Research graph
References from A mechanistically informed framework of hierarchical temporal speech organization for objective differential assessment of motor speech disorders in neurodegenerative diseases. Local targets link to admitted publications; unresolved targets remain external evidence.
Speech rate and rhythm in cerebellar dysarthria: an acoustic analysis of syllabic timing
10.1159/000266295 · 1994 · External reference
From clues to mechanisms: understanding ALS initiation and spread
10.1212/01.wnl.0000325992.50108.60 · 2008 · External reference
Responsible development of clinical speech AI: bridging the gap between clinical research and technology
10.1038/s41746-024-01199-1 · 2024 · External reference
Speech technology for automatic recognition and assessment of dysarthric speech: an overview
10.1044/2024_jslhr-23-00740 · 2025 · External reference
Unresolved reference
External reference
A systematic review and narrative analysis of digital speech biomarkers in motor neuron disease
10.1038/s41746-023-00959-9 · 2023 · External reference
Exploring the role of machine learning in diagnosing and treating speech disorders: a systematic literature review
10.2147/prbm.s460283 · 2024 · External reference
Spreading of pathology in neurodegenerative diseases: a focus on human studies
10.1038/nrn3887 · 2015 · External reference
The natural statistics of audiovisual speech
10.1371/journal.pcbi.1000436 · 2009 · External reference
Dysarthria and dysphagia in Amyotrophic Lateral Sclerosis with spinal onset: a study of quality of life related to swallowing
10.3233/nre-141200 · 2015 · External reference
Differential diagnostic patterns of dysarthria
10.1044/jshr.1202.246 · External reference
Clusters of deviant speech dimensions in the dysarthrias
10.1044/jshr.1203.462 · External reference
The impact of Parkinson's disease on breath pauses and their relationship to speech impairment: a longitudinal study
10.1044/2020_ajslp-20-00003 · 2020 · External reference
Hypoglossal, trigeminal, and facial motoneuron involvement in amyotrophic lateral sclerosis
10.1212/wnl.38.2.281 · 1988 · External reference
Profiles of dysarthria and dysphagia in individuals with amyotrophic lateral sclerosis
10.1044/2022_jslhr-22-00312 · 2023 · External reference
Temporal envelope and fine structure cues for speech intelligibility
10.1121/1.413112 · 1995 · External reference
Precision medicine in ALS: identification of new acoustic markers for dysarthria severity assessment
10.1016/j.bspc.2023.105706 · External reference
Voice signals database of ALS patients with different dysarthria severity and healthy controls
10.1038/s41597-024-03597-2 · External reference
Unresolved reference
2013 · External reference
Regularized discriminant analysis
10.1080/01621459.1989.10478752 · 1989 · External reference
Supporting communication for patients with neurodegenerative disease
10.3233/nre-151241 · 2015 · External reference
Cortical oscillations and speech processing: emerging computational principles and operations
10.1038/nn.3063 · 2012 · External reference
Additional evidence for a therapeutic effect of dextromethorphan/quinidine on bulbar motor function in patients with amyotrophic lateral sclerosis: a quantitative speech analysis
10.1111/bcp.13745 · 2018 · External reference
Algorithmic estimation of pauses in extended speech samples of dysarthric and typical speech
2004 · External reference
Speech and pause characteristics following speech rate reduction in hypokinetic dysarthria
10.1016/0021-9924(95)00037-2 · 1996 · External reference
Effect of Parkinson's disease on the production of structured and unstructured speaking tasks: respiratory physiologic and linguistic considerations
10.1044/1092-4388(2010/09-0184) · 2011 · External reference
Impact of typical aging and Parkinson's disease on the relationship among breath pausing, syntax, and punctuation
10.1044/1058-0360(2012/11-0059) · 2012 · External reference
Bridging AI innovation and healthcare: scalable clinical validation methods for voice biomarkers [perspective]
10.3389/fdgth.2025.1575753 · 2025 · External reference
Unresolved reference
External reference
Acoustic-emergent phonology in the amplitude envelope of child-directed speech
10.1371/journal.pone.0144411 · 2015 · External reference
The temporal modulation structure of infant-directed speech
10.1162/opmi_a_00008 · 2017 · External reference
Discriminating dysarthria type from envelope modulation spectra
10.1044/1092-4388(2010/09-0121) · 2010 · External reference
Crosslinguistic application of English-centric rhythm descriptors in motor speech disorders
10.1159/000350030 · 2013 · External reference
Quantifying speech rhythm abnormalities in the dysarthrias
10.1044/1092-4388(2009/08-0208) · 2009 · External reference
Ten Alzheimer's disease and mild cognitive impairment: a systematic review article
10.3389/fpsyg.2021.620251 · 2021 · External reference
Application of automated data analytics and machine learning to develop explainable objective markers for differential assessment of progressive motor speech disorders in neurodegenerative diseases
10.64187/ain.2026.v1.i3.001 · 2026 · External reference
Parkinson's disease-associated dysarthria: prevalence, impact and management strategies
10.2147/jprls.s168090 · 2019 · External reference
The montreal cognitive assessment, MoCA: a brief screening tool for mild cognitive impairment
10.1111/j.1532-5415.2005.53221.x · 2005 · External reference
A survey of technologies for automatic dysarthric speech recognition
10.1186/s13636-023-00318-2 · 2023 · External reference
Unresolved reference
External reference
Speech treatment for Parkinson's disease
10.1586/14737175.8.2.297 · 2008 · External reference
Interpretation of canonical discriminant functions, canonical variates, and principal components
10.1080/00031305.1992.10475889 · 1992 · External reference
Neural entrainment to speech modulates speech intelligibility
10.1016/j.cub.2017.11.033 · 2018 · External reference
Automated acoustic analysis of oral diadochokinesis to assess bulbar motor involvement in amyotrophic lateral sclerosis
10.1044/2019_jslhr-19-00178 · 2020 · External reference
Functional role of temporal patterning of articulation in speech production: a novel perspective toward global timing-based motor speech assessment and rehabilitation
10.1044/2022_jslhr-22-00089 · 2022 · External reference
Hierarchical temporal structuring of speech: a multiscale, multimodal framework to inform the assessment and management of neuromotor speech disorder
10.1044/2023_jslhr-23-00219 · 2024 · External reference
An interpretable, clinically grounded framework for digital speech biomarker development in neurodegenerative diseases [Original Research]
10.3389/fdgth.2026.1794169 · 2026 · External reference
An explanatory model of speech communication centered on multiscale rhythmic modulation: implications for motor speech assessment and intervention for individuals with amyotrophic lateral sclerosis
10.1044/2025_jslhr-24-00286 · 2025 · External reference
A fine-grained temporal analysis of multimodal oral diadochokinetic performance to assess speech impairment in amyotrophic lateral sclerosis
10.1044/2023_ajslp-23-00177 · 2024 · External reference
A vowel-centric view toward characterizing temporal organization of motor speech activities in neurologically impaired and healthy speakers
10.1044/2023_jslhr-23-00129 · 2023 · External reference
Predicting early bulbar decline in Amyotrophic Lateral Sclerosis: a speech subsystem approach
10.1155/2015/183027 · 2015 · External reference
Predicting speech intelligibility decline in amyotrophic lateral sclerosis based on the deterioration of individual speech subsystems
10.1371/journal.pone.0154971 · 2016 · External reference
From prodromal stages to clinical trials: The promise of digital speech biomarkers in Parkinson's disease
10.1016/j.neubiorev.2024.105922 · 2024 · External reference
SAND: the challenge on speech analysis for neurodegenerative disease assessment
10.1109/ojsp.2026.3713044 · 2026 · External reference
Computational strategies for multivariate linear mixed-effects models with missing values
10.1198/106186002760180608 · 2002 · External reference
Aspects of speech rate and regularity in Parkinson's disease
10.1016/j.jns.2011.07.020 · 2011 · External reference
Chimaeric sounds reveal dichotomies in auditory perception
10.1038/416087a · 2002 · External reference
Interactions of pathological proteins in neurodegenerative diseases
10.1007/s00401-017-1709-7 · 2017 · External reference
Consensus criteria for the diagnosis of frontotemporal cognitive and behavioural syndromes in amyotrophic lateral sclerosis
10.1080/17482960802654364 · 2009 · External reference
Speech and Swallowing in Parkinson's Disease
10.1097/01.tgr.0000318899.87690.44 · 2008 · External reference
Proteopathic strains and the heterogeneity of neurodegenerative diseases
10.1146/annurev-genet-120215-034943 · 2016 · External reference
Tongues and lips without jaws: a comparison of methods for decoupling speech movements
10.1044/1092-4388(2002/052) · 2002 · External reference
Unresolved reference
2007 · External reference
Speech deterioration in amyotrophic lateral sclerosis: Implications for the timing of intervention
1993 · External reference
Clinical measures of bulbar dysfunction in ALS
10.3389/fneur.2019.00106 · 2019 · External reference
Profiling speech and pausing in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)
10.1371/journal.pone.0147573 · 2016 · External reference
Speech timing in ataxic disorders: sentence production and rapid repetitive articulation
10.1212/wnl.47.1.208 · 1996 · External reference
Regularization and variable selection via the elastic net
10.1111/j.1467-9868.2005.00503.x · 2005 · External reference
