Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Privacy-aware community infrastructureResearch graph
References from Spaceflight-guided pharmacogenomics: a foundational analysis of pharmaceuticals and their responsive gene targets in the space environment. Local targets link to admitted publications; unresolved targets remain external evidence.
The blood-brain barrier in space: Implications for space travelers and for human health on earth
10.3389/fddev.2022.931221 · 2022 · External reference
Optimization of the mevalonate-based isoprenoid biosynthetic pathway in Escherichia coli for production of the anti-malarial drug precursor amorpha-4,11-diene
10.1016/j.ymben.2008.07.007 · 2009 · External reference
Recent trends in advanced oxidation process-based degradation of erythromycin: Pollution status, eco-toxicity and degradation mechanism in aquatic ecosystems
10.1016/j.scitotenv.2021.145389 · 2021 · External reference
A retrospective study of promethazine and its failure to produce the expected incidence of sedation during space flight
10.1002/j.1552-4604.1994.tb02019.x · 1994 · External reference
A pharmacogenetics study of the human glucuronosyltransferase UGT1A4
10.1097/fpc.0b013e3283331637 · 2009 · External reference
NASA GeneLab: Interfaces for the exploration of space omics data
10.1093/nar/gkaa887 · 2021 · External reference
Unresolved reference
External reference
Supplying a pharmacy for NASA exploration spaceflight: Challenges and current understanding
10.1038/s41526-019-0075-2 · 2019 · External reference
Mevalonate pathway: A review of clinical and therapeutical implications
10.1016/j.clinbiochem.2007.03.016 · 2007 · External reference
Dgidb 5.0: Rebuilding the drug–gene interaction database for precision medicine and drug discovery platforms
10.1093/nar/gkad1040 · 2023 · External reference
Nanopore DNA sequencing and genome assembly on the International Space Station
10.1038/s41598-017-18364-0 · 2017 · External reference
Targeting of mevalonateisoprenoid pathway in acute myeloid leukemia cells by bisphosphonate drugs
10.3390/biomedicines10051146 · 2022 · External reference
Stability of vitamin B complex in multivitamin and multimineral supplement tablets after space flight
10.1016/j.jpba.2011.03.030 · 2011 · External reference
Immune system dysregulation during spaceflight: Potential countermeasures for deep space exploration missions
10.3389/fimmu.2018.01437 · 2018 · External reference
Comparison of treatment strategies for space motion sickness
10.1016/0094-5765(93)90074-7 · 1993 · External reference
Evaluation of physical and chemical changes in pharmaceuticals flown on space missions
10.1208/s12248-011-9270-0 · 2011 · External reference
Critical review of preclinical approaches to investigate cytochrome p450-mediated therapeutic protein drug-drug interactions and recommendations for best practices: A white paper
10.1124/dmd.113.052225 · 2013 · External reference
Influence of trace erythromycin and erythromycin-H2O on carbon and nutrients removal and on resistance selection in sequencing batch reactors (SBRs)
10.1007/s00253-009-2201-7 · 2009 · External reference
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight
10.1126/science.aau8650 · 2019 · External reference
Fanconi syndrome (adult type) developing secondary to the ingestion of outdated tetracycline
10.7326/0003-4819-58-3-523 · 1963 · External reference
Toxicity of tetracyclines and tetracycline degradation products to environmentally relevant bacteria, including selected tetracycline-resistant bacteria
10.1007/s00244-001-0017-2 · 2002 · External reference
Exposure to formaldehyde and its potential human health hazards
10.1080/10590501.2011.629972 · 2011 · External reference
Impact of visceral leishmaniasis and curative chemotherapy on cytochrome P450 activity in Brazilian patients
10.1111/bcp.12677 · 2015 · External reference
In vitro induction of resistance to erythromycin by its metabolite
10.1128/aac.19.4.628 · 1981 · External reference
Multiobjective optimization approach in evaluation of chromatographic behaviour of zolpidem tartrate and its degradation products
10.1007/s10337-011-2064-9 · 2011 · External reference
Stress degradation studies on zolpidem tartrate using LC-DAD and LC-MS methods
10.1556/achrom.26.2014.1.8 · 2014 · External reference
Hydroquinone: An evaluation of the human risks from its carcinogenic and mutagenic properties
10.1080/10408440701638970 · 2007 · External reference
Nanopore sequencing in microgravity
10.1038/npjmgrav.2016.35 · 2016 · External reference
Impact of space environment on stability of medicines: Challenges and prospects
10.1016/j.jpba.2016.12.040 · 2017 · External reference
Hepatic function in rats after spaceflight: effects on lipids, glycogen, and enzymes
10.1152/ajpregu.1987.252.2.r222 · 1987 · External reference
Lactic acidosis and Fanconi's syndrome due to degraded tetracycline
10.1136/bmj.283.6306.1576-a · 1981 · External reference
Investigation of spaceflight induced changes to astronaut microbiomes
10.3389/fmicb.2021.659179 · 2021 · External reference
Effect of the CYP3A4 inhibitor erythromycin on the pharmacokinetics of lignocaine and its pharmacologically active metabolites in subjects with normal and impaired liver function
10.1046/j.1365-2125.2003.01718.x · 2003 · External reference
The future of personalized medicine in space: From observations to countermeasures
10.3389/fbioe.2021.739747 · 2021 · External reference
Pharmacokinetic consequences of spaceflight
10.1111/j.1749-6632.1991.tb27292.x · 1991 · External reference
A review on the degradation of acetaminophen by advanced oxidation process: pathway, by-products, biotoxicity, and density functional theory calculation
10.1039/d2ra02469a · 2022 · External reference
The effect of long-term spaceflight on drug potency and the risk of medication failure
10.1038/s41526-023-00271-6 · 2023 · External reference
Formaldehyde metabolism and its impact on human health
10.1016/j.cotox.2018.07.001 · 2018 · External reference
Personalized medicine in human space flight: Using omics based analyses to develop individualized countermeasures that enhance astronaut safety and performance
10.1007/s11306-013-0556-3 · 2013 · External reference
Systemic elevation of gut derived p-cresol during one year in space: Implications for brain, heart, bone, liver, and microbiome in astronauts Special Issue: Bioconvergence: A New Frontier for Understanding and Enhancing Human Adaptations to Extreme Environments (in press)
2026 · External reference
Pharmacogenomics in spaceflight
10.1007/978-3-319-50909-9_26-1 · 2019 · External reference
Precision medicine in human spaceflight: Applying systems thinking to principles, concepts, and methods of assessment
2025 · External reference
Hydroquinone
2023 · External reference
Advancing the integration of biosciences data sharing to further enable space exploration
10.1016/j.celrep.2020.108441 · 2020 · External reference
Tetracycline
2023 · External reference
Validated stability indicating HPLC method for determination of zolpidem in the presence of its degradation products
10.2174/2210289201203010013 · 2012 · External reference
The transcriptome response of astronaut leukocytes to long missions aboard the International Space Station reveals immune modulation
10.3389/fimmu.2023.1171103 · 2023 · External reference
Factors affecting drug bioavailability in space
10.1002/j.1552-4604.1994.tb02022.x · 1994 · External reference
Chapter 4 pharmacology in space: pharmacotherapy
1997 · External reference
Oxidative degradation of pharmaceutically important phenothiazines I: Isolation and identification of oxidation products of promethazine
10.1002/jps.2600670826 · 1978 · External reference
Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3: Metabolite structure, kinetics, inducibility, and interindividual variability
10.1210/en.2013-2013 · 2014 · External reference
Hydroquinone and its analogues in dermatology – a potential health risk
10.1111/j.1473-2165.2005.40202.x · 2005 · External reference
The FAIR Guiding Principles for scientific data management and stewardship
10.1038/sdata.2016.18 · 2016 · External reference
Effects of spaceflight on human induced pluripotent stem cell-derived cardiomyocyte structure and function
10.1016/j.stemcr.2019.10.006 · 2019 · External reference
Medication use by U.S. crewmembers on the International Space Station
10.1096/fj.14-264838 · 2015 · External reference
Chemical Potency and Degradation Products of Medications Stored Over 550 Earth Days at the International Space Station
10.1208/s12248-015-9834-5 · 2016 · External reference
Effect of CYP3A4 metabolism on sex differences in the pharmacokinetics and pharmacodynamics of zolpidem
10.1038/s41598-021-98689-z · 2021 · External reference
