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References from DepPrior: integrating CRISPR dependency predictability with multi-omics reproducibility to prioritize candidate LUAD therapeutic targets. Local targets link to admitted publications; unresolved targets remain external evidence.
Clinical application of advanced multi-omics tumor profiling: shaping precision oncology of the future
10.1016/j.ccell.2022.08.011 · 2022 · External reference
Genetic and transcriptional evolution alters cancer cell line drug response
10.1038/s41586-018-0409-3 · 2018 · External reference
Controlling the false discovery rate: a practical and powerful approach to multiple testing
10.1111/j.2517-6161.1995.tb02031.x · 1995 · External reference
Random forests
10.1023/a:1010933404324 · 2001 · External reference
XGBoost: a scalable tree boosting system
10.1145/2939672.2939785 · 2016 · External reference
Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in human non–small cell lung cancers
10.1158/2159-8290.cd-11-0046 · 2011 · External reference
Support-vector networks
10.1007/bf00994018 · 1995 · External reference
ifelines: survival analysis in Python
10.21105/joss.01317 · 2019 · External reference
Validation of a histology-independent prognostic gene signature for early-stage, non–small-cell lung cancer including stage IA patients
10.1097/jto.0000000000000042 · 2014 · External reference
Large-scale plasma proteomics comparisons through genetics and disease associations
10.1038/s41586-023-06563-x · 2023 · External reference
Greedy function approximation: a gradient boosting machine
10.1214/aos/1013203451 · 2001 · External reference
Inhibition of Myc effectively targets KRAS mutation-positive lung cancer expressing high levels of Myc
2010 · External reference
The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine
10.1186/s13073-016-0333-9 · 2016 · External reference
MYC targeting by OMO-103 in solid tumors: a phase 1 trial
10.1038/s41591-024-02805-1 · 2024 · External reference
Extremely randomized trees
10.1007/s10994-006-6226-1 · 2006 · External reference
Next-generation characterization of the cancer cell line encyclopedia
10.1038/s41586-019-1186-3 · 2019 · External reference
Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance
10.1073/pnas.1111840108 · 2011 · External reference
Proteogenomic characterization reveals therapeutic vulnerabilities in lung adenocarcinoma
10.1016/j.cell.2020.06.013 · 2020 · External reference
The cancer genome atlas research network: a sight to behold
10.1007/s12022-014-9345-4 · 2014 · External reference
We need to keep a reproducible trace of facts, predictions, and hypotheses from gene to function in the era of big data
10.1371/journal.pbio.3000999 · 2020 · External reference
Proteogenomic data and resources for pan-cancer analysis
10.1016/j.ccell.2023.06.009 · 2023 · External reference
Discovering and validating cancer genetic dependencies: approaches and pitfalls
10.1038/s41576-020-0247-7 · 2020 · External reference
New functionalities in the TCGAbiolinks package for the study and integration of cancer data from GDC and GTEx
10.1371/journal.pcbi.1006701 · 2019 · External reference
Integrated cross-study datasets of genetic dependencies in cancer
10.1038/s41467-021-21898-7 · 2021 · External reference
A comprehensive clinically informed map of dependencies in cancer cells and framework for target prioritization
10.1016/j.ccell.2023.12.016 · 2024 · External reference
Scikit-learn: machine learning in python
2011 · External reference
Alectinib versus crizotinib in untreated ALK-positive non–small-cell lung cancer
10.1056/nejmoa1704795 · 2017 · External reference
Comparison of proteomic assessment methods in multiple cohort studies
10.1002/pmic.201900278 · 2020 · External reference
Overall survival with osimertinib in untreated, EGFR-mutated advanced NSCLC
10.1056/nejmoa1913662 · 2020 · External reference
Unresolved reference
2020 · External reference
Differential association of STK11 and TP53 with KRAS mutation-associated gene expression, proliferation and immune surveillance in lung adenocarcinoma
10.1038/onc.2015.375 · 2016 · External reference
Building a translational cancer dependency map for The Cancer Genome Atlas
10.1038/s43018-024-00789-y · 2024 · External reference
Pathology of lung cancer
10.1016/j.ccm.2011.08.005 · 2011 · External reference
Defining a cancer dependency map
10.1016/j.cell.2017.06.010 · 2017 · External reference
Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types
10.1038/s41467-019-11415-2 · 2019 · External reference
Uniform genomic data analysis in the NCI Genomic Data Commons
10.1038/s41467-021-21254-9 · 2021 · External reference
Global variations in lung cancer incidence by histological subtype in 2020: a population-based study
10.1016/s1470-2045(23)00444-8 · 2023 · External reference
