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References from SYTL5 drives malignant progression in differentiated thyroid carcinoma: unveiling its regulatory mechanisms. Local targets link to admitted publications; unresolved targets remain external evidence.
Cancer treatment and survivorship statistics, 2022
10.3322/caac.21731 · 2022 · External reference
Radioiodine-refractory differentiated thyroid cancer: Molecular mechanisms and therapeutic strategies for radioiodine resistance
10.1016/j.drup.2023.101013 · 2024 · External reference
The RAB27A effector SYTL5 regulates mitophagy and mitochondrial metabolism
10.7554/elife.105541.1 · 2025 · External reference
Estrogen regulates vesicle trafficking gene expression in EFF-3, EFM-19 and MCF-7 breast cancer cells
2009 · External reference
SYTL5 promotes papillary thyroid carcinoma progression by enhancing activation of the NF-κB signaling pathway
10.1210/endocr/bqac187 · 2022 · External reference
Synaptotagmin-like 5 is a potential biomarker and correlates with immune infiltrates in thyroid carcinoma
10.1007/s10735-025-10593-2 · 2025 · External reference
HNF4α-CDKL3 axis restricts MASLD progression by targeting FoxO1 via noncanonical phosphorylation
10.1097/hep.0000000000001147 · 2025 · External reference
Anti-Pan-Rspo chimeric protein-conjugated albumin nanoparticle provides promising opportunities in cancer targeted therapy
10.1002/adhm.202301441 · 2023 · External reference
Aberrant cholesterol metabolism and Wnt/β-catenin signaling coalesce via Frizzled5 in supporting cancer growth
10.1002/advs.202200750 · 2022 · External reference
Hallmarks of cancer: the next generation
10.1016/j.cell.2011.02.013 · 2011 · External reference
Cell signaling by receptor tyrosine kinases
10.1016/j.cell.2010.06.011 · 2010 · External reference
Cellular mechanisms of tumour suppression by the retinoblastoma gene
10.1038/nrc2399 · 2008 · External reference
The Bcl-2 apoptotic switch in cancer development and therapy
10.1038/sj.onc.1210220 · 2007 · External reference
Telomeres and human disease: ageing, cancer and beyond
10.1038/nrg1656 · 2005 · External reference
The angiogenic switch in carcinogenesis
10.1016/j.semcancer.2009.05.003 · 2009 · External reference
Approaches to determine nuclear shape in cells during migration through collagen matrices
10.1007/978-1-0716-2887-4_7 · 2023 · External reference
Involvement of members of the cadherin superfamily in cancer
10.1101/cshperspect.a003129 · 2009 · External reference
Genomic instability--an evolving hallmark of cancer
10.1038/nrm2858 · 2010 · External reference
Immune infiltration in human tumors: a prognostic factor that should not be ignored
10.1038/onc.2009.416 · 2010 · External reference
Tumor cell metabolism: cancer's Achilles' heel
10.1016/j.ccr.2008.05.005 · 2008 · External reference
Analysis of the genome to personalize therapy for melanoma
10.1038/onc.2010.323 · 2010 · External reference
Epithelial-mesenchymal transition: a cancer researcher's conceptual friend and foe
10.2353/ajpath.2009.080545 · 2009 · External reference
Structural biology and evolution of the TGFβ family
10.1101/cshperspect.a022103 · 2016 · External reference
Transforming growth factor-β signaling in immunity and cancer
10.1016/j.immuni.2019.03.024 · 2019 · External reference
Macrophages: master regulators of inflammation and fibrosis
10.1055/s-0030-1255354 · 2010 · External reference
Transforming growth factor-β in stem cells and tissue homeostasis
10.1038/s41413-017-0005-4 · 2018 · External reference
Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cells
10.1083/jcb1792oia4 · 2007 · External reference
Structural determinants of Smad function in TGFβ signaling
10.1016/j.tibs.2015.03.012 · 2015 · External reference
SMAD proteins in TGFβ signalling pathway in cancer: regulatory mechanisms and clinical applications
10.3390/diagnostics13172769 · 2023 · External reference
TGF β signaling: a complex role in tumorigenesis
10.3892/mmr.2017.7970 · 2018 · External reference
TGFβ: duality of function between tumor prevention and carcinogenesis
10.1093/jnci/djt369 · 2014 · External reference
TGF-beta signal transduction: biology, function and therapy for diseases
10.1186/s43556-022-00109-9 · 2022 · External reference
TGFβ family signaling in tumor suppression and cancer progression
10.1101/cshperspect.a022277 · 2017 · External reference
Paradoxical roles of TGFβ signaling in suppressing and promoting squamous cell carcinoma
10.1007/978-981-13-3798-7_42 · 2018 · External reference
Epigenetic regulation of epithelial-mesenchymal transition: focusing on hypoxia and TGFβ signaling
10.1186/s12929-020-00632-3 · 2020 · External reference
The role of TGF‐β signaling pathways in cancer and its potential as a therapeutic target
10.1155/2021/6675208 · 2021 · External reference
Integrin αvβ6-TGFβ-SOX4 pathway drives immune evasion in triple-negative breast cancer
10.1016/j.ccell.2020.12.001 · 2021 · External reference
TGFβ-mediated epithelial-mesenchymal transition and cancer metastasis
10.3390/ijms20112767 · 2019 · External reference
Metabolic reprogramming of cancer-associated fibroblasts by TGFβ drives tumor growth: connecting TGFβ signaling with “Warburg-like” cancer metabolism and L-lactate production
10.4161/cc.21384 · 2012 · External reference
Cancer cachexia: multilevel metabolic dysfunction
10.1038/s42255-024-01167-9 · 2024 · External reference
TGFβ signaling in the tumor metabolic microenvironment and targeted therapies
10.1186/s13045-022-01349-6 · 2022 · External reference
Dysregulation of the immune response in TGFβ signalopathies
10.3389/fimmu.2022.1066375 · 2022 · External reference
Therapeutic targeting of TGFβ in cancer: hacking a master switch of immune suppression
10.1042/cs20201236 · 2021 · External reference
Epigenetic targeting of transforming growth factor β receptor II and implications for cancer therapy
10.4255/mcpharmacol.09.07 · 2009 · External reference
TGF-beta/Smad pathway and BRAF mutation play different roles in circumscribed and infiltrative papillary thyroid carcinoma
10.1007/s00428-012-1234-y · 2012 · External reference
Targeting TGF-beta1 inhibits invasion of anaplastic thyroid carcinoma cell through SMAD2-dependent S100A4-MMP-2/9 signalling
2016 · External reference
Orthotopic mouse models for the preclinical and translational study of targeted therapies against metastatic human thyroid carcinoma with BRAFV600E or wild-type BRAF
10.1038/onc.2013.544 · 2014 · External reference
Nasopharyngeal carcinoma ecology theory: cancer as multidimensional spatiotemporal unity of ecology and evolution pathological ecosystem
10.7150/thno.82690 · 2023 · External reference