References

WWP2 regulates renal fibrosis and the metabolic reprogramming of profibrotic myofibroblasts

10.1681/asn.0000000000000328 · 2024 · External reference

Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy

10.1038/ki.2009.86 · 2009 · External reference

The global burden of chronic kidney disease

10.1016/s0140-6736(19)32977-0 · 2020 · External reference

Calycosin and kidney health: a molecular perspective on its protective mechanisms

10.1007/s43440-025-00728-3 · 2025 · External reference

Inflammation in kidney repair: mechanism and therapeutic potential

10.1016/j.pharmthera.2022.108240 · 2022 · External reference

Blockade of Wnt/Beta-Catenin signaling by paricalcitol ameliorates proteinuria and kidney injury

10.1681/asn.2009121236 · 2011 · External reference

Bruceine A derivative P1 alleviates renal inflammation via Tnfrsf12a pathway in diabetic nephropathy

10.1016/j.intimp.2025.115419 · 2025 · External reference

Chronic kidney disease

10.1016/s0140-6736(25)01942-7 · 2026 · External reference

Bruceine A protects nuclear receptor 4A1 from ubiquitin-degradation to alleviate mesangial proliferative glomerulonephritis

10.1038/s41392-025-02495-2 · 2025 · External reference

Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development

10.1038/nm.3762 · 2015 · External reference

Listen to the WNT; it talks: WNT7A drives epithelial-mesenchymal cross-talk within the fibrotic niche in idiopathic pulmonary fibrosis

10.1165/rcmb.2022-0479ed · 2023 · External reference

(Pro)renin receptor is an amplifier of Wnt/Beta-Catenin signaling in kidney injury and fibrosis

10.1681/asn.2016070811 · 2017 · External reference

Bruceine A protects against diabetic kidney disease via inhibiting galectin-1

10.1016/j.kint.2022.04.020 · 2022 · External reference

Renal tubular epithelial cells response to injury in acute kidney injury

10.1016/j.ebiom.2024.105294 · 2024 · External reference

Animal models of kidney disease: challenges and perspectives

10.34067/kid.0000000000000227 · 2023 · External reference

Deficiency of mPGES-1 exacerbates renal fibrosis and inflammation in mice with unilateral ureteral obstruction

10.1152/ajprenal.00231.2016 · 2017 · External reference

Wnt9a promotes renal fibrosis by accelerating cellular senescence in tubular epithelial cells

10.1681/asn.2017050574 · 2018 · External reference

TGF-beta: the master regulator of fibrosis

10.1038/nrneph.2016.48 · 2016 · External reference

Pregnane X receptor activation alleviates renal fibrosis in mice via interacting with p53 and inhibiting the Wnt7a/beta-catenin signaling

10.1038/s41401-023-01113-7 · 2023 · External reference

Renal tubular epithelial cells: the neglected mediator of tubulointerstitial fibrosis after injury

10.1038/s41419-018-1157-x · 2018 · External reference

c-Met and NF-kappaB-dependent overexpression of Wnt7a and -7b and Pax2 promotes cystogenesis in polycystic kidney disease

10.1681/asn.2011030277 · 2012 · External reference

Diagnostic and prognostic biomarkers for tubulointerstitial fibrosis

10.1113/jp284289 · 2023 · External reference

WNT-beta-catenin signalling - a versatile player in kidney injury and repair

10.1038/s41581-020-00343-w · 2021 · External reference

Formononetin as a multifaceted modulator of renal pathology: insights into fibrotic, oxidative, inflammatory, and apoptotic pathways

10.1007/s43440-025-00801-x · 2026 · External reference

Unraveling the therapeutic potential of luteolin in renal pathology: a comprehensive pathway oriented approach

10.1007/s43440-026-00858-2 · 2026 · External reference

LTBP4 protects against renal fibrosis via mitochondrial and vascular impacts

10.1161/circresaha.123.322494 · 2023 · External reference

Bruceine A attenuates fibrogenesis and inflammation through NR2F2-regulated HMGB1 inflammatory signaling cascades in hepatic fibrosis

10.1016/j.ejphar.2024.177164 · 2025 · External reference

Quercetin alleviates chronic renal failure by targeting the PI3k/Akt pathway

10.1080/21655979.2021.1973877 · 2021 · External reference

Wnt7a-Fzd7 signalling directly activates the Akt/mTOR anabolic growth pathway in skeletal muscle

10.1038/ncb2404 · 2011 · External reference

In vivo anthelmintic activity of bruceine A and bruceine D from Brucea javanica against Dactylogyrus intermedius (Monogenea) in goldfish (Carassius auratus)

10.1016/j.vetpar.2010.11.040 · 2011 · External reference

Kokusaginine attenuates renal fibrosis by inhibiting the PI3K/AKT signaling pathway

10.1016/j.biopha.2024.116695 · 2024 · External reference

Gene signature-guided drug screening identified narciclasine as a potential therapeutic for interstitial fibrosis of the kidney

10.1016/j.kint.2025.03.021 · 2025 · External reference

TGF-beta-induced epithelial to mesenchymal transition

10.1038/cr.2009.5 · 2009 · External reference

Expression profiles and bioinformatic analysis of circular RNAs in Db/Db mice with cardiac fibrosis

10.2147/dmso.s465588 · 2024 · External reference

Mechanisms of tubulointerstitial fibrosis

10.1681/asn.2010080793 · 2010 · External reference

Bruceine A induces cell growth inhibition and apoptosis through PFKFB4/GSK3beta signaling in pancreatic cancer

10.1016/j.phrs.2021.105658 · 2021 · External reference

Renal fibrosis in 2015: understanding the mechanisms of kidney fibrosis

10.1038/nrneph.2015.215 · 2016 · External reference

Loss of Klotho contributes to kidney injury by derepression of Wnt/Beta-Catenin signaling

10.1681/asn.2012080865 · 2013 · External reference

Tubule-Derived wnts are required for fibroblast activation and kidney fibrosis

10.1681/asn.2016080902 · 2017 · External reference

Early activation of fibroblasts is required for kidney repair and regeneration after injury

10.1096/fj.201900651rr · 2019 · External reference

Natural product bruceine A from Brucea javanica (L.) merr. As a potential LDLR inhibitor that facilitates antiviral effect

10.1021/acsomega.5c02956 · 2025 · External reference