.1001/jama.293.12.1477 · 2005 · External reference
Intracerebral haemorrhage
10.1038/s41572-023-00424-7 · 2023 · External reference
Insights into the potential pathogenesis and therapeutic implications of ferroptosis in brain microvascular endothelial cells during stroke
10.3389/fimmu.2026.1787418 · 2026 · External reference
Brain Edema after intracerebral hemorrhage in rats: the role of iron overload and aquaporin 4
10.3171/2008.4.jns17512 · 2009 · External reference
Anti-viral potential and modulation of Nrf2 by curcumin: pharmacological implications
10.3390/antiox9121228 · 2020 · External reference
Synergistic protective effects of mitochondrial division inhibitor 1 and mitochondria-targeted small peptide SS31 in Alzheimer’s disease
10.3233/jad-170988 · 2018 · External reference
Microglial ferroptosis mediated neuroinflammation in central nervous system diseases
10.1016/j.brainresbull.2026.112020 · 2026 · External reference
Ferroptosis in neurological diseases
10.3389/fncel.2020.00218 · 2020 · External reference
Modeling ferroptosis in human dopaminergic neurons: pitfalls and opportunities for neurodegeneration research
10.1016/j.redox.2024.103165 · 2024 · External reference
A review of cell death pathways in hemorrhagic stroke
10.3389/fcell.2025.1570569 · 2025 · External reference
Coenzyme Q10 phytosome formulation improves CoQ10 bioavailability and mitochondrial functionality in cultured cells
10.3390/antiox10060927 · 2021 · External reference
Mitochondrial dysfunction in glial cells: implications for neuronal homeostasis and survival
10.1016/j.tox.2017.06.011 · 2017 · External reference
Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration
10.1038/s41593-022-01221-3 · 2023 · External reference
Chronic subdural hematoma: a perspective on subdural membranes and dementia
10.1016/j.wneu.2017.09.063 · 2017 · External reference
Nanoparticle formulation and in vitro efficacy testing of the mitoNEET ligand NL-1 for drug delivery in a brain endothelial model of ischemic reperfusion-injury
10.1016/j.ijpharm.2020.119090 · 2020 · External reference
The significance of chondroitin Sulfate proteoglycan 4 (CSPG4) in human gliomas
10.3390/ijms19092724 · 2018 · External reference
Regulation of iron metabolism by hepcidin under conditions of inflammation
10.1074/jbc.r115.650150 · 2015 · External reference
Oxidative stress and new pathogenetic mechanisms in endothelial dysfunction: potential diagnostic biomarkers and therapeutic targets
10.3390/jcm9061995 · 2020 · External reference
Deferoxamine mesylate in patients with intracerebral haemorrhage (i-DEF): a multicentre, randomised, placebo-controlled, double-blind phase 2 trial
10.1016/s1474-4422(19)30069-9 · 2019 · External reference
Secondary brain injury by oxidative stress after cerebral hemorrhage: recent advances
10.3389/fncel.2022.853589 · 2022 · External reference
Inhibition of the mitochondrial fission protein dynamin-related protein 1 improves survival in a murine cardiac arrest model
10.1097/ccm.0000000000000817 · 2015 · External reference
The effects of orally administered lactoferrin in the prevention and Management of Viral Infections: a systematic review
10.1002/rmv.2261 · 2022 · External reference
Astaxanthin inhibits apoptosis in alveolar epithelial cells type II in vivo and in vitro through the ROS -dependent mitochondrial signalling pathway
10.1111/jcmm.12347 · 2014 · External reference
Local and systemic pro-inflammatory and anti-inflammatory cytokine patterns in patients with chronic subdural hematoma: a prospective study
10.1007/s00011-012-0476-0 · 2012 · External reference
Ferroptosis: a regulated cell death Nexus linking metabolism, redox biology, and disease
10.1016/j.cell.2017.09.021 · 2017 · External reference
Deferoxamine in intracerebral hemorrhage: systematic review and meta-analysis
10.1016/j.clineuro.2023.107634 · 2023 · External reference
Unresolved reference
2018 · External reference
Role of hepcidin and its downstream proteins in early brain injury after experimental subarachnoid hemorrhage in rats
10.1007/s11010-016-2730-1 · 2016 · External reference
The role of iron, its metabolism and ferroptosis in traumatic brain injury
10.3389/fncel.2020.590789 · 2020 · External reference
C3/C3aR inhibition alleviates GMH-IVH-induced hydrocephalus by preventing microglia-astrocyte interactions in neonatal rats
10.1016/j.neuropharm.2021.108927 · 2022 · External reference
Biomedicine meets Fenton chemistry
10.1021/acs.chemrev.0c00977 · 2021 · External reference
LUHMES dopaminergic neurons are uniquely susceptible to ferroptosis
10.1007/s12640-022-00538-y · 2022 · External reference
Ferroptosis inhibitor liproxstatin-1 alleviates metabolic dysfunction-associated fatty liver disease in mice: potential involvement of PANoptosis
10.1038/s41401-022-01010-5 · 2023 · External reference
Elamipretide: a review of its structure, mechanism of action, and therapeutic potential
10.3390/ijms26030944 · 2025 · External reference
The dual role of hepcidin in brain Iron load and inflammation
10.3389/fnins.2018.00740 · 2018 · External reference
Impaired cerebral mitochondrial function after traumatic brain injury in humans
10.3171/jns.2000.93.5.0815 · 2000 · External reference
Novel mitoNEET ligand NL-1 improves therapeutic outcomes in an aged rat model of cerebral ischemia/reperfusion injury
10.1016/j.expneurol.2022.114128 · 2022 · External reference
Effect of prenatal glucocorticoids on cerebral vasculature of the developing brain
10.1161/strokeaha.110.588400 · 2010 · External reference
Navigating challenges in hydrocephalus following intraventricular hemorrhage: a comprehensive review of current evidence
10.3389/fneur.2025.1630286 · 2025 · External reference
Ferroptosis-related genes participate in the microglia-induced neuroinflammation of spinal cord injury via NF-κB signaling: evidence from integrated single-cell and spatial transcriptomic analysis
10.1186/s12967-025-06095-0 · 2025 · External reference
Ferrostatin-1 attenuates brain injury in animal model of subarachnoid hemorrhage via phospholipase A2 activity of PRDX6
10.1097/wnr.0000000000001931 · 2023 · External reference
The role of Iron in brain ageing and neurodegenerative disorders
10.1016/s1474-4422(14)70117-6 · 2014 · External reference
Resolution of intraventricular Hemorrhage varies by ventricular region and dose of intraventricular thrombolytic: the CLEAR IVH program
10.1161/strokeaha.112.650523 · 2012 · External reference
Celastrol alleviates secondary brain injury following intracerebral haemorrhage by inhibiting neuronal ferroptosis and blocking blood-brain barrier disruption
10.1016/j.ibneur.2024.08.003 · 2024 · External reference
Mitochondrial dysfunction during hypoxia/reoxygenation and its correction by anaerobic metabolism of citric acid cycle intermediates
10.1073/pnas.97.6.2826 · 2000 · External reference
Brain iron homeostasis and mental disorders
10.3390/antiox12111997 · 2023 · External reference
The key role of the ferroptosis mechanism in neurological diseases and prospects for targeted therapy
10.3389/fnins.2025.1591417 · 2025 · External reference
Role of iron-related oxidative stress and mitochondrial dysfunction in cardiovascular diseases
10.1155/2022/5124553 · 2022 · External reference
Role of mitochondrial calcium uniporter in early brain injury after experimental subarachnoid Hemorrhage
10.1007/s12035-014-8942-z · 2015 · External reference
High dose deferoxamine in intracerebral Hemorrhage (hi-def) trial: rationale, design, and methods
10.1007/s12028-013-9861-y · 2013 · External reference
Effects of epidural compression on stellate neurons and thalamocortical afferent Fibers in the rat primary somatosensory cortex
10.21307/ane-2017-032 · 2017 · External reference
Astrocyte-derived hepcidin controls iron traffic at the blood-brain-barrier via regulating ferroportin 1 of microvascular endothelial cells
10.1038/s41419-022-05043-w · 2022 · External reference
A mechanism linking ferroptosis and ferritinophagy in melatonin-related improvement of diabetic brain injury
10.1016/j.isci.2024.109511 · 2024 · External reference
The clinical effect of deferoxamine mesylate on Edema after intracerebral hemorrhage
10.1371/journal.pone.0122371 · 2015 · External reference
Activation of SIRT1 alleviates ferroptosis in the early brain injury after subarachnoid hemorrhage
10.1155/2022/9069825 · 2022 · External reference
Single-cell sequencing analysis of chronic subdural hematoma cell subpopulations and their potential therapeutic mechanisms
10.1016/j.brainresbull.2024.110936 · 2024 · External reference
Hepcidin overexpression in astrocytes alters brain iron metabolism and protects against amyloid-β induced brain damage in mice
10.1038/s41420-020-00346-3 · 2020 · External reference
The effect of subarachnoid erythrocyte lysate on brain injury: a preliminary study
10.1042/bsr20160100 · 2016 · External reference
Primary intraventricular hemorrhage in adults: etiological causes and prognostic factors in Chinese population
10.1007/s00415-016-8367-x · 2017 · External reference
Oxidative stress following intracerebral hemorrhage: from molecular mechanisms to therapeutic targets
10.3389/fimmu.2022.847246 · 2022 · External reference
Iron/ROS/Itga3 mediated accelerated depletion of hippocampal neural stem cell Pool contributes to cognitive impairment after Hemorrhagic stroke
10.1016/j.redox.2024.103086 · 2024 · External reference
GPX4, ferroptosis, and diseases
10.1016/j.biopha.2024.116512 · 2024 · External reference
Inclisiran attenuates Alzheimer’s disease-like changes by suppressing microvascular endothelial ferroptosis to preserve blood-brain barrier integrity
10.1016/j.freeradbiomed.2026.01.045 · 2026 · External reference
Revisiting minocycline in intracerebral Hemorrhage: mechanisms and clinical translation
10.3389/fimmu.2022.844163 · 2022 · External reference
NL-1 promotes PINK1-Parkin-mediated mitophagy through MitoNEET inhibition in subarachnoid Hemorrhage
10.1007/s11064-023-04024-5 · 2024 · External reference
Iron and oxidizing species in oxidative stress and Alzheimer’s disease
10.1002/agm2.12074 · 2019 · External reference
Unresolved reference
2026 · External reference
The role of mitochondria in iron overload-induced damage
10.1186/s12967-024-05740-4 · 2024 · External reference
Targeting ferroptosis with natural products in stroke: therapeutic mechanisms and translational opportunities
10.3389/fphar.2025.1586345 · 2025 · External reference
Selenoprotein P expression in glioblastoma as a regulator of ferroptosis sensitivity: preservation of GPX4 via the cycling-selenium storage
10.1038/s41598-024-51259-5 · 2024 · External reference
Ferroptosis: mechanisms and therapeutic targets
10.1002/mco2.70010 · 2024 · External reference
SS31 confers cerebral protection by reversing mitochondrial dysfunction in early brain injury following subarachnoid hemorrhage, via the Nrf2- and PGC-1α-dependent pathways
10.1007/s11064-022-03850-3 · 2023 · External reference
Efficient iron and ROS nanoscavengers for brain protection after intracerebral hemorrhage
10.1021/acsami.1c00491 · 2021 · External reference
Cristae formation—linking ultrastructure and function of mitochondria
10.1016/j.bbamcr.2008.06.013 · 2009 · External reference
