Research graph
References from Vitamin D in male reproduction: molecular mechanisms and pharmacological perspectives. Local targets link to admitted publications; unresolved targets remain external evidence.
The association between vitamin D and the components of Male fertility: a systematic review
10.3390/biomedicines11010090 · 2022 · External reference
A unique view on male infertility around the globe
10.1186/s12958-015-0032-1 · 2015 · External reference
Male oxidative stress infertility (MOSI): proposed terminology and clinical practice guidelines for management of idiopathic Male infertility
10.5534/wjmh.190055 · 2019 · External reference
Role of oxidative stress in Male infertility: an updated review
10.4103/jhrs.jhrs_150_18 · 2019 · External reference
Human sperm anatomy: ultrastructural localization of 1α,25-dihydroxyvitamin D3 receptor and its possible role in the human male gamete
10.1111/j.1469-7580.2008.00975.x · 2008 · External reference
Human male gamete endocrinology: 1alpha,25-dihydroxyvitamin D3 (1,25(OH)2D3) regulates different aspects of human sperm biology and metabolism
10.1186/1477-7827-7-140 · 2009 · External reference
The association between serum vitamin D, fertility and semen quality: a systematic review and meta-analysis
10.1016/j.ijsu.2019.09.025 · 2019 · External reference
Investigation of vitamin D levels in men with suspected infertility
10.3390/life14020273 · 2024 · External reference
Male vitamin D status and male factor infertility
10.1016/j.fertnstert.2021.06.035 · 2021 · External reference
Vitamin D alleviates lead induced renal and testicular injuries by immunomodulatory and antioxidant mechanisms in rats
10.1038/s41598-018-23258-w · 2018 · External reference
Vitamin D metabolism, mechanism of action, and clinical applications
10.1016/j.chembiol.2013.12.016 · 2014 · External reference
Vitamin D binding protein, total and free vitamin D levels in different physiological and pathophysiological conditions
10.3389/fendo.2019.00317 · 2019 · External reference
Vitamin D levels and human sperm DNA fragmentation: a prospective, cohort study
10.1186/s12610-022-00166-8 · 2022 · External reference
Vitamin D and male reproduction
10.1038/nrendo.2013.262 · 2014 · External reference
Vitamin D receptor and vitamin D metabolizing enzymes are expressed in the human male reproductive tract
10.1093/humrep/deq024 · 2010 · External reference
Vitamin D is positively associated with sperm motility and increases intracellular calcium in human spermatozoa
10.1093/humrep/der059 · 2011 · External reference
Effects of vitamin D supplementation on semen quality, reproductive hormones, and live birth rate: a randomized clinical trial
10.1210/jc.2017-01656 · 2018 · External reference
International estimates of infertility prevalence and treatment-seeking: potential need and demand for infertility medical care
10.1093/humrep/dem046 · 2007 · External reference
Vitamin D and human health: lessons from vitamin D receptor null mice
10.1210/er.2008-0004 · 2008 · External reference
Association between serum vitamin D levels and sperm DNA fragmentation index in varicocele patients: a retrospective cohort study
10.1186/s12958-025-01438-4 · 2025 · External reference
Vitamin D and Male reproduction: updated evidence based on literature review
10.3390/nu14163278 · 2022 · External reference
Vitamin D receptor gene FokI polymorphisms and tuberculosis susceptibility: a meta-analysis
10.5114/aoms.2016.60092 · 2016 · External reference
Nutrigenomics of vitamin D
10.3390/nu11030676 · 2019 · External reference
The role of TaqI, ApaI and BsmI polymorphisms of VDR gene in lumbar spine pathologies: systematic review and meta-analysis
10.1007/s00586-021-06872-7 · 2021 · External reference
Roles of vitamin D in reproductive systems and assisted reproductive technology
10.1210/endocr/bqaa023 · 2020 · External reference
Association between vitamin D receptor BsmI, FokI, and Cdx2 polymorphisms and osteoporosis risk: an updated meta-analysis
10.1042/bsr20201200 · 2020 · External reference
Vitamin D: metabolism, molecular mechanism of action, and pleiotropic effects
10.1152/physrev.00014.2015 · 2016 · External reference
Serum vitamin D content is associated with semen parameters and serum testosterone levels in men
10.4103/aja.aja_9_20 · 2021 · External reference
Vitamin D and Male fertility: an updated review
10.5534/wjmh.190057 · 2020 · External reference
BsmI, ApaI and TaqI polymorphisms in the vitamin D receptor gene (VDR) and association with lumbar spine pathologies: an Italian case-control study
10.1371/journal.pone.0155004 · 2016 · External reference
Epigenetic regulation by DNA methylation, histone modifications and chromatin remodeling complexes in controlling spermatogenesis and their dysfunction with male infertility
10.1007/s00018-025-05831-5 · 2025 · External reference
The role of vitamin D in male fertility: a focus on the testis
10.1007/s11154-017-9425-0 · 2017 · External reference
Vitamin D for the prevention of disease: an endocrine society clinical practice guideline
10.1210/clinem/dgae290 · 2024 · External reference
The association between serum vitamin D level and sperm parameters: a pilot study in a subset of Iranian infertile males
10.34172/ipp.2020.30 · 2020 · External reference
Vitamin D in disease prevention and cure-part I: an update on molecular mechanism and significance on human health
10.1007/s12291-024-01251-7 · 2025 · External reference
Linagliptin and vitamin D3 synergistically rescue testicular steroidogenesis and spermatogenesis in cisplatin-exposed rats: the crosstalk of endoplasmic reticulum stress with NF-κB/iNOS activation
10.3390/molecules27217299 · 2022 · External reference
Maternal vitamin D levels and male reproductive health: a population-based follow-up study
10.1007/s10654-023-00987-5 · 2023 · External reference
Sperm morphology, motility, and concentration in fertile and infertile men
10.1056/nejmoa003005 · 2001 · External reference
Association of 25-hydroxy-vitamin D levels with semen and hormonal parameters
10.1038/aja.2012.77 · 2012 · External reference
Genome-wide effects of chromatin on vitamin D signaling
10.1530/jme-19-0246 · 2020 · External reference
Molecular mechanisms of vitamin D action
10.1007/s00223-012-9619-0 · 2013 · External reference
Testicular synthesis and vitamin D action
10.1210/jc.2014-1690 · 2014 · External reference
Vitamin D deficiency
10.1056/nejmra070553 · 2007 · External reference
Assessment of serum vitamin D level and seminal vitamin D receptor gene methylation in a sample of Egyptian men with idiopathic infertility
10.1111/and.14172 · 2021 · External reference
Vitamin D3 regulates apoptosis and proliferation in the testis of D-galactose-induced aged rat model
10.1038/s41598-019-50679-y · 2019 · External reference
Pharmacokinetics of vitamin D toxicity
10.1093/ajcn/88.2.582s · 2008 · External reference
Oxidative stress and Male infertility: the protective role of antioxidants
10.3390/medicina59101769 · 2023 · External reference
1,25-Dihydroxyvitamin D3 stimulates cyclic vitamin D receptor/retinoid X receptor DNA-binding, co-activator recruitment, and histone acetylation in intact osteoblasts
10.1359/jbmr.041112 · 2005 · External reference
Nutri-epigenetic regulation of vitamin D-Impact on metabolism and biological functions: narrative review
10.3390/metabo15070436 · 2025 · External reference
Vitamin D supplementation stimulates germ cell proliferation in a restraint-stressed mouse
10.1016/j.reprotox.2025.109077 · 2025 · External reference
National, regional, and global trends in infertility prevalence since 1990: a systematic analysis of 277 health surveys
10.1371/journal.pmed.1001356 · 2012 · External reference
Corepressors (NCoR and SMRT) as well as coactivators are recruited to positively regulated 1α,25-dihydroxyvitamin D3-responsive genes
10.1016/j.jsbmb.2012.08.006 · 2013 · External reference
Effect of vitamin D supplementation on polycystic ovary syndrome: a meta-analysis
10.3892/etm.2020.8525 · 2020 · External reference
The effect of dietary supplements on Male infertility in terms of pregnancy, live birth, and sperm parameters: a systematic review and meta-analysis
10.3390/nu17101710 · 2025 · External reference
A stable isotope-mass spectrometric method for measuring human spermatogenesis kinetics in vivo
10.1016/s0022-5347(05)00053-4 · 2006 · External reference
Association of vitamin D receptor genetic polymorphisms with the risk of infertility: a systematic review and meta-analysis
10.1186/s12884-024-06590-0 · 2024 · External reference
Effects of hypervitaminosis C and D on spermatogenesis through CDKN1B modulation in adult male mice: biochemical and immunohistochemical studies
10.1007/s10735-025-10483-7 · 2025 · External reference
Unresolved reference
2025 · External reference
Causes of male infertility: a 9-year prospective monocentre study on 1737 patients with reduced total sperm counts
10.1093/humrep/dew284 · 2017 · External reference
Are serum levels of vitamin D associated with semen quality? Results from a cross-sectional study in young healthy men
10.1016/j.fertnstert.2010.11.002 · 2011 · External reference
Vitamins A, B, C, D, E, and K as molecular modulators: integrative roles in precision medicine, nutrigenomics, therapy, and disease prevention
10.4103/ijpmmm.ijpmmm_10_25 · 2025 · External reference
The effect of vitamin D supplementation on oxidative stress parameters: a systematic review and meta-analysis of clinical trials
10.1016/j.phrs.2018.11.011 · 2019 · External reference
Male infertility: role of vitamin D and oxidative stress markers
10.1111/and.14147 · 2021 · External reference
The controversial role of vitamin D as an antioxidant: results from randomised controlled trials
10.1017/s0954422418000197 · 2019 · External reference
Vitamin D supplementation for improving sperm parameters in infertile men: a systematic review and meta-analysis of randomized clinical trials
10.1080/2090598x.2023.2165232 · 2023 · External reference
Vitamin D receptor (VDR) gene polymorphisms modify the response to vitamin D supplementation: a systematic review and meta-analysis
10.3390/nu14020360 · 2022 · External reference
Antioxidant functions of vitamin D and CYP11A1-Derived vitamin D, tachysterol, and lumisterol metabolites: mechanisms, clinical implications, and future directions
10.3390/antiox13080996 · 2024 · External reference
The Involvement of VDR Promoter Methylation, CDX-2 VDR Polymorphism and Vitamin D Levels in Male Infertility
10.4183/aeb.2017.294 · 2017 · External reference
Common genetic determinants of vitamin D insufficiency: a genome-wide association study
10.1016/s0140-6736(10)60588-0 · 2010 · External reference
The association between vitamin D receptor FokI gene polymorphism and osteoporosis in postmenopausal women: a meta-analysis
10.1080/13697137.2020.1775806 · 2021 · External reference
The role of cells and cytokines in Male infertility induced by orchitis
10.5534/wjmh.230270 · 2024 · External reference
Vitamin D3 regulates sperm mitochondrial function essential for zebrafish reproductive ability: insights into non-classical roles†
10.1093/biolre/ioaf092 · 2025 · External reference
Vitamin D levels and risk of Male factor infertility: a mendelian randomization study
10.5534/wjmh.220109 · 2023 · External reference