Research graph
References from Natural products targeting mitochondrial homeostasis: a four-dimensional framework integrating dynamics, mitophagy, pharmacokinetics, and translational safety. Local targets link to admitted publications; unresolved targets remain external evidence.
DRP1: at the crossroads of dysregulated mitochondrial dynamics and altered cell signaling in cancer cells
10.1021/acsomega.3c06547 · 2023 · External reference
Caffeic acid phenethyl ester as a protective agent against nephrotoxicity and/or oxidative kidney damage: a detailed systematic review
10.1155/2014/561971 · 2014 · External reference
Evaluation of acute and sub-acute toxicity of selected traditional antiurolithiatic medicinal plant extracts in wistar albino rats
10.1016/j.toxrep.2020.10.001 · 2020 · External reference
Caffeic acid phenethyl ester counteracts doxorubicin-induced chemobrain in sprague-dawley rats: emphasis on the modulation of oxidative stress and neuroinflammation
10.1016/j.neuropharm.2020.108334 · 2020 · External reference
Bioavailability of epigallocatechin gallate administered with different nutritional strategies in healthy volunteers
10.3390/antiox9050440 · 2020 · External reference
The effect of polyphenols on kidney disease: targeting mitochondria
10.3390/nu14153115 · 2022 · External reference
Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors
10.1038/nbt1328 · 2007 · External reference
Risk assessment of chlorogenic and isochlorogenic acids in coffee by-products
10.3390/molecules28145540 · 2023 · External reference
Curcumin promotes apoptosis of liver cancer cells by down-regulating WNT/β-catenin
10.1166/mex.2023.2474 · 2023 · External reference
Multiple effects of CDK4/6 inhibition in cancer: from cell cycle arrest to immunomodulation
10.1016/j.bcp.2019.113676 · 2019 · External reference
Alterations in mitochondrial quality control in alzheimer's disease
10.3389/fncel.2016.00024 · 2016 · External reference
Epigallocatechin gallate (EGCG): pharmacological properties, biological activities and therapeutic potential
10.3390/molecules30030654 · 2025 · External reference
Development of a population pharmacokinetic model characterizing the tissue distribution of resveratrol after administration by different routes and doses in rats
10.3390/nu17010181 · 2025 · External reference
INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division
10.1083/jcb.201709111 · 2018 · External reference
Fusion and fission: interlinked processes critical for mitochondrial health
10.1146/annurev-genet-110410-132529 · 2012 · External reference
FAK regulates cardiomyocyte mitochondrial fission and function through DRP1
10.1111/febs.16263 · 2021 · External reference
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
10.1083/jcb.200211046 · 2003 · External reference
Fructus ligustri lucidi in osteoporosis: a review of its pharmacology, phytochemistry, pharmacokinetics and safety
10.3390/molecules22091469 · 2017 · External reference
Paeonol nanoemulsion for enhanced oral bioavailability: optimization and mechanism
10.2217/nnm-2017-0277 · 2018 · External reference
Sanggenon C suppresses tumorigenesis of gastric cancer by blocking ERK-DRP1-mediated mitochondrial fission
10.1021/acs.jnatprod.2c00524 · 2022 · External reference
The multifaceted roles of natural products in mitochondrial dysfunction
10.3389/fphar.2023.1093038 · 2023 · External reference
Mitochondrial dynamics in health and disease: mechanisms and potential targets
10.1038/s41392-023-01547-9 · 2023 · External reference
Design, synthesis, and pharmacological evaluation of novel benzothiazole derivatives targeting LCK in acute lymphoblastic leukemia
10.1016/j.bioorg.2024.107180 · 2024 · External reference
Gastrodin alleviates mitochondrial dysfunction by regulating SIRT3-mediated TFAM acetylation in vascular dementia
10.1016/j.phymed.2024.155369 · 2024 · External reference
Gastrodin protects H9c2 cardiomyocytes against oxidative injury by ameliorating imbalanced mitochondrial dynamics and mitochondrial dysfunction
10.1038/s41401-020-0382-x · 2020 · External reference
Polyphenol (−)-epigallocatechin gallate (EGCG) mitigated kidney injury by regulating metabolic homeostasis and mitochondrial dynamics involvement with Drp1-mediated mitochondrial fission in mice
10.1016/j.fct.2024.114906 · 2024 · External reference
Cocaine-induced neuron subtype mitochondrial dynamics through Egr3 transcriptional regulation
10.1186/s13041-021-00809-6 · 2021 · External reference
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
10.1038/nrm3722 · 2013 · External reference
Flavonoids as therapeutic agents in Alzheimer's and Parkinson's diseases: a systematic review of preclinical evidences
10.1155/2018/7043213 · 2018 · External reference
The effects of baicalein and baicalin on mitochondrial function and dynamics: a review
10.1016/j.phrs.2015.08.021 · 2015 · External reference
The BH3-only proteins BIM and PUMA are not critical for the reticulocyte apoptosis caused by loss of the pro-survival protein BCL-XL
10.1038/cddis.2017.304 · 2017 · External reference
Chicoric acid attenuated renal tubular injury in HFD-induced chronic kidney disease mice through the promotion of mitophagy via the Nrf2/PINK/Parkin pathway
10.1021/acs.jafc.1c07795 · 2022 · External reference
Paeonol protects against doxorubicin-induced cardiotoxicity by promoting MFN2-mediated mitochondrial fusion through activating the PKCε-Stat3 pathway
10.1016/j.jare.2022.07.002 · 2023 · External reference
Rg1 prevents myocardial hypoxia/reoxygenation injury by regulating mitochondrial dynamics imbalance via modulation of glutamate dehydrogenase and mitofusin 2
10.1016/j.mito.2015.11.003 · 2016 · External reference
The mitochondrial dynamism-mitophagy-cell death interactome: multiple roles performed by members of a mitochondrial molecular ensemble
10.1161/circresaha.116.303554 · 2015 · External reference
VPS13D interacts with VCP/p97 and negatively regulates endoplasmic reticulum-mitochondria interactions
10.1091/mbc.e21-03-0097 · 2021 · External reference
DRP1 regulates mitochondrial dysfunction and dysregulated metabolism in ischemic injury via Clec16a-BAX-and GSH-dependent pathways
10.1038/s41419-020-2461-9 · 2020 · External reference
The protective effect of vitexin on hypertensive nephropathy rats
10.1159/000540618 · 2024 · External reference
Pharmacokinetics and excretion of berberine and its nine metabolites in rats
10.3389/fphar.2020.594852 · 2021 · External reference
The dynamic equilibrium between the protective and toxic effects of matrine in the development of liver injury: a systematic review and meta-analysis
10.3389/fphar.2024.1315584 · 2024 · External reference
Punicalagin protects against diabetic cardiomyopathy by promoting OPA1-mediated mitochondrial fusion via regulating PTP1B-Stat3 pathway
10.1089/ars.2020.8248 · 2021 · External reference
Hepataprotective effects of ginsenoside Rg1 - a review
10.1016/j.jep.2017.04.012 · 2017 · External reference
2-Deoxy-Rh2: a novel ginsenoside derivative, as dual-targeting anti-cancer agent via regulating apoptosis and glycolysis
10.1016/j.biopha.2020.109891 · 2020 · External reference
Sensory deficit screen identifies nsf mutation that differentially affects SNARE recycling and quality control
10.1016/j.celrep.2023.112345 · 2023 · External reference
Regulation of reactive oxygen species and the role of mitochondrial apoptotic-related genes in rheumatoid arthritis
10.1038/s41598-025-85460-x · 2025 · External reference
Pharmacokinetics of the material basis compounds of Tianshu capsule in treating migraine
10.1016/j.jep.2024.119040 · 2025 · External reference
Modulation of dynamin-related protein 1 (DRP1) function by increased O-linked-β-N-acetylglucosamine modification (O-GlcNAc) in cardiac myocytes
10.1074/jbc.m112.390682 · 2012 · External reference
True-to-scale DNA-density maps correlate with major accessibility differences between active and inactive chromatin
10.1016/j.celrep.2023.112567 · 2023 · External reference
Pharmacokinetics and pharmacodynamics of bioactive compounds in penyanqing preparation in THP-1 inflammatory cells induced by lipopolysaccharide
10.1186/s12906-022-03784-x · 2022 · External reference
A case study of percutaneous epidural stimulation to enable motor control in two men after spinal cord injury
10.1038/s41467-023-37845-7 · 2023 · External reference
Caffeoylquinic acids in Centella asiatica protect against amyloid-β toxicity
10.3233/jad-131913 · 2014 · External reference
Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria
10.1074/jbc.m400920200 · 2004 · External reference
The status and trends of mitochondrial dynamics research: a global bibliometric and visualized analysis
10.1007/s10863-023-09959-6 · 2023 · External reference
Rosmarinic acid: a naturally occurring plant-based agent prevents impaired mitochondrial dynamics and apoptosis in ultraviolet-B-irradiated human skin cells
10.1111/php.13533 · 2022 · External reference
CaM kinase Iα-induced phosphorylation of DRP1 regulates mitochondrial morphology
10.1083/jcb.200802164 · 2008 · External reference
Synthesis, characterization and efficacy of mitochondrial targeted delivery of TPP-curcumin in rotenone-induced toxicity
10.1007/s40199-019-00283-2 · 2019 · External reference
Green tea and benign gynecologic disorders: a new trick for an old beverage?
10.3390/nu15061439 · 2023 · External reference
Rosmarinic acid - human pharmacokinetics and health benefits
10.1055/a-1301-8648 · 2020 · External reference
Miro1 marks Parkinson's disease subset and Miro1 reducer rescues neuron loss in Parkinson's models
10.1016/j.cmet.2019.08.023 · 2019 · External reference
Pharmacokinetics, tissue distribution and excretion of paeonol and its major metabolites in rats provide a further insight into paeonol effectiveness
10.3389/fphar.2020.00190 · 2020 · External reference
An overview of pharmacological activities of baicalin and its aglycone baicalein: new insights into molecular mechanisms and signaling pathways
10.22038/ijbms.2022.60380.13381 · 2022 · External reference
TBK1-mediated DRP1 phosphorylation orchestrates mitochondrial dynamics and autophagy activation in osteoarthritis
10.1038/s41401-022-00967-7 · 2023 · External reference
Natural products for kidney disease treatment: focus on targeting mitochondrial dysfunction
10.3389/fphar.2023.1142001 · 2023 · External reference
Hypoxia leads to gill endoplasmic reticulum stress and disruption of mitochondrial homeostasis in grass carp (Ctenopharyngodon idella): mitigation effect of thiamine
10.1016/j.jhazmat.2024.134005 · 2024 · External reference
Carica papaya ameliorates allergic asthma via down-regulation of IL-4, IL-5, eotaxin, TNF-α, NF-κB, and iNOS levels
10.1016/j.phymed.2017.05.006 · 2017 · External reference
Different approaches to modeling analysis of mitochondrial swelling
10.1016/j.mito.2017.08.010 · 2018 · External reference
Curcumin loaded pH-sensitive hybrid lipid/block copolymer nanosized drug delivery systems
10.1016/j.ejps.2015.07.019 · 2015 · External reference
Alterations in energy metabolism, mitochondrial function and redox homeostasis in GK diabetic rat tissues treated with aspirin
10.3390/life12111860 · 2022 · External reference
Precision medicine, AI, and the future of personalized health care
10.1111/cts.12884 · 2020 · External reference
The role of gut microbiota-mitochondria crosstalk in neurodegeneration: underlying mechanisms and potential therapies
10.4103/nrr.nrr-d-24-01419 · 2025 · External reference
Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats
10.1007/s00280-010-1525-4 · 2010 · External reference
Mechanisms by which microbiome-derived metabolites exert their impacts on neurodegeneration
10.1016/j.chembiol.2024.12.005 · 2025 · External reference
Mechanistic insight of curcumin: a potential pharmacological candidate for epilepsy
10.3389/fphar.2024.1430169 · 2025 · External reference
The effects of green tea on obesity and type 2 diabetes
10.4093/dmj.2013.37.3.173 · 2013 · External reference
Structure and function of mitochondrial membrane protein complexes
10.1186/s12915-015-0201-x · 2015 · External reference
Ginsenosides attenuate bioenergetics and morphology of mitochondria in cultured PC12 cells under the insult of amyloid beta-peptide
10.1016/j.jgr.2020.10.002 · 2021 · External reference
Effects of isochlorogenic acid A on mitochondrial dynamics imbalance and RLR damage in PAM cells induced by combined mycotoxins
10.1016/j.tox.2023.154292 · 2024 · External reference
Correlation of bioactive marker compounds of an orally applied Morus alba root bark extract with toxicity and efficacy in BALB/c mice
10.3389/fphar.2023.1200201 · 2023 · External reference
Sulforaphane improves syncytiotrophoblast mitochondrial function after in vitro hypoxic and superoxide injury
10.1016/j.placenta.2020.05.010 · 2020 · External reference
Feature replacement methods enable reliable home video analysis for machine learning detection of autism
10.1038/s41598-020-66615-4 · 2020 · External reference
Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis
10.1002/hep.32434 · 2022 · External reference
Quercetin regulates inflammation, oxidative stress, apoptosis, and mitochondrial structure and function in H9C2 cells by promoting PVT1 expression
10.1016/j.acthis.2021.151740 · 2021 · External reference
An efficient photochemotherapy nanoplatform based on the endogenous biosynthesis of photosensitizer in macrophage-derived extracellular vesicles
10.1016/j.biomaterials.2021.121216 · 2021 · External reference
Autophagy: an important target for natural products in the treatment of bone metabolic diseases
10.3389/fphar.2022.1085168 · 2022 · External reference
Correction: NCSTN promotes hepatocellular carcinoma cell growth and metastasis via β-catenin activation in a Notch1/AKT-dependent manner
10.1186/s13046-023-02765-0 · 2023 · External reference
Application of novel degraders employing autophagy for expediting medicinal research
10.1021/acs.jmedchem.2c01774 · 2023 · External reference
Echinacoside, an inestimable natural product in treatment of neurological and other disorders
10.3390/molecules23051213 · 2018 · External reference
Ferulic acid inhibits LPS-induced apoptosis in bovine mammary epithelial cells by regulating the NF-κB and Nrf2 signalling pathways to restore mitochondrial dynamics and ROS generation
10.1186/s13567-021-00892-0 · 2021 · External reference
A review
10.4103/wjtcm.wjtcm_50_22 · 2022 · External reference
Comparative transcriptome analyses provide new insights into the evolution of divergent thermal resistance in two eel gobies
10.3390/cimb46020011 · 2023 · External reference
Natural products targeting RAS by multiple mechanisms and its therapeutic potential in cancer: an update since 2020
10.1016/j.phrs.2024.108961 · 2025 · External reference
Mitochondrial dynamics
10.1046/j.1469-8137.2003.00994.x · 2003 · External reference
GC-TOF/MS-based metabolomic profiling of estrogen deficiency-induced obesity in ovariectomized rats
10.1038/aps.2010.194 · 2011 · External reference
DUSP6 SUMOylation protects cells from oxidative damage via direct regulation of DRP1 dephosphorylation
10.1126/sciadv.aaz0365 · 2020 · External reference
Lonicerae Japonicae Flos with the homology of medicine and food: a review of active ingredients, anticancer mechanisms, pharmacokinetics, quality control, toxicity and applications
10.3389/fonc.2024.1383518 · 2024 · External reference
Artemisinin-type drugs for the treatment of hematological malignancies
10.1007/s00280-020-04036-2 · 2020 · External reference
Nanotherapeutic approaches to target mitochondria in cancer
10.1016/j.lfs.2021.119799 · 2021 · External reference
Novel nutraceutic therapies for the treatment of metabolic syndrome
10.4239/wjd.v7.i7.118 · 2016 · External reference
Detailed analysis of Mdivi-1 effects on complex I and respiratory supercomplex assembly
10.1038/s41598-024-52825-3 · 2024 · External reference
Natural 2′,4-dihydroxy-4′,6′-dimethoxy chalcone isolated from Chromolaena tacotana inhibits breast cancer cell growth through autophagy and mitochondrial apoptosis
10.3390/plants13091152 · 2024 · External reference
Resveratrol regulates the expression of genes involved in CoQ synthesis in liver in mice fed with high fat diet
10.3390/antiox9121173 · 2020 · External reference
Adenosine A1 receptors contribute to mitochondria vulnerability to pro-oxidant stressors
10.1016/j.mito.2010.03.004 · 2010 · External reference
Astaxanthin carotenoid modulates oxidative stress in adipose-derived stromal cells isolated from equine metabolic syndrome affected horses by targeting mitochondrial biogenesis
10.3390/biom12091353 · 2022 · External reference
Noncanonical transnitrosylation network contributes to synapse loss in alzheimer's disease
10.1126/science.aaw0843 · 2021 · External reference
Determination of trifolirhizin in rat plasma by UPLC: application to a pharmacokinetic study
10.1016/j.jchromb.2015.03.028 · 2015 · External reference
Therapeutic and nutraceutical potential of rosmarinic acid - cytoprotective properties and pharmacokinetic profile
10.1080/10408398.2012.677872 · 2015 · External reference
Mitochondria: in sickness and in health
10.1016/j.cell.2012.02.035 · 2012 · External reference
Molecular mechanisms and physiological functions of mitophagy
10.15252/embj.2020104705 · 2021 · External reference
Protective effect of curcumin against the liver toxicity caused by propanil in rats
10.1155/2014/850915 · 2014 · External reference
Trauma of the frontal region is influenced by the volume of frontal sinuses: a finite element study
10.3389/fphys.2017.00658 · 2017 · External reference
Potential modulation of human NAD(P)H:quinone oxidoreductase 1 (NQO1) by EGCG and its metabolites—a systematic computational study
10.1021/acs.chemrestox.0c00288 · 2020 · External reference
Mitochondrial transplantation as a novel therapeutic strategy for mitochondrial diseases
10.3390/ijms22094793 · 2021 · External reference
Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration
10.1038/ncb2488 · 2012 · External reference
3′-O-β-D-glucopyranosyl-α,4,2′,4′,6′-pentahydroxy-dihydrochalcone, from bark of eysenhardtia polystachya prevents diabetic nephropathy via inhibiting protein glycation in STZ-nicotinamide induced diabetic mice
10.3390/molecules24030440 · 2019 · External reference
Function of green tea catechins in the brain: epigallocatechin gallate and its metabolites
10.3390/ijms20153633 · 2019 · External reference
Mitophagy and quality control mechanisms in mitochondrial maintenance
10.1016/j.cub.2018.01.004 · 2018 · External reference
The mitochondria-endoplasmic reticulum contact sites: a signalling platform for cell death
10.1016/j.ceb.2017.03.007 · 2017 · External reference
Curcuma wenyujin extract alleviates cognitive deficits and restrains pyroptosis through PINK1/Parkin mediated autophagy in alzheimer's disease
10.1016/j.phymed.2024.155637 · 2025 · External reference
Toxicology effects of Berberis vulgaris (barberry) and its active constituent, berberine: a review
10.22038/ijbms.2017.8679 · 2017 · External reference
Inhibition of DRP1-dependent mitochondrial fission by natural compounds as a therapeutic strategy for organ injuries
10.1016/j.phrs.2022.106664 · 2023 · External reference
Quercetin induces mitochondrial biogenesis through activation of HO-1 in HepG2 cells
10.1155/2013/154279 · 2013 · External reference
Editorial of the article
10.1016/j.bbadis.2017.06.012 · 2017 · External reference
Resveratrol ameliorates mitochondrial elongation via DRP1/Parkin/PINK1 signaling in senescent-like cardiomyocytes
10.1155/2017/4175353 · 2017 · External reference
Endoplasmic reticulum-mitochondria contacts: function of the junction
10.1038/nrm3440 · 2012 · External reference
Curcumin alleviates LPS-induced intestinal homeostatic imbalance through reshaping gut microbiota structure and regulating group 3 innate lymphoid cells in chickens
10.1039/d2fo02177h · 2022 · External reference
Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents
10.1038/nm.4132 · 2016 · External reference
Cellular ATP demand creates metabolically distinct subpopulations of mitochondria
10.1038/s41586-024-07349-7 · 2024 · External reference
Triazolopyrimidines are microtubule-stabilizing agents that bind the vinca inhibitor site of tubulin
10.1016/j.chembiol.2017.05.024 · 2017 · External reference
Tracking cancer drugs in living cells by thermal profiling of the proteome
10.1126/science.1255784 · 2014 · External reference
Biopharmaceutical profiling of anti-infective sanggenons from Morus alba root bark for inhalation administration
10.1016/j.ijpx.2024.100226 · 2024 · External reference
Reduced mitochondrial calcium uptake in macrophages is a major driver of inflammaging
10.1038/s43587-023-00433-0 · 2023 · External reference
Bioavailability and safety study of resveratrol 500 mg tablets in healthy male and female volunteers
10.3892/etm.2015.2865 · 2016 · External reference
Pharmacokinetic interactions between 20(S)-ginsenoside Rh2 and the HIV protease inhibitor ritonavir in vitro and in vivo
10.1038/aps.2013.84 · 2013 · External reference
Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults
10.1016/j.xcrm.2022.100633 · 2022 · External reference
Effect of apigenin on seizure susceptibility, parvalbumin immunoreactivity, and GABAA receptor expression in the hippocampal neurons in mice
10.1016/j.ejphar.2024.175325 · 2025 · External reference
The protective effect of edaravone on TDP-43 plus oxidative stress-induced neurotoxicity in neuronal cells: analysis of its neuroprotective mechanisms using RNA sequencing
10.3390/ph15101220 · 2022 · External reference
Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission
10.1074/jbc.m607279200 · 2007 · External reference
Editorial: mitochondrial dysfunction and neurodegeneration
10.3389/fnins.2019.01372 · 2019 · External reference
Ellagic acid toxicity and interaction with benzo[a]pyrene and benzo[a]pyrene 7,8-dihydrodiol in human bronchial epithelial cells
10.1007/bf00117707 · 1986 · External reference
A UHPLC-MS/MS method for simultaneous determination of twelve constituents from erigeron breviscapus extract in rat plasma: application to a pharmacokinetic study
10.1016/j.jchromb.2017.01.010 · 2017 · External reference
The role of DRP1 in mitophagy and cell death in the heart
10.1016/j.yjmcc.2020.04.025 · 2020 · External reference
Mitochondrial movers and shapers: recent insights into regulators of fission, fusion and transport
10.1016/j.ceb.2023.102126 · 2023 · External reference
Plasma gel matrix as a promising carrier of epigallocatechin gallate for regenerative medicine
10.3390/jfb15050206 · 2024 · External reference
Quercetin and cancer: new insights into its therapeutic effects on ovarian cancer cells
10.1186/s13578-020-00390-2 · 2020 · External reference
Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome
10.1016/j.bbadis.2012.12.011 · 2013 · External reference
Neuroprotective mechanisms of luteolin in glutamate-induced oxidative stress and autophagy-mediated neuronal cell death
10.1038/s41598-024-62432-y · 2024 · External reference
Pharmacokinetics, tissue distribution, and plasma protein binding study of chicoric acid by HPLC-MS/MS
10.1016/j.jchromb.2016.08.029 · 2016 · External reference
The burgeoning role of cytochrome P450-mediated vitamin D metabolites against colorectal cancer
10.1016/j.phrs.2018.04.010 · 2018 · External reference
Isochlorogenic acid (ICGA): natural medicine with potentials in pharmaceutical developments
10.1016/s1875-5364(20)30098-9 · 2020 · External reference
Determination of the dissociation constants of 16 active ingredients in medicinal herbs using a liquid-liquid equilibrium method
10.3390/separations8050056 · 2021 · External reference
Optimization of NAMPT activators to achieve in vivo neuroprotective efficacy
10.1016/j.ejmech.2022.114301 · 2022 · External reference
Deciphering resveratrol's role in modulating pathological pain: from molecular mechanisms to clinical relevance
10.1002/ptr.8007 · 2023 · External reference
Epigallocatechin-3-gallate and its nanoformulation in cervical cancer therapy: the role of genes, microRNA and DNA methylation patterns
10.1186/s12935-023-02877-9 · 2023 · External reference
Targeted energy metabolomics combined with spatial metabolomics study on the efficacy of guhong injection against cerebral ischemia reperfusion
10.1007/s12035-023-03403-x · 2023 · External reference
Role of mitochondrial alterations in human cancer progression and cancer immunity
10.1186/s12929-022-00875-y · 2023 · External reference
Betel quid may stimulate oral submucous fibrosis by inducing increased mitochondrial reactive oxygen species generation via copper overload
10.1016/j.mehy.2023.111170 · 2023 · External reference
Development of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for characterizing pomegranate extract pharmacokinetics in humans
10.1016/j.jpba.2023.115317 · 2023 · External reference
Mitochondrial dynamics and mitochondrial autophagy: molecular structure, orchestrating mechanism and related disorders
10.1016/j.mito.2023.12.004 · 2024 · External reference
Rapamycin inhibits B16 melanoma cell viability in vitro and in vivo by inducing autophagy and inhibiting the mTOR/p70-S6K pathway
10.3892/ol.2023.14127 · 2024 · External reference
Akkermansia muciniphila and its metabolite propionic acid maintains neuronal mitochondrial division and autophagy homeostasis during alzheimer's disease pathologic process via GPR41 and GPR43
10.1186/s40168-025-01920-4 · 2025 · External reference
Salidroside ameliorates ischemia-induced neuronal injury through AMPK-dependent and -independent pathways to maintain mitochondrial quality control
10.1142/s0192415x22500561 · 2022 · External reference
Mitochondrial diseases: from molecular mechanisms to therapeutic advances
10.1038/s41392-025-02024-0 · 2025 · External reference
Mitochondria-lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis
10.1038/nature25486 · 2018 · External reference
Baicalin improves cardiac outcome and survival by suppressing DRP1-mediated mitochondrial fission after cardiac arrest-induced myocardial damage
10.1155/2021/6643616 · 2021 · External reference
Flazin improves mitochondrial dynamics in renal tubular epithelial cells under oxidative stress
10.1016/j.fbio.2023.103150 · 2023 · External reference
Formation of EGCG oxidation self-assembled nanoparticles and their antioxidant activity in vitro and hepatic REDOX regulation activity in vivo
10.1039/d3fo03542b · 2024 · External reference
Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation
10.1038/s42255-023-00932-9 · 2024 · External reference
Extraction, identification, and antioxidant and anticancer tests of seven dihydrochalcones from malus 'Red Splendor' fruit
10.1016/j.foodchem.2017.03.090 · 2017 · External reference
Chelidonine selectively inhibits the growth of gefitinib-resistant non-small cell lung cancer cells through the EGFR-AMPK pathway
10.1016/j.phrs.2020.104982 · 2020 · External reference
Small-molecule dual inhibitors targeting heat shock protein 90 for cancer targeted therapy
10.1016/j.bioorg.2023.106598 · 2023 · External reference
Orally hierarchical targeting delivery systems relieve colitis by protecting host mitochondria and modulating gut microbiota
10.1016/j.nantod.2024.102997 · 2024 · External reference
Curcumin protects rat heart mitochondria against anoxia-reoxygenation induced oxidative injury
10.1139/cjpp-2012-0368 · 2013 · External reference
Pharmacokinetic study of ferulic acid following transdermal or intragastric administration in rats
10.1208/s12249-020-01756-4 · 2020 · External reference
Astaxanthin inhibits H2O2-induced excessive mitophagy and apoptosis in SH-SY5Y cells by regulation of Akt/mTOR activation
10.3390/md22030296 · 2024 · External reference
Vitexin mitigates myocardial ischemia/reperfusion injury in rats by regulating mitochondrial dysfunction via Epac1-Rap1 signaling
10.1155/2021/8835388 · 2021 · External reference
Mitophagy-related regulated cell death: molecular mechanisms and disease implications
10.1038/s41419-024-06660-x · 2024 · External reference
Mitochondrial dynamics in health and disease
10.1002/1873-3468.14095 · 2021 · External reference
Toxicological studies of Orthosiphon stamineus (misai kucing) standardized ethanol extract in combination with gemcitabine in athymic nude mice model
10.1016/j.jare.2018.10.004 · 2019 · External reference
Rhein ameliorates cognitive impairment in an APP/PS1 transgenic mouse model of alzheimer's disease by relieving oxidative stress through activating the SIRT1/PGC-1α pathway
10.1155/2022/5996587 · 2022 · External reference
A systematic review of the pharmacology, toxicology and pharmacokinetics of matrine
10.3389/fphar.2020.01060 · 2020 · External reference
A potent protective effect of baicalein on liver injury by regulating mitochondria-related apoptosis
10.1007/s10495-020-01611-0 · 2020 · External reference
Modulating mitofusins to control mitochondrial function and signaling
10.1038/s41467-021-27893-8 · 2022 · External reference
Sophorae Tonkinensis Radix et Rhizoma: a comprehensive review of the ethnopharmacology, phytochemistry, pharmacology, pharmacokinetics, toxicology and detoxification strategy
10.1016/j.jep.2024.118945 · 2025 · External reference
The DRP1-mediated mitochondrial fission protein interactome as an emerging core player in mitochondrial dynamics and cardiovascular disease therapy
10.3390/ijms24076153 · 2023 · External reference
Bioactivity and chemical synthesis of caffeic acid phenethyl ester and its derivatives
10.3390/molecules191016458 · 2014 · External reference
Metformin activates AMPK through the lysosomal pathway
10.1016/j.cmet.2016.09.013 · 2016 · External reference
Resveratrol reduces oxidative stress and apoptosis in podocytes via Sir2-related enzymes, sirtuins1 (SIRT1)/peroxisome proliferator-activated receptor γ co-activator 1α (PGC-1α) axis
10.12659/msm.912661 · 2019 · External reference
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