References

Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

10.3322/caac.21834 · 2024 · External reference

Unresolved reference

External reference

Pancreatic cancer

10.1016/s0140-6736(20)30974-0 · 2020 · External reference

Survival benefit of resection surgery for pancreatic ductal adenocarcinoma with liver metastases: A propensity score-matched SEER database analysis

10.3390/cancers14010057 · 2021 · External reference

Surgical treatment of synchronous liver-only oligometastatic pancreatic adenocarcinoma: a systematic review and meta-analysis of long-term outcomes

10.1097/js9.0000000000002338 · 2025 · External reference

Carbohydrate antigen 19-9 is a prognostic and predictive biomarker in patients with advanced pancreatic cancer who receive gemcitabine-containing chemotherapy: a pooled analysis of 6 prospective trials

10.1002/cncr.27734 · 2013 · External reference

Developments in metastatic pancreatic cancer: is gemcitabine still the standard

10.3748/wjg.v18.i8.736 · 2012 · External reference

NALIRIFOX, FOLFIRINOX, and gemcitabine with nab-paclitaxel as first-line chemotherapy for metastatic pancreatic cancer: a systematic review and meta-analysis

10.1001/jamanetworkopen.2023.50756 · 2024 · External reference

Immune remodeling of liver metastases: From molecular mechanisms to therapeutic strategies

10.1016/j.bbcan.2026.189618 · 2026 · External reference

The immunobiology of pancreatic cancer metastasis: premetastatic niche formation, organ-specific immune landscapes, and therapeutic opportunities

10.1007/s10555-026-10334-1 · 2026 · External reference

Looking beyond checkpoint inhibitor monotherapy: Uncovering new frontiers for pancreatic cancer immunotherapy

10.1158/1535-7163.mct-24-0311 · 2025 · External reference

Second-line treatment of pancreatic adenocarcinoma: Shedding light on new opportunities and key talking points from clinical trials

10.2147/ceg.s390655 · 2024 · External reference

Pancreatic cancer is feeling the heat

10.1136/jitc-2024-010124 · 2024 · External reference

Biological functions and therapeutic potential of NAD+ metabolism in gynecological cancers

10.3390/cancers16173085 · 2024 · External reference

Regulating the regulators via targeting CD38 in the tumor microenvironment

10.3389/fimmu.2026.1745988 · 2026 · External reference

Why is the tumor microenvironment disordered by NADH/NAD+ imbalance and how can we intervene

10.1016/j.redox.2026.104145 · 2026 · External reference

NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling

10.1038/s41586-019-1150-2 · 2019 · External reference

Combined targeting of NAD biosynthesis and the NAD-dependent transcription factor C-terminal binding protein as a promising novel therapy for pancreatic cancer

10.1158/2767-9764.crc-22-0521 · 2023 · External reference

Targeting of NAD metabolism in pancreatic cancer cells: potential novel therapy for pancreatic tumors

10.1158/1078-0432.ccr-13-0150 · 2014 · External reference

Possible mechanisms of cancer prevention by nicotinamide

10.1111/bph.15096 · 2021 · External reference

Role of nicotinamide in the pathogenesis of actinic keratosis: Implications for NAD+/SIRT1 pathway

10.3390/biom14121512 · 2024 · External reference

Nicotinamide for secondary keratinocyte carcinoma prevention in solid organ transplant recipients

10.1007/s00403-025-04296-7 · 2025 · External reference

Nicotinamide for skin cancer chemoprevention: The jury was out and still is

10.1007/s40257-025-01005-y · 2026 · External reference

Nicotinamide in type 1 diabetes. Mechanism of action revisited

1999 · External reference

Quantitative studies of inhibitors of ADP-ribosylation in vitro and in vivo

10.1016/s0021-9258(18)83741-3 · 1989 · External reference

Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin

10.1038/6535 · 1999 · External reference

Novel insights into PARPs in gene expression: regulation of RNA metabolism

10.1007/s00018-019-03120-6 · 2019 · External reference

Safety of high-dose nicotinamide: a review

10.1007/s001250051536 · 2000 · External reference

The Deutsche Nicotinamide Intervention Study: an attempt to prevent type 1 diabetes. DENIS Group

10.2337/diabetes.47.6.980 · 1998 · External reference

PARPs and PARP inhibitors: molecular mechanisms and clinical applications

10.1186/s43556-025-00385-1 · 2025 · External reference

Clinical applications of PARP inhibitors in breast, ovarian, and prostate cancer: current insights and future directions

2026 · External reference

Imaging therapeutic PARP inhibition in vivo through bioorthogonally developed companion imaging agents

10.1593/neo.12414 · 2012 · External reference

Pharmacokinetics and pharmacodynamics of PARP inhibitors in oncology

10.1007/s40262-022-01167-6 · 2022 · External reference

The prognostic impact of HER2 genetic and protein expression in pancreatic carcinoma-HER2 protein and gene in pancreatic cancer

10.3390/diagnostics11040653 · 2021 · External reference

P53 function status correlates with overall survival in patients with resected pancreatic cancer

10.1002/jso.70060 · 2025 · External reference

Real-time targeted genome profile analysis of pancreatic ductal adenocarcinomas identifies genetic alterations that might be targeted with existing drugs or used as biomarkers

10.1053/j.gastro.2019.02.037 · 2019 · External reference

Molecular characterization of KRAS wild-type tumors in patients with pancreatic adenocarcinoma

10.1158/1078-0432.ccr-21-3581 · 2022 · External reference

Genomic landscape of clinically advanced KRAS wild-type pancreatic ductal adenocarcinoma

10.3389/fonc.2023.1169586 · 2023 · External reference

Characteristics of KRAS WT pancreatic adenocarcinomas: results of a large French multicentric cohort

10.1177/17588359251339939 · 2025 · External reference

Epigenetic dysregulation in pancreatic cancer: emerging biomarkers and clinical applications

10.3389/freae.2025.1723159 · 2025 · External reference

Radiofrequency ablation of liver metastases in a patient with pancreatic cancer and long-term survival: A case report

10.12998/wjcc.v13.i20.100169 · 2025 · External reference

Sustained complete remission after radiofrequency ablation for liver oligometastasis from pancreatic cancer despite persistent carbohydrate antigen 19-9 elevation: A case report

10.70352/scrj.cr.26-0003 · 2026 · External reference

Pancreatic cancer with liver metastasis maintaining complete response with gemcitabine monotherapy: A case report

10.3892/ol.2024.14503 · 2024 · External reference

Long-term complete remission of two patients with synchronous liver metastasis from pancreatic cancer and underlying BRCA-2 mutation

10.51821/87.4.11787 · 2024 · External reference