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References from 1,8-Cineole improves hepatic fibrosis by inhibiting HIF-1α/BNIP3/PINK1/Parkin-dependent mitophagy signaling and inducing apoptosis in activated hepatic stellate cells. Local targets link to admitted publications; unresolved targets remain external evidence.
Protective effect of 1, 8-cineole (eucalyptol) against lead-induced liver injury by ameliorating oxidative stress and inflammation and modulating TLR4/MyD88/NF-κB signaling
10.22038/ijbms.2024.78448.16964 · 2024 · External reference
The distinct role of HIF-1α and HIF-2α in hypoxia and angiogenesis
10.3390/cells14090673 · 2025 · External reference
Mitigating metabolic Dysfunction-associated steatotic liver disease (MASLD): the role of bioactive phytoconstituents in Indian culinary spices
10.1007/s13668-024-00598-w · 2025 · External reference
Yishen-huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway
10.3389/fmed.2025.1530092 · 2025 · External reference
Mesenchymal stem cells alleviate mouse liver fibrosis by inhibiting pathogenic function of intrahepatic B cells
10.1097/hep.0000000000000831 · 2025 · External reference
Extracellular vesicles derived from fat-laden hepatocytes undergoing chemical hypoxia promote a pro-fibrotic phenotype in hepatic stellate cells
10.1016/j.bbadis.2020.165857 · 2020 · External reference
Global epidemiology of cirrhosis - aetiology, trends and predictions
10.1038/s41575-023-00759-2 · 2023 · External reference
Overexpression of BNIP3 in renal carcinoma cells can promote apoptosis of renal carcinoma cells through HIF-1α-BNIP3-mediated autophagy
10.3389/fonc.2025.1614378 · 2025 · External reference
The circAno6/miR-296-3p/TLR4 signaling axis mediates the inflammatory response to induce the activation of hepatic stellate cells
10.1016/j.gene.2024.148497 · 2024 · External reference
Mechanism of eucalyptus oil in alleviating UUO-induced renal fibrosis revealed by transcriptomics and metabolomics
10.1016/j.phymed.2025.157133 · 2025 · External reference
Bnip3 interacts with vimentin, an intermediate filament protein, and regulates autophagy of hepatic stellate cells
10.18632/aging.202211 · 2020 · External reference
Understanding chronic inflammation: couplings between cytokines, ROS, NO, Ca(i) (2+), HIF-1α, Nrf2 and autophagy
10.3389/fimmu.2025.1558263 · 2025 · External reference
The role of PINK1-Parkin in mitochondrial quality control
10.1038/s41556-024-01513-9 · 2024 · External reference
Vanillic acid alleviates liver fibrosis through inhibiting autophagy in hepatic stellate cells via the MIF/CD74 signaling pathway
10.1016/j.biopha.2023.115673 · 2023 · External reference
Eucalyptol prevents bleomycin-induced pulmonary fibrosis and M2 macrophage polarization
10.1016/j.ejphar.2022.175184 · 2022 · External reference
Contribution of HIF-1α/BNIP3-mediated autophagy to lipid accumulation during irinotecan-induced liver injury
10.1038/s41598-023-33848-y · 2023 · External reference
TRPA1 deficiency attenuates cardiac fibrosis via regulating GRK5/NFAT signaling in diabetic rats
10.1016/j.bcp.2023.115671 · 2023 · External reference
A review of edible plant-derived natural compounds for the therapy of liver fibrosis
10.1097/meg.0000000000002483 · 2023 · External reference
The comprehensive review of eucalyptol: synthesis, metabolism, and therapeutic applications in disease treatment
10.1007/s11033-025-10461-y · 2025 · External reference
The global burden of liver disease
10.1016/j.cgh.2023.04.015 · 2023 · External reference
Liver protein and metabolite biolabels reveal hepatoprotective effects and active compounds of eucommiae folium: exploration of new application of herb based on multi-omics and bioinformatics
10.1016/j.jpba.2023.115870 · 2024 · External reference
Optimized immunofluorescence for liver structure analysis: enhancing 3D resolution and minimizing tissue autofluorescence
10.1093/biomethods/bpaf023 · 2025 · External reference
