Research graph
References from The aryl hydrocarbon receptor is expressed in non-sensory cells in the cochlea and regulates hair cell survival. Local targets link to admitted publications; unresolved targets remain external evidence.
Functional hair cell mechanotransducer channels are required for aminoglycoside ototoxicity
10.1371/journal.pone.0022347 · 2011 · External reference
Sox2+ adult stem and progenitor cells are important for tissue regeneration and survival of mice
10.1016/j.stem.2011.09.001 · 2011 · External reference
Regulated reprogramming in the regeneration of sensory receptor cells
10.1016/j.neuron.2011.07.015 · 2011 · External reference
Noise-induced cochlear synaptopathy in C57BL/6 N mice as a function of trauma strength: ribbons are more vulnerable than postsynapses
10.3389/fncel.2024.1465216 · 2024 · External reference
Degeneration in the cochlea after noise damage: primary versus secondary events
2000 · External reference
Irreversible inner ear damage from rock music
1976 · External reference
Nrf2 and AhR in metabolic reprogramming after contaminant exposure
10.1016/j.cotox.2017.12.001 · 2018 · External reference
Exosomes mediate sensory hair cell protection in the inner ear
10.1172/jci128867 · 2020 · External reference
Cloning of the ah-receptor cDNA reveals a distinctive ligand-activated transcription factor
10.1073/pnas.89.17.8185 · 1992 · External reference
Characterization of the transcriptome of nascent hair cells and identification of direct targets of the Atoh1 transcription factor
10.1523/jneurosci.5083-14.2015 · 2015 · External reference
Critical role of ATP-induced ATP release for Ca2+ signaling in nonsensory cell networks of the developing cochlea
10.1073/pnas.1616061113 · 2016 · External reference
Activation of the NF κ B pathway enhances AhR expression in intestinal Caco-2 cells
10.1155/2013/792452 · 2013 · External reference
Intercellular signaling in glial cells: calcium waves and oscillations in response to mechanical stimulation and glutamate
10.1016/0896-6273(91)90238-u · 1991 · External reference
P2X7 receptor is required for the ototoxicity caused by aminoglycoside in developing cochlear hair cells
10.1016/j.nbd.2023.106176 · 2023 · External reference
Characterization of a unique cell population marked by transgene expression in the adult cochlea of nestin-CreERT2 /tdTomato-reporter mice
10.1002/cne.23747 · 2015 · External reference
The notch ligand Jagged1 is required for the formation, maintenance, and survival of Hensen’s cells in the mouse cochlea
10.1523/jneurosci.1192-20.2020 · 2020 · External reference
A protocol for cryoembedding the adult guinea pig cochlea for fluorescence immunohistology
10.1016/j.jneumeth.2008.09.007 · 2009 · External reference
Immunolocalization of the calcium binding S100A1, S100A5 and S100A6 proteins in the dog cochlea during postnatal development
10.1016/s0165-3806(00)00153-x · 2001 · External reference
The aryl hydrocarbon receptor: structure, signaling, physiology and pathology
10.1038/s41392-025-02500-8 · 2026 · External reference
Immediate early gene c-fos in the brain: focus on glial cells
10.3390/brainsci12060687 · 2022 · External reference
AhR deletion promotes aberrant morphogenesis and synaptic activity of adult-generated granule neurons and impairs hippocampus-dependent memory
10.1523/eneuro.0370-17.2018 · 2018 · External reference
And now for something completely different: diversity in ligand-dependent activation of ah receptor responses
10.1016/j.cotox.2017.01.006 · 2017 · External reference
Structural basis for the ligand-dependent activation of heterodimeric AHR-ARNT complex
10.1038/s41467-025-56574-7 · 2025 · External reference
Antioxidant functions of the aryl hydrocarbon receptor
10.1155/2016/7943495 · 2016 · External reference
Supporting cell involvement in cochlear damage and repair: novel insights from a quantitative analysis of cyclodextrin-induced ototoxicity in mice
10.1016/j.heares.2025.109201 · 2025 · External reference
The aryl hydrocarbon receptor contributes to tissue adaptation of intestinal eosinophils in mice
2022 · External reference
2,3,7,8-Tetrachlorodibenzo-p-dioxin receptors regulate transcription of the cytochrome P1-450 gene
10.1002/jcb.240350208 · 1987 · External reference
AHR and NRF2 in skin homeostasis and atopic dermatitis
10.3390/antiox11020227 · 2022 · External reference
Presence and functional activity of the aryl hydrocarbon receptor in isolated murine cerebral vascular endothelial cells and astrocytes
10.1016/j.neuro.2003.08.007 · 2004 · External reference
Differential properties of astrocyte calcium waves mediated by P2Y1 and P2Y2 receptors
10.1523/jneurosci.23-17-06728.2003 · 2003 · External reference
Indoleamine 2,3-dioxygenase 1/aryl hydrocarbon receptor feedback loop mediates anti-inflammation in lipopolysaccharide-stimulated astrocytes to dampen inflammatory neurotoxicity
10.4103/ejpi.ejpi-d-24-00089 · 2025 · External reference
The glutamate-aspartate transporter GLAST mediates glutamate uptake at inner hair cell afferent synapses in the mammalian cochlea
10.1523/jneurosci.1545-06.2006 · 2006 · External reference
Impulse noise induced hidden hearing loss, hair cell ciliary changes and oxidative stress in mice
10.3390/antiox10121880 · 2021 · External reference
The PAS superfamily: sensors of environmental and developmental signals
10.1146/annurev.pharmtox.40.1.519 · 2000 · External reference
NF-κB in biology and targeted therapy: new insights and translational implications
10.1038/s41392-024-01757-9 · 2024 · External reference
Hearing loss prevalence and years lived with disability, 1990-2019: findings from the global burden of disease study 2019
10.1016/s0140-6736(21)00516-x · 2021 · External reference
AhR inhibition promotes axon regeneration via a stress–growth switch
10.1038/s41586-026-10295-z · 2026 · External reference
The roles of microglia and astrocytes in neuroinflammation of Alzheimer’s disease
10.3389/fnins.2025.1575453 · 2025 · External reference
The Aryl Hydrocarbon Receptor Complex
10.1146/annurev.pa.35.040195.001515 · 1995 · External reference
Large scale gene expression profiles of regenerating inner ear sensory epithelia
10.1371/journal.pone.0000525 · 2007 · External reference
Hearing loss and Cochlear pathology in monkeys after noise exposure
10.3109/00016487609119971 · 1976 · External reference
Cochlear supporting cells function as macrophage-like cells and protect audiosensory receptor hair cells from pathogens
10.1038/s41598-020-63654-9 · 2020 · External reference
Mononuclear phagocytes migrate into the murine cochlea after acoustic trauma
10.1002/cne.20619 · 2005 · External reference
Cloning of a factor required for activity of the ah (dioxin) receptor
10.1126/science.1852076 · 1991 · External reference
Activation of the aryl hydrocarbon receptor in inflammatory bowel disease: insights from gut microbiota
10.3389/fcimb.2023.1279172 · 2023 · External reference
In vivo real-time imaging reveals megalin as the aminoglycoside gentamicin transporter into cochlea whose inhibition is otoprotective
10.1073/pnas.2117946119 · 2022 · External reference
ORC-13661 protects sensory hair cells from aminoglycoside and cisplatin ototoxicity
10.1172/jci.insight.126764 · 2019 · External reference
Coordinate regulation of phase I and II xenobiotic metabolisms by the ah receptor and Nrf2
10.1016/j.bcp.2007.01.009 · 2007 · External reference
Characterization of the development of the mouse cochlear epithelium at the single cell level
10.1038/s41467-020-16113-y · 2020 · External reference
Novel QUEST MRI in vivo measurement of noise-induced oxidative stress in the cochlea
10.1038/s41598-019-52439-4 · 2019 · External reference
Adding insult to injury: Cochlear nerve degeneration after “temporary” noise-induced hearing loss
10.1523/jneurosci.2845-09.2009 · 2009 · External reference
Cellular mechanisms of noise-induced hearing loss
10.1016/j.heares.2016.11.013 · 2017 · External reference
Purinergic control of intercellular communication between Hensen’s cells of the guinea-pig cochlea
10.1111/j.1469-7793.2001.0693h.x · 2001 · External reference
Damage-induced activation of ERK1/2 in Cochlear supporting cells is a hair cell death-promoting signal that depends on extracellular ATP and calcium
10.1523/jneurosci.4914-07.2008 · 2008 · External reference
Damage-induced cell–cell communication in different cochlear cell types via two distinct ATP-dependent Ca2+ waves
10.1007/s11302-010-9193-8 · 2010 · External reference
Deletion or activation of the aryl hydrocarbon receptor alters adult hippocampal neurogenesis and contextual fear memory
10.1111/jnc.12130 · 2013 · External reference
Aryl hydrocarbon receptor mediates both proinflammatory and anti-inflammatory effects in lipopolysaccharide-activated microglia
10.1002/glia.22805 · 2015 · External reference
Calcium to NF-κB Signaling Pathways in Neurons
2003 · External reference
Astrocyte crosstalk in CNS inflammation
10.1016/j.neuron.2020.08.012 · 2020 · External reference
Unresolved reference
2020 · External reference
Inner ear supporting cells protect hair cells by secreting HSP70
10.1172/jci68480 · 2013 · External reference
Quantitative analysis of supporting cell subtype labeling among CreER lines in the neonatal mouse cochlea
10.1007/s10162-016-0598-0 · 2017 · External reference
Spontaneous hair cell regeneration is prevented by increased notch signaling in supporting cells
10.3389/fncel.2018.00120 · 2018 · External reference
Whole mount dissection and immunofluorescence of the adult mouse cochlea
10.3791/53561 · 2016 · External reference
Lead roles for supporting actors: critical functions of inner ear supporting cells
10.1016/j.heares.2013.01.008 · 2013 · External reference
New trends in aryl hydrocarbon receptor biology
10.3389/fcell.2016.00045 · 2016 · External reference
Activation of extracellular signal-regulated kinase by stretch-induced injury in astrocytes involves extracellular ATP and P2 purinergic receptors
10.1523/jneurosci.23-06-02348.2003 · 2003 · External reference
Aryl hydrocarbon receptor (AHR): “pioneer member” of the basic-helix/loop/helix per-Arnt-Sim (bHLH/PAS) family of “sensors” of foreign and endogenous signals
10.1016/j.plipres.2017.06.001 · 2017 · External reference
Role of the Aromatic Hydrocarbon Receptor and [Ah] Gene Battery in the Oxidative Stress Response, Cell Cycle Control, and Apoptosis
1999 · External reference
The search for endogenous activators of the aryl hydrocarbon receptor
10.1021/tx7001965 · 2008 · External reference
Sox2 and Jagged1 expression in Normal and drug-damaged adult mouse inner ear
10.1007/s10162-007-0106-7 · 2008 · External reference
AhR regulation of amyloid beta-induced inflammation in astrocyte cells
10.3389/fncel.2025.1618209 · 2025 · External reference
The role of AhR in the hallmarks of brain aging: friend and foe
10.3390/cells10102729 · 2021 · External reference
Aryl hydrocarbon receptor deficiency enhances astrocyte sensitivity to LPS-induced inflammation
10.3389/fncel.2025.1653109 · 2025 · External reference
Effects of astrocytes and microglia on neuroinflammation after spinal cord injury and related immunomodulatory strategies
10.1016/j.intimp.2022.108754 · 2022 · External reference
Computational analysis of mRNA expression profiling in the inner ear reveals candidate transcription factors associated with proliferation, differentiation, and deafness
10.1186/s40246-018-0161-7 · 2018 · External reference
Distribution of mRNAs encoding the arylhydrocarbon receptor, arylhydrocarbon receptor nuclear translocator, and arylhydrocarbon receptor nuclear translocator-2 in the rat brain and brainstem
10.1002/1096-9861(20001120)427:3<428::aid-cne9>3.0.co;2-p · 2000 · External reference
A new mathematical model for relative quantification in real-time RT-PCR
10.1093/nar/29.9.e45 · 2001 · External reference
Purinergic signalling and intercellular Ca2+ wave propagation in the organ of Corti
10.1016/j.ceca.2006.05.005 · 2007 · External reference
Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase
10.1016/s0021-9258(17)33205-2 · 1976 · External reference
Role of the PAS domain in regulation of dimerization and DNA binding specificity of the dioxin receptor
10.1128/mcb.18.7.4079 · 1998 · External reference
Priorities for hearing loss prevention and estimates of global cause-specific burdens of hearing loss: a systematic rapid review
10.1016/s2214-109x(23)00514-4 · 2024 · External reference
Identification of the ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the ah receptor
10.1126/science.256.5060.1193 · 1992 · External reference
Aryl hydrocarbon receptor: the master regulator of immune responses in allergic diseases
10.3389/fimmu.2022.1057555 · 2022 · External reference
Aryl hydrocarbon receptor activation in astrocytes by laquinimod ameliorates autoimmune inflammation in the CNS
10.1212/nxi.0000000000000946 · 2021 · External reference
Localization of fatty acid binding proteins (FABPs) in the cochlea of mice
10.1016/j.aanat.2010.06.007 · 2010 · External reference
ATP-evoked increases in intracellular calcium in neurons and glia from the dorsal spinal cord
10.1523/jneurosci.14-03-01563.1994 · 1994 · External reference
Gene expression by mouse inner ear hair cells during development
10.1523/jneurosci.5126-14.2015 · 2015 · External reference
Structural basis for aryl hydrocarbon receptor-mediated gene activation
10.1016/j.str.2017.05.008 · 2017 · External reference
Astrocytes respond to environment-relevant doses TCDD in a specific manner which is different from the endogenous AhR ligand (FICZ)
10.1021/envhealth.4c00189 · 2025 · External reference
Involvement of aryl hydrocarbon receptor in myelination and in human nerve sheath tumorigenesis
10.1073/pnas.1715999115 · 2018 · External reference
The time course of monocytes infiltration after acoustic overstimulation
10.3389/fncel.2022.844480 · 2022 · External reference
Expression of candidate markers for stem/progenitor cells in the inner ears of developing and adult GFAP and nestin promoter-GFP transgenic mice
10.1016/j.gep.2010.08.008 · 2011 · External reference
Astrocytes in neuroinflammation and brain cancer
10.1186/s43556-026-00439-y · External reference
Attenuation of microglial aryl hydrocarbon receptor alters astrocyte activation and chronic pain sensitization in aging
10.1515/biol-2025-1261 · External reference
Design and construction of 2A peptide-linked multicistronic vectors
10.1101/pdb.ip067876 · 2012 · External reference
Immune cell recruitment following acoustic trauma
10.1016/j.heares.2006.09.004 · 2006 · External reference
Oxidative DNA damage is associated with intense noise exposure in the rat
2002 · External reference
Polybrominated Dibenzo-p-dioxins, dibenzofurans, and biphenyls: inclusion in the toxicity equivalency factor concept for dioxin-like compounds
10.1093/toxsci/kft070 · 2013 · External reference
Purinergic Signalling in the cochlea
10.3390/ijms232314874 · 2022 · External reference
Cross-talk between aryl hydrocarbon receptor and the inflammatory response
10.1074/jbc.m113.505578 · 2014 · External reference
Aryl hydrocarbon receptor-dependent liver development and hepatotoxicity are mediated by different cell types
2005 · External reference
Approaches for the study of epigenetic modifications in the inner ear and related tissues
10.1016/j.heares.2019.01.007 · 2019 · External reference
Sox2-CreER mice are useful for fate mapping of mature, but not neonatal, cochlear supporting cells in hair cell regeneration studies
10.1038/srep11621 · 2015 · External reference
Inner ear supporting cells: rethinking the silent majority
10.1016/j.semcdb.2013.03.009 · 2013 · External reference
Calcium regulation of neuronal gene expression
10.1073/pnas.191352298 · 2001 · External reference
Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells
10.1038/nature04849 · 2006 · External reference
Aryl hydrocarbon receptor expression and activity in cerebellar granule neuroblasts: implications for development and dioxin neurotoxicity
10.1093/toxsci/kfi031 · 2004 · External reference
Damage-evoked signals in cochlear neurons and supporting cells
10.3389/fneur.2024.1361747 · 2024 · External reference
Canonical and non-canonical aryl hydrocarbon receptor signaling pathways
10.1016/j.cotox.2017.01.001 · 2017 · External reference
Expression of aryl hydrocarbon receptor in rat brain lesions following traumatic brain injury
10.1186/s13000-016-0522-2 · 2016 · External reference
Delayed production of free radicals following noise exposure
10.1016/j.brainres.2004.05.104 · 2004 · External reference
Adenosine triphosphate (ATP) inhibits voltage-sensitive potassium currents in isolated Hensen’s cells and Nifedipine protects against noise-induced hearing loss in Guinea pigs
10.12659/msm.898150 · 2016 · External reference
Astrocyte biology in CNS inflammatory diseases: a clinical-translational perspective
10.1212/nxi.0000000000200529 · 2026 · External reference
AhR activation mitigates graft-versus-host disease of the central nervous system by reducing microglial NF-κB signaling
10.1182/bloodadvances.2024015000 · 2025 · External reference
Nuclear receptor AHR-mediated xenobiotic detoxification pathway involves in atrazine-induced nephrotoxicity in quail (Coturnix C. coturnix)
10.1016/j.envpol.2019.07.058 · 2019 · External reference
Supporting cells-a new area in cochlear physiology study
2008 · External reference
Dynamic changes of activated AHR in microglia and astrocytes in the substantia nigra-striatum system in an MPTP-induced Parkinson’s disease mouse model
10.1016/j.brainresbull.2021.08.013 · 2021 · External reference
Distribution of mRNAs encoding the arylhydrocarbon receptor, arylhydrocarbon receptor nuclear translocator, and arylhydrocarbon receptor nuclear translocator-2 in the rat brain and brainstem
10.1002/1096-9861(20001120)427:3<428::aid-cne9>3.0.co;2-p · ExternalCitation · doi-reference
Mononuclear phagocytes migrate into the murine cochlea after acoustic trauma
10.1002/cne.20619 · ExternalCitation · doi-reference
Characterization of a unique cell population marked by transgene expression in the adult cochlea of nestin-CreERT2 /tdTomato-reporter mice
10.1002/cne.23747 · ExternalCitation · doi-reference
Aryl hydrocarbon receptor mediates both proinflammatory and anti-inflammatory effects in lipopolysaccharide-activated microglia
10.1002/glia.22805 · ExternalCitation · doi-reference
2,3,7,8-Tetrachlorodibenzo-p-dioxin receptors regulate transcription of the cytochrome P1-450 gene
10.1002/jcb.240350208 · ExternalCitation · doi-reference
Sox2 and Jagged1 expression in Normal and drug-damaged adult mouse inner ear
10.1007/s10162-007-0106-7 · ExternalCitation · doi-reference
Quantitative analysis of supporting cell subtype labeling among CreER lines in the neonatal mouse cochlea
10.1007/s10162-016-0598-0 · ExternalCitation · doi-reference
Damage-induced cell–cell communication in different cochlear cell types via two distinct ATP-dependent Ca2+ waves
10.1007/s11302-010-9193-8 · ExternalCitation · doi-reference
Intercellular signaling in glial cells: calcium waves and oscillations in response to mechanical stimulation and glutamate
10.1016/0896-6273(91)90238-u · ExternalCitation · doi-reference
Localization of fatty acid binding proteins (FABPs) in the cochlea of mice
10.1016/j.aanat.2010.06.007 · ExternalCitation · doi-reference
Coordinate regulation of phase I and II xenobiotic metabolisms by the ah receptor and Nrf2
10.1016/j.bcp.2007.01.009 · ExternalCitation · doi-reference
Delayed production of free radicals following noise exposure
10.1016/j.brainres.2004.05.104 · ExternalCitation · doi-reference
Dynamic changes of activated AHR in microglia and astrocytes in the substantia nigra-striatum system in an MPTP-induced Parkinson’s disease mouse model
10.1016/j.brainresbull.2021.08.013 · ExternalCitation · doi-reference
Purinergic signalling and intercellular Ca2+ wave propagation in the organ of Corti
10.1016/j.ceca.2006.05.005 · ExternalCitation · doi-reference
Canonical and non-canonical aryl hydrocarbon receptor signaling pathways
10.1016/j.cotox.2017.01.001 · ExternalCitation · doi-reference
And now for something completely different: diversity in ligand-dependent activation of ah receptor responses
10.1016/j.cotox.2017.01.006 · ExternalCitation · doi-reference
Nrf2 and AhR in metabolic reprogramming after contaminant exposure
10.1016/j.cotox.2017.12.001 · ExternalCitation · doi-reference
Nuclear receptor AHR-mediated xenobiotic detoxification pathway involves in atrazine-induced nephrotoxicity in quail (Coturnix C. coturnix)
10.1016/j.envpol.2019.07.058 · ExternalCitation · doi-reference
Expression of candidate markers for stem/progenitor cells in the inner ears of developing and adult GFAP and nestin promoter-GFP transgenic mice
10.1016/j.gep.2010.08.008 · ExternalCitation · doi-reference
Immune cell recruitment following acoustic trauma
10.1016/j.heares.2006.09.004 · ExternalCitation · doi-reference
Lead roles for supporting actors: critical functions of inner ear supporting cells
10.1016/j.heares.2013.01.008 · ExternalCitation · doi-reference
Cellular mechanisms of noise-induced hearing loss
10.1016/j.heares.2016.11.013 · ExternalCitation · doi-reference
Approaches for the study of epigenetic modifications in the inner ear and related tissues
10.1016/j.heares.2019.01.007 · ExternalCitation · doi-reference
Supporting cell involvement in cochlear damage and repair: novel insights from a quantitative analysis of cyclodextrin-induced ototoxicity in mice
10.1016/j.heares.2025.109201 · ExternalCitation · doi-reference
Effects of astrocytes and microglia on neuroinflammation after spinal cord injury and related immunomodulatory strategies
10.1016/j.intimp.2022.108754 · ExternalCitation · doi-reference
A protocol for cryoembedding the adult guinea pig cochlea for fluorescence immunohistology
10.1016/j.jneumeth.2008.09.007 · ExternalCitation · doi-reference
P2X7 receptor is required for the ototoxicity caused by aminoglycoside in developing cochlear hair cells
10.1016/j.nbd.2023.106176 · ExternalCitation · doi-reference
Presence and functional activity of the aryl hydrocarbon receptor in isolated murine cerebral vascular endothelial cells and astrocytes
10.1016/j.neuro.2003.08.007 · ExternalCitation · doi-reference
Regulated reprogramming in the regeneration of sensory receptor cells
10.1016/j.neuron.2011.07.015 · ExternalCitation · doi-reference
Astrocyte crosstalk in CNS inflammation
10.1016/j.neuron.2020.08.012 · ExternalCitation · doi-reference
Aryl hydrocarbon receptor (AHR): “pioneer member” of the basic-helix/loop/helix per-Arnt-Sim (bHLH/PAS) family of “sensors” of foreign and endogenous signals
10.1016/j.plipres.2017.06.001 · ExternalCitation · doi-reference
Inner ear supporting cells: rethinking the silent majority
10.1016/j.semcdb.2013.03.009 · ExternalCitation · doi-reference
Sox2+ adult stem and progenitor cells are important for tissue regeneration and survival of mice
10.1016/j.stem.2011.09.001 · ExternalCitation · doi-reference
Structural basis for aryl hydrocarbon receptor-mediated gene activation
10.1016/j.str.2017.05.008 · ExternalCitation · doi-reference
Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase
10.1016/s0021-9258(17)33205-2 · ExternalCitation · doi-reference
Hearing loss prevalence and years lived with disability, 1990-2019: findings from the global burden of disease study 2019
10.1016/s0140-6736(21)00516-x · ExternalCitation · doi-reference
Immunolocalization of the calcium binding S100A1, S100A5 and S100A6 proteins in the dog cochlea during postnatal development
10.1016/s0165-3806(00)00153-x · ExternalCitation · doi-reference
Priorities for hearing loss prevention and estimates of global cause-specific burdens of hearing loss: a systematic rapid review
10.1016/s2214-109x(23)00514-4 · ExternalCitation · doi-reference
Astrocytes respond to environment-relevant doses TCDD in a specific manner which is different from the endogenous AhR ligand (FICZ)
10.1021/envhealth.4c00189 · ExternalCitation · doi-reference
The search for endogenous activators of the aryl hydrocarbon receptor
10.1021/tx7001965 · ExternalCitation · doi-reference
Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells
10.1038/nature04849 · ExternalCitation · doi-reference
NF-κB in biology and targeted therapy: new insights and translational implications
10.1038/s41392-024-01757-9 · ExternalCitation · doi-reference
The aryl hydrocarbon receptor: structure, signaling, physiology and pathology
10.1038/s41392-025-02500-8 · ExternalCitation · doi-reference
Characterization of the development of the mouse cochlear epithelium at the single cell level
10.1038/s41467-020-16113-y · ExternalCitation · doi-reference
Structural basis for the ligand-dependent activation of heterodimeric AHR-ARNT complex
10.1038/s41467-025-56574-7 · ExternalCitation · doi-reference
AhR inhibition promotes axon regeneration via a stress–growth switch
10.1038/s41586-026-10295-z · ExternalCitation · doi-reference
Novel QUEST MRI in vivo measurement of noise-induced oxidative stress in the cochlea
10.1038/s41598-019-52439-4 · ExternalCitation · doi-reference
Cochlear supporting cells function as macrophage-like cells and protect audiosensory receptor hair cells from pathogens
10.1038/s41598-020-63654-9 · ExternalCitation · doi-reference
Sox2-CreER mice are useful for fate mapping of mature, but not neonatal, cochlear supporting cells in hair cell regeneration studies
10.1038/srep11621 · ExternalCitation · doi-reference
Critical role of ATP-induced ATP release for Ca2+ signaling in nonsensory cell networks of the developing cochlea
10.1073/pnas.1616061113 · ExternalCitation · doi-reference
Involvement of aryl hydrocarbon receptor in myelination and in human nerve sheath tumorigenesis
10.1073/pnas.1715999115 · ExternalCitation · doi-reference
Calcium regulation of neuronal gene expression
10.1073/pnas.191352298 · ExternalCitation · doi-reference
In vivo real-time imaging reveals megalin as the aminoglycoside gentamicin transporter into cochlea whose inhibition is otoprotective
10.1073/pnas.2117946119 · ExternalCitation · doi-reference
Cloning of the ah-receptor cDNA reveals a distinctive ligand-activated transcription factor
10.1073/pnas.89.17.8185 · ExternalCitation · doi-reference
Cross-talk between aryl hydrocarbon receptor and the inflammatory response
10.1074/jbc.m113.505578 · ExternalCitation · doi-reference
A new mathematical model for relative quantification in real-time RT-PCR
10.1093/nar/29.9.e45 · ExternalCitation · doi-reference
Aryl hydrocarbon receptor expression and activity in cerebellar granule neuroblasts: implications for development and dioxin neurotoxicity
10.1093/toxsci/kfi031 · ExternalCitation · doi-reference
Polybrominated Dibenzo-p-dioxins, dibenzofurans, and biphenyls: inclusion in the toxicity equivalency factor concept for dioxin-like compounds
10.1093/toxsci/kft070 · ExternalCitation · doi-reference
Design and construction of 2A peptide-linked multicistronic vectors
10.1101/pdb.ip067876 · ExternalCitation · doi-reference
Purinergic control of intercellular communication between Hensen’s cells of the guinea-pig cochlea
10.1111/j.1469-7793.2001.0693h.x · ExternalCitation · doi-reference
Deletion or activation of the aryl hydrocarbon receptor alters adult hippocampal neurogenesis and contextual fear memory
10.1111/jnc.12130 · ExternalCitation · doi-reference
Cloning of a factor required for activity of the ah (dioxin) receptor
10.1126/science.1852076 · ExternalCitation · doi-reference
Identification of the ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the ah receptor
10.1126/science.256.5060.1193 · ExternalCitation · doi-reference
Role of the PAS domain in regulation of dimerization and DNA binding specificity of the dioxin receptor
10.1128/mcb.18.7.4079 · ExternalCitation · doi-reference
The Aryl Hydrocarbon Receptor Complex
10.1146/annurev.pa.35.040195.001515 · ExternalCitation · doi-reference
The PAS superfamily: sensors of environmental and developmental signals
10.1146/annurev.pharmtox.40.1.519 · ExternalCitation · doi-reference
Activation of the NF κ B pathway enhances AhR expression in intestinal Caco-2 cells
10.1155/2013/792452 · ExternalCitation · doi-reference
Antioxidant functions of the aryl hydrocarbon receptor
10.1155/2016/7943495 · ExternalCitation · doi-reference
ORC-13661 protects sensory hair cells from aminoglycoside and cisplatin ototoxicity
10.1172/jci.insight.126764 · ExternalCitation · doi-reference
Exosomes mediate sensory hair cell protection in the inner ear
10.1172/jci128867 · ExternalCitation · doi-reference
Inner ear supporting cells protect hair cells by secreting HSP70
10.1172/jci68480 · ExternalCitation · doi-reference
AhR activation mitigates graft-versus-host disease of the central nervous system by reducing microglial NF-κB signaling
10.1182/bloodadvances.2024015000 · ExternalCitation · doi-reference
Expression of aryl hydrocarbon receptor in rat brain lesions following traumatic brain injury
10.1186/s13000-016-0522-2 · ExternalCitation · doi-reference
Computational analysis of mRNA expression profiling in the inner ear reveals candidate transcription factors associated with proliferation, differentiation, and deafness
10.1186/s40246-018-0161-7 · ExternalCitation · doi-reference
Astrocytes in neuroinflammation and brain cancer
10.1186/s43556-026-00439-y · ExternalCitation · doi-reference
Aryl hydrocarbon receptor activation in astrocytes by laquinimod ameliorates autoimmune inflammation in the CNS
10.1212/nxi.0000000000000946 · ExternalCitation · doi-reference
Astrocyte biology in CNS inflammatory diseases: a clinical-translational perspective
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Gene expression by mouse inner ear hair cells during development
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