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References from Research progress on targeting autophagy pathways with medicinal plants and their active metabolites for the treatment of heart failure. Local targets link to admitted publications; unresolved targets remain external evidence.
Berberine promotes cardiac function by upregulating PINK1/Parkin-mediated mitophagy in heart failure
10.3389/fphys.2020.565751 · 2020 · External reference
Red ginseng extract improves coronary flow reserve and increases absolute numbers of various circulating angiogenic cells in patients with first ST-segment elevation acute myocardial infarction
10.1002/ptr.3250 · 2011 · External reference
Berberine: a review of its pharmacokinetics properties and therapeutic potentials in diverse vascular diseases
10.3389/fphar.2021.762654 · 2021 · External reference
Quercetin derivatives: drug design, development, and biological activities, a review
10.1016/j.ejmech.2021.114068 · 2022 · External reference
The role of biomarkers in valvular heart disease: focus on natriuretic peptides
10.1016/j.cjca.2014.07.014 · 2014 · External reference
Heart failure in the elderly: epidemiology, mechanisms, and management
10.1093/eurheartj/ehag110 · 2026 · External reference
Effects of resveratrol (trans-3,5,4′-trihydroxystilbene) treatment on cardiac remodeling following myocardial infarction
10.1124/jpet.107.127548 · 2007 · External reference
Resveratrol mediates mitochondrial function through the sirtuin 3 pathway to improve abnormal metabolic remodeling in atrial fibrillation
10.4081/ejh.2024.4004 · 2024 · External reference
Berberine reduces atrial lipotoxicity and endoplasmic reticulum stress to alleviate heart failure with preserved ejection fraction (HFpEF)-associated atrial fibrillation via AMPK signaling
10.1002/ptr.70193 · 2026 · External reference
YY1 nitration participates in DbCM cardiomyocyte lipotoxicity by inhibiting ANXA3-induced microlipophagy
10.1016/j.redox.2026.104085 · 2026 · External reference
XS0601 reduces the incidence of restenosis: a prospective study of 335 patients undergoing percutaneous coronary intervention in China
10.1097/00029330-200601010-00002 · 2006 · External reference
Paeoniflorin improves cardiac function and decreases adverse postinfarction left ventricular remodeling in a rat model of acute myocardial infarction
10.2147/dddt.s163405 · 2018 · External reference
Paeoniflorin prevents endoplasmic reticulum stress-associated inflammation in lipopolysaccharide-stimulated human umbilical vein endothelial cells via the IRE1α/NF-κB signaling pathway
10.1039/c7fo01406f · 2018 · External reference
Cardio-protective effect of tetrahydrocurcumin, the primary hydrogenated metabolite of curcumin in vivo and in vitro: induction of apoptosis and autophagy via PI3K/AKT/mTOR pathways
10.1016/j.ejphar.2021.174495 · 2021 · External reference
Protection of H9c2 myocardial cells from oxidative stress by crocetin via PINK1/Parkin pathway-mediated mitophagy
10.3791/65105 · 2023 · External reference
How autophagy, a potential therapeutic target, regulates intestinal inflammation
10.3389/fimmu.2023.1087677 · 2023 · External reference
Carthamus tinctorius L. protects cerebral ischemia/reperfusion injury via arachidonic acid/p53-mediated apoptosis axis
10.3389/fphar.2024.1504109 · 2024 · External reference
Resveratrol protects against doxorubicin-induced cardiotoxicity by attenuating ferroptosis through modulating the MAPK signaling pathway
10.1016/j.taap.2023.116794 · 2024 · External reference
Songorine ameliorates LPS-induced sepsis cardiomyopathy by Wnt/β-catenin signaling pathway-mediated mitochondrial biosynthesis
10.1007/s00210-023-02897-5 · 2024 · External reference
Mechanism of Astragalus membranaceus (Huangqi, HQ) for treatment of heart failure based on network pharmacology and molecular docking
10.1111/jcmm.18331 · 2024 · External reference
Huangqi-Danshen decoction improves heart failure by regulating pericardial adipose tissue derived extracellular vesicular miR-27a-3p to activate AMPKα2 mediated mitophagy
10.1016/j.phymed.2024.156187 · 2024 · External reference
PRKN-IMMT/MIC60 axis promotes myocardial ischemia-reperfusion injury via lysosomal degradation of GPX4
10.1080/15548627.2026.2674713 · 2026 · External reference
Baicalin alleviates angiotensin II-induced cardiomyocyte apoptosis and autophagy and modulates the AMPK/mTOR pathway
10.1111/jcmm.18321 · 2024 · External reference
Ershen Zhenwu decoction suppresses myocardial fibrosis of chronic heart failure with heart-kidney Yang deficiency by down-regulating the Ras Homolog Gene Family Member A/Rho-Associated Coiled-Coil Kinases signaling pathway
10.1016/j.jep.2024.119146 · 2025 · External reference
Autolysosomal dysfunction in obesity-induced metabolic inflammation and related disorders
10.1007/s13679-025-00638-8 · 2025 · External reference
Autophagy-inflammasome interplay in heart failure: a systematic review on basics, pathways, and therapeutic perspectives
2017 · External reference
β-hydroxybutyrate administered at reperfusion reduces infarct size and preserves cardiac function by improving mitochondrial function through autophagy in male mice
10.1016/j.yjmcc.2023.11.001 · 2024 · External reference
Autophagy, ER-phagy and ER dynamics during cell differentiation
10.1016/j.jmb.2025.169151 · 2025 · External reference
Autophagy and oncosis/necroptosis are enhanced in cardiomyocytes from heart failure patients
10.12659/msmbr.913436 · 2019 · External reference
Si-Miao-Yong-An decoction maintains the cardiac function and protects cardiomyocytes from myocardial ischemia and reperfusion injury
10.1155/2021/8968464 · 2021 · External reference
Berberine impairs coxsackievirus B3-induced myocarditis through the inhibition of virus replication and host pro-inflammatory response
10.1002/jmv.26747 · 2021 · External reference
Anti-heart failure mechanism of saponin extract of black ginseng based on metabolomics
10.1016/j.jpba.2023.115738 · 2023 · External reference
Mechanistic insights into Shengxian Sanren granules’ effects on chronic heart failure: a synergistic study of UPLC-Q-TOF-MS/MS and network pharmacology
10.1016/j.fitote.2025.106859 · 2025 · External reference
Natural history of MYH7-related dilated cardiomyopathy
10.1016/j.jacc.2022.07.023 · 2022 · External reference
Influence of cinnamaldehyde on viral myocarditis in mice
10.1097/maj.0b013e3181dd3b43 · 2010 · External reference
Multiple mitochondria-targeted components screened from Sini decoction improved cardiac energetics and mitochondrial dysfunction to attenuate doxorubicin-induced cardiomyopathy
10.7150/thno.80066 · 2023 · External reference
SIRT1 is a regulator of autophagy: implications for the progression and treatment of myocardial ischemia-reperfusion
10.1016/j.phrs.2023.106957 · 2024 · External reference
Determination of songorine in rat plasma by UPLC-MS/MS: assay development and application to pharmacokinetic study
10.1016/j.jchromb.2015.08.037 · 2015 · External reference
Astragaloside IV ameliorates diabetic cardiomyopathy by suppressing the GNG2/MRAS-ERK signaling pathway
10.2147/ijgm.s544287 · 2026 · External reference
Black ginseng: a novel medicine for treating heart failure
10.3389/fphar.2024.1429214 · 2024 · External reference
Autophagy and heart failure
10.1007/978-981-15-4272-5_16 · 2020 · External reference
Plantamajoside alleviates hypoxia-reoxygenation injury through integrin-linked kinase/c-Src/Akt and the mitochondrial apoptosis signaling pathways in H9c2 myocardial cells
10.1186/s12906-023-03880-6 · 2023 · External reference
Gypenosides alleviates MCT-induced pulmonary arterial hypertension in rats by targeting oxidative stress, inflammation, and apoptosis
10.22038/ijbms.2025.82437.17822 · 2025 · External reference
Qili Qiangxin, a compound herbal medicine formula, alleviates hypoxia-reoxygenation-induced apoptotic and autophagic cell death via suppression of ROS/AMPK/mTOR pathway in vitro
10.1016/j.joim.2022.04.005 · 2022 · External reference
The synergistic mechanism of total saponins and flavonoids in notoginseng-safflower against myocardial infarction using a comprehensive metabolomics strategy
10.3390/molecules27248860 · 2022 · External reference
Effect of resveratrol on blood pressure: a systematic review and meta-analysis of randomized, controlled, clinical trials
10.1080/10408398.2017.1422480 · 2019 · External reference
An update on heart failure: new definitions and treatment
10.1016/j.pop.2023.08.004 · 2024 · External reference
Peri-mitochondrial actin filaments inhibit parkin assembly by disrupting ER-mitochondria contacts
10.1038/s44319-025-00561-y · 2025 · External reference
Sophoricoside ameliorates cardiac hypertrophy by activating AMPK/mTORC1-mediated autophagy
10.1042/bsr20200661 · 2020 · External reference
Clinical study of Ershen Zhenwu decoction on miR-423-5p/smad7/TGF-β/smad
10.13422/j.cnki.syfjx.20252094 · 2025 · External reference
The interplay involving oxidative stress and autophagy: mechanisms, implications, and therapeutic opportunities
10.1016/j.yexmp.2025.104989 · 2025 · External reference
Structure, property, biogenesis, and activity of diterpenoid alkaloids containing a sulfonic acid group from Aconitum carmichaelii
10.1016/j.apsb.2020.01.013 · 2020 · External reference
Molecular mechanisms and intervention approaches of heart failure (Review)
10.3892/ijmm.2025.5566 · 2025 · External reference
Regulation of the NLRP3 inflammasome by autophagy and mitophagy
10.1111/imr.13410 · 2025 · External reference
Therapeutic implications of targeting pyroptosis in cardiac-related etiology of heart failure
10.1016/j.bcp.2022.115235 · 2022 · External reference
Plantamajoside promotes NGF/TrkA pathway to inhibit neuronal apoptosis and improve diabetic peripheral neuropathy
10.1111/jcmm.70571 · 2025 · External reference
NLR/inflammasome pathway in cardiovascular disorders: from pathogenesis to potential therapies
10.1080/00015385.2025.2515322 · 2025 · External reference
Potential mechanisms of Qili Qiangxin capsule to prevent pulmonary arterial hypertension based on network pharmacology analysis in a rat model
10.21037/atm-22-901 · 2022 · External reference
Effect of berberine on global modulation of lncRNAs and mRNAs expression profiles in patients with stable coronary heart disease
10.1186/s12864-022-08641-2 · 2022 · External reference
Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis
10.3389/fphar.2024.1345797 · 2024 · External reference
Role of AMP-activated protein kinase in the metabolic syndrome and in heart disease
10.1016/j.febslet.2007.11.018 · 2008 · External reference
Songorine modulates macrophage polarization and metabolic reprogramming to alleviate inflammation in osteoarthritis
10.3389/fimmu.2024.1344949 · 2024 · External reference
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
10.1038/nrm3270 · 2012 · External reference
Mitochondrial structure and function in human heart failure
10.1161/circresaha.124.323800 · 2024 · External reference
Pharmacokinetic properties of saffron and its active components
10.1007/s13318-017-0449-3 · 2018 · External reference
Salvianolic acid B alleviates myocardial ischemic injury by promoting mitophagy and inhibiting activation of the NLRP3 inflammasome
10.3892/mmr.2020.11589 · 2020 · External reference
Omentin1 ameliorates myocardial ischemia-induced heart failure via SIRT3/FOXO3a-dependent mitochondrial dynamical homeostasis and mitophagy
10.1186/s12967-022-03642-x · 2022 · External reference
Finding new targets for the treatment of heart failure: endoplasmic reticulum stress and autophagy
10.1007/s12265-023-10410-9 · 2023 · External reference
Resveratrol improved atherosclerosis by increasing LDLR levels via the EGFR-ERK1/2 signaling pathway
10.1186/s12944-025-02585-8 · 2025 · External reference
Cinnamaldehyde attenuates diabetic cardiomyopathy by ameliorating energy metabolism disturbance and activating autophagy
10.1097/fjc.0000000000001694 · 2025 · External reference
Multi-component synergy of safflower (Carthamus tinctorius L.) against hypertension-dyslipidemia: network pharmacology and molecular docking study
10.1016/j.compbiolchem.2025.108831 · 2026 · External reference
Recent trends in ginseng research
10.1007/s11418-024-01792-4 · 2024 · External reference
Upregulation of autophagy genes and the unfolded protein response in human heart failure
2017 · External reference
Safflower extract inhibiting apoptosis by inducing autophagy in myocardium derived H9C2 cell
2015 · External reference
Plantamajoside alleviates DSS-induced ulcerative colitis by modulating gut microbiota, upregulating CBS, and inhibiting NF-κB
10.1016/j.phymed.2025.156827 · 2025 · External reference
A pharmacokinetics-pharmacodynamics study of single-dose total glucosides of paeony capsule on reducing serum total bile acid in hepatic injury rats
10.1080/13880209.2021.1937232 · 2021 · External reference
Elucidating the mechanism of action of astragalus polysaccharide on ionizing radiation-induced myocardial damage based on network pharmacology and experimental research
10.1016/j.intimp.2024.113758 · 2025 · External reference
Histidine triad nucleotide-binding protein 2 attenuates doxorubicin-induced cardiotoxicity through restoring lysosomal function and promoting autophagy in mice
10.1002/mco2.70075 · 2025 · External reference
Astragaloside IV inhibits the progression of hypertensive heart disease via the RXRA/PPARG/SIRT3 axis
10.1007/s00109-025-02607-z · 2025 · External reference
Resveratrol supplementation: a therapeutic potential for cardiac remodeling in hypertensive heart disease
10.1038/s41440-023-01277-z · 2023 · External reference
Traditional herbal medicine Oryeongsan for heart failure: a systematic review and meta-analysis
10.1016/j.heliyon.2024.e37830 · 2024 · External reference
Screening for antibacterial and antibiofilm activities in astragalus angulosus
10.5455/jice.20161018101720 · 2017 · External reference
Resveratrol reverses remodeling in hearts with large, old myocardial infarctions through enhanced autophagy-activating AMP kinase pathway
10.1016/j.ajpath.2012.11.009 · 2013 · External reference
Colchicine in coronary artery disease
10.1136/postgradmedj-2020-139611 · 2022 · External reference
Targeting Rab7-Rilp mediated microlipophagy alleviates lipid toxicity in diabetic cardiomyopathy
10.1002/advs.202401676 · 2024 · External reference
The role of quercetin and exercise in modulating apoptosis and cardiomyopathy via PI3K/AKT/FOXO3 pathways in diabetic obese rats
10.22074/cellj.2024.2042044.1682 · 2025 · External reference
Therapeutic potential of songorine, a diterpenoid alkaloid of the genus Aconitum
10.1016/j.ejmech.2017.10.065 · 2018 · External reference
Sophoricoside from Styphnolobium japonicum improves experimental atopic dermatitis in mice
10.1016/j.phymed.2021.153463 · 2021 · External reference
Role of macroautophagy in mammalian male reproductive physiology
10.3390/cells12091322 · 2023 · External reference
Gut-heart axis: cardiac remodeling and heart failure in the context of inflammatory bowel disease and dysbiosis
10.1152/ajpgi.00016.2025 · 2025 · External reference
Safflower yellow injection combined with conventional therapy in treating unstable angina pectoris: a meta-analysis
10.1016/s0254-6272(14)60021-2 · 2013 · External reference
Linggui Zhugan decoction ameliorating mitochondrial damage of doxorubicin-induced cardiotoxicity by modulating the AMPK-FOXO3a pathway targeting BTG2
10.1016/j.phymed.2025.156529 · 2025 · External reference
Oxidative stress, mitochondrial quality control, autophagy, and sirtuins in heart failure
10.3390/ijms26199826 · 2025 · External reference
The effects of resveratrol and SIRT1 activation on dystrophic cardiomyopathy
10.1111/nyas.12812 · 2015 · External reference
BNIP3L/NIX and FUNDC1-mediated mitophagy is required for mitochondrial network remodeling during cardiac progenitor cell differentiation
10.1080/15548627.2019.1580095 · 2019 · External reference
Heart failure: innovative understanding from traditional Chinese medicine (TCM) and treatment with classic TCM formulas
10.19540/j.cnki.cjcmm.20240814.501 · 2024 · External reference
Lipotoxicity: a driver of heart failure with preserved ejection fraction?
10.1042/cs20210127 · 2021 · External reference
AMPK and autophagy
10.1007/978-981-15-0602-4_4 · 2019 · External reference
A multicenter, randomized, double-blind, parallel-group, placebo-controlled study of the effects of qili qiangxin capsules in patients with chronic heart failure
10.1016/j.jacc.2013.05.035 · 2013 · External reference
Distinct changes of myocyte autophagy during myocardial hypertrophy and heart failure: association with oxidative stress
10.1113/ep085586 · 2016 · External reference
Paeoniflorin inhibits doxorubicin-induced cardiomyocyte apoptosis by downregulating microRNA-1 expression
10.3892/etm.2016.3182 · 2016 · External reference
AMPK blunts chronic heart failure by inhibiting autophagy
10.1042/bsr20170982 · 2018 · External reference
Cinnamaldehyde attenuates atherosclerosis via targeting the IκB/NF-κB signaling pathway in high fat diet-induced ApoE-/- mice
10.1039/c9fo00396g · 2019 · External reference
AMPK: a therapeutic target of heart failure-not only metabolism regulation
10.1042/bsr20181767 · 2019 · External reference
A systems pharmacology approach for identifying the multiple mechanisms of action for the Rougui-Fuzi herb pair in the treatment of cardiocerebral vascular diseases
10.1155/2020/5196302 · 2020 · External reference
Songorine promotes cardiac mitochondrial biogenesis via Nrf2 induction during sepsis
10.1016/j.redox.2020.101771 · 2021 · External reference
Idebenone attenuates ferroptosis by inhibiting excessive autophagy via the ROS-AMPK-mTOR pathway to preserve cardiac function after myocardial infarction
10.1016/j.ejphar.2023.175569 · 2023 · External reference
Chemical differentiation and quantitative analysis of black ginseng based on an LC-MS combined with multivariate statistical analysis approach
10.3390/molecules28135251 · 2023 · External reference
Paeoniflorin mitigates MMP-12 inflammation in silicosis via yang-yin-qing-fei Decoction in murine models
10.1016/j.phymed.2024.155616 · 2024 · External reference
Targeted treatment of myocardial infarction by macrophage membrane coated with resveratrol nanoparticles
10.1021/acsomega.4c07573 · 2024 · External reference
Exploring the mechanism of action of berberine on arrhythmia after myocardial infarction: a network pharmacology, molecular docking, and cellular experimental study
10.1155/cdr/5632985 · 2025 · External reference
Chlorogenic acid and ferulic acid in SMYAD alleviate diabetic cardiomyopathy by inhibiting cardiac lipotoxicity via GCGR/PPARα and GCGR/AMPK pathways
10.1016/j.phymed.2025.156906 · 2025 · External reference
Astragaloside IV alleviates radiation-induced heart disease by regulating energy metabolism
10.1016/j.phymed.2025.157135 · 2025 · External reference
Astragalus membranaceus injection activates mitophagy and protects mitochondrial function in chronic heart failure via inhibiting AKT/mTOR pathway
10.1038/s41598-025-27065-y · 2025 · External reference
The UCP2/PINK1/LC3b-mediated mitophagy is involved in the protection of NRG1 against myocardial ischemia/reperfusion injury
10.1016/j.redox.2025.103511 · 2025 · External reference
Qualitative and quantitative analysis of lipo-alkaloids and fatty acids in aconitum carmichaelii using LC-MS and GC-MS
10.1002/pca.2760 · 2018 · External reference
Pharmacological effects of astragaloside IV: a review
10.3390/molecules28166118 · 2023 · External reference
Main active components of Si-Miao-Yong-An decoction (SMYAD) attenuate autophagy and apoptosis via the PDE5A-AKT and TLR4-NOX4 pathways in isoproterenol (ISO)-induced heart failure models
10.1016/j.phrs.2022.106077 · 2022 · External reference
AMPK: sensing glucose as well as cellular energy status
10.1016/j.cmet.2017.10.009 · 2018 · External reference
PLINs-mediated organelle interactions: a key of exercise-mediated improvement of skeletal muscle lipid metabolism disorders
10.3389/fendo.2025.1700668 · 2025 · External reference
Determination of twelve active compounds in Qili Qiangxin capsules by UPLC-MS
2014 · External reference
Paeoniflorin improves pressure overload-induced cardiac remodeling by modulating the MAPK signaling pathway in spontaneously hypertensive rats
10.1016/j.biopha.2018.12.090 · 2019 · External reference
Chemical constituents of Panax ginseng and Panax notoginseng explain why they differ in therapeutic efficacy
10.1016/j.phrs.2020.105263 · 2020 · External reference
Paeoniflorin attenuates myocardial fibrosis in isoprenaline-induced chronic heart failure rats via inhibiting P38 MAPK pathway
10.1007/s11596-020-2178-0 · 2020 · External reference
Therapeutic potential of traditional Chinese medicine in atherosclerosis: a review
10.1002/ptr.7590 · 2022 · External reference
Astragalus injection ameliorates lipopolysaccharide-induced cognitive decline via relieving acute neuroinflammation and BBB damage and upregulating the BDNF-CREB pathway in mice
10.1080/13880209.2022.2062005 · 2022 · External reference
Effectiveness and safety of Linggui Zhugan decoction for the treatment of premature contraction in patients with coronary heart disease: a systematic review and meta-analysis
10.3389/fcvm.2022.1002378 · 2022 · External reference
AMPK signalling pathway: a potential strategy for the treatment of heart failure with Chinese medicine
10.2147/jir.s441597 · 2023 · External reference
Autophagy: regulator of cell death
10.1038/s41419-023-06154-8 · 2023 · External reference
Emerging role of mitophagy in heart failure: from molecular mechanism to targeted therapy
10.1080/15384101.2023.2167949 · 2023 · External reference
Mitochondrial quality control in human health and disease
10.1186/s40779-024-00536-5 · 2024 · External reference
Resveratrol alleviates heart failure by activating foxo3a to counteract oxidative stress and apoptosis
10.1016/j.biopha.2024.117716 · 2024 · External reference
A versatile economic strategy by HPLC-CAD for quantification of structurally diverse markers in quality control of Shengmai Formula from raw materials to preparations
10.1016/j.phymed.2024.155625 · 2024 · External reference
Astragalus injection inhibits the growth of osteosarcoma by activating cytotoxic T lymphocyte and targeting CTSL
10.1016/j.jep.2025.119607 · 2025 · External reference
SIRT3 attenuates sepsis-induced EndMT and cardiac remodeling by facilitating mitophagy process via PINK1/Parkin signaling
10.1016/j.intimp.2025.115377 · 2025 · External reference
Mechanism of Ershen Zhenwu decoction in ameliorating chronic heart failure via JNK/MAPK-regulated apoptosis: insights from network pharmacology and experimental validation
10.3389/fcvm.2025.1561963 · 2025 · External reference
Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway
10.1111/bph.70257 · 2026 · External reference
Self-assembly of glycyrrhizic acid and aconitine alleviates heart failure by inhibiting autophagy and inducing reprogramming of energy metabolism
10.1016/j.phymed.2026.158094 · 2026 · External reference
Elucidating the mechanism of action of the astragalus-ginseng herb pair in treating coronary heart disease: a network pharmacology and experimental validation approach
10.1177/15491684261446288 · 2026 · External reference
Quercetin improves heart failure by inhibiting cardiomyocyte apoptosis via suppressing the MAPK signaling pathway
10.12122/j.issn.1673-4254.2025 · 2025 · External reference
Regulated cell death and inflammatory signaling in diabetic cardiomyopathy: mechanisms and therapeutic strategies
10.1007/s12265-025-10701-3 · 2025 · External reference
Colchicine-phoenix from the ashes
10.1007/s00508-024-02490-7 · 2025 · External reference
Effects of Astragalus injection and Salvia Miltiorrhiza injection on serum inflammatory markers in patients with stable coronary heart disease: a randomized controlled trial protocol
10.1186/s13063-020-4109-6 · 2020 · External reference
Meta-analysis for the value of colchicine for the therapy of pericarditis and of postpericardiotomy syndrome
10.1186/s12872-019-1190-4 · 2019 · External reference
Quercetin alleviates postmenopausal atherosclerosis by suppressing endothelial cell ferroptosis via regulating the KEAP1/NRF2/GPX4 signalling pathway
10.1111/bph.70200 · 2026 · External reference
Extracts from Astragalus membranaceus limit myocardial cell death and improve cardiac function in a rat model of myocardial ischemia
10.1016/j.jep.2013.07.036 · 2013 · External reference
Fuyu decoction improves ventricular remodeling in rats with heart failure by inhibiting AMPK/mTOR pathway-mediated autophagy
10.12122/j.issn.1673-4254.2023.03.18 · 2023 · External reference
Influence and molecular mechanism of cinnamaldehyde against ventricular arrhythmia via the TAK1-p38MAPK-NLRP3 pathway
10.1007/s00380-025-02529-3 · 2025 · External reference
Quercetin reverses β1-adrenoceptor autoantibody-induced heart failure by promoting MDM2-mediated ubiquitination and degradation of p53 in cardiomyocytes
10.3389/fnut.2025.1674507 · 2025 · External reference
VPS35 mutation inhibits PINK1/parkin-mediated mitophagy via increased LRRK2 kinase activity
10.1093/brain/awaf414 · 2025 · External reference
Cinnamaldehyde alleviates doxorubicin-induced cardiotoxicity by decreasing oxidative stress and ferroptosis in cardiomyocytes
10.1371/journal.pone.0292124 · 2023 · External reference
Saffron (Crocus sativus L.) and its by-products: healthy effects in internal medicine
10.3390/nu16142319 · 2024 · External reference
A network pharmacology study to explore the underlying mechanism of safflower (Carthamus tinctorius L.) in the treatment of coronary heart disease
10.1155/2022/3242015 · 2022 · External reference
The anti-senescence effect of D-β-hydroxybutyrate in Hutchinson-Gilford progeria syndrome involves progerin clearance by the activation of the AMPK-mTOR-autophagy pathway
10.1007/s11357-024-01501-9 · 2025 · External reference
Quercetin reduces vascular senescence and inflammation in symptomatic male but not female coronary artery disease patients
10.1111/acel.70108 · 2025 · External reference
Intestinal fatty acid binding protein is associated with cardiac function and gut dysbiosis in chronic heart failure
10.3389/fcvm.2023.1160030 · 2023 · External reference
Historical landmarks of autophagy research
10.1038/cr.2013.169 · 2014 · External reference
Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure
10.1038/nature10992 · 2012 · External reference
Molecular mechanisms and physiological functions of mitophagy
10.15252/embj.2020104705 · 2021 · External reference
The red wine hypothesis: from concepts to protective signalling molecules
10.1093/eurheartj/ehm149 · 2007 · External reference
Mapping the interplay of immunoproteasome and autophagy in different heart failure phenotypes
10.1016/j.freeradbiomed.2024.03.026 · 2024 · External reference
Targeting key inflammatory mechanisms underlying heart failure: a comprehensive review
10.3390/ijms25010510 · 2023 · External reference
Identification of pan-assay interference compoundS (PAINS) using an MD-based protocol
10.1007/978-1-0716-1468-6_15 · 2021 · External reference
Low-dose colchicine ameliorates doxorubicin cardiotoxicity via promoting autolysosome degradation
10.1161/jaha.123.033700 · 2024 · External reference
Regulation of autophagy of the heart in ischemia and reperfusion
10.1007/s10495-022-01786-1 · 2023 · External reference
AMPK: energy sensor and survival mechanism in the ischemic heart
10.1016/j.tem.2015.05.010 · 2015 · External reference
Astragalus polysaccharide improves myocardial fibrosis in hypertrophic cardiomyopathy through the TGF-β1/Smad3 signal pathway
10.31083/fbl45595 · 2025 · External reference
The role of myocardial mitochondrial quality control in heart failure
10.3389/fphar.2019.01404 · 2019 · External reference
Action and therapeutic targets of folliculin interacting protein 1: a novel signaling mechanism in redox regulation
10.3389/fcell.2025.1523489 · 2025 · External reference
Mitochondrial quality control in cardiomyocytes: safeguarding the heart against disease and ageing
10.1038/s41569-025-01142-1 · 2025 · External reference
Bioinformatics and animal experiments reveal mechanism of Linggui Zhugan decoction in ameliorating chronic heart failure after myocardial infarction via HIF-1α/HO-1 signaling pathway
10.19540/j.cnki.cjcmm.20240718.401 · 2024 · External reference
Resveratrol improves survival, hemodynamics and energetics in a rat model of hypertension leading to heart failure
10.1371/journal.pone.0026391 · 2011 · External reference
Resveratrol improves myocardial perfusion in a swine model of hypercholesterolemia and chronic myocardial ischemia
10.1161/circulationaha.109.920132 · 2010 · External reference
A gene network regulating lysosomal biogenesis and function
10.1126/science.1174447 · 2009 · External reference
TFEB links autophagy to lysosomal biogenesis
10.1126/science.1204592 · 2011 · External reference
Plantamajoside attenuates isoproterenol-induced cardiac hypertrophy associated with the HDAC2 and AKT/GSK-3β signaling pathway
10.1016/j.cbi.2019.04.024 · 2019 · External reference
LAMP2-FLOT2 interaction enhances autophagosome-lysosome fusion to protect the septic heart in response to ILC2
10.1080/15548627.2025.2469207 · 2025 · External reference
Traditional Chinese medicine enhances myocardial metabolism during heart failure
10.1016/j.biopha.2021.112538 · 2022 · External reference
Astragaloside IV prevents acute myocardial infarction by inhibiting the TLR4/MyD88/NF-κB signaling pathway
10.1111/jfbc.13757 · 2021 · External reference
Mitochondria-derived vesicles with bioenergetic units from brown adipose tissue attenuate cardiac remodeling post-myocardial infarction
10.1038/s41467-026-73388-3 · 2026 · External reference
Oxidative stress: a concept in redox biology and medicine
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