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MELK is a novel therapeutic target in high-risk neuroblastoma

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Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia

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Maternal embryonic leucine zipper kinase serves as a poor prognosis marker and therapeutic target in gastric cancer

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Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer

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Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells

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Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer

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Drug and apoptosis resistance in cancer stem cells: a puzzle with many pieces

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MELK inhibition effectively suppresses growth of glioblastoma and cancer stem-like cells by blocking AKT and FOXM1 pathways

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Therapeutic landscape of FOXM1 in triple-negative breast cancer and aggressive solid cancers

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P53 and the ultraviolet radiation-induced skin response: Finding the light in the darkness of triggered carcinogenesis

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Regulation of cell cycle progression by growth factor-induced cell signaling

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Differential effects of overexpression of wild type and kinase-dead MELK in fibroblasts and keratinocytes, potential implications for skin wound healing and cancer

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Targeting the DNA damage response for cancer therapy

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MELK as a mediator of stemness and metastasis in aggressive subtypes of breast cancer

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Identification of IL11RA and MELK amplification in gastric cancer by comprehensive genomic profiling of gastric cancer cell lines

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High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo

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Identification of prognostic genes in kidney renal clear cell carcinoma by RNA-seq data analysis

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Maternal embryonic leucine zipper kinase: A novel biomarker and a potential therapeutic target in lung adenocarcinoma

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Corosolic acid induces cell cycle arrest and cell apoptosis in human retinoblastoma Y-79 cells via disruption of MELK-FoxM1 signaling

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Cyclosporin A inhibits prostate cancer growth through suppression of E2F8 transcription factor in a MELK-dependent manner

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M-phase MELK activity is regulated by MPF and MAPK

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Cortical localization of maternal embryonic leucine zipper kinase (MELK) implicated in cytokinesis in early Xenopus embryos

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The roles of TOPK in tumorigenesis and development: Structure, mechanisms, pathways, and therapeutic implications

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Up-regulation of MELK by E2F1 promotes the proliferation in cervical cancer cells

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MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells

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CRISPR/Cas9 mutagenesis invalidates a putative cancer dependency targeted in on-going clinical trials

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MELK is not necessary for the proliferation of basal-like breast cancer cells

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MELK expression correlates with tumor mitotic activity but is not required for cancer growth

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