Research graph
References from Porcine interferon-alpha but not interferon-lambda inhibits replication of genotypically diverse PRRSV isolates in vitro. Local targets link to admitted publications; unresolved targets remain external evidence.
Viruses and interferon: a fight for supremacy
10.1038/nri888 · 2002 · External reference
Regulation of effector and memory T-cell functions by type I interferon
10.1111/j.1365-2567.2011.03412.x · 2011 · External reference
Cutting edge: the direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection
10.4049/jimmunol.176.6.3315 · 2006 · External reference
Interferons: success in anti-viral immunotherapy
10.1016/j.cytogfr.2014.07.015 · 2014 · External reference
IL-28 and IL-29: newcomers to the interferon family
10.1016/j.biochi.2007.01.008 · 2007 · External reference
Economic impact of productivity losses attributable to porcine reproductive and respiratory syndrome virus in United States pork production, 2016–2020
10.1016/j.prevetmed.2025.106627 · 2025 · External reference
Interferon-alpha response to swine arterivirus (PoAV), the porcine reproductive and respiratory syndrome virus
10.1089/jir.1998.18.485 · 1998 · External reference
Innate and adaptive immunity against porcine reproductive and respiratory syndrome virus
10.1016/j.vetimm.2015.07.003 · 2015 · External reference
Immunological responses of swine to porcine reproductive and respiratory syndrome virus infection
10.1089/088282402320914485 · 2002 · External reference
Recombinant swine beta interferon protects swine alveolar macrophages and MARC-145 cells from infection with porcine reproductive and respiratory syndrome virus
10.1099/vir.0.82585-0 · 2007 · External reference
IFN gamma inhibits porcine reproductive and respiratory syndrome virus replication in macrophages
10.1007/s007050050578 · 1999 · External reference
Antiviral activity of type I and type III interferons against porcine reproductive and respiratory syndrome virus (PRRSV)
10.1016/j.antiviral.2011.04.017 · 2011 · External reference
Inhibitory effects of recombinant porcine interferon-alpha on high- and low-virulence porcine reproductive and respiratory syndrome viruses
10.1016/j.rvsc.2011.12.006 · 2012 · External reference
Adenovirus-mediated expression of interferon-alpha delays viral replication and reduces disease signs in swine challenged with porcine reproductive and respiratory syndrome virus
10.1089/vim.2008.0075 · 2009 · External reference
The presence of alpha interferon at the time of infection alters the innate and adaptive immune responses to porcine reproductive and respiratory syndrome virus
10.1128/cvi.05490-11 · 2012 · External reference
In vivo and in vitro interferon (IFN) studies with the porcine reproductive and respiratory syndrome virus (PRRSV)
10.1007/978-1-4615-5331-1_59 · 1998 · External reference
Porcine interferon lambda 3 (IFN-lambda 3) shows potent anti-PRRSV activity in primary porcine alveolar macrophages (PAMs)
10.1186/s12917-020-02627-6 · 2020 · External reference
Porcine reproductive and respiratory syndrome virus field isolates differ in in vitro interferon phenotypes
10.1016/j.vetimm.2004.09.009 · 2004 · External reference
The design and recombinant protein expression of a consensus porcine interferon: CoPoIFN-alpha
10.1016/j.cyto.2011.10.011 · 2012 · External reference
Inhibition of porcine reproductive and respiratory syndrome virus by interferon-gamma and recovery of virus replication with 2-aminopurine
10.1007/s007050170161 · 2001 · External reference
PEGylation, successful approach to drug delivery
10.1016/s1359-6446(05)03575-0 · 2005 · External reference
Isolation of swine infertility and respiratory syndrome virus (isolate ATCC VR-2332) in North America and experimental reproduction of the disease in gnotobiotic pigs
10.1177/104063879200400201 · 1992 · External reference
Clinical consequences of exposing pregnant gilts to strains of porcine reproductive and respiratory syndrome (PRRS) virus isolated from field cases of "atypical" PRRS
10.2460/ajvr.1998.59.12.1540 · 1998 · External reference
Pathogenicity and molecular characterization of emerging porcine reproductive and respiratory syndrome virus in Vietnam in 2007
10.1111/j.1865-1682.2010.01152.x · 2010 · External reference
The 30-amino-acid deletion in the Nsp2 of highly pathogenic porcine reproductive and respiratory syndrome virus emerging in China is not related to its virulence
10.1128/jvi.02678-08 · 2009 · External reference
Comparison of Asian porcine high fever disease isolates of porcine reproductive and respiratory syndrome virus to United States isolates for their ability to cause disease and secondary bacterial infection in swine
10.1016/j.vetmic.2017.02.003 · 2017 · External reference
Complete genome analysis of RFLP 184 isolates of porcine reproductive and respiratory syndrome virus
10.1016/j.virusres.2006.06.003 · 2006 · External reference
Genomic sequence and virulence comparison of four type 2 porcine reproductive and respiratory syndrome virus strains
10.1016/j.virusres.2012.07.030 · 2012 · External reference
Mystery swine disease in the Netherlands: the isolation of Lelystad virus
10.1080/01652176.1991.9694296 · 1991 · External reference
Homologous challenge of porcine reproductive and respiratory syndrome virus immunity in pregnant swine
10.1016/s0378-1135(97)00160-0 · 1997 · External reference
Experimental reproduction of severe disease in CD/CD pigs concurrently infected with type 2 porcine circovirus and porcine reproductive and respiratory syndrome virus
10.1354/vp.38-5-528 · 2001 · External reference
Phagocytosis by pig alveolar macrophages of Actinobacillus pleuropneumoniae serotype 2 mutant strains defective in haemolysin II (ApxII) and pleurotoxin (ApxIII)
10.1099/13500872-140-2-237 · 1994 · External reference
Heterogeneity of swine lung macrophages inoculated by porcine reproductive and respiratory syndrome virus
10.1080/09540105.2016.1160366 · 2016 · External reference
A simple method of estimating fifty percent endpoints
1938 · External reference
Development of a genome copy specific RT-qPCR assay for divergent strains of type 2 porcine reproductive and respiratory syndrome virus
10.1016/j.jviromet.2015.02.007 · 2015 · External reference
Innate cytokine responses in porcine macrophage populations: evidence for differential recognition of double-stranded RNA
10.4049/jimmunol.177.12.8432 · 2006 · External reference
Coinfection of pigs with porcine respiratory coronavirus and Bordetella bronchiseptica
10.1016/j.vetmic.2007.09.025 · 2008 · External reference
Porcine ISG15 fused IFN-lambda3 as a novel antiviral agent for treating porcine reproductive and respiratory syndrome virus infection in vivo
10.1016/j.ijbiomac.2024.138242 · 2025 · External reference
Marked differences between MARC-145 cells and swine alveolar macrophages in IFNbeta-induced activation of antiviral state against PRRSV
10.1016/j.vetimm.2010.07.023 · 2011 · External reference
Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes
10.1189/jlb.0807525 · 2008 · External reference
IFN-lambda: a new inducer of local immunity against cancer and infections
10.3389/fimmu.2016.00598 · 2016 · External reference
Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines
10.1038/gene.2009.72 · 2009 · External reference
Rational design of a potent, long-lasting form of interferon: a 40 kDa branched polyethylene glycol-conjugated interferon alpha-2a for the treatment of hepatitis C
10.1021/bc000082g · 2001 · External reference
Solid-phase PEGylation of recombinant interferon alpha-2a for site-specific modification: process performance, characterization, and in vitro bioactivity
10.1021/bc060245m · 2007 · External reference
