Research graph
References from Rewriting paracelsus: linking chemical assessment to public health. Local targets link to admitted publications; unresolved targets remain external evidence.
Exposure to low-dose perfluorooctanoic acid promotes hepatic steatosis and disrupts the hepatic transcriptome in mice
10.1016/j.molmet.2022.101602 · 2022 · External reference
A next-generation risk assessment case study for coumarin in cosmetic products
10.1093/toxsci/kfaa048 · 2020 · External reference
Reference dose (RfD): description and use in health risk assessments
10.1016/0273-2300(88)90047-5 · 1988 · External reference
Point of departure (PoD) selection for the derivation of acceptable daily exposures (ADEs) for active pharmaceutical ingredients (APIs)
10.1016/j.yrtph.2016.05.028 · 2016 · External reference
Ab initio chemical safety assessment: a workflow based on exposure considerations and non-animal methods
10.1016/j.comtox.2017.10.001 · 2017 · External reference
The FAIRification process for data stewardship: a comprehensive discourse on the implementation of the FAIR principles for data visibility, interoperability and management
10.1177/03400352241270692 · 2025 · External reference
Relevance and feasibility of principles for health and environmental risk decision-making
10.1080/10937404.2024.2338078 · 2024 · External reference
Multiple stressor effects of insecticide exposure and increased fine sediment deposition on the gene expression profiles of two freshwater invertebrate species
10.1186/s12302-023-00785-6 · 2023 · External reference
Risk assessment in the 21st century: where are we heading?
10.1093/toxres/tfac087 · 2023 · External reference
The estimation and translation uncertainties in applying NOAEL to clinical dose escalation
10.1111/cts.13831 · 2024 · External reference
Exposure considerations in human safety assessment: report from an EPAA partners’ forum
10.1016/j.yrtph.2023.105483 · 2023 · External reference
Addressing the need for safe, nutritious and sustainable food: outcomes of the ONE – Health, environment and society – conference 2022
10.1016/j.tifs.2022.09.014 · 2022 · External reference
Human variability in xenobiotic metabolism and pathway-related uncertainty factors for chemical risk assessment: a review
10.1016/j.fct.2004.05.011 · 2005 · External reference
Unresolved reference
2024 · External reference
Guidance on risk–benefit assessment of foods
10.2903/j.efsa.2024.8875 · 2024 · External reference
A tiered next-generation risk assessment framework integrating toxicokinetics and NAM-Based toxicodynamics: “proof of concept” case study using pyrethroids
10.1007/s00204-025-04045-9 · 2025 · External reference
Next generation risk assessment to address disease-related vulnerability—A proof of concept for the sunscreen octocrylene
10.3390/toxics13020110 · 2025 · External reference
Opportunities for a probabilistic risk assessment of chemicals in the european union
10.1016/s0045-6535(00)00087-4 · 2001 · External reference
Unresolved reference
2010 · External reference
Adverse outcome pathway networks I: development and applications
10.1002/etc.4125 · 2018 · External reference
The threshold of toxicological concern concept in risk assessment
10.1093/toxsci/kfi169 · 2005 · External reference
Role of the synergistic interactions of environmental pollutants in the development of cancer
10.1029/2021gh000552 · 2022 · External reference
Tiered approaches for screening and prioritizing chemicals through integration of pharmacokinetics and exposure information with in vitro dose-response data
10.1016/j.comtox.2019.100101 · 2019 · External reference
Big-data and machine learning to revamp computational toxicology and its use in risk assessment
10.1039/c8tx00051d · 2018 · External reference
Probabilistic risk assessment – the keystone for the future of toxicology
10.14573/altex.2201081 · 2022 · External reference
Theophrastus Bombastus Von Hohenheim (Paracelsus) (1493–1541): the eminent physician and pioneer of toxicology
10.1016/j.toxrep.2021.02.012 · 2021 · External reference
Robust risk assessments require probabilistic approaches
10.1002/ieam.4660 · 2022 · External reference
Guidance on the use of the threshold of toxicological concern approach in food safety assessment
10.2903/j.efsa.2019.5708 · 2019 · External reference
Statement on the derivation of health-based guidance values (HBGVs) for regulated products that are also nutrients
10.2903/j.efsa.2021.6479 · 2021 · External reference
Unresolved reference
2017 · External reference
Unresolved reference
2017 · External reference
Unresolved reference
2019 · External reference
Case study on use of an integrated approach for testing and assessment (IATA) for systemic toxicity of phenoxyethanol when included at 1% in a body lotion
External reference
Guidance document on integrated approaches to testing and assessment (IATA) for serious eye damage and eye irritation
2024 · External reference
Big data technologies: a survey
10.1016/j.jksuci.2017.06.001 · 2018 · External reference
Towards a qAOP framework for predictive toxicology - linking data to decisions
10.1016/j.comtox.2021.100195 · 2022 · External reference
Combination of toxicological and epidemiological approaches for estimating the health impact of atmospheric pollutants. A proof of concept for NO2
10.1016/j.chemosphere.2024.142883 · 2024 · External reference
Joining forces: the chemical biology–medicinal chemistry continuum
10.1016/j.chembiol.2017.05.019 · 2017 · External reference
Human biomonitoring and toxicokinetics as key building blocks for next generation risk assessment
10.1016/j.envint.2024.108474 · 2024 · External reference
Alternatives to animal testing in toxicity testing: current status and future perspectives in food safety assessments
10.1016/j.fct.2023.113944 · 2023 · External reference
Uncertainty in the environmental modelling process – a framework and guidance
10.1016/j.envsoft.2007.02.004 · 2007 · External reference
Unresolved reference
2016 · External reference
New approach methodologies (NAMs): identifying and overcoming hurdles to accelerated adoption
10.1093/toxres/tfae044 · 2024 · External reference
Refined methodologies for probabilistic dietary exposure assessment for food contaminants based on the observed individual means methodology
10.1038/s41370-024-00740-4 · 2025 · External reference
Aggregate exposure pathways in support of risk assessment
10.1016/j.cotox.2018.03.006 · 2018 · External reference
Use of monte carlo simulation and considerations for PK-PD targets to support antibacterial dose selection
10.1016/j.coph.2017.09.009 · 2017 · External reference
Open data ownership and sharing: challenges and opportunities for application of FAIR principles and a checklist for data managers
10.1016/j.jafr.2024.101157 · 2024 · External reference
An overview of methods to evaluate uncertainty of deterministic models in decision support
10.1016/j.envsoft.2014.09.017 · 2015 · External reference
Integration of probabilistic exposure assessment and probabilistic hazard characterization
10.1111/j.1539-6924.2007.00887.x · 2007 · External reference
Application of elements of microbiological risk assessment in the food industry via a tiered approach
10.4315/0362-028x-67.9.2033 · 2004 · External reference
The exposome and health: where chemistry meets biology
10.1126/science.aay3164 · 2020 · External reference
Adverse outcome pathway networks II: network analytics
10.1002/etc.4124 · 2018 · External reference
The adverse outcome pathway concept: a pragmatic tool in toxicology
10.1016/j.tox.2013.08.011 · 2013 · External reference
Unresolved reference
2025 · External reference
The FAIR principles and research data management
10.5206/exfo3999 · 2023 · External reference
Understanding collective behavior in biological systems through potential field mechanisms
10.1038/s41598-025-88440-3 · 2025 · External reference
Bayesian model averaging for probabilistic S-N curves with probability distribution model form uncertainty
10.1016/j.ijfatigue.2023.107955 · 2023 · External reference
