Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from Natural product FZJDXJ enhances CD8+ T-cell glycolysis to relieve exhaustion and augment antitumor immunity in HBV+ hepatocellular carcinoma. Local targets link to admitted publications; unresolved targets remain external evidence.
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
10.3322/caac.21834 · 2024 · External reference
The liver cancer immune microenvironment: therapeutic implications for hepatocellular carcinoma
10.1002/hep.32740 · 2023 · External reference
Metabolic targeting of regulatory T cells in oral squamous cell carcinoma: new horizons in immunotherapy
10.1186/s12943-024-02193-7 · 2024 · External reference
IFNα potentiates Anti-PD-1 efficacy by remodeling glucose metabolism in the hepatocellular carcinoma microenvironment
10.1158/2159-8290.cd-21-1022 · 2022 · External reference
Characteristics of immune response to tumor-associated antigens and immune cell profile in patients with hepatocellular carcinoma
10.1002/hep.30212 · 2019 · External reference
Metabolic plasticity and regulation of T cell exhaustion
10.1111/imm.13575 · 2022 · External reference
Immunotherapies for hepatocellular carcinoma
10.1038/s41571-021-00573-2 · 2022 · External reference
Traditional Chinese medicine for prevention and treatment of hepatocellular carcinoma: a focus on epithelial-mesenchymal transition
10.1016/j.joim.2021.08.004 · 2021 · External reference
Toll-like receptor 7 activation enhances CD8+ T cell effector functions by promoting cellular glycolysis
10.3389/fimmu.2019.02191 · 2019 · External reference
Adjunctive traditional Chinese medicine therapy improves survival of liver cancer patients
10.1111/liv.12847 · 2015 · External reference
Cancer metabolism: looking forward
10.1038/s41568-021-00378-6 · 2021 · External reference
Exploring pharmacological active ingredients of traditional Chinese medicine by pharmacotranscriptomic map in ITCM
10.1093/bib/bbad027 · 2023 · External reference
COIMMR: a computational framework to reveal the contribution of herbal ingredients against human cancer via immune microenvironment and metabolic reprogramming
10.1093/bib/bbad346 · 2023 · External reference
Efficacy and safety of Fuzheng Jiedu Xiaoji formula combined with conventional western therapy in advanced HBV-HCC: a single-center, randomized controlled trial
10.1007/s11655-025-3835-8 · 2025 · External reference
Traditional Chinese medicine targeting cancer stem cells as an alternative treatment for hepatocellular carcinoma
10.1016/j.joim.2020.02.002 · 2020 · External reference
Immunosuppressive tumor microenvironment and immunotherapy of hepatocellular carcinoma: current status and prospectives
10.1186/s13045-024-01549-2 · 2024 · External reference
GSFM: a genome-scale functional module transformation to represent drug efficacy for in silico drug discovery
10.1016/j.apsb.2024.08.017 · 2025 · External reference
Network medicine-based strategy identifies maprotiline as a repurposable drug by inhibiting PD-L1 expression via targeting SPOP in cancer
10.1002/advs.202410285 · 2025 · External reference
Traditional Chinese medicine enhances the effectiveness of immune checkpoint inhibitors in tumor treatment: a mechanism discussion
10.1016/j.jep.2024.118955 · 2025 · External reference
Molecular and cellular insights into T cell exhaustion
10.1038/nri3862 · 2015 · External reference
Crosstalk between glucose metabolism, lactate production and immune response modulation
10.1016/j.cytogfr.2022.11.001 · 2022 · External reference
Fuzheng Jiedu Xiaoji formulation inhibits hepatocellular carcinoma progression in patients by targeting the AKT/CyclinD1/p21/p27 pathway
10.1016/j.phymed.2021.153575 · 2021 · External reference
Yangyin Fuzheng Jiedu Prescription exerts anti-tumor immunity in hepatocellular carcinoma by alleviating exhausted T cells
10.1016/j.phymed.2021.153722 · 2021 · External reference
Compound kushen injection relieves tumor-associated macrophage-mediated immunosuppression through TNFR1 and sensitizes hepatocellular carcinoma to sorafenib
10.1136/jitc-2019-000317 · 2020 · External reference
Lactate supports Treg function and immune balance via MGAT1 effects on N-glycosylation in the mitochondria
10.1172/jci175897 · 2024 · External reference
Hepatocellular carcinoma: updates on epidemiology, surveillance, diagnosis and treatment
10.3350/cmh.2024.0824 · 2025 · External reference
The tumor microenvironment in hepatocellular carcinoma: mechanistic insights and therapeutic potential of traditional Chinese medicine
10.1186/s12943-025-02378-8 · 2025 · External reference
Traditional Chinese medicine and natural products in management of hepatocellular carcinoma: biological mechanisms and therapeutic potential
10.1016/j.phrs.2025.107733 · 2025 · External reference
Identifying antihepatocellular carcinoma compounds in Gansui Banxia decoction using live cell adsorption
10.2147/dddt.s513086 · 2025 · External reference