Research graph
References from Effects of L-theanine on cognition, mood and sleep: evidence from human trials. Local targets link to admitted publications; unresolved targets remain external evidence.
Occurrence, biosynthesis and metabolism of theanine (γ-glutamyl-L-ethylamide) in plants: a comprehensive review
10.1177/1934578x1501000525 · 2015 · External reference
L-theanine and immunity: a review
10.3390/molecules28093846 · 2023 · External reference
Pharmaceutical activities of theanine: a phytochemical nutrient
10.1002/fsn3.70811 · 2025 · External reference
et al. L-theanine: a unique functional amino acid in tea (Camellia sinensis L) with multiple health benefits and food applications
10.3389/fnut.2022.853846 · 2022 · External reference
L-theanine, unique amino acid of tea, and its metabolism, health effects, and safety
10.1080/10408398.2015.1016141 · 2017 · External reference
Kinetics of L-theanine uptake and metabolism in healthy participants are comparable after ingestion of L-theanine via capsules and green tea
10.3945/jn.112.166371 · 2012 · External reference
Human disposition of L-theanine in tea or aqueous solution
10.1016/j.jff.2010.08.001 · 2010 · External reference
Neurobiological effects of the green tea constituent theanine and its potential role in the treatment of psychiatric and neurodegenerative disorders
10.1179/1476830513y.0000000079 · 2014 · External reference
The neuropharmacology of L-theanine (N-ethyl-L-glutamine): a possible neuroprotective and cognitive enhancing agent
10.1080/j157v06n02_02 · 2006 · External reference
How does the tea L-theanine buffer stress and anxiety
10.1016/j.fshw.2021.12.004 · 2022 · External reference
Nutraceuticals as potential targets for the development of a functional beverage for improving sleep quality
10.3390/beverages7020033 · 2021 · External reference
L-theanine: from tea leaf to trending supplement - does the science match the hype for brain health and relaxation?
10.1016/j.nutres.2024.12.008 · 2025 · External reference
Promising, but not completely conclusive-the effect of L-theanine on cognitive performance based on the systematic review and meta-analysis of randomized placebo-controlled clinical trials
10.3390/jcm14217710 · 2025 · External reference
Effects of tea (Camellia sinensis) or its bioactive compounds L-theanine or L-theanine plus caffeine on cognition, sleep, and mood in healthy participants: a systematic review and meta-analysis of randomized controlled trials
10.1093/nutrit/nuaf054 · 2025 · External reference
L-theanine improves neurophysiological measures of attention in a dose-dependent manner: a double-blind, placebo-controlled, crossover study
10.1080/1028415x.2020.1804098 · 2022 · External reference
Dose-response effect of L-theanine on psychomotor speed, sustained attention, and inhibitory control: a double-blind, placebo-controlled, crossover study
10.1080/1028415x.2022.2136884 · 2023 · External reference
10.1007/s00213-025-06775-1
10.1007/s00213-025-06775-1 · 2025 · External reference
Improvement of both human and animal memory by synergy between fructooligosaccharide and L-theanine function establishing a safe and effective food supplement
10.1002/fsn3.4145 · 2024 · External reference
A combination of green tea extract and l-theanine improves memory and attention in subjects with mild cognitive impairment: a double-blind placebo-controlled study
10.1089/jmf.2009.1374 · 2011 · External reference
Synergistic effects of caffeine, l-theanine, and diaphragmatic breathing on esports performance: a randomized controlled crossover trial
10.1016/j.nutres.2026.04.007 · 2026 · External reference
The effects of L-theanine, caffeine and their combination on cognition and mood
10.1016/j.biopsycho.2007.09.008 · 2008 · External reference
Acute effects of theanine, caffeine and theanine-caffeine combination on attention
10.1080/1028415x.2016.1144845 · 2017 · External reference
Effects of L-theanine-caffeine combination on sustained attention and inhibitory control among children with ADHD: a proof-of-concept neuroimaging RCT
10.1038/s41598-020-70037-7 · 2020 · External reference
L-theanine and caffeine in combination affect human cognition as evidenced by oscillatory alpha-band activity and attention task performance
10.1093/jn/138.8.1572s · 2008 · External reference
The combined effects of L-theanine and caffeine on cognitive performance and mood
10.1179/147683008x301513 · 2008 · External reference
Performance-enhancing effects of caffeine and L-theanine among Iranian elite wrestlers: a focus on cognitive and specific physical performance
10.1080/15502783.2025.2564238 · 2025 · External reference
Effect of single or combined caffeine and L-theanine supplementation on shooting and cognitive performance in elite curling athletes: a double-blind, placebo-controlled study
10.1080/15502783.2023.2267536 · 2023 · External reference
10.1007/s00213-015-3895-0
10.1007/s00213-015-3895-0 · 2015 · External reference
Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task
10.1016/j.neuropharm.2012.01.020 · 2012 · External reference
Effects of L-theanine and L-arginine supplementation on attention, cognitive, and shooting performance in elite air rifle shooters
10.1080/1612197x.2026.2637018 · 2026 · External reference
Global evidence on the prevalence of and risk factors associated with stress
10.1016/j.jad.2025.01.053 · 2025 · External reference
The effects of green tea amino acid L-theanine consumption on the ability to manage stress and anxiety levels: a systematic review
10.1007/s11130-019-00771-5 · 2020 · External reference
Effects of L-theanine administration on stress-related symptoms and cognitive functions in healthy adults: a randomized controlled trial
10.3390/nu11102362 · 2019 · External reference
Effect of combined ingestion of L-theanine and L-arginine for short-term psychological stress in young adults: a randomized placebo-controlled study
10.3177/jnsv.68.540 · 2022 · External reference
Effects of supplement L-theanine on cognitive anxiety, salivary alpha-amylase, and cortisol in archery competition
10.20463/pan.2024.0034 · 2024 · External reference
10.1007/s40120-021-00284-x
10.1007/s40120-021-00284-x · 2021 · External reference
Impact of L-theanine and L-tyrosine on markers of stress and cognitive performance in response to a virtual reality based active shooter training drill
10.1080/10253890.2024.2375588 · 2024 · External reference
Safety and efficacy of AlphaWave® L-theanine supplementation for 28 days in healthy adults with moderate stress: a randomized, double-blind, placebo-controlled trial
10.1007/s40120-024-00624-7 · 2024 · External reference
The effects of L-theanine supplementation on the outcomes of patients with mental disorders: a systematic review
10.1186/s12888-024-06285-y · 2024 · External reference
Medicinal herbs for the treatment of anxiety: a systematic review and network meta-analysis
10.1016/j.phrs.2022.106204 · 2022 · External reference
Comparison of the effects of two amino acids, gamma-aminobutyric acid (GABA) and L-theanine, on sedation, anxiety, and cognition in preoperative surgical patients - a randomized controlled study
10.4103/joacp.joacp_417_23 · 2025 · External reference
In search of a safe natural sleep aid
10.1080/07315724.2014.926153 · 2015 · External reference
An international survey of sleeping problems in the general population
10.1185/030079907x253771 · 2008 · External reference
Examining the effect of L-theanine on sleep: a systematic review of dietary supplementation trials
10.1080/1028415x.2025.2556925 · 2026 · External reference
The effects of L-theanine consumption on sleep outcomes: a systematic review and meta-analysis
10.1016/j.smrv.2025.102076 · 2025 · External reference
The effect of green tea amino acid L-theanine formulation on markers of stress and quality of sleep (THE Sleep project) – a study protocol for a pilot randomized control trial
10.1016/j.cct.2026.108306 · 2026 · External reference
Determination of L-theanine and caffeine contents in tea infusions with different fermentation degrees and brewing conditions using the chromatographic method
10.3390/foods14132313 · 2025 · External reference
How much theanine in a cup of tea? Effects of tea type and method of preparation
10.1016/j.foodchem.2010.08.071 · 2011 · External reference
Naturalistic investigation of the effects of day-long consumption of tea, coffee and water on alertness, sleep onset and sleep quality
10.1007/s002130000383 · 2000 · External reference
Reduced stress and improved sleep quality caused by green tea are associated with a reduced caffeine content
10.3390/nu9070777 · 2017 · External reference
L-theanine-a unique amino acid of green tea and its relaxation effect in humans
10.1016/s0924-2244(99)00044-8 · 1999 · External reference
L-theanine, a natural constituent in tea, and its effect on mental state
10.6133/apjcn.2008.17.s1.40 · 2008 · External reference
Effects of theanine on the release of brain alpha wave in adult males
2003 · External reference
Anti-stress, behavioural and magnetoencephalography effects of an L-theanine-based nutrient drink: a randomised, double-blind, placebo-controlled, crossover trial
10.3390/nu8010053 · 2016 · External reference
Theanine maintains sleep quality in healthy young women by suppressing the increase in caffeine-induced wakefulness after sleep onset
10.1039/d3fo01247f · 2023 · External reference
L-theanine partially counteracts caffeine-induced sleep disturbances in rats
10.1016/j.pbb.2012.01.011 · 2012 · External reference
Inhibiting effects of theanine on caffeine stimulation evaluated by EEG in the rat
10.1271/bbb.64.287 · 2000 · External reference
GABA and l-theanine mixture decreases sleep latency and improves NREM sleep
10.1080/13880209.2018.1557698 · 2019 · External reference
The impact of green tea and its bioactive compounds on mood disorder symptomology and brain derived neurotrophic factor: a systematic review of randomized controlled trials
10.3390/biomedicines13071656 · 2025 · External reference
Effect of green tea phytochemicals on mood and cognition
10.2174/1381612823666170105151800 · 2017 · External reference
Psychotropic effects of L-theanine and its clinical properties: from the management of anxiety and stress to a potential use in schizophrenia
10.1016/j.phrs.2019.104395 · 2019 · External reference
The cognitive-enhancing outcomes of caffeine and L-theanine: a systematic review
10.7759/cureus.20828 · 2021 · External reference
Pharmacological effects and molecular targets of L-theanine in cardiovascular diseases and comorbidities
10.1016/j.ejphar.2026.178715 · 2026 · External reference
