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References from Protein kinase C-λ drives third-degree burn-induced muscle wasting via STAT3-dependent catabolic pathways. Local targets link to admitted publications; unresolved targets remain external evidence.
The protein kinase C and protein kinase C related gene families
10.1016/0959-440x(95)80103-0 · 1995 · External reference
C188-9, a small-molecule STAT3 inhibitor, exerts an antitumor effect on head and neck squamous cell carcinoma
10.1097/cad.0000000000000783 · 2019 · External reference
PKCε as a novel promoter of skeletal muscle differentiation and regeneration
10.1016/j.yexcr.2015.09.017 · 2015 · External reference
Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes
10.1172/jci31408 · 2007 · External reference
Dietary supplementation with inulin improves burn-induced skeletal muscle atrophy by regulating gut microbiota disorders
10.1038/s41598-024-52066-8 · 2024 · External reference
Burn-induced gut microbiota dysbiosis aggravates skeletal muscle atrophy by tryptophan-kynurenine mediated AHR pathway activation
10.1002/advs.202409296 · 2025 · External reference
Drugs interfering with insulin resistance and their influence on the associated hypermetabolic state in severe burns: a narrative review
10.3390/ijms22189782 · 2021 · External reference
Increased protein kinase C theta in skeletal muscle of diabetic patients
10.1053/meta.2001.22512 · 2001 · External reference
A novel PKC-ι inhibitor abrogates cell proliferation and induces apoptosis in neuroblastoma
10.1016/j.biocel.2011.02.002 · 2011 · External reference
Burn injury
10.1038/s41572-020-0145-5 · 2020 · External reference
Protein kinase C ι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities
10.1016/j.celrep.2021.110054 · 2021 · External reference
The role of bone secreted factors in burn-induced muscle cachexia
10.1007/s11914-018-0416-1 · 2018 · External reference
Burn-induced hypermetabolism and skeletal muscle dysfunction
10.1152/ajpcell.00106.2021 · 2021 · External reference
The interruption of PKC-ι signaling and TRAIL combination therapy against glioblastoma cells
10.1007/s11064-014-1361-8 · 2014 · External reference
C188-9, a specific inhibitor of STAT3 signaling, prevents thermal burn-induced skeletal muscle wasting in mice
10.3389/fphar.2022.1031906 · 2022 · External reference
What is the role of puberty in the development of islet autoimmunity and progression to type 1 diabetes?
10.1007/s10654-023-01002-7 · 2023 · External reference
Interplay between protein kinase C epsilon and reactive oxygen species during myogenic differentiation
10.3390/cells12131792 · 2023 · External reference
Oncogenic PKC-ι activates vimentin during epithelial-mesenchymal transition in melanoma; a study based on PKC-ι and PKC-ζ specific inhibitors
10.1080/19336918.2018.1471323 · 2018 · External reference
The dual roles of the atypical protein kinase Cs in cancer
10.1016/j.ccell.2019.07.010 · 2019 · External reference
Protein kinase C
10.1016/0163-7258(91)90042-k · 1991 · External reference
C188-9 reduces patient-specific primary breast cancer cells proliferation at the low, clinic-relevant concentration
10.1186/s12967-024-05542-8 · 2024 · External reference