Research graph
References from Inflammatory biomarkers in pediatric PFAPA syndrome: a systematic review. Local targets link to admitted publications; unresolved targets remain external evidence.
Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome: a review
10.1016/j.wjorl.2021.05.004 · 2021 · External reference
PFAPA Syndrome: a review on treatment and outcome
10.1186/s12969-016-0101-9 · 2016 · External reference
Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome: main features and an algorithm for clinical practice
10.1007/s00296-019-04257-0 · 2019 · External reference
Syndrome of periodic fever, pharyngitis, and aphthous stomatitis
10.1016/s0022-3476(87)80285-8 · 1987 · External reference
Periodic fever syndrome in children
10.1016/s0022-3476(99)70321-5 · 1999 · External reference
Epidemiology and clinical features of PFAPA: a retrospective cohort study of 336 patients in western Sweden
10.1186/s12969-022-00737-z · 2022 · External reference
PFAPA Syndrome—an important differential diagnosis in children with recurrent fever
2019 · External reference
Long-Term follow-up of children with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome
10.1016/j.jpeds.2011.06.004 · 2011 · External reference
Diagnostic and therapeutic difficulties in PFAPA: a case report
10.15557/pimr.2022.0056 · 2022 · External reference
Clinical features and diagnosis of PFAPA syndrome: approach of the primary care physician
10.5114/polp.2021.109301 · 2021 · External reference
Periodic fever, aphthous stomatitis, pharyngitis, and adenopathy syndrome: clinical characteristics and outcome
10.1016/s0022-3476(99)70335-5 · 1999 · External reference
Classification criteria for autoinflammatory recurrent fevers
10.1136/annrheumdis-2019-215048 · 2019 · External reference
Eurofever project the eurofever project: towards better care for autoinflammatory diseases
10.1007/s00431-011-1411-z · 2011 · External reference
PFAPA Syndrome: with regard to a case
10.1016/s0301-0546(03)79185-x · 2003 · External reference
Paediatric rheumatology international trials organisation (PRINTO) and the AIDs delphi study participants consensus proposal for taxonomy and definition of the autoinflammatory diseases (AIDs): a delphi study
10.1136/annrheumdis-2017-212515 · 2018 · External reference
The clinical chameleon of autoinflammatory diseases in children
10.3390/cells11142231 · 2022 · External reference
Autoinflammatory syndromes behind the scenes of recurrent fevers in children
2009 · External reference
Inflammasome priming in Sterile inflammatory disease
10.1016/j.molmed.2016.12.007 · 2017 · External reference
Increased prevalence of NLRP3 Q703 K variant among patients with autoinflammatory diseases: an international multicentric study
10.3389/fimmu.2020.00877 · 2020 · External reference
The NLRP3 and pyrin inflammasomes: implications in the pathophysiology of autoinflammatory diseases
10.3389/fimmu.2017.00043 · 2017 · External reference
Periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis syndrome is linked to dysregulated monocyte IL-1β production
10.1016/j.jaci.2012.07.043 · 2013 · External reference
Increased intracellular oxygen radical production in neutrophils during febrile episodes of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome
10.1002/art.38134 · 2013 · External reference
Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) is a disorder of innate immunity and Th1 activation responsive to IL-1 blockade
10.1073/pnas.1103681108 · 2011 · External reference
Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome: a review of the pathogenesis
10.1007/s11926-016-0567-y · 2016 · External reference
New insights on multigenic autoinflammatory diseases
10.1177/1759720x221117880 · 2022 · External reference
Undifferentiated recurrent fevers in pediatrics are clinically distinct from PFAPA syndrome but retain an IL-1 signature
10.1016/j.clim.2021.108697 · 2021 · External reference
Immune dysregulation in the tonsillar microenvironment of periodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome
10.1007/s10875-019-00724-2 · 2020 · External reference
C-Reactive protein in the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome
10.1111/j.1651-2227.2007.00499.x · 2007 · External reference
Serum amyloid A as predictive factor in PFAPA syndrome attack
10.1016/j.medcli.2025.107244 · 2026 · External reference
MRP8 And MRP14, phagocyte-specific danger signals, are sensitive biomarkers of disease activity in cryopyrin-associated periodic syndromes
10.1136/ard.2011.152496 · 2011 · External reference
The etiological Spectrum of pediatric FUO and clinical management of PFAPA/SURF: a ten-year retrospective study
10.3389/fimmu.2026.1791904 · 2026 · External reference
Rayyan—a web and Mobile app for systematic reviews
10.1186/s13643-016-0384-4 · 2016 · External reference
Differential cytokine profiles in pediatric patients with PFAPA syndrome and recurrent tonsillitis
10.2152/jmi.68.38 · 2021 · External reference
Cytokine profiles and laboratory parameters as indicators to distinguish children with PFAPA and bacterial infection
10.3389/fimmu.2026.1683221 · 2026 · External reference
Clinical features and new diagnostic criteria for the syndrome of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis
10.1111/1756-185x.13610 · 2019 · External reference
Epidemiology and clinical course of PFAPA syndrome in the pediatric population-single center study
10.1186/s12887-026-07134-5 · 2026 · External reference
QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies
10.7326/0003-4819-155-8-201110180-00009 · 2011 · External reference
PFAPA Syndrome: clinical, laboratory and therapeutic features in a single-centre cohort
10.2147/ijgm.s373942 · 2022 · External reference
Diagnostic performance of routine blood parameters in periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome
10.1002/jcla.24934 · 2023 · External reference
The use of ketotifen as long-term anti-inflammatory prophylaxis in children with PFAPA syndrome
10.3389/fimmu.2023.1302875 · 2023 · External reference
Interleukin-4 and interferon-γ orchestrate an epithelial polarization in the airways
10.1038/mi.2015.110 · 2016 · External reference
The type I interferonopathies: 10 years on
10.1038/s41577-021-00633-9 · 2022 · External reference
IL-1 Blockade in autoinflammatory syndromes
10.1146/annurev-med-061512-150641 · 2014 · External reference
Unresolved reference
2026 · External reference
Unresolved reference
2026 · External reference
