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References from From reference epigenomes to response epigenomes: a public-health case built on the developing brain. Local targets link to admitted publications; unresolved targets remain external evidence.
Integrative analysis of 111 reference human epigenomes
10.1038/nature14248 · 2015 · External reference
Expanded encyclopaedias of DNA elements in the human and mouse genomes
2020 · External reference
The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery
10.1016/j.cell.2016.11.007 · 2016 · External reference
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
10.1038/ng1089 · 2003 · External reference
The epigenomic interface between genome and environment in common complex diseases
10.1093/bfgp/elq026 · 2010 · External reference
Complementing the genome with an “exposome”: the outstanding challenge of environmental exposure measurement in molecular epidemiology
10.1158/1055-9965.epi-05-0456 · 2005 · External reference
The exposome: from concept to utility
10.1093/ije/dyr236 · 2012 · External reference
The nature of nurture: refining the definition of the exposome
10.1093/toxsci/kft251 · 2014 · External reference
Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis
10.1289/ehp.1509912 · 2016 · External reference
Prevalence and early identification of autism spectrum disorder among children aged 4 and 8 years — Autism and Developmental Disabilities Monitoring Network, 16 sites, United States, 2022
10.15585/mmwr.ss7402a1 · 2025 · External reference
Revolutionizing developmental neurotoxicity testing—a journey from animal models to advanced in vitro systems
10.14573/altex.2403281 · 2024 · External reference
NAMazing: MAHA finally names alternatives to animal testing the path to find causes of autism - now make the banner meet the bench
10.1016/j.namjnl.2025.100053 · 2025 · External reference
Persistent epigenetic differences associated with prenatal exposure to famine in humans
10.1073/pnas.0806560105 · 2008 · External reference
DNA methylation in newborns and maternal smoking in pregnancy: genome-wide consortium meta-analysis
10.1016/j.ajhg.2016.02.019 · 2016 · External reference
Gene– environment interactions in developmental neurotoxicity: a case study of synergy between chlorpyrifos and CHD8 knockout in human BrainSpheres
10.1289/ehp8580 · 2021 · External reference
The exposome from neurodevelopment to neurodegeneration: a narrative review
10.1016/j.neubiorev.2025.106247 · 2025 · External reference
An integrated approach to understanding the effects of exposome on neuroplasticity
10.1016/j.bbr.2025.115516 · 2025 · External reference
An interdisciplinary fetal neonatal neurology collaborative promotes integrative life-course brain health
10.3389/fneur.2025.1725289 · 2026 · External reference
Matrescence: lifetime impact of motherhood on cognition and the brain
2023 · External reference
Cohort profile: pregnancy and childhood epigenetics (PACE) consortium
10.1093/ije/dyx190 · 2018 · External reference
Human early life Exposome (HELIX) study: a European population-based exposome cohort
10.1136/bmjopen-2017-021311 · 2018 · External reference
Multiomics signatures of the human early life exposome
10.1038/s41467-022-34422-2 · 2022 · External reference
The NIEHS TaRGET II Consortium and environmental epigenomics
10.1038/nbt.4099 · 2018 · External reference
Genetics and environment distinctively shape the human immune cell epigenome
10.1038/s41588-025-02479-6 · 2026 · External reference
Rationale and study protocol of the MAMELI cohort study (mapping the methylation of repetitive elements to track the Exposome effects on health: the city of Legnano as a living lab)
10.1371/journal.pone.0326467 · 2025 · External reference
Oligodendrogenesis and myelination tracing in a CRISPR/Cas9-engineered brain microphysiological system
10.3389/fncel.2022.1094291 · 2023 · External reference
The future of 3D brain cultures in developmental neurotoxicity testing
10.3389/ftox.2022.808620 · 2022 · External reference
The promise and potential of brain organoids
10.1002/adhm.202302745 · 2024 · External reference
Organoid intelligence for developmental neurotoxicity testing
10.3389/fncel.2024.1480845 · 2024 · External reference
Towards learning and memory risk assessment with human neural organoids: barriers and opportunities
10.3389/ftox.2026.1783893 · 2026 · External reference
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
10.1038/nbt.3199 · 2015 · External reference
Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease
10.1093/ije/dyr233 · 2012 · External reference
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
10.1038/s41588-021-00923-x · 2021 · External reference
Causality analysis of toxicological mechanisms in networked systems such as adverse outcome pathway networks
10.1007/s00204-026-04386-z · 2026 · External reference
Meeting-in-the-middle using metabolic profiling—a strategy for the identification of intermediate biomarkers in cohort studies
10.3109/1354750x.2010.533285 · 2011 · External reference
DNA methylation age of human tissues and cell types
10.1186/gb-2013-14-10-r115 · 2013 · External reference
DNA methylation GrimAge strongly predicts lifespan and healthspan
10.18632/aging.101684 · 2019 · External reference
DunedinPACE, a DNA methylation biomarker of the pace of aging
10.7554/elife.73420 · 2022 · External reference
Cognitive sovereignty and decolonial public health: reclaiming epistemic authority in the global AI era
10.3389/fpubh.2026.1785170 · 2026 · External reference
Intersectionality and why it matters to global health
10.1016/s0140-6736(18)31431-4 · 2018 · External reference
Transdisciplinary fetal-neonatal neurology training integrates women's and children's health with life-course brain capital strategies: a narrative review
10.3389/fneur.2026.1756627 · 2026 · External reference
Judgment under uncertainty: heuristics and biases
10.1126/science.185.4157.1124 · 1974 · External reference
Neuroecological links of the exposome and one health
10.1016/j.neuron.2024.04.016 · 2024 · External reference
The promise and potential of brain organoids
10.1002/adhm.202302745 · ExternalCitation · doi-reference
Causality analysis of toxicological mechanisms in networked systems such as adverse outcome pathway networks
10.1007/s00204-026-04386-z · ExternalCitation · doi-reference
DNA methylation in newborns and maternal smoking in pregnancy: genome-wide consortium meta-analysis
10.1016/j.ajhg.2016.02.019 · ExternalCitation · doi-reference
An integrated approach to understanding the effects of exposome on neuroplasticity
10.1016/j.bbr.2025.115516 · ExternalCitation · doi-reference
The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery
10.1016/j.cell.2016.11.007 · ExternalCitation · doi-reference
NAMazing: MAHA finally names alternatives to animal testing the path to find causes of autism - now make the banner meet the bench
10.1016/j.namjnl.2025.100053 · ExternalCitation · doi-reference
The exposome from neurodevelopment to neurodegeneration: a narrative review
10.1016/j.neubiorev.2025.106247 · ExternalCitation · doi-reference
Neuroecological links of the exposome and one health
10.1016/j.neuron.2024.04.016 · ExternalCitation · doi-reference
Intersectionality and why it matters to global health
10.1016/s0140-6736(18)31431-4 · ExternalCitation · doi-reference
Integrative analysis of 111 reference human epigenomes
10.1038/nature14248 · ExternalCitation · doi-reference
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
10.1038/nbt.3199 · ExternalCitation · doi-reference
The NIEHS TaRGET II Consortium and environmental epigenomics
10.1038/nbt.4099 · ExternalCitation · doi-reference
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
10.1038/ng1089 · ExternalCitation · doi-reference
Multiomics signatures of the human early life exposome
10.1038/s41467-022-34422-2 · ExternalCitation · doi-reference
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
10.1038/s41588-021-00923-x · ExternalCitation · doi-reference
Genetics and environment distinctively shape the human immune cell epigenome
10.1038/s41588-025-02479-6 · ExternalCitation · doi-reference
Persistent epigenetic differences associated with prenatal exposure to famine in humans
10.1073/pnas.0806560105 · ExternalCitation · doi-reference
The epigenomic interface between genome and environment in common complex diseases
10.1093/bfgp/elq026 · ExternalCitation · doi-reference
Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease
10.1093/ije/dyr233 · ExternalCitation · doi-reference
The exposome: from concept to utility
10.1093/ije/dyr236 · ExternalCitation · doi-reference
Cohort profile: pregnancy and childhood epigenetics (PACE) consortium
10.1093/ije/dyx190 · ExternalCitation · doi-reference
The nature of nurture: refining the definition of the exposome
10.1093/toxsci/kft251 · ExternalCitation · doi-reference
Judgment under uncertainty: heuristics and biases
10.1126/science.185.4157.1124 · ExternalCitation · doi-reference
Human early life Exposome (HELIX) study: a European population-based exposome cohort
10.1136/bmjopen-2017-021311 · ExternalCitation · doi-reference
Complementing the genome with an “exposome”: the outstanding challenge of environmental exposure measurement in molecular epidemiology
10.1158/1055-9965.epi-05-0456 · ExternalCitation · doi-reference
DNA methylation age of human tissues and cell types
10.1186/gb-2013-14-10-r115 · ExternalCitation · doi-reference
Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis
10.1289/ehp.1509912 · ExternalCitation · doi-reference
Gene– environment interactions in developmental neurotoxicity: a case study of synergy between chlorpyrifos and CHD8 knockout in human BrainSpheres
10.1289/ehp8580 · ExternalCitation · doi-reference
Rationale and study protocol of the MAMELI cohort study (mapping the methylation of repetitive elements to track the Exposome effects on health: the city of Legnano as a living lab)
10.1371/journal.pone.0326467 · ExternalCitation · doi-reference
Revolutionizing developmental neurotoxicity testing—a journey from animal models to advanced in vitro systems
10.14573/altex.2403281 · ExternalCitation · doi-reference
Prevalence and early identification of autism spectrum disorder among children aged 4 and 8 years — Autism and Developmental Disabilities Monitoring Network, 16 sites, United States, 2022
10.15585/mmwr.ss7402a1 · ExternalCitation · doi-reference
DNA methylation GrimAge strongly predicts lifespan and healthspan
10.18632/aging.101684 · ExternalCitation · doi-reference
Meeting-in-the-middle using metabolic profiling—a strategy for the identification of intermediate biomarkers in cohort studies
10.3109/1354750x.2010.533285 · ExternalCitation · doi-reference
Oligodendrogenesis and myelination tracing in a CRISPR/Cas9-engineered brain microphysiological system
10.3389/fncel.2022.1094291 · ExternalCitation · doi-reference
Organoid intelligence for developmental neurotoxicity testing
10.3389/fncel.2024.1480845 · ExternalCitation · doi-reference
An interdisciplinary fetal neonatal neurology collaborative promotes integrative life-course brain health
10.3389/fneur.2025.1725289 · ExternalCitation · doi-reference
Transdisciplinary fetal-neonatal neurology training integrates women's and children's health with life-course brain capital strategies: a narrative review
10.3389/fneur.2026.1756627 · ExternalCitation · doi-reference
Cognitive sovereignty and decolonial public health: reclaiming epistemic authority in the global AI era
10.3389/fpubh.2026.1785170 · ExternalCitation · doi-reference
The future of 3D brain cultures in developmental neurotoxicity testing
10.3389/ftox.2022.808620 · ExternalCitation · doi-reference
Towards learning and memory risk assessment with human neural organoids: barriers and opportunities
10.3389/ftox.2026.1783893 · ExternalCitation · doi-reference
DunedinPACE, a DNA methylation biomarker of the pace of aging
10.7554/elife.73420 · ExternalCitation · doi-reference