Research graph
References from MTHFR C677T TT genotype associated with poor blood pressure control in H-type hypertension without folic acid: a retrospective cohort study. Local targets link to admitted publications; unresolved targets remain external evidence.
Pharmacogenetics of antihypertensive treatment: detailing disciplinary dissonance
10.2217/pgs.09.61 · 2009 · External reference
Riboflavin supplements for blood pressure lowering in adults
10.1002/14651858.cd015464.pub2 · 2025 · External reference
Why don't physicians follow clinical practice guidelines? A framework for improvement
10.1001/jama.282.15.1458 · 1999 · External reference
The prevalence of hypertension accompanied by high homocysteine and its risk factors in a rural population: a cross-sectional study from northeast China
10.3390/ijerph14040376 · 2017 · External reference
A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase
10.1038/ng0595-111 · 1995 · External reference
Role of homocysteine in the development of cardiovascular disease
10.1186/1475-2891-14-6 · 2015 · External reference
Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the global burden of disease study 2019
10.1016/s0140-6736(20)30752-2 · 2020 · External reference
Riboflavin lowers blood pressure in cardiovascular disease patients homozygous for the 677C T polymorphism in MTHFR
10.1097/hjh.0b013e328334c126 · 2010 · External reference
Effective control of “H-type” hypertension: a new strategy for stroke prevention
10.3760/cma.j.issn.0578-1426.2008.12.107 · 2008 · External reference
MTHFR gene and serum folate interaction on serum homocysteine lowering: prospect for precision folic acid treatment
10.1161/atvbaha.117.310211 · 2018 · External reference
Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: the CSPPT randomized clinical trial
10.1001/jama.2015.2274 · 2015 · External reference
H-type hypertension: research progress on elevated homocysteine and the occurrence and control of hypertension
10.12037/yxqy.2017.02-09 · 2017 · External reference
Pharmacogenetics and cardiovascular disease--implications for personalized medicine
10.1124/pr.112.007252 · 2013 · External reference
Effects of stress on the development and progression of cardiovascular disease
10.1038/nrcardio.2017.189 · 2018 · External reference
Expert consensus on the diagnosis and treatment of H-type hypertension
10.16439/j.cnki.1673-7245.2016.02.012 · 2016 · External reference
Effects of evidence-based clinical practice guidelines on quality of care: a systematic review
10.1136/qshc.2008.028043 · 2009 · External reference
Association between MTHFR polymorphisms and the risk of essential hypertension: an updated meta-analysis
10.3389/fgene.2021.698590 · 2021 · External reference
Strong association of methylenetetrahydrofolate reductase gene C677T polymorphism with hypertension and hypertension-in-pregnancy in Chinese: a meta-analysis
10.1038/jhh.2011.11 · 2012 · External reference
Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts
10.1016/s2468-2667(21)00302-9 · 2022 · External reference
Association of high homocysteine levels with the risk stratification in hypertensive patients at risk of stroke
10.1016/j.clinthera.2016.03.007 · 2016 · External reference
MTHFR C677T and MTR A2756G polymorphisms and the homocysteine lowering efficacy of different doses of folic acid in hypertensive Chinese adults
10.1186/1475-2891-11-2 · 2012 · External reference
Interaction of serum vitamin B(12) and folate with MTHFR genotypes on risk of ischemic stroke
10.1212/wnl.0000000000008932 · 2020 · External reference
Global burden of cardiovascular diseases and risk factors, 1990-2019: update from the GBD 2019 study
10.1016/j.jacc.2020.11.010 · 2020 · External reference
Homocysteine in microvascular endothelial cell barrier permeability
10.1385/cbb:43:1:037 · 2005 · External reference
A meta-analysis of folic acid in combination with anti-hypertension drugs in patients with hypertension and hyperhomocysteinemia
10.3389/fphar.2017.00585 · 2017 · External reference
Summary of the 2022 report on cardiovascular health and diseases in China
10.1097/cm9.0000000000002927 · 2023 · External reference
Impact of the common MTHFR 677C→T polymorphism on blood pressure in adulthood and role of riboflavin in modifying the genetic risk of hypertension: evidence from the JINGO project
10.1186/s12916-020-01780-x · 2020 · External reference
Riboflavin offers a targeted strategy for managing hypertension in patients with the MTHFR 677TT genotype: a 4-y follow-up
10.3945/ajcn.111.026245 · 2012 · External reference
Blood pressure in treated hypertensive individuals with the MTHFR 677TT genotype is responsive to intervention with riboflavin: findings of a targeted randomized trial
10.1161/hypertensionaha.111.01047 · 2013 · External reference
Unresolved reference
2012 · External reference
H-type hypertension is a risk factor for chronic total coronary artery occlusion: a cross-sectional study from southwest China
10.1186/s12872-023-03345-1 · 2023 · External reference
Methylenetetrahydrofolate reductase C677T gene polymorphism and essential hypertension: a meta-analysis of 10,415 subjects
10.3892/br.2014.302 · 2014 · External reference
Homocysteine, hypertension, and risks of cardiovascular events and all-cause death in the Chinese elderly population: a prospective study
10.11909/j.issn.1671-5411.2021.10.005 · 2021 · External reference
Prevalence, awareness, treatment, and control of hypertension in China, 2004-18: findings from six rounds of a national survey
10.1136/bmj-2022-071952 · 2023 · External reference
The interaction of hypertension and homocysteine increases the risk of mortality among middle-aged and older population in the United States
10.1097/hjh.0000000000003002 · 2022 · External reference
