Research graph
References from Role of serum amyloid A in Mycoplasma pneumoniae pneumonia and related respiratory diseases. Local targets link to admitted publications; unresolved targets remain external evidence.
Mycoplasma pneumoniae from the respiratory tract and beyond
10.1128/cmr.00114-16 · 2017 · External reference
Mycoplasma pneumoniae among children hospitalized with community-acquired pneumonia
10.1093/cid/ciy419 · 2019 · External reference
Circulating antibody-secreting cell response during Mycoplasma pneumoniae childhood pneumonia
10.1093/infdis/jiaa062 · 2020 · External reference
The combination of initial markers to predict refractory Mycoplasma pneumoniae pneumonia in Chinese children: a case control study
10.1186/s12931-020-01577-9 · 2021 · External reference
Exhausted and apoptotic BALF T cells in proinflammatory airway milieu at acute phase of severe Mycoplasma pneumoniae pneumonia in children
10.3389/fimmu.2021.760488 · 2022 · External reference
High prevalence of macrolide resistance in Mycoplasma pneumoniae isolates from adult and adolescent patients with respiratory tract infection in China
10.1086/653535 · 2010 · External reference
Mycoplasma pneumoniae: current knowledge on macrolide resistance and treatment
10.3389/fmicb.2016.00974 · 2016 · External reference
ADP-ribosylating and vacuolating cytotoxin of Mycoplasma pneumoniae represents unique virulence determinant among bacterial pathogens
10.1073/pnas.0510644103 · 2006 · External reference
Identification and characterization of human surfactant protein A binding protein of Mycoplasma pneumoniae
10.1128/iai.73.5.2828-2834.2005 · 2005 · External reference
ADP-Ribosylation of NLRP3 by Mycoplasma pneumoniae CARDS toxin regulates inflammasome activity
10.1128/mbio.02186-14 · 2014 · External reference
Nlrp3 is a critical regulator of inflammation and innate immune cell response during Mycoplasma pneumoniae infection
10.1128/iai.00548-17 · 2018 · External reference
Serum amyloid A – a review
10.1186/s10020-018-0047-0 · 2018 · External reference
Structure and expression of different Serum amyloid A (SAA) variants and their concentration-dependent functions during host insults
10.2174/0929867323666160418114600 · 2016 · External reference
Serum amyloid A1: structure, function and gene polymorphism
10.1016/j.gene.2016.02.044 · 2016 · External reference
Emerging functions of serum amyloid A in inflammation
10.1189/jlb.3vmr0315-080r · 2015 · External reference
Expression levels and significance of CARDS TX, TNF-α and SAA in serum and bronchoalveolar lavage fluid of children with refractory Mycoplasma pneumoniae pneumonia
2023 · External reference
Predictive value of combined detection of serum SAA, YKL-40 and SP-A in children with refractory Mycoplasma pneumoniae pneumonia
2023 · External reference
Value of serum SAA, HC-gp39 and SF detection in prognostic assessment of children with refractory Mycoplasma pneumoniae pneumonia
2021 · External reference
Acute-phase serum amyloid A: perspectives on its physiological and pathological roles
10.3109/13506129.2011.654294 · 2012 · External reference
Role of Serum amyloid A in abdominal aortic aneurysm and related cardiovascular diseases
10.3390/biom11121883 · 2021 · External reference
Serum amyloid A is an exchangeable apolipoprotein
10.1161/atvbaha.118.310979 · 2018 · External reference
Thermal transitions in serum amyloid A in solution and on the lipid: implications for structure and stability of acute-phase HDL
10.1194/jlr.m059162 · 2015 · External reference
Immune response plays a role in Mycoplasma pneumoniae pneumonia
10.3389/fimmu.2023.1189647 · 2023 · External reference
Levels and diagnostic value of ficolin-3, STAT3, TLR4 and NF-κB in children with Mycoplasma pneumoniae infection
2025 · External reference
Extracellular vesicles released from macrophages infected with Mycoplasma pneumoniae stimulate proinflammatory response via the TLR2-NF-κB/JNK signaling pathway
10.3390/ijms24108588 · 2023 · External reference
Serum amyloid A, the major vertebrate acute-phase reactant
10.1046/j.1432-1327.1999.00657.x · 1999 · External reference
Regulation of serum amyloid A protein expression during the acute-phase response
10.1042/bj3340489 · 1998 · External reference
Induction of Serum amyloid A3 in mouse mammary epithelial cells stimulated with lipopolysaccharide and lipoteichoic acid
10.3390/ani11061548 · 2021 · External reference
Serum cytokine profiling reveals different immune response patterns during general and severe Mycoplasma pneumoniae pneumonia
10.3389/fimmu.2022.1088725 · 2022 · External reference
B cells oppose Mycoplasma pneumoniae vaccine enhanced disease and limit bacterial colonization of the lungs
10.1038/s41541-022-00556-z · 2022 · External reference
LncRNA MALAT1 affects Mycoplasma pneumoniae pneumonia via NF-κB regulation
10.3389/fcell.2020.563693 · 2020 · External reference
Serum amyloid A1 induces classically activated macrophages: a role for enhanced fibril formation
10.3389/fimmu.2021.691155 · 2021 · External reference
SAA does not induce cytokine production in physiological conditions
10.1016/j.cyto.2012.10.019 · 2013 · External reference
Functional interactions between recombinant Serum amyloid A1 (SAA1) and chemokines in leukocyte recruitment
10.3390/ijms26052258 · 2025 · External reference
Serum amyloid A is a soluble pattern recognition receptor that drives type 2 immunity
10.1038/s41590-020-0698-1 · 2020 · External reference
Correlations between serum amyloid A protein and C-reactive protein in infectious diseases
10.1080/00365510310001636 · 2003 · External reference
Serum amyloid A-containing human high density lipoprotein 3. Density, size, and apolipoprotein composition
10.1016/s0021-9258(18)67562-3 · 1986 · External reference
Functionally defective high-density lipoprotein: a new therapeutic target at the crossroads of dyslipidemia, inflammation, and atherosclerosis
10.1124/pr.58.3.1 · 2006 · External reference
SAA-only HDL formed during the acute phase response in apoA-I-deficient mice
10.1016/s0022-2275(20)33513-6 · 1999 · External reference
Anti-inflammatory HDL becomes pro-inflammatory during the acute phase response. Loss of protective effect of HDL against LDL oxidation in aortic wall cell cocultures
10.1172/jci118345 · 1995 · External reference
Inflammatory/antiinflammatory properties of high-density lipoprotein distinguish patients from control subjects better than high-density lipoprotein cholesterol levels and are favorably affected by simvastatin treatment
10.1161/01.cir.0000103624.14436.4b · 2003 · External reference
Relationship of SAA, CRP, NLR and PLR levels with disease progression and humoral immunity in children with Mycoplasma pneumoniae infection
2024 · External reference
HDL remodeling during the acute phase response
10.1161/atvbaha.108.178681 · 2009 · External reference
Effects of serum amyloid A on the structure and antioxidant ability of high-density lipoprotein
10.1042/bsr20160075 · 2016 · External reference
Surfactant lipids at the host–environment interface. Metabolic sensors, suppressors, and effectors of inflammatory lung disease
10.1165/rcmb.2016-0011ps · 2016 · External reference
Serum amyloid A–containing HDL binds adipocyte-derived versican and macrophage-derived biglycan, reducing its antiinflammatory properties
10.1172/jci.insight.142635 · 2020 · External reference
A seven-transmembrane, G protein-coupled receptor, FPRL1, mediates the chemotactic activity of serum amyloid A for human phagocytic cells
10.1084/jem.189.2.395 · 1999 · External reference
Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRL1/LXA4R
10.1182/blood-2002-05-1431 · 2003 · External reference
Serum amyloid A-induced mRNA expression and release of tumor necrosis factor-alpha (TNF-α) in human neutrophils
10.1016/j.imlet.2003.09.011 · 2004 · External reference
Relationship between neutrophil CD162, CXCR2 and CXCR4 expression and Mycoplasma pneumoniae infection in children
2022 · External reference
Serum amyloid A-dependent inflammasome activation and acute injury in a mouse model of experimental stroke
10.3390/ijms27052281 · 2026 · External reference
Risk factors analysis of airway mucus plugs in community-acquired refractory mycoplasma pneumoniae pneumonia: a case-control study
10.1186/s13052-025-02071-y · 2025 · External reference
Investigation of T lymphocyte subsets in children with Mycoplasma pneumoniae pneumonia
10.1007/s12026-024-09576-4 · 2025 · External reference
Alx/FPR2 contributes to Serum amyloid A-induced lung neutrophil recruitment following acute ozone exposure
10.1096/fj.202402865r · 2025 · External reference
Is serum amyloid A an endogenous TLR4 agonist?
10.1189/jlb.0407203 · 2008 · External reference
Cutting edge: tLR2 is a functional receptor for acute-phase serum amyloid A
10.4049/jimmunol.181.1.22 · 2008 · External reference
The functional response of human monocyte-derived macrophages to serum amyloid A and Mycobacterium tuberculosis infection
10.3389/fimmu.2023.1238132 · 2023 · External reference
Serum amyloid A (SAA) activates the NLRP3 inflammasome and promotes TH17 allergic asthma in mice
10.4049/jimmunol.1100500 · 2011 · External reference
Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway
10.4049/jimmunol.1002843 · 2011 · External reference
Role of SAA1 in mediating renal fibrosis through TLR4-dependent NF-κB activation
10.1186/s12882-025-04438-z · 2025 · External reference
Balancing inflammation: the specific roles of serum amyloid A proteins in sterile and infectious diseases
10.3389/fimmu.2025.1544085 · 2025 · External reference
Serum amyloid A: a double-edged sword in health and disease
10.3390/ijms26104528 · 2025 · External reference
Matrix metalloproteinase-9-generated COOH-, but not NH2-terminal fragments of Serum amyloid A1 retain potentiating activity in neutrophil migration to CXCL8, with loss of direct chemotactic and cytokine-inducing capacity
10.3389/fimmu.2018.01081 · 2018 · External reference
Mouse bone marrow mesenchymal stem cells inhibit sepsis-induced lung injury in mice via exosomal SAA1
10.1021/acs.molpharmaceut.2c00542 · 2022 · External reference
Pathogen evasion of humoral innate immunity: coping with C-reactive protein and Serum amyloid A
10.3390/ijms27021072 · 2026 · External reference
Mycobacterium tuberculosis binds human Serum amyloid A, and the interaction modulates the colonization of human macrophages and the transcriptional response of the pathogen
10.3390/cells10051264 · 2021 · External reference
Serum amyloid A proteins reduce bone mass during mycobacterial infections
10.3389/fimmu.2023.1168607 · 2023 · External reference
Serum amyloid A exhibits pH dependent antibacterial action and contributes to host defense against Staphylococcus aureus cutaneous infection
10.1074/jbc.ra119.010626 · 2020 · External reference
Diagnostic value of serum amyloid A in children with Mycoplasma pneumoniae pneumonia
10.19347/j.cnki.2096-1413.202203030 · 2022 · External reference
Changes and significance of serum SAA, CRP and PCT levels in children with Mycoplasma pneumoniae pneumonia
2020 · External reference
Role of serum amyloid A detection in Mycoplasma pneumoniae pneumonia
2022 · External reference
Unresolved reference
External reference
Construction of a prediction model for poor prognosis in children with refractory Mycoplasma pneumoniae pneumonia based on serum SAA/CRP and RBP levels
2026 · External reference
Relationship of serum amyloid A, eotaxin and pentraxin 3 levels with pulmonary function indicators, Mycoplasma pneumoniae DNA levels and prognosis in children with Mycoplasma pneumoniae pneumonia
2025 · External reference
Predictive value of combined detection of SAA/hs-CRP, NLR and PCT in prognosis of children with Mycoplasma pneumoniae pneumonia
2024 · External reference
Construction of an early warning model for Mycoplasma pneumoniae pneumonia complicated with pleural effusion in children based on serum inflammatory markers
2024 · External reference
Biological functions of IL-17-producing cells in mycoplasma respiratory infection
10.1111/imm.13346 · 2021 · External reference
Overexpression of hepatic serum amyloid A1 in mice increases IL-17-producing innate immune cells and decreases bone density
10.1016/j.jbc.2021.100595 · 2021 · External reference
Predictive role of IL-17A in children with refractory Mycoplasma pneumoniae pneumonia
2023 · External reference
Serum IL-17A and IL-6 in paediatric Mycoplasma pneumoniae pneumonia: implications for different endotypes
10.1080/22221751.2024.2324078 · 2024 · External reference
Elevated Serum amyloid A levels contribute to increased platelet adhesion in COVID-19 patients
10.3390/ijms232214243 · 2022 · External reference
Serum amyloid A aggravates lipopolysaccharide-induced injury of BEAS-2B cells by activating toll-like receptor 2/activator protein-1 signaling
10.1166/jbt.2021.2557 · 2021 · External reference
Immune dysregulation in Mycoplasma pneumoniae pneumonia: mechanistic controversies and clinical translation from inflammatory dysregulation and immune evasion to chronic injury
10.3389/fimmu.2026.1724496 · 2026 · External reference
Serum amyloid A3 aggravates bleomycin-induced pulmonary fibrosis through krüppel-like factor 6-dependent interlukin-36α expression
10.1038/s41401-025-01596-6 · 2025 · External reference
From immune activation to disease progression: unraveling the complex role of Serum amyloid A proteins
10.1016/j.cytogfr.2025.03.003 · 2025 · External reference
Changes in the levels of the Serum markers Serum amyloid A and immunoglobulin M in children with Mycoplasma pneumoniae infection complicated with asthma and their clinical significance
10.1615/critreveukaryotgeneexpr.2025056739 · 2025 · External reference
Serum amyloid A in patients with idiopathic pulmonary fibrosis
10.1016/j.resinv.2019.03.010 · 2019 · External reference
Specificity of serum amyloid A as a biomarker of idiopathic pulmonary fibrosis
10.1111/imj.15113 · 2020 · External reference
Serum amyloid A: a potential biomarker of lung disorders
10.1016/j.resinv.2019.09.005 · 2020 · External reference
Biomarkers for early diagnosis of idiopathic pulmonary fibrosis: a systematic review
10.1007/s40846-024-00909-0 · 2024 · External reference
Role of Serum amyloid A as a biomarker for predicting the severity and prognosis of COVID-19
10.1155/2022/6336556 · 2022 · External reference
Association between serum amyloid A levels and predicting disease severity in COVID-19 patients: a systematic review and meta-analysis
10.26355/eurrev_202107_26255 · 2021 · External reference
Interferon-γ-induced protein 10 (IP-10) and serum amyloid A (SAA) are excellent biomarkers for the prediction of COVID-19 progression and severity
10.1016/j.lfs.2021.119019 · 2021 · External reference
Serum amyloid A protein has been undervalued as a biomarker of COVID-19
10.1002/dmrr.3376 · 2021 · External reference
The silencing of SAA1 suppresses pneumonia progression via modulating the NLR signaling pathway
10.21037/atm-22-4013 · 2022 · External reference
Clinical significance of serum NLR, SAA and procalcitonin in patients with ARDS and their relationship with prognosis
2022 · External reference
Clinical usefulness of Serum lactate dehydrogenase levels in Mycoplasma pneumoniae pneumonia in children
10.1007/s12098-022-04205-0 · 2022 · External reference
Clinical characteristics of mycoplasma pneumoniae pneumonia in children with 23 S rRNA mutations in domain V and exploration of the timing of glucocorticoid therapy
10.1186/s12879-025-11584-0 · 2025 · External reference
Mechanisms of corticosteroid resistance in type 17 asthma
10.4049/jimmunol.2200288 · 2022 · External reference
Acute-serum amyloid A and A-SAA-derived peptides as formyl peptide receptor (FPR) 2 ligands
10.3389/fendo.2023.1119227 · 2023 · External reference
Small peptides for inhibiting Serum amyloid A aggregation
10.1021/acsmedchemlett.1c00456 · 2021 · External reference
Serum amyloid A3 deficiency impairs in vitro and in vivo adipocyte differentiation
10.1080/21623945.2021.1916220 · 2021 · External reference
Relationship between serum amyloid A and disease severity of Mycoplasma pneumoniae pneumonia in children
10.11675/j.issn.0253-4304.2021.03.17 · 2021 · External reference
Diagnostic value of serum amyloid A in Mycoplasma pneumoniae pneumonia
10.20047/j.issn.1673-7210.2020.07.042 · 2020 · External reference
Serum amyloid A promotes emphysema by triggering the reciprocal activation of neutrophils and ILC3s
10.1002/ctm2.637 · 2021 · External reference