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References from Exploring traditional Chinese medicine to enhance the efficacy and reduce toxicity of immunotherapy for non-small cell lung cancer from the perspective of “spleen deficiency”: a trial protocol for mechanism and clinical evidence. Local targets link to admitted publications; unresolved targets remain external evidence.
Cancer statistics, 2026
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Addressing clinical needs in NSCLC immunotherapy: mechanisms of resistance and promising combination strategies
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Efficacy and safety of neoadjuvant immunotherapy plus chemotherapy followed by adjuvant immunotherapy in resectable non-small cell lung cancer: a meta-analysis of phase 3 clinical trials
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Resistance to PD-1/PD-L1 immune checkpoint blockade in advanced non-small cell lung cancer
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Acquired resistance to immunotherapy by physical barriers with cancer cell-expressing collagens in non-small cell lung cancer
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Traditional Chinese medicine in the era of immune checkpoint inhibitor: theory, development, and future directions
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A bibliometric and visualization analysis of the role of traditional Chinese medicine in cancer immunotherapy
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Active ingredients of traditional Chinese medicine for enhancing the effect of tumor immunotherapy
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Traditional Chinese medicine enhances the effectiveness of immune checkpoint inhibitors in tumor treatment: a mechanism discussion
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Roles of tissue-resident immune cells in immunotherapy of non-small cell lung cancer
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Evaluation of efficacy, safety and underlying mechanism on traditional Chinese medicine as synergistic agents for cancer immunotherapy: a preclinical systematic review and meta-analysis
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The effectiveness of traditional Chinese medicine in treating Malignancies via regulatory cell death pathways and the tumor immune microenvironment: a review of recent advances
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The traditional Chinese medicine and non-small cell lung cancer: from a gut microbiome perspective
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Effect of Jianpi Guchang recipe on intestinal inflammatory response after chemotherapy in intestinal carcinoma mice by enhancing abundanceof short-chain fatty acid producing bacteria
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Traditional Chinese medicine for cancer treatment
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Tumor-associated macrophages in tumor progression and the role of traditional Chinese medicine in regulating TAMs to enhance antitumor effects
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Targeted modulation of myeloid-derived suppressor cells in the tumor microenvironment: implications for cancer therapy
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The role of metabolic reprogramming in cancer metastasis and potential mechanism of traditional Chinese medicine intervention
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Applications of traditional Chinese medicine in cancer immunotherapy via gut microbiota modulation: current status, mechanisms, challenges and perspectives
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Traditional Chinese medicine (TCM) enhances the therapeutic efficiency of a gemcitabine-loaded injectable hydrogel on postoperative breast cancer through modulating the microenvironment
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Immunometabolism at the service of traditional Chinese medicine
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Traditional Chinese medicines for non-small cell lung cancer: therapies and mechanisms
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Traditional Chinese medicine in lung cancer treatment
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Role of traditional Chinese medicine in lung cancer management: a review
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Total ginsenoside wild ginseng root improves spleen qi deficiency by regulating intestinal microbes and flora metabolites
10.1016/j.arabjc.2023.105232 · 2023 · External reference
Gut dysbiosis and intestinal barrier dysfunction: potential explanation for early-onset colorectal cancer
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Clinical efficacy and gut microbiota regulating-related effect of Si-Jun-Zi decoction in postoperative non-small cell lung cancer patients: a prospective observational study
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Sijunzi decoction alleviates inflammation and intestinal epithelial barrier damage and modulates the gut microbiota in ulcerative colitis mice
10.3389/fphar.2024.1360972 · 2024 · External reference
Deep-fried Atractylodes lancea rhizome alleviates spleen deficiency diarrhea-induced short-chain fatty acid metabolic disorder in mice by remodeling the intestinal flora
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Exploring the relationship between intestinal microbiota and immune checkpoint inhibitors in the treatment of non-small cell lung cancer: insights from the "lung and large intestine stand in exterior-interior relationship" theory
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Yangyin Fuzheng Jiedu prescription exerts anti-tumor immunity in hepatocellular carcinoma by alleviating exhausted T cells
10.1016/j.phymed.2021.153722 · 2021 · External reference
Polysaccharides from Astragalus membranaceus elicit T cell immunity by activation of human peripheral blood dendritic cells
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Ginsenoside Rg3 inhibits angiogenesis in gastric precancerous lesions through downregulation of Glut1 and Glut4
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Network medicine-based strategy identifies maprotiline as a repurposable drug by inhibiting PD-L1 expression via targeting SPOP in cancer
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GEMap: a comprehensive gene essentiality map for drug discovery
10.1016/j.apsb.2026.02.004 · 2026 · External reference
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10.1016/j.apsb.2024.08.017 · 2025 · External reference
COIMMR: a computational framework to reveal the contribution of herbal ingredients against human cancer via immune microenvironment and metabolic reprogramming
10.1093/bib/bbad346 · 2023 · External reference
Tailoring traditional Chinese medicine in cancer therapy
10.1186/s12943-024-02213-6 · 2025 · External reference
The interactions between traditional Chinese medicine and gut microbiota in cancers: current status and future perspectives
10.1016/j.phrs.2024.107148 · 2024 · External reference
Exploring the potential use of Chinese herbs in regulating the inflammatory microenvironment of tumours based on the concept of 'state-target identification and treatment': a scooping review
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