Research graph
References from Pollutants regulate changes in pathological markers of neurodegenerative diseases: a new perspective in environmental toxicology. Local targets link to admitted publications; unresolved targets remain external evidence.
Phosphorylation regulates tau’s phase separation behavior and interactions with chromatin
10.1038/s42003-024-05920-4 · 2024 · External reference
Traffic jam at the blood-brain barrier promotes greater accumulation of alzheimer's disease amyloid-β proteins in the cerebral vasculature
10.1021/mp300352c · 2013 · External reference
Lewy body co-pathology in Alzheimer's disease and primary age-related tauopathy contributes to differential neuropathological, cognitive, and brain atrophy patterns
10.1002/alz.14191 · 2025 · External reference
Disruption of large-scale brain systems in advanced aging
10.1016/j.neuron.2007.10.038 · 2007 · External reference
Per- and polyfluoroalkyl substances (PFAS): immunotoxicity at the primary sites of exposure
10.1080/10408444.2025.2501420 · 2025 · External reference
Air pollution in the climate health nexus: a two-decade global review of pollutant trends, health burdens, and monitoring advancements
10.1016/j.pce.2025.104198 · 2025 · External reference
PCB 37 (3,4, 4'-trichlorobiphenyl) increased apoptosis and modulated neuronal morphogenesis in primary rat cortical neuron-glia cocultures in a concentration-sex-age-and CREB-dependent manner
10.1016/j.neuro.2025.08.004 · 2025 · External reference
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
10.1038/nrn2194 · 2007 · External reference
Exosomes as novel regulators of adult neurogenic niches
10.3389/fncel.2015.00501 · 2015 · External reference
Neuropathology of older persons without cognitive impairment from two community-based studies
10.1212/01.wnl.0000219668.47116.e6 · 2006 · External reference
Unveiling the proteomic landscape of extracellular vesicles: implications for neurodegeneration and neuroprotection
10.1111/jnc.70350 · 2026 · External reference
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
10.1038/81834 · 2000 · External reference
Neuroinflammation in Huntington's disease: causes, consequences, and treatment strategies
10.1177/18796397251338207 · 2025 · External reference
Cardiovascular effects of air pollution
10.1016/j.acvd.2017.05.003 · 2017 · External reference
Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry
10.1007/s00401-006-0127-z · 2006 · External reference
Prevalence of cerebral Amyloid Angiopathy and associated risk of subsequent ischemic and hemorrhagic stroke and mortality in a nationwide cohort
10.1002/ana.27253 · 2025 · External reference
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions
10.2353/ajpath.2007.070182 · 2007 · External reference
Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity
10.1038/nrn2214 · 2007 · External reference
The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study
10.1016/s1474-4422(22)00208-3 · 2022 · External reference
Exposure to ambient air pollution and the incidence of dementia: a population-based cohort study
10.1016/j.envint.2017.08.020 · 2017 · External reference
Fused in sarcoma: properties, self-assembly and correlation with neurodegenerative diseases
10.3390/molecules24081622 · 2019 · External reference
Mechanisms of neurotoxicity of organophosphate pesticides and their relation to neurological disorders
10.2147/ndt.s479757 · 2024 · External reference
Amyloid imaging in cognitively normal individuals, at-risk populations and preclinical Alzheimer's disease
10.1016/j.nicl.2013.02.006 · 2013 · External reference
Environmental pollutants as risk factors for neurodegenerative disorders: alzheimer and Parkinson diseases
10.3389/fncel.2015.00124 · 2015 · External reference
Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?
10.1016/j.tips.2009.06.005 · 2009 · External reference
Lifetime consequences of combined maternal lead and stress
10.1111/j.1742-7843.2007.00189.x · 2008 · External reference
Sources of particulate-matter air pollution and its oxidative potential in Europe
10.1038/s41586-020-2902-8 · 2020 · External reference
Cerebrospinal fluid and blood exosomes as biomarkers for amyotrophic lateral sclerosis; a systematic review
10.1186/s13000-024-01473-6 · 2024 · External reference
Developmental exposure to lead (Pb) alters the expression of the human tau gene and its products in a transgenic animal model
10.1016/j.neuro.2016.06.001 · 2016 · External reference
Propagation of tau pathology in a model of early Alzheimer's disease
10.1016/j.neuron.2011.11.033 · 2012 · External reference
18 - mechanisms of bisphenol A toxicity in mitochondria
10.1016/b978-0-323-88462-4.00020-1 · 2023 · External reference
Environmental factors modulating protein conformations and their role in protein aggregation diseases
10.1016/j.tox.2021.153049 · 2022 · External reference
Effects of air pollution on health: a mapping review of systematic reviews and meta-analyses
10.1016/j.envres.2021.111487 · 2021 · External reference
Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria
10.1016/s1474-4422(14)70090-0 · 2014 · External reference
Limbic-predominant age-related TDP-43 encephalopathy: LATE-breaking updates in clinicopathologic features and biomarkers
10.1007/s11910-022-01232-4 · 2022 · External reference
Risk of Alzheimer's disease and environmental bisphenol A exposure
10.1016/j.cotox.2021.03.003 · 2021 · External reference
Calcium and oxidative stress: from cell signaling to cell death
10.1016/s0161-5890(01)00108-0 · 2002 · External reference
Per- and polyfluoroalkyl substances in the environment
10.1126/science.abg9065 · 2022 · External reference
Role of NF-κB in lead exposure-induced activation of astrocytes based on bioinformatics analysis of hippocampal proteomics
10.1016/j.cbi.2022.110310 · 2023 · External reference
Effects of bisphenol A on glucose homeostasis and brain insulin signaling pathways in male mice
10.1016/j.ygcen.2015.01.017 · 2015 · External reference
Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the global burden of disease study 2016
10.1016/s1474-4422(18)30499-x · 2019 · External reference
The Alzheimer's disease exposome
10.1016/j.jalz.2019.06.3914 · 2019 · External reference
Single and repeated bisphenol A treatment induces ROS, Aβ and hyperphosphorylated-tau accumulation, and insulin pathways disruption, through HDAC2 and PTP1B overexpression, leading to SN56 cholinergic apoptotic cell death
10.1016/j.fct.2022.113500 · 2022 · External reference
Air pollution impairs cognition, provokes depressive-like behaviors and alters hippocampal cytokine expression and morphology
10.1038/mp.2011.76 · 2011 · External reference
p62 overexpression induces TDP-43 cytoplasmic mislocalisation, aggregation and cleavage and neuronal death
10.1038/s41598-021-90822-2 · 2021 · External reference
The exposome and human health
10.1021/acs.est.4c13478 · 2025 · External reference
The blood–brain barrier in systemic infection and inflammation
10.1038/s41423-021-00757-x · 2021 · External reference
Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets
10.1038/s41392-023-01588-0 · 2023 · External reference
Cytoplasmic TDP-43 De-mixing independent of stress granules drives inhibition of nuclear import, loss of nuclear TDP-43, and cell death
10.1016/j.neuron.2019.02.038 · 2019 · External reference
Zinc and copper differentially modulate amyloid precursor protein processing by γ-Secretase and Amyloid-β peptide production
10.1074/jbc.m116.754101 · 2017 · External reference
Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits
10.1016/j.nbd.2020.104947 · 2020 · External reference
Association between long-term air pollution, chronic traffic noise, and resting-state functional connectivity in the 1000BRAINS study
10.1289/ehp9737 · 2022 · External reference
The pathophysiology of proximal neurofilamentous giant axonal swellings: implications for the pathogenesis of amyotrophic lateral sclerosis
10.1016/0300-483x(87)90123-5 · 1987 · External reference
Tau PET imaging in neurodegenerative disorders
10.2967/jnumed.121.263196 · 2022 · External reference
Neurofibrillary tangles, amyloid, and memory in aging and mild cognitive impairment
10.1001/archneur.60.5.729 · 2003 · External reference
Exosomes as mediators of neuroinflammation
10.1186/1742-2094-11-68 · 2014 · External reference
Cerebral hypoperfusion and white matter disease in healthy elderly and patients with Alzheimer's disease
10.1111/j.1468-1331.2012.03865.x · 2013 · External reference
The bio-distribution, clearance pathways, and toxicity mechanisms of ambient ultrafine particles
10.1016/j.eehl.2023.06.001 · 2023 · External reference
A scoping review on the characteristics of human exposome studies
10.1007/s40726-019-00130-7 · 2019 · External reference
CSF biomarkers of Alzheimer's disease concord with amyloid-β PET and predict clinical progression: a study of fully automated immunoassays in BioFINDER and ADNI cohorts
10.1016/j.jalz.2018.01.010 · 2018 · External reference
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
10.1126/science.1072994 · 2002 · External reference
Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein
10.1126/scisignal.aau4543 · 2019 · External reference
Exosomes and the prion protein: more than one truth
10.3389/fnins.2017.00194 · 2017 · External reference
Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier
10.1096/fj.08-106997 · 2008 · External reference
Parkinson's disease and pesticides: a toxicological perspective
10.1016/j.tips.2008.03.007 · 2008 · External reference
Inflammasome signalling in brain function and neurodegenerative disease
10.1038/s41583-018-0055-7 · 2018 · External reference
Neuroinflammation in Alzheimer disease
10.1038/s41577-024-01104-7 · 2025 · External reference
Environmental exposure to metals and the development of tauopathies, synucleinopathies, and TDP-43 proteinopathies: a systematic evidence map protocol
10.1016/j.envint.2022.107528 · 2022 · External reference
Systemic inflammation and microglial activation: systematic review of animal experiments
10.1186/s12974-015-0332-6 · 2015 · External reference
Nitration of tau protein is linked to neurodegeneration in tauopathies
10.1016/s0002-9440(10)63462-1 · 2003 · External reference
Silica nanoparticles cause activation of NLRP3 inflammasome in-vitro model-using microglia
10.2147/ijn.s372485 · 2022 · External reference
Association between ambient air pollution and Parkinson's disease: systematic review and meta-analysis
10.1016/j.envres.2018.10.008 · 2019 · External reference
Toward cleaner air and better health: current state, challenges, and priorities
10.1126/science.adp7832 · 2024 · External reference
Smog, sugar, and synapses: unraveling the PM2.5-insulin resistance-alzheimer's disease axis
10.1016/j.redox.2026.104031 · 2026 · External reference
The association between prion proteins and Aβ1-42 oligomers in cytotoxicity and apoptosis
10.1016/j.bbrc.2012.06.056 · 2012 · External reference
Chronic inflammation: a potential target in tauopathies
10.1016/s1474-4422(23)00116-3 · 2023 · External reference
Microglial TLR4-Lyn kinase is a critical regulator of neuroinflammation, Aβ phagocytosis, neuronal damage, and cell survival in Alzheimer’s disease
10.1038/s41598-025-96456-y · 2025 · External reference
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
10.1016/s1474-4422(09)70299-6 · 2010 · External reference
Revised criteria for diagnosis and staging of Alzheimer's disease: alzheimer's association workgroup
10.1002/alz.13859 · 2024 · External reference
Impact of nanoparticles on amyloid peptide and protein aggregation: a review with a focus on gold nanoparticles
10.1039/c8nr04506b · 2018 · External reference
Alternative systems for misfolded protein clearance: life beyond the proteasome
10.1111/febs.15617 · 2021 · External reference
SOD1 and TDP-43 animal models of amyotrophic lateral sclerosis: recent advances in understanding disease toward the development of clinical treatments
10.1007/s00335-011-9339-1 · 2011 · External reference
Air pollution-induced neurotoxicity: the relationship between air pollution, epigenetic changes, and neurological disorders
10.3390/ijms26073402 · 2025 · External reference
Understanding aspects of aluminum exposure in Alzheimer's disease development
10.1111/bpa.12333 · 2016 · External reference
Prevalence and clinical phenotype of quadruple misfolded proteins in older adults
10.1001/jamaneurol.2020.1741 · 2020 · External reference
The amyloid hypothesis in Alzheimer disease: new insights from new therapeutics
10.1038/s41573-022-00391-w · 2022 · External reference
Brain insulin resistance in Alzheimer's disease and related disorders: mechanisms and therapeutic approaches
10.1016/s1474-4422(20)30231-3 · 2020 · External reference
The impact of chemical toxicants and air pollutants on neurodegenerative disorders and their underlying potential mechanisms: a literature review
10.1002/hsr2.72256 · 2026 · External reference
Exposure to quasi-ultrafine particulate matter accelerates memory impairment and Alzheimer's disease-like neuropathology in the AppNL-G-F knock-in mouse model
10.1093/toxsci/kfad036 · 2023 · External reference
Role of cell cycle on the cellular uptake and dilution of nanoparticles in a cell population
10.1038/nnano.2011.191 · 2012 · External reference
A review of airborne polycyclic aromatic hydrocarbons (PAHs) and their human health effects
10.1016/j.envint.2013.07.019 · 2013 · External reference
Persistent organic pollutant-mediated insulin resistance
10.3390/ijerph16030448 · 2019 · External reference
Chronic cerebral hypoperfusion accelerates amyloid beta deposition in APPSwInd transgenic mice
10.1016/j.brainres.2009.07.078 · 2009 · External reference
Microplastics and human health: our great future to think about now
10.1007/s13181-018-0661-9 · 2018 · External reference
Advanced glycation end products-induced Alzheimer's disease and its novel therapeutic approaches: a comprehensive review
10.7759/cureus.61373 · 2024 · External reference
Amyloid-β predominant Alzheimer’s disease neuropathologic change
10.1093/brain/awae325 · 2025 · External reference
Copper, iron, and zinc ions homeostasis and their role in neurodegenerative disorders (metal uptake, transport, distribution and regulation)
10.1016/j.ccr.2009.05.011 · 2009 · External reference
Environmental toxins in neurodegeneration - a narrative review
10.1186/s42466-025-00452-6 · 2025 · External reference
Iron and Alzheimer's disease: an update on emerging mechanisms
10.3233/jad-179944 · 2018 · External reference
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
10.1126/science.6823561 · 1983 · External reference
Studying unconventional secretion of misfolded proteins in cultured cells and primary neurons
10.1007/978-1-0716-2209-4_22 · 2022 · External reference
Neurodegenerative tauopathies
10.1146/annurev.neuro.24.1.1121 · 2001 · External reference
Childhood lead exposure is associated with lower cognitive functioning at older ages
10.1126/sciadv.abn5164 · 2022 · External reference
Particulate matter exposure and neurodegenerative diseases: a comprehensive update on toxicity and mechanisms
10.1016/j.ecoenv.2023.115565 · 2023 · External reference
The prion concept and synthetic prions
10.1016/bs.pmbts.2017.06.002 · 2017 · External reference
Regulating FUS liquid-liquid phase separation via specific metal recognition
10.1007/s10118-022-2763-8 · 2022 · External reference
The mediating function of obesity on endocrine-disrupting chemicals and insulin resistance in children
10.1515/jpem-2022-0354 · 2022 · External reference
Chronic exposure to polystyrene nanoplastics induces intestinal mechanical and immune barrier dysfunction in mice
10.1016/j.ecoenv.2023.115749 · 2024 · External reference
Inhaled pollutants and neurological health via the lung-brain axis
10.1016/j.ecoenv.2025.119091 · 2025 · External reference
Neurotoxic reactive astrocytes are induced by activated microglia
10.1038/nature21029 · 2017 · External reference
Nucleation of protein fibrillation by nanoparticles
10.1073/pnas.0701250104 · 2007 · External reference
Trans-synaptic spread of tau pathology in vivo
10.1371/journal.pone.0031302 · 2012 · External reference
Anionic nanoplastic contaminants promote Parkinson’s disease–associated α-synuclein aggregation
10.1126/sciadv.adi8716 · 2023 · External reference
Acrylamide axonopathy revisited
10.1016/s0041-008x(02)00072-8 · 2003 · External reference
Association between β-Amyloid accumulation and incident dementia in individuals 80 years or older without dementia
10.1212/wnl.0000000000207920 · 2024 · External reference
Formaldehyde induces hyperphosphorylation and polymerization of Tau protein both in vitro and in vivo
10.1016/j.bbagen.2013.04.028 · 2013 · External reference
Long-term air pollution, noise, and structural measures of the default mode network in the brain: results from the 1000BRAINS cohort
10.1016/j.ijheh.2021.113867 · 2022 · External reference
Environmental pollutants and the gut microbiota: mechanistic links from exposure to systemic disease
10.3389/fmicb.2026.1737229 · 2026 · External reference
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
10.1016/0092-8674(93)90585-e · 1993 · External reference
The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein
10.1074/jbc.c100560200 · 2002 · External reference
Particulate matter impairs immune system function by up-regulating inflammatory pathways and decreasing pathogen response gene expression
10.1038/s41598-023-39921-w · 2023 · External reference
Mono(2-ethylhexyl) phthalate disrupts mitochondrial function, dynamics and biogenesis in human trophoblast cells at human exposure range concentrations
10.3390/toxics13090770 · 2025 · External reference
Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution
10.1038/s41586-019-0924-x · 2019 · External reference
Polychlorinated biphenyls induce oxidative stress and metabolic responses in astrocytes
10.1016/j.neuro.2021.07.001 · 2021 · External reference
Diagnosis and management of dementia with lewy bodies: fourth consensus report of the DLB consortium
10.1212/wnl.0000000000004058 · 2017 · External reference
Endogenous alpha-synuclein is essential for the transfer of pathology by exosome-enriched extracellular vesicles, following inoculation with preformed fibrils in vivo
10.14336/ad.2023.0614 · 2024 · External reference
Mechanisms of prion-induced toxicity
10.1007/s00441-022-03683-0 · 2023 · External reference
Methylmercury exposure and health effects in humans: a worldwide concern
10.1579/0044-7447(2007)36[3:meahei]2.0.co;2 · 2007 · External reference
Axonal transport deficits and neurodegenerative diseases
10.1038/nrn3380 · 2013 · External reference
Amyotrophic lateral sclerosis caused by FUS mutations: advances with broad implications
10.1016/s1474-4422(24)00517-9 · 2025 · External reference
Aluminum and Tau in neurofibrillary tangles in familial Alzheimer's disease
10.3233/adr-210011 · 2021 · External reference
Polychlorinated biphenyls (PCBs) in the environment: occupational and exposure events, effects on human health and fertility
10.3390/toxics10070365 · 2022 · External reference
Metal ions shape α-synuclein
10.1038/s41598-020-73207-9 · 2020 · External reference
AA criteria for Alzheimer's disease diagnosis: mainly anchored at Aβ not tau
10.1002/alz.14340 · 2024 · External reference
Frequency and clinical outcomes associated with Tau positron emission tomography positivity
10.1001/jama.2025.7817 · 2025 · External reference
Air pollution, oxidative stress, and Alzheimer's disease
10.1155/2012/472751 · 2012 · External reference
Proteasome 20S and Rab5 alteration after 24 h and 14 days chlorpyrifos exposure lead to β-Amyloid and tau protein level increases and SN56 neuronal cell death
10.1021/acs.chemrestox.9b00216 · 2019 · External reference
Hippocampal sclerosis in advanced age: clinical and pathological features
10.1093/brain/awr053 · 2011 · External reference
Role of environmental toxicants on neurodegenerative disorders
10.3389/ftox.2022.837579 · 2022 · External reference
Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria
10.1212/wnl.51.6.1546 · 1998 · External reference
Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report
10.1093/brain/awz099 · 2019 · External reference
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
10.1126/science.1134108 · 2006 · External reference
Paraquat- and rotenone-induced models of Parkinson's disease
10.1177/039463201102400205 · 2011 · External reference
Ultrafine particles in the urban air: to the respiratory tract--and beyond?
10.1289/ehp.110-1240959 · 2002 · External reference
Translocation of inhaled ultrafine particles to the brain
10.1080/08958370490439597 · 2004 · External reference
Neurotoxicity of polycyclic aromatic hydrocarbons: a systematic mapping and review of neuropathological mechanisms
10.3390/toxics10080417 · 2022 · External reference
Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis
10.1001/jama.2015.4669 · 2015 · External reference
Arsenic exposure: a public health problem leading to several cancers
10.1016/j.yrtph.2019.104539 · 2020 · External reference
Mercury induces the expression of cyclooxygenase-2 and inducible nitric oxide synthase
10.1177/0748233711427048 · 2013 · External reference
α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
10.1038/nature14547 · 2015 · External reference
The role of microglia in the spread of tau: relevance for tauopathies
10.3389/fncel.2018.00172 · 2018 · External reference
Brain atrophy in Alzheimer's disease and aging
10.1016/j.arr.2016.01.002 · 2016 · External reference
Aluminum modulates brain amyloidosis through oxidative stress in APP transgenic mice
10.1096/fj.02-0012fje · 2002 · External reference
Zn2+ modulates in vitro phase separation of TDP-432C and mutant TDP-432C-A315T C-terminal fragments of TDP-43 protein implicated in ALS and FTLD-TDP diseases
10.1016/j.ijbiomac.2021.02.054 · 2021 · External reference
Molecular biology of prion diseases
10.1126/science.1675487 · 1991 · External reference
Rotenone induces cell death in primary dopaminergic culture by increasing ROS production and inhibiting mitochondrial respiration
10.1016/j.neuint.2006.02.003 · 2006 · External reference
The emerging role of autophagy as a target of environmental pollutants: an update on mechanisms
10.3390/toxics11020135 · 2023 · External reference
Environmental chemical exposures and mitochondrial dysfunction: a review of recent literature
10.1007/s40572-022-00371-7 · 2022 · External reference
Polychlorinated biphenyls (PCBs) and neurological development in children: a systematic review
10.1136/jech.55.8.537 · 2001 · External reference
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
10.1038/362059a0 · 1993 · External reference
Protein aggregation and neurodegenerative disease
10.1038/nm1066 · 2004 · External reference
Huntington's disease: from molecular pathogenesis to clinical treatment
10.1016/s1474-4422(10)70245-3 · 2011 · External reference
Extracellular vesicles drive tau spreading in Alzheimer's disease
10.4103/1673-5374.317975 · 2022 · External reference
Rotenone-induced mitochondrial dysfunction, neuroinflammation, oxidative stress, and glial activation in parkinson’s and Alzheimer’s diseases
10.32604/biocell.2025.066320 · 2025 · External reference
Blood-brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders
10.1038/nrneurol.2017.188 · 2018 · External reference
Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease
10.1074/jbc.m111.277061 · 2012 · External reference
Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner
10.1016/j.neuron.2012.03.026 · 2012 · External reference
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes
10.1016/j.cell.2021.09.007 · 2021 · External reference
Association of air pollution with cognitive functions and its modification by APOE gene variants in elderly women
10.1016/j.envres.2015.06.009 · 2015 · External reference
Neuropathology of Lewy body dementia: Lewy-related pathology, α-synuclein oligomers, and comorbid pathologies
10.1186/s13024-025-00900-6 · 2025 · External reference
Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction
10.1126/scitranslmed.aaw8283 · 2019 · External reference
Astrocytes respond to environment-relevant doses TCDD in a specific manner which is different from the endogenous AhR ligand (FICZ)
10.1021/envhealth.4c00189 · 2025 · External reference
Paraquat (herbicide) as a cause of Parkinson's disease
10.1016/j.parkreldis.2023.105932 · 2024 · External reference
Role of astrocytes in manganese mediated neurotoxicity
10.1186/2050-6511-14-23 · 2013 · External reference
Lipopolysaccharide-induced model of neuroinflammation: mechanisms of action, research application and future directions for its use
10.3390/molecules27175481 · 2022 · External reference
Perinatal exposure to bisphenol a alters early adipogenesis in the rat
10.1289/ehp.11342 · 2009 · External reference
Alpha-synuclein in Lewy bodies
10.1038/42166 · 1997 · External reference
Biomarkers and neuroimaging markers in Parkinson's disease
10.1097/cm9.0000000000003745 · 2025 · External reference
Human exposure to microplastics and its associated health risks
10.1021/envhealth.3c00053 · 2023 · External reference
Dieldrin induces ubiquitin-proteasome dysfunction in α-Synuclein overexpressing dopaminergic neuronal cells and enhances susceptibility to apoptotic cell death
10.1124/jpet.105.084632 · 2005 · External reference
Amyloid-β oligomers interact with NMDA receptors containing GluN2B subunits and metabotropic glutamate receptor 1 in primary cortical neurons: relevance to the synapse pathology of Alzheimer’s disease
10.1016/j.neures.2022.03.001 · 2022 · External reference
Rotenone, paraquat, and Parkinson's disease
10.1289/ehp.1002839 · 2011 · External reference
Environmental contamination with polycyclic aromatic hydrocarbons and contribution from biomonitoring studies to the surveillance of global health
10.1007/s11356-024-34727-3 · 2024 · External reference
Microglia in Alzheimer's disease: a role for ion channels
10.3389/fnins.2018.00676 · 2018 · External reference
A common mechanism of proteasome impairment by neurodegenerative disease-associated oligomers
10.1038/s41467-018-03509-0 · 2018 · External reference
Aluminum and Alzheimer's disease: after a century of controversy, is there a plausible link?
10.3233/jad-2010-101494 · 2011 · External reference
Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein
10.1002/ana.410440324 · 1998 · External reference
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
10.1126/science.1165942 · 2009 · External reference
The current role of tau PET imaging in neurodegeneration
10.1053/j.semnuclmed.2025.03.002 · 2025 · External reference
Oxidative stress caused by ozone exposure induces changes in P2X7 receptors, neuroinflammation, and neurodegeneration in the rat hippocampus
10.1155/2021/3790477 · 2021 · External reference
Manganese exposure induces α-synuclein aggregation in the frontal cortex of non-human primates
10.1016/j.toxlet.2012.12.006 · 2013 · External reference
Manganese exposure and cognitive performance: a meta-analytical approach
10.1016/j.envpol.2023.121884 · 2023 · External reference
Perfluorooctane sulfonate triggers tight junction “opening” in brain endothelial cells via phosphatidylinositol 3-kinase
10.1016/j.bbrc.2011.05.128 · 2011 · External reference
PCB 126 induces monocyte/macrophage polarization and inflammation through AhR and NF-κB pathways
10.1016/j.taap.2019.02.006 · 2019 · External reference
Early-life lead exposure induces long-term toxicity in the central nervous system: from zebrafish larvae to juveniles and adults
10.1016/j.scitotenv.2021.150185 · 2022 · External reference
Perfluorooctanoic acid induces hepatocellular endoplasmic reticulum stress and mitochondrial-mediated apoptosis in vitro via endoplasmic reticulum-mitochondria communication
10.1016/j.cbi.2022.109844 · 2022 · External reference
Push-pull effects of basal ganglia network in Parkinson’s disease inferred by functional MRI
10.1038/s41531-024-00835-7 · 2024 · External reference
Lead toxicity: a review
10.1515/intox-2015-0009 · 2015 · External reference
Bisphenol A and phthalates: how environmental chemicals are reshaping toxicology
10.1093/toxsci/kfy232 · 2018 · External reference
The worldwide costs of dementia in 2019
10.1002/alz.12901 · 2023 · External reference
Disruption of synaptic expression pattern and age-related DNA oxidation in a neuronal model of lead-induced toxicity
10.1016/j.etap.2020.103350 · 2020 · External reference
Pesticide exposure and risk of Parkinson's disease: dose-response meta-analysis of observational studies
10.1016/j.yrtph.2018.05.005 · 2018 · External reference
Pollutant-regulated mitophagy: new perspectives in environmental toxicology
10.1007/s10495-025-02242-6 · 2026 · External reference
Hydrophilicity-driven modulation of Amyloid-β(1-40) fibrillation by engineered nanomaterials
10.1021/acsami.5c12708 · 2025 · External reference
Transcriptional and epigenetic regulation of microglia in health and disease
10.1016/j.molmed.2018.11.004 · 2019 · External reference
Dietary intake of persistent organic pollutants and potential health risks via consumption of global aquatic products
10.1002/etc.315 · 2010 · External reference
Brominated flame retardants (BFRs): a review on environmental contamination in China
10.1016/j.chemosphere.2015.12.034 · 2016 · External reference
Polystyrene nanoplastics induce cognitive dysfunction and dendritic spine deterioration via excessive mitochondrial fission
10.1016/j.ecoenv.2025.119133 · 2025 · External reference
Brain endothelial cells release apical and basolateral microparticles in response to inflammatory cytokine stimulation: relevance to neuroinflammatory stress?
10.3389/fimmu.2019.01455 · 2019 · External reference
Single-cell transcriptomic and functional studies identify glial state changes and a role for inflammatory RIPK1 signaling in ALS pathogenesis
10.1016/j.immuni.2025.02.024 · 2025 · External reference
Chlorpyrifos-induced dysregulation of synaptic plasticity in rat hippocampal neurons
10.1080/03601234.2023.2171236 · 2023 · External reference
Environmental contamination and human exposure of polychlorinated biphenyls (PCBs) in China: a review
10.1016/j.scitotenv.2021.150270 · 2022 · External reference
