References

Cysteamine attenuate intestinal reperfusion injury induced by occlusion of mesenteric artery by enhancing intracellular thiol activities

10.1055/a-1974-9132 · 2023 · External reference

Exosomes: isolation, characterization, and biomedical applications

10.1002/cbin.11620 · 2021 · External reference

Oxygen-mediated molecular mechanisms involved in intestinal ischemia and reperfusion injury

10.3390/ijms26178398 · 2025 · External reference

Mesenteric ischemia-reperfusion: an overview of preclinical drug strategies

10.1016/j.drudis.2018.05.034 · 2018 · External reference

Oxidative stress: an essential factor in the pathogenesis of gastrointestinal mucosal diseases

10.1152/physrev.00040.2012 · 2014 · External reference

Resveratrol promotes myenteric neuroprotection in the ileum of rats after ischemia-reperfusion injury

10.1016/j.lfs.2016.09.016 · 2016 · External reference

Emodin alleviates intestinal ischemia/reperfusion-induced lung injury by upregulating HO-1 expression via PI3K/Akt pathway

10.1016/j.surg.2024.04.006 · 2024 · External reference

Inflammatory biomarkers and therapeutic potential of milk exosome-mediated CCL7 siRNA in murine intestinal ischemia-reperfusion injury

10.3389/fimmu.2024.1513196 · 2025 · External reference

The rationale of targeting mammalian target of rapamycin for ischemic stroke

10.1016/j.cellsig.2013.03.017 · 2013 · External reference

Quercetin protects jejunal mucosa from experimental intestinal ischemia reperfusion injury by activation of CD68 positive cells

10.1016/j.acthis.2017.11.001 · 2018 · External reference

Vinpocetine alleviates intestinal ischemia/reperfusion injury and enhances M2 macrophage polarization in rats: role of SIRT1/SOCS3/STAT3 signaling pathway

10.1016/j.intimp.2023.110654 · 2023 · External reference

Methane saline suppresses ferroptosis via the Nrf2/HO-1 signaling pathway to ameliorate intestinal ischemia-reperfusion injury

10.1080/13510002.2024.2373657 · 2024 · External reference

Old targets, new strategy: Apigenin-7-O-β-d-(-6″-p-coumaroyl)-glucopyranoside prevents endothelial ferroptosis and alleviates intestinal ischemia-reperfusion injury through HO-1 and MAO-B inhibition

10.1016/j.freeradbiomed.2022.03.033 · 2022 · External reference

Structural mechanisms of NLRP3 inflammasome assembly and activation

10.1146/annurev-immunol-081022-021207 · 2023 · External reference

Lixisenatide reduced damage in Hippocampus CA1 neurons in a rat model of cerebral ischemia-reperfusion possibly via the ERK/P38 signaling pathway

10.1007/s12031-020-01497-9 · 2020 · External reference

Dimethyl fumarate protects against intestinal ischemia/reperfusion lesion: participation of Nrf2/HO-1, GSK-3β and Wnt/β-catenin pathway

10.1016/j.biopha.2020.111130 · 2021 · External reference

Naringin protects against inflammation and apoptosis induced by intestinal ischemia-reperfusion injury through deactivation of cGAS-STING signaling pathway

10.1002/ptr.7824 · 2023 · External reference

Novel combination of COX-2 inhibitor and antioxidant therapy for modulating oxidative stress associated with intestinal ischemic reperfusion injury and endotoxemia

10.3390/antiox9100930 · 2020 · External reference

Sirtuin 1 activator SRT1720 protects against organ injury induced by intestinal ischemia-reperfusion

10.1097/shk.0000000000000448 · 2016 · External reference

Pretreatment of cromolyn sodium prior to reperfusion attenuates early reperfusion injury after the small intestine ischemia in rats

10.3748/wjg.v13.i38.5139 · 2007 · External reference

Influence of ketotifen, cromolyn sodium, and compound 48/80 on the survival rates after intestinal ischemia reperfusion injury in rats

10.1186/1471-230x-8-42 · 2008 · External reference

NLRP3 inflammasome: a central player in renal pathologies and nephropathy

10.1016/j.lfs.2024.122813 · 2024 · External reference

N-acetylcysteine and intestinal health: a focus on its mechanism of action

10.2741/4342 · 2015 · External reference

Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway

10.1016/j.redox.2020.101534 · 2020 · External reference

N-acetylcysteine ameliorates liver injury in a rat model of intestinal ischemia reperfusion

10.1016/j.jss.2016.08.049 · 2016 · External reference

Celecoxib and rofecoxib have different effects on small intestinal ischemia/reperfusion injury in rats

10.3389/fphar.2024.1468579 · 2024 · External reference

Melatonin can be, more effective than N-acetylcysteine, protecting acute lung injury induced by intestinal ischemia-reperfusion in rat model

10.6061/clinics/2021/e2513 · 2021 · External reference

Corilagin alleviates intestinal ischemia/reperfusion-induced intestinal and lung injury in mice via inhibiting NLRP3 inflammasome activation and pyroptosis

10.3389/fphar.2022.1060104 · 2022 · External reference

Corilagin alleviates intestinal ischemia/reperfusion injury by relieving oxidative stress and apoptosis via AMPK/Sirt1-autophagy pathway

10.1177/15353702221147560 · 2023 · External reference

Ghrelin alleviates intestinal ischemia-reperfusion injury by activating the GHSR-1α/Sirt1/FOXO1 pathway

10.1096/fj.202302155rrr · 2024 · External reference

Therapeutic potential of amino acids in inflammatory bowel disease

10.3390/nu9090920 · 2017 · External reference

Quantitative proteomic analysis reveals that the Rap1/MAPK/ERK pathway is inhibited through selenomethionine strengthening antioxidant activity

10.1007/s10534-019-00229-w · 2020 · External reference

Melatonin mitigates aflatoxin B1-induced liver injury via modulation of gut microbiota/intestinal FXR/liver TLR4 signaling axis in mice

10.1111/jpi.12812 · External reference

Selenomethionine alleviates intestinal ischemia-reperfusion injury in mice through the bax-caspase pathway

10.1007/s12011-021-02925-6 · External reference

Bryostatin-1 attenuates intestinal ischemia/reperfusion-induced intestinal barrier dysfunction, inflammation, and oxidative stress via activation of Nrf2/HO-1 signaling

10.1096/fj.202201540r · 2023 · External reference

Emodin alleviates intestinal ischemia-reperfusion injury through antioxidant stress, anti-inflammatory responses and anti-apoptosis effects via Akt-mediated HO-1 upregulation

10.1186/s12950-024-00392-z · External reference

Therapeutic role of Chinese medicine targeting Nrf2/HO-1 signaling pathway in myocardial ischemia/reperfusion injury

10.1007/s11655-024-3657-0 · External reference

Extracellular vesicles derived from bone marrow mesenchymal stem cells regulate the SREBF2/HMGB1 axis by transporting miR-378a-3p to inhibit ferroptosis in intestinal ischemia-reperfusion injury

10.1038/s41420-025-02509-6 · External reference

Combined PD-1 and IL-10 blockade reinvigorates mucosal CD8+T exhaustion and ameliorates bacterial translocation and liver damage following IR

10.1016/j.bbrc.2024.151137 · External reference

Environmental microplastic accumulation exacerbates liver ischemia-reperfusion injury in rat: protective effects of melatonin

10.1016/j.scitotenv.2022.160155 · 2023 · External reference

Nrf2 and oxidative stress: a general overview of mechanisms and implications in human disease

10.3390/antiox11122345 · 2022 · External reference

Protective effects of N-acetyl-L-cysteine and platelet activating factor inhibition are not linked to intercellular adhesion molecule-1 expression after intestinal ischemia and reperfusion injury in rats

10.1080/00365520310002201 · 2003 · External reference

Melatonin exhibits supportive effects on oxidants and anastomotic healing during intestinal ischemia/reperfusion injury

10.5505/tjtes.2017.23539 · 2018 · External reference

Honokiol protects the kidney from renal ischemia and reperfusion injury by upregulating the glutathione biosynthetic enzymes

10.3390/biomedicines8090352 · 2020 · External reference

The Eph/ephrin system symphony of gut inflammation

10.1016/j.phrs.2023.106976 · 2023 · External reference

Amelioration of intestinal ischemia reperfusion injury by carvedilol via regulation of eNOS/VEGF-A and inflammasome/IL1β/TNFα pathways

10.1016/j.ejphar.2025.178097 · 2025 · External reference

Antioxidant effect of a Fucus vesiculosus extract on intestinal ischemia/reperfusion injury in rats: a biochemical and histological study

10.3390/antiox14060624 · 2025 · External reference

Esculetin alleviates inflammation, oxidative stress and apoptosis in intestinal ischemia/reperfusion injury via targeting SIRT3/AMPK/mTOR signaling and regulating autophagy

10.2147/jir.s413941 · 2023 · External reference

Bone marrow mesenchymal stem cell-derived exosomes accelerate functional recovery after spinal cord injury by promoting the phagocytosis of macrophages to clean Myelin debris

10.3389/fcell.2021.772205 · 2021 · External reference

Macrophage membrane coated manganese dioxide nanoparticles loaded with rapamycin alleviate intestinal ischemia-reperfusion injury by reducing oxidative stress and enhancing autophagy

10.2147/ijn.s507546 · 2025 · External reference

Plant-derived secondary metabolites and nanotechnology: innovative strategies and emerging challenges in myocardial ischemia-reperfusion injury therapy

10.3389/fphar.2025.1529478 · 2025 · External reference

Protective effects of thymoquinone and melatonin on intestinal ischemia-reperfusion injury

10.4103/1319-3767.166203 · 2015 · External reference

Association of nanoparticles and Nrf2 with various oxidative stress-mediated diseases

10.1016/j.cbi.2023.110535 · 2023 · External reference

Quercetin attenuates the ischemia reperfusion induced COX-2 and MPO expression in the small intestine mucosa

10.1016/j.biopha.2017.08.038 · 2017 · External reference

The effects of S-nitrosoglutathione on intestinal ischemia reperfusion injury and acute lung injury in rats: roles of oxidative stress and NF-κB

10.1016/j.tice.2018.03.012 · 2018 · External reference

Modulation of the oxidative stress and ICAM-1/TLR4/NF-Κβ levels by metformin in intestinal ischemia/Reperfusion injury in rats

10.1007/s12013-025-01687-5 · 2025 · External reference

N-acetylcysteine expresses powerful anti-inflammatory and antioxidant activities resulting in complete improvement of acetic acid-induced colitis in rats

10.3109/00365513.2012.734859 · 2013 · External reference

Inhibition of complement C5 reduces local and remote organ injury after intestinal ischemia/reperfusion in the rat

10.1053/gast.2001.20873 · 2001 · External reference

Selenomethionine improves antioxidant capacity of breast muscle in geese via stimulating the glutathione system and thiol pool

10.1007/s12011-020-02052-8 · 2020 · External reference

Precision therapeutics for inflammatory bowel disease: advancing ROS-responsive nanoparticles for targeted and multifunctional drug delivery

10.1039/d4tb02868f · 2025 · External reference

SIRT3-mediated deacetylation of PRDX3 alleviates mitochondrial oxidative damage and apoptosis induced by intestinal ischemia/reperfusion injury

10.1016/j.redox.2019.101343 · 2020 · External reference

Human breast milk-derived exosomes protect against intestinal ischemia and reperfusion injury in neonatal rats

10.1016/j.jpedsurg.2022.02.029 · 2022 · External reference

Corilagin attenuates intestinal ischemia/reperfusion injury in mice by inhibiting ferritinophagy-mediated ferroptosis through disrupting NCOA4-ferritin interaction

10.1016/j.lfs.2023.122176 · External reference

Ginsenoside Rg3 enriches SCFA-producing commensal bacteria to confer protection against enteric viral infection via the cGAS-STING-type I IFN axis

10.1038/s41396-023-01541-7 · External reference

Corilagin alleviated intestinal ischemia-reperfusion injury by modulating endoplasmic reticulum stress via bonding with Bip

10.1016/j.phymed.2024.156011 · 2024 · External reference

Gut microbiota-derived glutathione from metformin treatment alleviates intestinal ferroptosis induced by ischemia/reperfusion

10.1186/s12916-025-04119-6 · 2025 · External reference

Effects of verapamil on intestinal injury in a rat model of acute mesenteric ischemia

10.1016/j.sipas.2025.100286 · 2025 · External reference

Dexmedetomidine alleviates intestinal ischemia/reperfusion injury by modulating intestinal neuron autophagy and mitochondrial homeostasis via Nupr1 regulation

10.1186/s10020-024-00952-2 · 2024 · External reference

Honokiol ameliorates pyroptosis in intestinal ischemia-reperfusion injury by regulating the SIRT3-mediated NLRP3 inflammasome

10.3892/ijmm.2025.5537 · 2025 · External reference

Porcine milk exosome MiRNAs attenuate LPS-induced apoptosis through inhibiting TLR4/NF-κB and p53 pathways in intestinal epithelial cells

10.1021/acs.jafc.9b02925 · 2019 · External reference

Regulation of N-acetyl cysteine on gut redox status and major microbiota in weaned piglets

10.2527/jas.2013-6755 · 2014 · External reference

Rapamycin promotes the intestinal barrier repair in ulcerative colitis via the mTOR/PBLD/AMOT signaling pathway

10.1016/j.bbadis.2024.167287 · External reference

Intestinal targeted nanogel with broad-spectrum autonomous ROS scavenging performance for enhancing the bioactivity of trans-resveratrol

10.2147/ijn.s464849 · External reference

Mechanism of resveratrol alleviating intestinal ischemia reperfusion injury by inhibiting ferroptosis

2025 · External reference

Melatonin alleviates intestinal injury, neuroinflammation and cognitive dysfunction caused by intestinal ischemia/reperfusion

10.1016/j.intimp.2020.106596 · External reference

Amelioration of coagulation disorders and inflammation by hydrogen-rich solution reduces intestinal ischemia/reperfusion injury in rats through NF-κB/NLRP3 pathway

10.1155/2020/4359305 · External reference

Dexmedetomidine resists intestinal ischemia-reperfusion injury by inhibiting TLR4/MyD88/NF-κB signaling

10.1016/j.jss.2020.11.041 · 2021 · External reference

Resveratrol primed adipose stem cell-derived exosomes alleviate intestinal ischemia reperfusion injury by regulating macrophage polarization

10.1016/j.intimp.2025.115481 · 2025 · External reference

Melatonin modulates TLR4/MyD88/NF-κB signaling pathway to ameliorate cognitive impairment in sleep-deprived rats

10.3389/fphar.2024.1430599 · 2024 · External reference

Mesna protects intestinal mucosa from ischemia/reperfusion injury

10.1016/j.jss.2005.12.031 · 2006 · External reference

Baicalin alleviates intestinal ischemia-reperfusion injury by regulating ferroptosis mediated by nuclear factor E2-related factor 2/glutathione peroxidase 4 signaling pathway

10.26402/jpp.2024.5.07 · 2024 · External reference

mtDNA-STING pathway promotes necroptosis-dependent enterocyte injury in intestinal ischemia reperfusion

10.1038/s41419-020-03239-6 · 2020 · External reference

Exosomes derived from BMSCs ameliorate intestinal ischemia-reperfusion injury by regulating miR-144-3p-Mediated oxidative stress

10.1007/s10620-022-07546-0 · 2022 · External reference

Exosomal circEZH2_005, an intestinal injury biomarker, alleviates intestinal ischemia/reperfusion injury by mediating Gprc5a signaling

10.1038/s41467-023-41147-3 · 2023 · External reference

The role of the effects of autophagy on NLRP3 inflammasome in inflammatory nervous system diseases

10.3389/fcell.2021.657478 · 2021 · External reference

Apigenin-7-glucoside-loaded nanoparticle alleviates intestinal ischemia-reperfusion by ATF3/SLC7A11-mediated ferroptosis

10.1016/j.jconrel.2023.12.038 · 2024 · External reference

Orchestrating cellular fate: post-translational modifications as master regulators and therapeutic targets in intestinal ischemia-reperfusion injury

10.1016/j.bbrc.2025.152549 · 2025 · External reference

Oral lipid nanoparticles for improving the efficiency of drug delivery systems in ulcerative colitis: recent advances and future prospects

10.3390/pharmaceutics17050547 · 2025 · External reference

Liraglutide attenuates intestinal ischemia/reperfusion injury via NF-κB and PI3K/Akt pathways in mice

10.1016/j.lfs.2022.121045 · 2022 · External reference