Research graph
References from Myosteatosis: an emerging biomarker of aging. Local targets link to admitted publications; unresolved targets remain external evidence.
Skeletal muscle adiposity is a novel risk factor for poor cognition in African Caribbean women
10.1002/oby.23816 · 2023 · External reference
Skeletal muscle adiposity and cognitive decline in a biracial cohort: insights from coronary artery risk development in young adults (CARDIA) study
10.1002/alz.70846 · 2025 · External reference
Intramuscular fat and inflammation differ in older adults: the impact of frailty and inactivity
10.1007/s12603-014-0019-1 · External reference
Intermuscular fat: a review of the consequences and causes
10.1155/2014/309570 · External reference
Hip but not thigh intramuscular adipose tissue is associated with poor balance and increased temporal gait variability in older adults
10.2174/1874609807666140706150924 · External reference
The effects of diet on the proportion of intramuscular fat in human muscle: a systematic review and meta-analysis
10.3389/fnut.2018.00007 · 2018 · External reference
Updated systematic review and meta-analysis on diagnostic issues and the prognostic impact of myosteatosis: a new paradigm beyond sarcopenia
10.1016/j.arr.2021.101398 · 2021 · External reference
Ethnic differences in adipose tissue dysfunction and insulin resistance: a scoping review
10.1016/j.diabres.2025.112363 · 2025 · External reference
Skeletal muscle characteristics in sedentary Black and Caucasian males
10.1152/jappl.1986.61.5.1758 · 1986 · External reference
Variations of CT-based trunk muscle attenuation by age, sex, and specific muscle
10.1093/gerona/gls168 · 2013 · External reference
What is normal age-related thigh muscle composition among 45- to 84-year-old adults from the UK biobank study
10.1007/s11357-024-01304-y · 2025 · External reference
Measurement of skeletal muscle radiation attenuation and basis of its biological variation
10.1111/apha.12224 · 2014 · External reference
Longitudinal changes in intermuscular fat volume and quadriceps muscle volume in the thighs of women with knee osteoarthritis
10.1002/acr.20628 · 2012 · External reference
Myostatin antibody (LY2495655) in older weak fallers: a proof-of-concept, randomised, phase 2 trial
10.1016/s2213-8587(15)00298-3 · 2015 · External reference
Mitochondria and ageing: role in heart, skeletal muscle and adipose tissue
10.1002/jcsm.12178 · 2017 · External reference
Unresolved reference
2023 · External reference
Origins of metabolic complications in obesity: ectopic fat accumulation. The importance of the qualitative aspect of lipotoxicity
10.1097/mco.0b013e32834ad966 · 2011 · External reference
Role of leptin resistance in the development of obesity in older patients
10.2147/cia.s36367 · 2013 · External reference
Black and white race differences in aerobic capacity, muscle fiber type, and their influence on metabolic processes
10.1007/s40279-015-0318-7 · 2015 · External reference
Skeletal muscle size, function, and adiposity with lifelong aerobic exercise
10.1152/japplphysiol.00426.2019 · 2020 · External reference
Adipose tissue depot volume relationships with spinal trabecular bone mineral density in African Americans with diabetes
10.1371/journal.pone.0191674 · 2018 · External reference
Prevalence of diabetes by race and ethnicity in the United States, 2011-2016
10.1001/jama.2019.19365 · 2019 · External reference
Age-related testosterone decline: mechanisms and intervention strategies
10.1186/s12958-024-01316-5 · 2024 · External reference
Underexplored terrain: effects of high priority environmental toxicants on skeletal muscle
10.1080/10937404.2025.2593824 · 2026 · External reference
Serum immunoreactive-leptin concentrations in normal-weight and Obese humans
10.1056/nejm199602013340503 · 1996 · External reference
Role of estrogens in adipocyte development and function
10.1177/153537020422901107 · 2004 · External reference
The need for standardized assessment of muscle quality in skeletal muscle function deficit and other aging-related muscle dysfunctions: a symposium report
10.3389/fphys.2017.00087 · 2017 · External reference
Myosteatosis in the context of skeletal muscle function deficit: an interdisciplinary workshop at the national institute on aging
10.3389/fphys.2020.00963 · 2020 · External reference
Defining reference values for body composition indices by magnetic resonance imaging in UK biobank
10.1002/jcsm.13181 · 2023 · External reference
Longitudinal study of muscle strength, quality, and adipose tissue infiltration
10.3945/ajcn.2009.28047 · 2009 · External reference
Unveiling inequalities: racial, ethnic, and socioeconomic disparities in diabetes: findings from the 2007-2020 NHANES data among U.S. adults
10.1016/j.pmedr.2024.102957 · 2025 · External reference
The effects of myosteatosis on skeletal muscle function in older adults
10.14814/phy2.16042 · 2024 · External reference
The pathophysiology and treatment of osteoporosis
10.1016/j.clinthera.2015.06.006 · 2015 · External reference
Thigh fat and muscle each contribute to excess cardiometabolic risk in south Asians, independent of visceral adipose tissue
10.1002/oby.20796 · 2014 · External reference
The influence of estrogen on skeletal muscle: sex matters
10.2165/11319760-000000000-00000 · 2010 · External reference
Computed tomography-based skeletal muscle and adipose tissue attenuation: variations by age, sex, and muscle
10.1016/j.exger.2021.111306 · 2021 · External reference
Leptin's physiologic role: does the emperor of energy balance have no clothes?
10.1016/j.cmet.2017.05.013 · 2017 · External reference
Fibro-adipogenic progenitors in physiological adipogenesis and intermuscular adipose tissue remodeling
10.1016/j.mam.2024.101277 · 2024 · External reference
Leptin receptor 170 kDa (OB-R170) protein expression is reduced in Obese human skeletal muscle: a potential mechanism of leptin resistance
10.1113/expphysiol.2009.049270 · 2010 · External reference
Adipose tissue in muscle: a novel depot similar in size to visceral adipose tissue
10.1093/ajcn/81.4.903 · 2005 · External reference
The release of adipose stromal cells from subcutaneous adipose tissue regulates ectopic intramuscular adipocyte deposition
10.1016/j.celrep.2019.03.038 · 2019 · External reference
Attenuation of skeletal muscle and strength in the elderly: the health ABC study
10.1152/jappl.2001.90.6.2157 · 2001 · External reference
The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study
10.1093/gerona/61.10.1059 · 2006 · External reference
Effects of physical activity on strength and skeletal muscle fat infiltration in older adults: a randomized controlled trial
10.1152/japplphysiol.90425.2008 · 2008 · External reference
Intermuscular adipose tissue in metabolic disease
10.1038/s41574-022-00784-2 · 2023 · External reference
Leptin signaling in skeletal muscle after bed rest in healthy humans
10.1007/s00421-013-2779-4 · 2014 · External reference
Reduced mitochondrial lipid oxidation leads to fat accumulation in myosteatosis
10.1096/fj.201802457rr · 2019 · External reference
Myokines and interorgan crosstalk: bridging exercise to health promotion and disease prevention
10.6065/apem.2448218.109 · 2025 · External reference
Change in D3Cr muscle mass in oldest old men and its association with changes in grip strength and walking speed
10.1371/journal.pone.0320752 · 2025 · External reference
Network-based systematic dissection of exercise-induced inhibition of myosteatosis in older individuals
10.1113/jp285349 · 2025 · External reference
Gluteal muscle composition differentiates fallers from non-fallers in community dwelling older adults
10.1186/1471-2318-14-37 · 2014 · External reference
Leptin and aging: correlation with endocrine changes in Male and female healthy adult populations of different body weights
10.1210/jcem.85.5.6572 · 2000 · External reference
Sex differences in human skeletal muscle fiber types and the influence of age, physical activity, and muscle group: a systematic review and meta-analysis
10.14814/phy2.70616 · 2025 · External reference
Mitochondrial phenotype as a driver of the racial dichotomy in obesity and insulin resistance
10.3390/biomedicines10061456 · 2022 · External reference
Population-based study of age- and sex-related differences in muscle density and size in thoracic and lumbar spine: the framingham study
10.1007/s00198-018-4490-0 · 2018 · External reference
Cellular senescence biomarker p16INK4a+ cell burden in thigh adipose is associated with poor physical function in older women
10.1093/gerona/glx134 · 2018 · External reference
Prevalence and trends in physical activity among older adults in the United States: a comparison across three national surveys
10.1016/j.ypmed.2016.05.009 · 2016 · External reference
Animal models of steatosis
10.1055/s-2001-12932 · 2001 · External reference
Muscle area and density and risk of all-cause mortality: the multi-ethnic study of atherosclerosis
10.1016/j.metabol.2020.154321 · 2020 · External reference
Axonal degeneration affects muscle density in older men and women
10.1016/j.neurobiolaging.2005.06.009 · 2006 · External reference
Relationship of intramyocellular lipid to insulin sensitivity May differ with ethnicity in healthy girls and women
10.1038/oby.2010.148 · 2011 · External reference
Physical exercise-induced myokines and muscle-adipose tissue crosstalk: a review of current knowledge and the implications for health and metabolic diseases
10.3389/fphys.2018.01307 · 2018 · External reference
Role of myokines in regulating skeletal muscle mass and function
10.3389/fphys.2019.00042 · 2019 · External reference
Interethnic differences in muscle, liver and abdominal fat partitioning in Obese adolescents
10.1371/journal.pone.0000569 · 2007 · External reference
Impact of abdominal visceral and subcutaneous adipose tissue on cardiometabolic risk factors: the Jackson heart study
10.1210/jc.2010-1378 · 2010 · External reference
Trends in diet quality among older US adults from 2001 to 2018
10.1001/jamanetworkopen.2022.1880 · 2022 · External reference
Age and gender related effects on adipose tissue compartments of subjects with increased risk for type 2 diabetes: a whole body MRI/MRS study
10.1007/s10334-005-0104-x · 2005 · External reference
Adiposity, fat patterning, and the metabolic syndrome among diverse youth: the EPOCH study
10.1016/j.jpeds.2012.05.003 · 2012 · External reference
Skeletal muscle fat infiltration: impact of age, inactivity, and exercise
10.1007/s12603-010-0081-2 · 2010 · External reference
Abdominal myosteatosis is associated with lower processing speed in a multiethnic cohort of older adults
10.1016/j.archger.2025.105823 · 2025 · External reference
Determinants of intramyocellular lipid accumulation in early childhood
10.1038/s41366-019-0435-8 · 2020 · External reference
Greater adipose tissue infiltration in skeletal muscle among older men of African ancestry
10.1210/jc.2008-2541 · External reference
Association of the CPT1B gene with skeletal muscle fat infiltration in Afro-Caribbean men
10.1038/oby.2008.677 · External reference
Markers of inflammation are heritable and associated with subcutaneous and ectopic skeletal muscle adiposity in African ancestry families
10.1089/met.2010.0133 · 2011 · External reference
Abdominal myosteatosis is independently associated with hyperinsulinemia and insulin resistance among older men without diabetes
10.1002/oby.20346 · 2013 · External reference
Greater skeletal muscle fat infiltration is associated with higher all-cause and cardiovascular mortality in older men
10.1093/gerona/glv027 · 2015 · External reference
Myosteatosis increases with aging and is associated with incident diabetes in African ancestry men
10.1002/oby.21328 · 2016 · External reference
Computed tomography-derived myosteatosis and metabolic disorders
10.4093/dmj.2020.0277 · 2021 · External reference
Adipose tissue infiltration in skeletal muscle: age patterns and association with diabetes among men of African ancestry
10.1093/ajcn/87.6.1590 · External reference
Sex and genetic effects on upper and lower body fat and associations with diabetes in multigenerational families of African heritage
10.1016/j.metabol.2008.01.022 · External reference
Insulin sensitivity and skeletal muscle mitochondrial respiration in black and white women with obesity
10.1210/clinem/dgae600 · 2025 · External reference
Narrative review of sex differences in muscle strength, endurance, activation, size, fiber type, and strength training participation rates, preferences, motivations, injuries, and neuromuscular adaptations
10.1519/jsc.0000000000004329 · 2023 · External reference
Thigh and abdominal adipose tissue depot associations with testosterone levels in postmenopausal females
10.1111/cen.13921 · 2019 · External reference
CT muscle density, D3Cr muscle mass, and body fat associations with physical performance, mobility outcomes, and mortality risk in older men
10.1093/gerona/glab266 · 2022 · External reference
The altered fate of aging satellite cells is determined by signaling and epigenetic changes
10.3389/fgene.2015.00059 · 2015 · External reference
Role of fibro-adipogenic progenitor cells in muscle atrophy and musculoskeletal diseases
10.1016/j.coph.2021.03.003 · 2021 · External reference
Effects of exercise with or without a hypocaloric diet on intermuscular and intramuscular fat: a systematic review
10.1007/s40520-025-03097-2 · 2025 · External reference
Effect of exercise on myosteatosis in adults: a systematic review and meta-analysis
10.1152/japplphysiol.00738.2020 · 2021 · External reference
Muscle quality and myosteatosis: novel associations with mortality risk: the age, gene/environment susceptibility (AGES)-reykjavik study
10.1093/aje/kwv153 · 2016 · External reference
Age-related change in skeletal muscle strength, size, and adiposity over 18 years in Caribbean men
10.1007/s11357-025-02023-8 · 2025 · External reference
Intermuscular adipose tissue directly modulates skeletal muscle insulin sensitivity in humans
10.1152/ajpendo.00243.2018 · 2019 · External reference
Impact of weight loss on physical function with changes in strength, muscle mass, and muscle fat infiltration in overweight to moderately Obese older adults: a randomized clinical trial
10.1155/2011/516576 · 2011 · External reference
Body composition remodeling and mortality: the health aging and body composition study
10.1093/gerona/glw163 · 2017 · External reference
Body composition remodeling and incident mobility limitations in African ancestry men
10.1093/gerona/gly067 · 2019 · External reference
Thigh and calf myosteatosis are strongly associated with muscle and physical function in African Caribbean men
10.1093/gerona/glac124 · 2023 · External reference
Less favorable body composition and adipokines in south Asians compared with other US ethnic groups: results from the MASALA and MESA studies
10.1038/ijo.2015.219 · 2016 · External reference
Abdominal body composition measured by quantitative computed tomography and risk of non-spine fractures: the osteoporotic fractures in men (MrOS) study
10.1007/s00198-013-2322-9 · 2013 · External reference
Ethnicity-related skeletal muscle differences across the lifespan
10.1002/ajhb.20956 · 2010 · External reference
Alterations in muscle attenuation following detraining and retraining in resistance-trained older adults
10.1159/000182084 · 2009 · External reference
Relationships of BMI to cardiovascular risk factors differ by ethnicity
10.1038/oby.2009.407 · 2010 · External reference
Ectopic fat distribution and adverse muscle composition in south Asians: findings from the UK biobank
10.1016/j.ajpc.2025.101284 · 2025 · External reference
Imaging in patients with obesity: challenges, applications and future directions
10.1038/s41574-025-01166-0 · 2025 · External reference
Unresolved reference
2024 · External reference
Sex-specific differences in lipid and glucose metabolism
10.3389/fendo.2014.00241 · 2014 · External reference
The mitochondrial puzzle: why obesity affects insulin sensitivity differently in black and white women
10.1210/clinem/dgae686 · 2025 · External reference
Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons
10.1093/gerona/60.3.324 · 2005 · External reference
Reasons for intentional weight loss, unintentional weight loss, and mortality in older men
10.1001/archinte.165.9.1035 · 2005 · External reference
Trajectories of gait speed predict mortality in well-functioning older adults: the health, aging and body composition study
10.1093/gerona/gls197 · 2013 · External reference
Proton magnetic resonance spectroscopy shows lower intramyocellular lipid accumulation in middle-aged subjects predisposed to familial longevity
10.1152/ajpendo.00455.2011 · 2012 · External reference
Dose-dependent effects of testosterone on regional adipose tissue distribution in healthy young men
10.1210/jc.2003-031492 · 2004 · External reference
Reference values for paravertebral muscle size and myosteatosis in Chinese adults, a nationwide multicenter study
10.1016/j.acra.2024.02.005 · 2024 · External reference
The important role of fatty infiltration of skeletal muscle in aging: skeletal muscle function, pathological mechanisms, and intervention
10.1152/ajpendo.00473.2025 · 2026 · External reference
Intramuscular adipose tissue and central activation in older adults
10.1002/mus.23506 · 2012 · External reference
Intermuscular adipose tissue in obesity and related disorders: cellular origins, biological characteristics and regulatory mechanisms
10.3389/fendo.2023.1280853 · 2023 · External reference
Myosteatosis: epidemiological insights, functional decline, and diagnostic advances
10.1007/s13679-025-00676-2 · 2025 · External reference
Greater skeletal muscle fat infiltration is associated with higher all-cause mortality among men of African ancestry
10.1093/ageing/afw062 · 2016 · External reference
Myosteatosis and myofibrosis: relationship with aging, inflammation and insulin resistance
10.1016/j.archger.2013.06.001 · 2013 · External reference