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References from Novel Bragg peak FLASH radiotherapy: treatment of base-of-skull tumors within existing clinical guidelines. Local targets link to admitted publications; unresolved targets remain external evidence.
Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data
10.1016/s0140-6736(00)90011-4 · 2000 · External reference
What is the most effective treatment for head and neck squamous cell carcinoma?: An individual patient data network meta-analysis from the MACH-NC and MARCH collaborative groups
10.1016/s0959-8049(17)30415-x · 2017 · External reference
Randomized phase III trial to test accelerated versus standard fractionation in combination with concurrent cisplatin for head and neck carcinomas in the Radiation Therapy Oncology Group 0129 trial: long-term report of efficacy and toxicity
10.1200/jco.2014.55.3925 · 2014 · External reference
EANO guideline on the diagnosis and management of meningiomas
10.1093/neuonc/noab150 · 2021 · External reference
Building a global consensus approach to chordoma: a position paper from the medical and patient community
10.1016/s1470-2045(14)71190-8 · 2015 · External reference
Clinical outcomes and toxicities of 100 patients treated with proton therapy for chordoma on the proton collaborative group prospective registry
10.1016/j.radonc.2023.109551 · 2023 · External reference
Comparative effectiveness of proton vs photon therapy as part of concurrent chemoradiotherapy for locally advanced cancer
10.1001/jamaoncol.2019.4889 · 2020 · External reference
Radiosurgery with photons or protons for benign and Malignant tumours of the skull base: a review
10.1186/1748-717x-7-210 · 2012 · External reference
Proton therapy for treatment of intracranial benign tumors in adults: A systematic review
10.1016/j.ctrv.2018.11.004 · 2019 · External reference
Carotid artery stenosis in asymptomatic patients who have received unilateral head-and-neck irradiation
10.1016/j.ijrobp.2005.04.017 · 2005 · External reference
Normal tissue complication probability (NTCP) models for predicting temporal lobe injury after intensity-modulated radiotherapy in nasopharyngeal carcinoma: A large registry-based retrospective study from China
10.1016/j.radonc.2021.01.008 · 2021 · External reference
Comparison of intensity-modulated radiotherapy, adaptive radiotherapy, proton radiotherapy, and adaptive proton radiotherapy for treatment of locally advanced head and neck cancer
10.1016/j.radonc.2011.05.028 · 2011 · External reference
Identification of patient benefit from proton beam therapy in brain tumour patients based on dosimetric and NTCP analyses
10.1016/j.radonc.2021.04.008 · 2021 · External reference
Temporal lobe necrosis after proton for nasopharyngeal carcinoma: Predictive factors and clinical RBE estimation
10.1016/j.ijrobp.2017.06.1526 · 2017 · External reference
Dosimetric comparison of proton radiation therapy, volumetric modulated arc therapy, and three-dimensional conformal radiotherapy based on intracranial tumor location
10.3390/cancers10110401 · 2018 · External reference
Study of relationship between dose, LET and the risk of brain necrosis after proton therapy for skull base tumors
10.1016/j.radonc.2021.08.015 · 2021 · External reference
Irradiation in a flash: Unique sparing of memory in mice after whole brain irradiation with dose rates above 100 Gy/s
10.1016/j.radonc.2017.05.003 · 2017 · External reference
Comparison of FLASH proton entrance and the spread-out Bragg peak dose regions in the sparing of mouse intestinal crypts and in a pancreatic tumor model
10.3390/cancers13164244 · 2021 · External reference
Neuroprotective effects of ultra-high dose rate FLASH Bragg peak proton irradiation
10.1016/j.ijrobp.2022.02.020 · 2022 · External reference
A computational model of radiolytic oxygen depletion during FLASH irradiation and its effect on the oxygen enhancement ratio
10.1088/1361-6560/ab3769 · 2019 · External reference
Ultra-high-dose-rate FLASH irradiation limits reactive gliosis in the brain
10.1667/rade-20-00067.1 · 2020 · External reference
Long-term neurocognitive benefits of FLASH radiotherapy driven by reduced reactive oxygen species
10.1073/pnas.1901777116 · 2019 · External reference
A physicochemical model of reaction kinetics supports peroxyl radical recombination as the main determinant of the FLASH effect
10.1016/j.radonc.2020.06.001 · 2020 · External reference
Ultra-high-dose-rate FLASH and conventional-dose-rate irradiation differentially affect human acute lymphoblastic leukemia and normal hematopoiesis
10.1016/j.ijrobp.2020.10.012 · 2021 · External reference
FLASH proton radiotherapy spares normal epithelial and mesenchymal tissues while preserving sarcoma response
10.1158/0008-5472.can-21-1500 · 2021 · External reference
Treatment of a first patient with FLASH-radiotherapy
10.1016/j.radonc.2019.06.019 · 2019 · External reference
FLASH radiotherapy: History and future
10.3389/fonc.2021.644400 · 2021 · External reference
Experimental set-up for FLASH proton irradiation of small animals using a clinical system
10.1016/j.ijrobp.2018.06.403 · 2018 · External reference
Proton FLASH radiotherapy for the treatment of symptomatic bone metastases: the FAST-01 nonrandomized trial
10.1001/jamaoncol.2022.5843 · 2023 · External reference
FLASH radiotherapy for the treatment of symptomatic bone metastases (FAST-01): protocol for the first prospective feasibility study
10.2196/41812 · 2023 · External reference
Towards FLASH proton therapy: the impact of treatment planning and machine characteristics on achievable dose rates
10.1080/0284186x.2019.1627416 · 2019 · External reference
A novel proton pencil beam scanning FLASH RT delivery method enables optimal OAR sparing and ultra-high dose rate delivery: A comprehensive dosimetry study for lung tumors
10.3390/cancers13225790 · 2021 · External reference
A universal range shifter and range compensator can enable proton pencil beam scanning single-energy Bragg peak FLASH-RT treatment using current commercially available proton systems
10.1016/j.ijrobp.2022.01.009 · 2022 · External reference
Development of the open-source dose calculation and optimization toolkit matRad
10.1002/mp.12251 · 2017 · External reference
Applications of various range shifters for proton pencil beam scanning radiotherapy
10.1186/s13014-021-01873-8 · 2021 · External reference
A framework for defining FLASH dose rate for pencil beam scanning
10.1002/mp.14456 · 2020 · External reference
ESTRO ACROP guideline for target volume delineation of skull base tumors
10.1016/j.radonc.2020.11.014 · 2021 · External reference
Quantitative assessment of 3D dose rate for proton pencil beam scanning FLASH radiotherapy and its application for lung hypofractionation treatment planning
10.3390/cancers13143549 · 2021 · External reference
FLASH radiotherapy using single-energy proton PBS transmission beams for hypofractionation liver cancer: Dose and dose rate quantification
10.3389/fonc.2021.813063 · 2021 · External reference
Advanced pencil beam scanning Bragg peak FLASH-RT delivery technique can enhance lung cancer planning treatment outcomes compared to conventional multiple-energy proton PBS techniques
10.1016/j.radonc.2022.08.005 · 2022 · External reference
Use of single-energy proton pencil beam scanning Bragg peak for intensity-modulated proton therapy FLASH treatment planning in liver-hypofractionated radiation therapy
10.1002/mp.15894 · 2022 · External reference
The potential and challenges of proton FLASH in head and neck cancer reirradiation
10.3390/cancers16193249 · 2024 · External reference
Conditional sparing in FLASH radiotherapy: Conformal dosimetry and ALARA remain essential
10.1002/acm2.70664 · 2026 · External reference
Mortality of early treatment for radiation-induced brain necrosis in head and neck cancer survivors: a multicentre, retrospective, registry-based cohort study
10.1016/j.eclinm.2022.101618 · 2022 · External reference
The sparing effect of FLASH-RT on synaptic plasticity is maintained in mice with standard fractionation
10.1016/j.radonc.2023.109767 · 2023 · External reference
