Research graph
References from Extracellular Vesicles and Their Role in Osteogenesis. Local targets link to admitted publications; unresolved targets remain external evidence.
Cd9+ and cd82+ extracellular vesicles in synovial fluid differentiate aseptic from septic endoprosthesis loosening
10.20517/evcna.2025.11 · 2025 · External reference
A native bioactive interface functionalized with osteoprogenitor stem cell-derived migrasomes for enhanced bone regeneration
10.34133/research.1220 · 2026 · External reference
10.3390/biology12010110
10.3390/biology12010110 · External reference
10.3390/cells8070727
10.3390/cells8070727 · External reference
Phase 2 of extracellular rna communication consortium charts next-generation approaches for extracellular rna research
10.1016/j.isci.2022.104653 · 2022 · External reference
The extracellular rna communication consortium: Establishing foundational knowledge and technologies for extracellular rna research
10.1016/j.cell.2019.03.023 · 2019 · External reference
Minimal information for studies of extracellular vesicles 2018 (misev2018): A position statement of the international society for extracellular vesicles and update of the misev2014 guidelines
10.1080/20013078.2018.1535750 · 2018 · External reference
Potential functional applications of extracellular vesicles: A report by the nih common fund extracellular rna communication consortium
10.3402/jev.v4.27575 · 2015 · External reference
Minimal experimental requirements for definition of extracellular vesicles and their functions: A position statement from the international society for extracellular vesicles
10.3402/jev.v3.26913 · 2014 · External reference
Minimal information for studies of extracellular vesicles (misev2023): From basic to advanced approaches
10.1002/jev2.12404 · 2024 · External reference
Extracellular vesicles for tissue repair and regeneration: Evidence, challenges and opportunities
10.1016/j.addr.2021.04.013 · 2021 · External reference
Exosomes: The next generation of endogenous nanomaterials for advanced drug delivery and therapy
10.1016/j.actbio.2018.12.045 · 2019 · External reference
Exosomes in therapy: Engineering, pharmacokinetics and future applications
10.2174/1389450119666180521100409 · 2019 · External reference
Vaccination of metastatic melanoma patients with autologous dendritic cell (dc) derived-exosomes: Results of thefirst phase i clinical trial
10.1186/1479-5876-3-10 · 2005 · External reference
10.3389/fgene.2022.915141
10.3389/fgene.2022.915141 · External reference
Research progress on exosomes in osteonecrosis of the femoral head
10.1111/os.13393 · 2022 · External reference
10.3389/fbioe.2023.1050916
10.3389/fbioe.2023.1050916 · External reference
The multifaceted roles of extracellular vesicles in osteonecrosis of the femoral head
2025 · External reference
Exosomes derived from mir-375-overexpressing human adipose mesenchymal stem cells promote bone regeneration
10.1111/cpr.12669 · 2019 · External reference
Hijacking the cellular mail: Exosome mediated differentiation of mesenchymal stem cells
10.1155/2016/3808674 · 2016 · External reference
Surgical vacuum filter-derived stromal cells are superior in proliferation to human bone marrow aspirate
10.1186/s13287-019-1461-0 · 2019 · External reference
10.3390/ijms242115877
10.3390/ijms242115877 · External reference
Surgical suction filter-derived bone graft displays osteogenic mirna and mrna patterns
10.1007/s00068-023-02350-5 · 2024 · External reference
10.3390/jfb16090340
10.3390/jfb16090340 · External reference
Bioactivation of scaffolds in osteonecrosis
2022 · External reference
10.3390/jfb17050245
10.3390/jfb17050245 · External reference
10.3390/biom16020289
10.3390/biom16020289 · External reference
10.3390/bioengineering8100137
10.3390/bioengineering8100137 · External reference
10.3389/fbioe.2020.01015
10.3389/fbioe.2020.01015 · External reference
Stem cell-derived exosomes in bone healing: Focusing on their role in angiogenesis
10.1016/j.jcyt.2022.08.008 · 2023 · External reference
10.3390/biomedicines14030495
10.3390/biomedicines14030495 · External reference
Migrasome: A new functional extracellular vesicle
10.1038/s41420-023-01673-x · 2023 · External reference
M2 microglia-derived migrasome-enriched extracellular vesicles restore mitochondrial homeostasis to orchestrate neurovascular unit recovery after ischemic stroke
10.1186/s12951-026-04643-4 · 2026 · External reference
M2 macrophage-derived migrasomes enhance bone regeneration by directing osteogenic differentiation of bone marrow mesenchymal stem cells (bmscs)
10.1016/j.tice.2026.103394 · 2026 · External reference
How apoptotic cells aid in the removal of their own cold dead bodies
10.1038/cdd.2012.25 · 2012 · External reference
Apoptotic extracellular vesicles act as master regulators of the bone healing niche
10.1186/s12951-026-04351-z · 2026 · External reference
Engineering mesenchymal stem cells to improve their exosome efficacy and yield for cell-free therapy
10.1080/20013078.2018.1522236 · 2018 · External reference
Bone marrow stromal/stem cell-derived extracellular vesicles regulate osteoblast activity and differentiation in vitro and promote bone regeneration in vivo
10.1038/srep21961 · 2016 · External reference
Human mesenchymal stem cell derived exosomes enhance cell-free bone regeneration by altering their mirnas profiles
10.1002/advs.202001334 · 2020 · External reference
Lncrna malat1 shuttled by bone marrow-derived mesenchymal stem cells-secreted exosomes alleviates osteoporosis through mediating microrna-34c/satb2 axis
10.18632/aging.102264 · 2019 · External reference
Efficient cellular transformation via protein delivery through the protrusion-derived extracellular vesicles
10.1038/s41467-025-66351-1 · 2025 · External reference
Exosomal mir-335 derived from mature dendritic cells enhanced mesenchymal stem cell-mediated bone regeneration of bone defects in athymic rats
10.1186/s10020-021-00268-5 · 2021 · External reference
Exosomes secreted by human-induced pluripotent stem cell-derived mesenchymal stem cells repair critical-sized bone defects through enhanced angiogenesis and osteogenesis in osteoporotic rats
10.7150/ijbs.14809 · 2016 · External reference
Exosomes/tricalcium phosphate combination scaffolds can enhance bone regeneration by activating the pi3k/akt signaling pathway
10.1186/s13287-016-0391-3 · 2016 · External reference
Tissue-engineered bone immobilized with human adipose stem cells-derived exosomes promotes bone regeneration
10.1021/acsami.7b17620 · 2018 · External reference
Identification and proteomic analysis of osteoblast-derived exosomes
10.1016/j.bbrc.2015.09.135 · 2015 · External reference
Value of osteoblast-derived exosomes in bone diseases
10.1097/scs.0000000000003463 · 2017 · External reference
Biomimetic synthesis and optimization of extracellular vesicles for bone regeneration
10.1016/j.jconrel.2023.01.057 · 2023 · External reference
10.3390/ijms23031865
10.3390/ijms23031865 · External reference
Pc-3-derived exosomes inhibit osteoclast differentiation by downregulating mir-214 and blocking nf-kappab signaling pathway
10.1155/2019/8650846 · 2019 · External reference
10.1371/journal.pone.0166284
10.1371/journal.pone.0166284 · External reference
Adipose mesenchymal stem cell-derived exosomes ameliorate hypoxia/serum deprivation-induced osteocyte apoptosis and osteocyte-mediated osteoclastogenesis in vitro
10.1016/j.bbrc.2018.11.109 · 2019 · External reference
Reversal of osteoporotic activity by endothelial cell-secreted bone targeting and biocompatible exosomes
10.1021/acs.nanolett.9b00287 · 2019 · External reference
Osteoclast-derived mir-23a-5p-containing exosomes inhibit osteogenic differentiation by regulating runx2
10.1016/j.cellsig.2019.109504 · 2020 · External reference
Osteoclast-derived exosomal mir-214-3p inhibits osteoblastic bone formation
10.1038/ncomms10872 · 2016 · External reference
Synergistic protection of bone vasculature and bone mass by desferrioxamine in osteoporotic mice
10.3892/mmr.2017.7451 · 2017 · External reference
Deferoxamine released from poly(lactic-co-glycolic acid) promotes healing of osteoporotic bone defect via enhanced angiogenesis and osteogenesis
10.1002/jbm.a.35793 · 2016 · External reference
Exosomes secreted by endothelial progenitor cells accelerate bone regeneration during distraction osteogenesis by stimulating angiogenesis
10.1186/s13287-018-1115-7 · 2019 · External reference
10.3390/ijms18091852
10.3390/ijms18091852 · External reference
Injectable composite hydrogel promotes osteogenesis and angiogenesis in spinal fusion by optimizing the bone marrow mesenchymal stem cell microenvironment and exosomes secretion
10.1016/j.msec.2020.111782 · 2021 · External reference
10.3389/fbioe.2021.829136
10.3389/fbioe.2021.829136 · External reference
The hippo-taz axis mediates vascular endothelial growth factor c in glioblastoma-derived exosomes to promote angiogenesis
10.1016/j.canlet.2021.05.002 · 2021 · External reference
10.1371/journal.pone.0225472
10.1371/journal.pone.0225472 · External reference
Exosomes from bone marrow mesenchymal stem cells enhance fracture healing through the promotion of osteogenesis and angiogenesis in a rat model of nonunion
10.1186/s13287-020-1562-9 · 2020 · External reference
Dynamically bioresponsive DNA hydrogel incorporated with dual-functional stem cells from apical papilla-derived exosomes promotes diabetic bone regeneration
10.1021/acsami.2c02278 · 2022 · External reference
Lithium-containing biomaterials stimulate bone marrow stromal cell-derived exosomal mir-130a secretion to promote angiogenesis
10.1016/j.biomaterials.2018.11.007 · 2019 · External reference
Hypoxic mesenchymal stem cell-derived exosomes promote bone fracture healing by the transfer of mir-126
10.1016/j.actbio.2019.12.020 · 2020 · External reference
Mesenchymal stem cells-derived exosomes are more immunosuppressive than microparticles in inflammatory arthritis
10.7150/thno.21072 · 2018 · External reference
10.3389/fvets.2017.00039
10.3389/fvets.2017.00039 · External reference
Antigen presentation by extracellular vesicles from professional antigen-presenting cells
10.1146/annurev-immunol-041015-055700 · 2018 · External reference
Immunosuppressive effects of mesenchymal stem cells-derived exosomes
10.1007/s12015-020-10040-7 · 2021 · External reference
Immunomodulatory effects of mesenchymal stromal cells-derived exosome
10.1007/s12026-016-8798-6 · 2016 · External reference
Latest perspectives on macrophages in bone homeostasis
10.1007/s00424-017-1952-8 · 2017 · External reference
1,25-dihydroxyvitamin d suppresses m1 macrophages and promotes m2 differentiation at bone injury sites
10.1172/jci.insight.98773 · 2018 · External reference
Exosome-loaded extracellular matrix-mimic hydrogel with anti-inflammatory property facilitates/promotes growth plate injury repair
2022 · External reference
Advanced plga hybrid scaffold with a bioactive pdrn/bmp2 nanocomplex for angiogenesis and bone regeneration using human fetal mscs
10.1126/sciadv.abj1083 · 2021 · External reference
A notch1/lsd1/bmp2 co-regulatory network mediated by mir-137 negatively regulates osteogenesis of human adipose-derived stem cells
10.1186/s13287-021-02495-3 · 2021 · External reference
Exosomes from adipose-derived stem cells regulate m1/m2 macrophage phenotypic polarization to promote bone healing via mir-451a/mif
10.1186/s13287-022-02823-1 · 2022 · External reference
The role of exosomes in bone remodeling: Implications for bone physiology and disease
10.1155/2019/9417914 · 2019 · External reference
Exosomal miR-1a-3p derived from glucocorticoid-stimulated M1 macrophages promotes the adipogenic differentiation of BMSCs in glucocorticoid-associated osteonecrosis of the femoral head by targeting Cebpz
10.1186/s12951-024-02923-5 · 2024 · External reference
Adipocyte-secreted microvesicle-derived miR-148a regulates adipogenic and osteogenic differentiation by targeting Wnt5a/Ror2 pathway
10.1016/j.lfs.2021.119548 · 2021 · External reference
Low miR-182-5p expressing extracellular vesicles derived from human bone marrow stromal cells of subjects with steroid-induced osteonecrosis of the femoral head aggravate disease progression
10.1002/jbmr.4823 · 2023 · External reference
Elevated level of membrane microparticles in the disease of steroid-induced vascular osteonecrosis
10.1097/scs.0b013e3182902dd3 · 2013 · External reference
Circulating platelet-derived microparticles and endothelium-derived microparticles may be a potential cause of microthrombosis in patients with osteonecrosis of the femoral head
10.1016/j.thromres.2008.04.001 · 2008 · External reference
MicroRNA sequence analysis of plasma exosomes in early Legg-Calvé-Perthes disease
10.1016/j.cellsig.2021.110184 · 2022 · External reference
Progenitor cell-derived exosomes endowed with vegf plasmids enhance osteogenic induction and vascular remodeling in large segmental bone defects
10.7150/thno.50741 · 2021 · External reference
Mesenchymal stem cell-derived microvesicles mediate bmp2 gene delivery and enhance bone regeneration
10.1039/d0tb00422g · 2020 · External reference
10.3389/fbioe.2017.00068
10.3389/fbioe.2017.00068 · External reference
Osteoblast-derived vegf regulates osteoblast differentiation and bone formation during bone repair
10.1172/jci82585 · 2016 · External reference
Development of exosome surface display technology in living human cells
10.1016/j.bbrc.2016.02.058 · 2016 · External reference
Exosome-guided bone targeted delivery of antagomir-188 as an anabolic therapy for bone loss
2021 · External reference
Extracellular vesicles derived from osteogenically induced human bone marrow mesenchymal stem cells can modulate lineage commitment
10.1016/j.stemcr.2016.01.001 · 2016 · External reference
Exosomes secreted from mutant-hif-1alpha-modified bone-marrow-derived mesenchymal stem cells attenuate early steroid-induced avascular necrosis of femoral head in rabbit
10.1002/cbin.10869 · 2017 · External reference
10.3389/fbioe.2020.565561
10.3389/fbioe.2020.565561 · External reference
Evaluation of electroporation-induced adverse effects on adipose-derived stem cell exosomes
10.1007/s10616-016-9952-7 · 2016 · External reference
Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: A new approach for drug delivery
10.1016/j.jconrel.2014.07.042 · 2014 · External reference
Lineage-specific exosomes could override extracellular matrix mediated human mesenchymal stem cell differentiation
10.1016/j.biomaterials.2018.08.027 · 2018 · External reference
Optimized bmsc-derived osteoinductive exosomes immobilized in hierarchical scaffold via lyophilization for bone repair through bmpr2/acvr2b competitive receptor-activated smad pathway
10.1016/j.biomaterials.2021.120718 · 2021 · External reference
Dimethyloxaloylglycine-stimulated human bone marrow mesenchymal stem cell-derived exosomes enhance bone regeneration through angiogenesis by targeting the akt/mtor pathway
10.1186/s13287-019-1410-y · 2019 · External reference
Early-responsive immunoregulation therapy improved microenvironment for bone regeneration via engineered extracellular vesicles
10.1002/adhm.202303681 · 2023 · External reference
Functionally engineered extracellular vesicles improve bone regeneration
10.1016/j.actbio.2020.04.017 · 2020 · External reference
Exosome-integrated titanium oxide nanotubes for targeted bone regeneration
10.1016/j.actbio.2019.01.006 · 2019 · External reference
Periodontal tissue regeneration using the cytokine cocktail mimicking secretomes in the conditioned media from human mesenchymal stem cells
10.1016/j.bbrc.2017.01.065 · 2017 · External reference
Development of exosome-encapsulated paclitaxel to overcome mdr in cancer cells
10.1016/j.nano.2015.10.012 · 2016 · External reference
Active loading into extracellular vesicles significantly improves the cellular uptake and photodynamic effect of porphyrins
10.1016/j.jconrel.2014.11.029 · 2015 · External reference
Inhibiting collagen i production and tumor cell colonization in the lung via mir-29a-3p loading of exosome-/liposome-based nanovesicles
10.1016/j.apsb.2021.08.011 · 2022 · External reference
Aptamer-conjugated extracellular nanovesicles for targeted drug delivery
10.1158/0008-5472.can-17-2880 · 2018 · External reference
Bioinspired nanovesicles convert the skeletal endothelium-associated secretory phenotype to treat osteoporosis
10.1021/acsnano.2c03781 · 2022 · External reference
Engineering hybrid exosomes by membrane fusion with liposomes
10.1038/srep21933 · 2016 · External reference
Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy
10.1016/j.biomaterials.2017.10.012 · 2018 · External reference
Microfluidic on-demand engineering of exosomes towards cancer immunotherapy
10.1039/c8lc01279b · 2019 · External reference
Hydrogel armed with Bmp2 mRNA-enriched exosomes enhances bone regeneration
10.1186/s12951-023-01871-w · 2023 · External reference
Exosomal mRNAs for Angiogenic-Osteogenic Coupled Bone Repair
10.1002/advs.202302622 · 2023 · External reference
Cell trafficking and regulation of osteoblastogenesis by extracellular vesicle associated bone morphogenetic protein 2
10.1002/jev2.12155 · 2021 · External reference
Engineered BMP2/BMP7 extracellular vesicles induce autocrine BMP release driving SMAD phosphorylation to promote bone formation
10.1038/s41536-025-00405-2 · 2025 · External reference
Designer exosomes: A new platform for biotechnology therapeutics
10.1007/s40259-020-00434-x · 2020 · External reference
Biomimetic composite hydrogel promotes new bone formation in rat bone defects through regulation of mir-19b-3p/wwp1 axis by loaded extracellular vesicles
10.1186/s12951-023-02201-w · 2023 · External reference
Self-assembled human adipose-derived stem cell-derived extracellular vesicle-functionalized biotin-doped polypyrrole titanium with long-term stability and potential osteoinductive ability
10.1021/acsami.9b17015 · 2019 · External reference
Small extracellular vesicles released from bioglass/hydrogel scaffold promote vascularized bone regeneration by transferring mir-23a-3p
10.2147/ijn.s389471 · 2022 · External reference
Osteoinductive dental pulp stem cell-derived extracellular vesicle-loaded multifunctional hydrogel for bone regeneration
10.1021/acsnano.3c11542 · 2024 · External reference
Mesenchymal stem cells release exosomes that transfer mirnas to endothelial cells and promote angiogenesis
10.18632/oncotarget.16778 · 2017 · External reference
Mesenchymal stem cells-derived extracellular vesicles, via mir-210, improve infarcted cardiac function by promotion of angiogenesis
10.1016/j.bbadis.2017.02.023 · 2017 · External reference
Extracellular vesicles in angiogenesis
10.1161/circresaha.117.309681 · 2017 · External reference
Generation of small rna-modulated exosome mimetics for bone regeneration
10.1021/acsnano.0c05122 · 2020 · External reference
Therapeutic efficacy of mesenchymal stem cell-derived extracellular vesicles combined with injectable hydrogels in bone defect repair: A systematic review and meta-analysis of preclinical studies
10.1186/s13036-026-00684-3 · 2026 · External reference
Self-assembled biodegradable nanoparticles and polysaccharides as biomimetic ecm nanostructures for the synergistic effect of rgd and bmp-2 on bone formation
10.1038/srep25090 · 2016 · External reference
Extracellular vesicle-integrated biomaterials in bone tissue engineering applications: Current progress and future perspectives
10.2147/ijn.s522198 · 2025 · External reference
Aptamer-functionalized exosomes: Elucidating the cellular uptake mechanism and the potential for cancer-targeted chemotherapy
10.1021/acs.analchem.8b05204 · 2019 · External reference
A bone-targeted engineered exosome platform delivering sirna to treat osteoporosis
2022 · External reference
Modification of adipose mesenchymal stem cells-derived small extracellular vesicles with fibrin-targeting peptide creka for enhanced bone repair
2023 · External reference
Exosome-mimetics as an engineered gene-activated matrix induces in-situ vascularized osteogenesis
10.1016/j.biomaterials.2020.119985 · 2020 · External reference
Artificial extracellular matrices composed of collagen i and high-sulfated hyaluronan promote phenotypic and functional modulation of human pro-inflammatory m1 macrophages
10.1016/j.actbio.2012.11.016 · 2013 · External reference
Extracellular vesicles in osteoimmunomodulation: Orchestrating immune-driven bone regeneration
10.1016/j.ijbiomac.2025.149614 · 2026 · External reference
Osteo-immunomodulatory effects of macrophage-derived extracellular vesicles treated with biphasic calcium phosphate ceramics on bone regeneration
10.1088/1748-605x/ad5242 · 2024 · External reference
10.1101/2024.09.17.613483
10.1101/2024.09.17.613483 · External reference
Extracellular vesicles for macrophage reprogramming: An emerging paradigm in immunomodulatory therapeutics
10.1186/s13036-025-00594-w · 2025 · External reference
Immunomodulation with m2 macrophage-derived extracellular vesicles for enhanced titanium implant osseointegration under diabetic conditions
10.1016/j.mtbio.2024.101385 · 2025 · External reference
Extracellular vesicle mobility in collagen i hydrogels is influenced by matrix-binding integrins
10.1021/acsnano.4c07186 · 2024 · External reference
Bone-targeted extracellular vesicles from mesenchymal stem cells for osteoporosis therapy
10.2147/ijn.s263756 · 2020 · External reference
High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources
10.3402/jev.v5.32570 · 2016 · External reference
Integrated isolation and quantitative analysis of exosome shuttled proteins and nucleic acids using immunocapture approaches
10.1016/j.ymeth.2015.05.028 · 2015 · External reference
Isolation of biologically-active exosomes from human plasma
10.1016/j.jim.2014.06.007 · 2014 · External reference
Isolation of exosomes by differential centrifugation: Theoretical analysis of a commonly used protocol
10.1038/srep17319 · 2015 · External reference
A novel strategy for facile serum exosome isolation based on specific interactions between phospholipid bilayers and tio(2)
10.1039/c8sc04197k · 2019 · External reference
Methods and technologies for exosome isolation and characterization
10.1002/smtd.201800021 · 2018 · External reference
Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line lim1863-derived exosomes
10.1016/j.ymeth.2012.01.002 · 2012 · External reference
Exosomes--vesicular carriers for intercellular communication
10.1016/j.ceb.2009.03.007 · 2009 · External reference
Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury
10.1093/ndt/gfr015 · 2011 · External reference
10.3390/cells11020186
10.3390/cells11020186 · External reference
Approaches to surface engineering of extracellular vesicles
10.1016/j.addr.2021.03.020 · 2021 · External reference
Bm-msc-derived exosomes alleviate radiation-induced bone loss by restoring the function of recipient bm-mscs and activating wnt/beta-catenin signaling
10.1186/s13287-018-1121-9 · 2019 · External reference
Functional extracellular vesicles enable injectable hydrogels with stable osteogenic properties for minimally invasive bone defect repair
10.1038/s41598-025-32018-6 · 2025 · External reference
Mesenchymal stem cell-derived exosome nr4a2 inhibits fracture healing in aged rat by blocking nell2-mediated osteogenic differentiation
10.1016/j.molimm.2026.07.010 · 2026 · External reference
Unresolved reference
External reference
Mir-329-3p in bone marrow mesenchymal stem cells-derived exosomes promotes bone regeneration in diabetic fractures by alleviating the sirt3-mediated oxidative stress via inhibiting lsd1
10.1155/sci/6280416 · 2026 · External reference
Clinical potential of mesenchymal stem/stromal cell-derived extracellular vesicles
10.21037/sci.2017.09.06 · 2017 · External reference
A critical systematic review of extracellular vesicle clinical trials
10.1002/jev2.12510 · 2024 · External reference
Harnessing extracellular vesicle heterogeneity for diagnostic and therapeutic applications
10.1038/s41565-024-01774-3 · 2025 · External reference
Engineering challenges and translational opportunities in emerging gene delivery platforms
10.1038/s41551-026-01643-5 · 2026 · External reference
Early-responsive immunoregulation therapy improved microenvironment for bone regeneration via engineered extracellular vesicles
10.1002/adhm.202303681 · ExternalCitation · doi-reference
Human mesenchymal stem cell derived exosomes enhance cell-free bone regeneration by altering their mirnas profiles
10.1002/advs.202001334 · ExternalCitation · doi-reference
Exosomal mRNAs for Angiogenic-Osteogenic Coupled Bone Repair
10.1002/advs.202302622 · ExternalCitation · doi-reference
Exosomes secreted from mutant-hif-1alpha-modified bone-marrow-derived mesenchymal stem cells attenuate early steroid-induced avascular necrosis of femoral head in rabbit
10.1002/cbin.10869 · ExternalCitation · doi-reference
Deferoxamine released from poly(lactic-co-glycolic acid) promotes healing of osteoporotic bone defect via enhanced angiogenesis and osteogenesis
10.1002/jbm.a.35793 · ExternalCitation · doi-reference
Low miR-182-5p expressing extracellular vesicles derived from human bone marrow stromal cells of subjects with steroid-induced osteonecrosis of the femoral head aggravate disease progression
10.1002/jbmr.4823 · ExternalCitation · doi-reference
Cell trafficking and regulation of osteoblastogenesis by extracellular vesicle associated bone morphogenetic protein 2
10.1002/jev2.12155 · ExternalCitation · doi-reference
Minimal information for studies of extracellular vesicles (misev2023): From basic to advanced approaches
10.1002/jev2.12404 · ExternalCitation · doi-reference
A critical systematic review of extracellular vesicle clinical trials
10.1002/jev2.12510 · ExternalCitation · doi-reference
Methods and technologies for exosome isolation and characterization
10.1002/smtd.201800021 · ExternalCitation · doi-reference
Surgical suction filter-derived bone graft displays osteogenic mirna and mrna patterns
10.1007/s00068-023-02350-5 · ExternalCitation · doi-reference
Latest perspectives on macrophages in bone homeostasis
10.1007/s00424-017-1952-8 · ExternalCitation · doi-reference
Evaluation of electroporation-induced adverse effects on adipose-derived stem cell exosomes
10.1007/s10616-016-9952-7 · ExternalCitation · doi-reference
Immunosuppressive effects of mesenchymal stem cells-derived exosomes
10.1007/s12015-020-10040-7 · ExternalCitation · doi-reference
Immunomodulatory effects of mesenchymal stromal cells-derived exosome
10.1007/s12026-016-8798-6 · ExternalCitation · doi-reference
Designer exosomes: A new platform for biotechnology therapeutics
10.1007/s40259-020-00434-x · ExternalCitation · doi-reference
Artificial extracellular matrices composed of collagen i and high-sulfated hyaluronan promote phenotypic and functional modulation of human pro-inflammatory m1 macrophages
10.1016/j.actbio.2012.11.016 · ExternalCitation · doi-reference
Exosomes: The next generation of endogenous nanomaterials for advanced drug delivery and therapy
10.1016/j.actbio.2018.12.045 · ExternalCitation · doi-reference
Exosome-integrated titanium oxide nanotubes for targeted bone regeneration
10.1016/j.actbio.2019.01.006 · ExternalCitation · doi-reference
Hypoxic mesenchymal stem cell-derived exosomes promote bone fracture healing by the transfer of mir-126
10.1016/j.actbio.2019.12.020 · ExternalCitation · doi-reference
Functionally engineered extracellular vesicles improve bone regeneration
10.1016/j.actbio.2020.04.017 · ExternalCitation · doi-reference
Approaches to surface engineering of extracellular vesicles
10.1016/j.addr.2021.03.020 · ExternalCitation · doi-reference
Extracellular vesicles for tissue repair and regeneration: Evidence, challenges and opportunities
10.1016/j.addr.2021.04.013 · ExternalCitation · doi-reference
Inhibiting collagen i production and tumor cell colonization in the lung via mir-29a-3p loading of exosome-/liposome-based nanovesicles
10.1016/j.apsb.2021.08.011 · ExternalCitation · doi-reference
Mesenchymal stem cells-derived extracellular vesicles, via mir-210, improve infarcted cardiac function by promotion of angiogenesis
10.1016/j.bbadis.2017.02.023 · ExternalCitation · doi-reference
Identification and proteomic analysis of osteoblast-derived exosomes
10.1016/j.bbrc.2015.09.135 · ExternalCitation · doi-reference
Development of exosome surface display technology in living human cells
10.1016/j.bbrc.2016.02.058 · ExternalCitation · doi-reference
Periodontal tissue regeneration using the cytokine cocktail mimicking secretomes in the conditioned media from human mesenchymal stem cells
10.1016/j.bbrc.2017.01.065 · ExternalCitation · doi-reference
Adipose mesenchymal stem cell-derived exosomes ameliorate hypoxia/serum deprivation-induced osteocyte apoptosis and osteocyte-mediated osteoclastogenesis in vitro
10.1016/j.bbrc.2018.11.109 · ExternalCitation · doi-reference
Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy
10.1016/j.biomaterials.2017.10.012 · ExternalCitation · doi-reference
Lineage-specific exosomes could override extracellular matrix mediated human mesenchymal stem cell differentiation
10.1016/j.biomaterials.2018.08.027 · ExternalCitation · doi-reference
Lithium-containing biomaterials stimulate bone marrow stromal cell-derived exosomal mir-130a secretion to promote angiogenesis
10.1016/j.biomaterials.2018.11.007 · ExternalCitation · doi-reference
Exosome-mimetics as an engineered gene-activated matrix induces in-situ vascularized osteogenesis
10.1016/j.biomaterials.2020.119985 · ExternalCitation · doi-reference
Optimized bmsc-derived osteoinductive exosomes immobilized in hierarchical scaffold via lyophilization for bone repair through bmpr2/acvr2b competitive receptor-activated smad pathway
10.1016/j.biomaterials.2021.120718 · ExternalCitation · doi-reference
The hippo-taz axis mediates vascular endothelial growth factor c in glioblastoma-derived exosomes to promote angiogenesis
10.1016/j.canlet.2021.05.002 · ExternalCitation · doi-reference
Exosomes--vesicular carriers for intercellular communication
10.1016/j.ceb.2009.03.007 · ExternalCitation · doi-reference
The extracellular rna communication consortium: Establishing foundational knowledge and technologies for extracellular rna research
10.1016/j.cell.2019.03.023 · ExternalCitation · doi-reference
Osteoclast-derived mir-23a-5p-containing exosomes inhibit osteogenic differentiation by regulating runx2
10.1016/j.cellsig.2019.109504 · ExternalCitation · doi-reference
MicroRNA sequence analysis of plasma exosomes in early Legg-Calvé-Perthes disease
10.1016/j.cellsig.2021.110184 · ExternalCitation · doi-reference
Extracellular vesicles in osteoimmunomodulation: Orchestrating immune-driven bone regeneration
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