References

Independent and combined effects of astaxanthin and omega-3 on behavioral deficits and molecular changes in a prenatal valproic acid model of autism in rats

10.1080/1028415x.2023.2239575 · 2024 · External reference

Fighting autism with fatty acids: maternal omega-3 shields the developing brain from VPA-induced behavioral and neurochemical damage

10.3390/biology14081065 · 2025 · External reference

Promising therapeutic effects of high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) in addressing autism spectrum disorder induced by valproic acid

10.3389/fnins.2024.1385488 · 2024 · External reference

Perindopril ameliorates sodium valproate-induced rat model of autism: involvement of sirtuin-1, JAK2/STAT3 axis, PI3K/Akt/GSK-3β pathway, and PPAR-gamma signaling

10.3390/medicina60111802 · 2024 · External reference

Unresolved reference

2013 · External reference

Increased serotonin levels and unchanged glutamate and GABA levels in thalamic microdialysates despite reduced cell numbers in a valproic acid-induced autism model

10.1007/s11064-024-04299-2 · 2025 · External reference

Rodent models for psychiatric disorders: problems and promises

10.1186/s42826-020-00039-z · 2020 · External reference

Genetic machinery which accompanies metaplasticity operates differentially in experimental model of autism

10.1002/jdn.10398 · 2025 · External reference

Animal model of autism induced by valproic acid combined with maternal deprivation: sex-specific effects on inflammation and oxidative stress

10.1007/s12035-024-04491-z · 2025 · External reference

Immune system dysfunction and inflammation in aging Shank3b mutant mice, a model of autism spectrum disorder

10.3389/fimmu.2024.1447385 · 2024 · External reference

Prenatal valproic acid induces autistic‐like behaviors in rats via dopaminergic modulation in nigrostriatal and mesocorticolimbic pathways

10.1111/jnc.16282 · 2025 · External reference

Autism risk factors: genes, environment, and gene-environment interactions

10.31887/dcns.2012.14.3/pchaste · 2012 · External reference

Chinese acupuncture: a potential treatment for autism rat model via improving synaptic function

10.1016/j.heliyon.2024.e37130 · 2024 · External reference

VPA-induced autism impairs memory ability through disturbing neural oscillatory patterns in offspring rats

10.1007/s11571-023-09996-2 · 2024 · External reference

Wnt/β-catenin signaling in cerebral cortical development

10.4161/org.4.2.5852 · 2008 · External reference

Soluble epoxide hydrolase deletion rescues behavioral and synaptic deficits by AMPK-mTOR pathway in autism animals

10.1016/j.pnpbp.2024.111190 · 2025 · External reference

Effects of cannabidiol isolated or in association with risperidone in an animal model of autism

10.1002/dneu.22955 · 2025 · External reference

The impact of astroglia Kir4.1 channel dysfunction on neuronal activity and autism‐related behavioral abnormalities

10.1002/glia.24676 · 2025 · External reference

Rapid effects of valproic acid on the fetal brain transcriptome: implications for brain development and autism

10.1038/s41398-024-03179-1 · 2024 · External reference

Probiotic treatment reduces the autistic-like excitation/inhibition imbalance in juvenile hamsters induced by orally administered propionic acid and clindamycin

10.1007/s11011-018-0212-8 · 2018 · External reference

Head circumference as an early predictor of autism symptoms in younger siblings of children with autism spectrum disorder

10.1007/s10803-007-0495-9 · 2008 · External reference

The potential ameliorative effect of mesenchymal stem cells-derived exosomes on cerebellar histopathology and their modifying role on PI3k-mTOR signaling in rat model of autism spectrum disorder

10.1007/s10735-024-10335-w · 2025 · External reference

Epigenetics and autism spectrum disorder: is there a correlation

10.3389/fncel.2018.00078 · 2018 · External reference

Integrating 16S rRNA gene sequencing and metabolomics analysis to reveal the mechanism of L-proline in preventing autism-like behavior in mice

10.3390/nu17020247 · 2025 · External reference

Neuroprotective effects of apigenin on prenatal valproic acid-induced autism spectrum disorder in rats

10.1016/j.ibneur.2024.10.003 · 2024 · External reference

Comparative effect of atorvastatin and risperidone on modulation of TLR4/NF-κB/NOX-2 in a rat model of valproic acid-induced autism

10.1186/s12993-024-00250-1 · 2024 · External reference

Etiology of autism the complexity of risk factors in autism spectrum disorder

10.5772/59109 · 2015 · External reference

Gestational VPA exposure reduces the density of juxtapositions between TH+ axons and calretinin or calbindin expressing cells in the ventrobasal forebrain of neonatal mice

10.3389/fnana.2024.1426042 · 2024 · External reference

Embryonic exposure to environmental factors drives transmitter switching in the neonatal mouse cortex causing autistic-like adult behavior

10.1073/pnas.2406928121 · 2024 · External reference

<scp>tVNS</scp> alters inflammatory response in adult VPA ‐induced mouse model of autism: evidence for sexual dimorphism

10.1002/2211-5463.13889 · 2025 · External reference

Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons

10.1006/mcne.2002.1117 · 2002 · External reference

Maternal immune activation and neuroinflammation in human neurodevelopmental disorders

10.1038/s41582-021-00530-8 · 2021 · External reference

NEAT1 promotes valproic acid-induced autism spectrum disorder by recruiting YY1 to regulate UBE3A transcription

10.1007/s12035-024-04309-y · 2025 · External reference

Autism spectrum disorder: definition, epidemiology, causes, and clinical evaluation

10.21037/tp.2019.09.09 · 2020 · External reference

Autistic-like behaviour and changes in thalamic cell numbers a rat model of valproic acid-induced autism; a behavioural and stereological study

10.1016/j.brainres.2024.149047 · 2024 · External reference

BDNF and GSK-3beta expression changes underlie the beneficial effects of crocin on behavioral alterations in a rat model of autism induced by prenatal valproic acid administration

10.1007/s00210-024-03777-2 · 2025 · External reference

Animal models of autism spectrum disorders and behavioral techniques of their examination

10.1007/s11062-017-9613-2 · 2016 · External reference

Striatal interneuron imbalance in a valproic acid-induced model of autism in rodents is accompanied by atypical somatosensory processing

10.1523/eneuro.0326-24.2024 · 2024 · External reference

Lipopolysaccharide induces neuroinflammation in a valproic acid male model of autism

10.1016/j.brainresbull.2024.111154 · 2025 · External reference

Valproic acid induces differentiation and inhibition of proliferation in neural progenitor cells via the beta-catenin-Ras-ERK-p21Cip/WAF1 pathway

10.1186/1471-2121-9-66 · 2008 · External reference

Region-specific brain volume changes emerge in adolescence in the valproic acid model of autism and parallel human findings

10.1159/000538932 · 2024 · External reference

Altered prefrontal and cerebellar parvalbumin neuron counts are associated with cognitive changes in male rats

10.1007/s00221-024-06902-y · 2024 · External reference

Adolescent treadmill exercise enhances hippocampal brain-derived neurotrophic factor (BDNF) expression and improves cognition in autism-modeled rats

10.1016/j.physbeh.2024.114638 · 2024 · External reference

Autism spectrum disorder-like behaviors induced by hyper-glutamatergic NMDA receptor signaling through hypo-serotonergic 5-HT1A receptor signaling in the prefrontal cortex in mice exposed to prenatal valproic acid

10.1038/s41386-024-02004-z · 2024 · External reference

Modeling autism-related disorders in mice with maternal immune activation (MIA)

10.1007/978-1-4939-9167-9_20 · 2019 · External reference

Unravelling the role of SHANK3 mutations in targeted therapies for autism spectrum disorders

10.1007/s44202-024-00223-5 · 2024 · External reference

Gastrointestinal problems in a valproic acid-induced rat model of autism: From maternal intestinal health to offspring intestinal function

10.5498/wjp.v14.i7.1095 · 2024 · External reference

Developmental trajectory of autistic‐like behaviors in a prenatal valproic acid rat model of autism

10.1002/dev.70008 · 2025 · External reference

Sortilin is associated with progranulin deficiency and autism‐like behaviors in valproic acid‐induced autism rats

10.1111/cns.70015 · 2024 · External reference

Administration of atosiban, an oxytocin receptor antagonist, ameliorates autistic-like behaviors in a female rat model of valproic acid-induced autism

10.1016/j.bbr.2024.115052 · 2024 · External reference

Microglia inversely regulate the level of perineuronal nets with the treatment of lipopolysaccharide and valproic acid

10.1016/j.neulet.2024.137992 · 2024 · External reference

Clostridium butyricum regulates intestinal barrier function via trek1 to improve behavioral abnormalities in mice with autism spectrum disorder

10.1186/s13578-024-01278-6 · 2024 · External reference

Oral edaravone ameliorates behavioral deficits and pathologies in a valproic acid-induced rat model of autism spectrum disorder

10.1016/j.neuropharm.2024.110089 · 2024 · External reference

Obliteration of a glycinergic projection to the medial geniculate in an animal model of autism

10.3389/fncel.2024.1465255 · 2024 · External reference

Critical evaluation of valproic acid-induced rodent models of autism: current and future perspectives

10.1007/s12031-022-02033-7 · 2022 · External reference

Transient CSF1R inhibition ameliorates behavioral deficits in Cntnap2 knockout and valproic acid-exposed mouse models of autism

10.1186/s12974-024-03259-5 · 2024 · External reference

Biomimetic nanoparticles with enhanced rapamycin delivery for autism spectrum disorder treatment via autophagy activation and oxidative stress modulation

10.7150/thno.95614 · 2024 · External reference

Prenatal valproate exposure affects cortical neurite branching, GABAergic markers, motor reflexes and ultrasonic vocalizations in the male rat pups

10.1111/jnc.70184 · 2025 · External reference

Sigma-1 receptor modulation by fluvoxamine ameliorates valproic acid-induced autistic behavior in rats: involvement of chronic ER stress modulation, enhanced autophagy and M1/M2 microglia polarization

10.1016/j.pnpbp.2024.111192 · 2025 · External reference

Continuous exercise training rescues hippocampal long-term potentiation in the VPA rat model of autism: Uncovering sex-specific effects

10.1016/j.neuroscience.2024.08.037 · 2024 · External reference

Construction of an animal model of autism based on interaction between cerebellar histological, immunohistochemical, and biochemical changes in adult male albino rat

10.1080/01913123.2024.2438382 · 2025 · External reference

Pharmacokinetic characterisation of a valproate autism spectrum disorder rat model in a context of co-exposure to α-Hexabromocyclododecane

10.1016/j.etap.2023.104343 · 2024 · External reference

Pharmacological intervention of behavioural traits and brain histopathology of prenatal valproic acid-induced mouse model of autism

10.1371/journal.pone.0308632 · 2024 · External reference

The valproic acid-induced rodent model of autism

10.1016/j.expneurol.2017.04.017 · 2018 · External reference

Benefits of bone marrow mesenchymal stem cells compared to their conditioned medium in valproic acid-induced autism in rats

10.1007/s11033-024-09292-0 · 2024 · External reference

Brain region–specific neural activation by low-dose opioid promotes social behavior

10.1172/jci.insight.182060 · 2024 · External reference

Investigating brain–gut microbiota dynamics and inflammatory processes in an autistic-like rat model using MRI biomarkers during childhood and adolescence

10.1016/j.neuroimage.2024.120899 · 2024 · External reference

Acute cannabidiol treatment reverses behavioral impairments induced by embryonic valproic acid exposure in male mice

10.1016/j.pbb.2024.173919 · 2025 · External reference

Prebiotic diet normalizes aberrant immune and behavioral phenotypes in a mouse model of autism spectrum disorder

10.1038/s41401-024-01268-x · 2024 · External reference

Development and evaluation of an autism pig model

10.1038/s41684-024-01475-3 · 2024 · External reference

Reversal of electrophysiological and behavioral deficits mediated by 5-HT7 receptor upregulation following LP-211 treatment in an autistic-like rat model induced by prenatal valproic acid exposure

10.1016/j.neuropharm.2024.110057 · 2024 · External reference

The neuroprotective effect of diosgenin in the rat valproic acid model of autism

10.1016/j.brainres.2024.148963 · 2024 · External reference

Prenatal exposure to valproic acid reduces synaptic δ-catenin levels and disrupts ultrasonic vocalization in neonates

10.1016/j.neuropharm.2024.109963 · 2024 · External reference

Spontaneous calcium transients recorded from striatal astrocytes in a preclinical model of autism

10.1007/s11064-024-04218-5 · 2024 · External reference

GABAergic control of neurite outgrowth and remodeling during development and adult neurogenesis: general rules and differences in diverse systems

10.3389/fncel.2010.00011 · 2010 · External reference

Aerobic exercise improves cognitive flexibility and modulates regional volume changes in a rat model of autism

10.1016/j.bbr.2024.115136 · 2024 · External reference

An alpha <scp> 5‐GABA A </scp> receptor positive allosteric modulator attenuates social and cognitive deficits without changing dopamine system hyperactivity in rats exposed to valproic acid in utero

10.1002/aur.3178 · 2024 · External reference

Human umbilical cord-derived mesenchymal stem cells alleviate valproate-induced immune stress and social deficiency in rats

10.3389/fpsyt.2024.1431689 · 2024 · External reference

Adult neurogenesis in the ventral hippocampus decreased among animal models of neurodevelopmental disorders

10.3389/fncir.2024.1504191 · 2024 · External reference

Pairing tones with vagus nerve stimulation improves brain stem responses to speech in the valproic acid model of autism

10.1152/jn.00325.2024 · 2024 · External reference

Vitamin C and gallic acid ameliorate motor dysfunction, cognitive deficits, and brain oxidative stress in a valproic acid‐induced model of autism

10.1002/brb3.70262 · 2025 · External reference

Prenatal valproate in rodents as a tool to understand the neural underpinnings of social dysfunctions in autism spectrum disorder

10.1016/j.neuropharm.2018.12.024 · 2019 · External reference

Impairments of social interaction in a valproic acid model in mice

10.3389/fnbeh.2024.1430267 · 2024 · External reference

Practice parameter for the assessment and treatment of children and adolescents with autism spectrum disorder

10.1016/j.jaac.2013.10.013 · 2014 · External reference

Low-frequency RTMS attenuates social impairment in the VPA-induced mouse model

10.1016/j.bbr.2024.115156 · 2024 · External reference

Restoration of nNOS expression rescues autistic-like phenotypes through normalization of AMPA receptor-mediated neurotransmission

10.1007/s12035-024-03997-w · 2024 · External reference

Taprenepag restores maternal–fetal interface homeostasis for the treatment of neurodevelopmental disorders

10.1186/s12974-024-03300-7 · 2024 · External reference

Prenatal exposure to valproic acid induces sex-specific alterations in rat cortical and hippocampal neuronal structure and function in vitro

10.1016/j.pnpbp.2024.111222 · 2025 · External reference

Salidroside ameliorates neuroinflammation in autistic rats by inhibiting NLRP3/Caspase-1/GSDMD signal pathway

10.1016/j.brainresbull.2024.111132 · 2025 · External reference

Supplementation with stigma maydis polysaccharide attenuates autism‐like behaviors and improves gut function in valproic acid‐induced autism model male rats

10.1002/jdn.10354 · 2024 · External reference

A critical period for paired-housing-dependent autistic-like behaviors attenuation in a prenatal valproic acid-induced male mouse model of autism

10.3389/fnins.2024.1467047 · 2025 · External reference

KCNH5 deletion increases autism susceptibility by regulating neuronal growth through Akt/mTOR signaling pathway

10.1016/j.bbr.2024.115069 · 2024 · External reference

Acetyl-l-carnitine alleviates valproate-induced autism-like behaviors through attenuation of hippocampal mitochondrial dysregulation

10.1016/j.neuroscience.2024.08.022 · 2024 · External reference

Three decades of valproate: a current model for studying autism spectrum disorder

10.2174/1570159x22666231003121513 · 2024 · External reference

Mechanistic insights into retinoic-acid treatment for autism in the improvement of social behavior: evidence from a multi omics study in rats

10.1016/j.neuropharm.2024.110244 · 2025 · External reference

Memantine/aripiprazole combination alleviates cognitive dysfunction in valproic acid rat model of autism: hippocampal CREB/BDNF signaling and glutamate homeostasis

10.1007/s13311-023-01360-w · 2023 · External reference