Research graph
References from Exploratory Transcriptomic, Genomic, Pharmacogenomic, and Cellular Evaluation of FKBP4 in Lung Adenocarcinoma. Local targets link to admitted publications; unresolved targets remain external evidence.
Global Cancer Statistics 2022: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2024 · External reference
The Biology and Management of Non-Small Cell Lung Cancer
10.1038/nature25183 · 2018 · External reference
Lung Cancer
10.1016/s0140-6736(21)00312-3 · 2021 · External reference
Tumour Heterogeneity and Resistance to Cancer Therapies
10.1038/nrclinonc.2017.166 · 2018 · External reference
The HSP90 Chaperone Machinery
10.1038/nrm.2017.20 · 2017 · External reference
FKBP51 and FKBP52 in Signaling and Disease
10.1016/j.tem.2011.08.001 · 2011 · External reference
FK506-Binding Proteins 51 and 52 Differentially Regulate Dynein Interaction and Nuclear Translocation of the Glucocorticoid Receptor in Mammalian Cells
10.1074/jbc.m407498200 · 2005 · External reference
FKBP4 Connects mTORC2 and PI3K to Activate the PDK1/Akt-Dependent Cell Proliferation Signaling in Breast Cancer
10.7150/thno.35561 · 2019 · External reference
Delineation of Human Prostate Cancer Evolution Identifies Chromothripsis as a Polyclonal Event and FKBP4 as a Potential Driver of Castration Resistance
10.1002/path.5052 · 2018 · External reference
Targeting the Regulation of Androgen Receptor Signaling by the Heat Shock Protein 90 Cochaperone FKBP52 in Prostate Cancer Cells
10.1073/pnas.1105160108 · 2011 · External reference
FKBP4 Integrates FKBP4/Hsp90/IKK with FKBP4/Hsp70/RelA Complex to Promote Lung Adenocarcinoma Progression via IKK/NF-κB Signaling
10.1038/s41419-021-03857-8 · 2021 · External reference
Using Bioinformatic Analysis to Identify FK506 Binding Protein 4 as a Novel Prognostic Factor in Lung Adenocarcinoma
2023 · External reference
TCGAbiolinks: An R/Bioconductor Package for Integrative Analysis of TCGA Data
10.1093/nar/gkv1507 · 2016 · External reference
Toward a Shared Vision for Cancer Genomic Data
10.1056/nejmp1607591 · 2016 · External reference
Gene Set Enrichment Analysis: A Knowledge-Based Approach for Interpreting Genome-Wide Expression Profiles
10.1073/pnas.0506580102 · 2005 · External reference
The Molecular Signatures Database (MSigDB) Hallmark Gene Set Collection
10.1016/j.cels.2015.12.004 · 2015 · External reference
The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data
10.1158/2159-8290.cd-12-0095 · 2012 · External reference
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
10.1126/scisignal.2004088 · 2013 · External reference
Tissue-Based Map of the Human Proteome
10.1126/science.1260419 · 2015 · External reference
A Subcellular Map of the Human Proteome
10.1126/science.aal3321 · 2017 · External reference
CellMiner: A Web-Based Suite of Genomic and Pharmacologic Tools to Explore Transcript and Drug Patterns in the NCI-60 Cell Line Set
10.1158/0008-5472.can-12-1370 · 2012 · External reference
10.1186/1471-2164-10-277
10.1186/1471-2164-10-277 · External reference
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
10.1006/meth.2001.1262 · 2001 · External reference
10.3390/cells9071692
10.3390/cells9071692 · External reference
Peroxisomes and Cancer: The Role of a Metabolic Specialist in a Disease of Aberrant Metabolism
10.1016/j.bbcan.2018.07.004 · 2018 · External reference
Peroxisomal Metabolism and Oxidative Stress
10.1016/j.biochi.2013.07.026 · 2014 · External reference
A Highly Water-Soluble Disulfonated Tetrazolium Salt as a Chromogenic Indicator for NADH as Well as Cell Viability
10.1016/s0039-9140(97)00017-9 · 1997 · External reference
10.1186/s12885-026-16477-2
10.1186/s12885-026-16477-2 · External reference
NOP2-Regulated m5C Methylation of FKBP4 in Promoting Lung Adenocarcinoma Progression
10.1016/j.yexcr.2026.115129 · 2026 · External reference
Delineation of Human Prostate Cancer Evolution Identifies Chromothripsis as a Polyclonal Event and FKBP4 as a Potential Driver of Castration Resistance
10.1002/path.5052 · ExternalCitation · doi-reference
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
10.1006/meth.2001.1262 · ExternalCitation · doi-reference
Peroxisomes and Cancer: The Role of a Metabolic Specialist in a Disease of Aberrant Metabolism
10.1016/j.bbcan.2018.07.004 · ExternalCitation · doi-reference
Peroxisomal Metabolism and Oxidative Stress
10.1016/j.biochi.2013.07.026 · ExternalCitation · doi-reference
The Molecular Signatures Database (MSigDB) Hallmark Gene Set Collection
10.1016/j.cels.2015.12.004 · ExternalCitation · doi-reference
FKBP51 and FKBP52 in Signaling and Disease
10.1016/j.tem.2011.08.001 · ExternalCitation · doi-reference
NOP2-Regulated m5C Methylation of FKBP4 in Promoting Lung Adenocarcinoma Progression
10.1016/j.yexcr.2026.115129 · ExternalCitation · doi-reference
A Highly Water-Soluble Disulfonated Tetrazolium Salt as a Chromogenic Indicator for NADH as Well as Cell Viability
10.1016/s0039-9140(97)00017-9 · ExternalCitation · doi-reference
Lung Cancer
10.1016/s0140-6736(21)00312-3 · ExternalCitation · doi-reference
The Biology and Management of Non-Small Cell Lung Cancer
10.1038/nature25183 · ExternalCitation · doi-reference
Tumour Heterogeneity and Resistance to Cancer Therapies
10.1038/nrclinonc.2017.166 · ExternalCitation · doi-reference
The HSP90 Chaperone Machinery
10.1038/nrm.2017.20 · ExternalCitation · doi-reference
FKBP4 Integrates FKBP4/Hsp90/IKK with FKBP4/Hsp70/RelA Complex to Promote Lung Adenocarcinoma Progression via IKK/NF-κB Signaling
10.1038/s41419-021-03857-8 · ExternalCitation · doi-reference
Toward a Shared Vision for Cancer Genomic Data
10.1056/nejmp1607591 · ExternalCitation · doi-reference
Gene Set Enrichment Analysis: A Knowledge-Based Approach for Interpreting Genome-Wide Expression Profiles
10.1073/pnas.0506580102 · ExternalCitation · doi-reference
Targeting the Regulation of Androgen Receptor Signaling by the Heat Shock Protein 90 Cochaperone FKBP52 in Prostate Cancer Cells
10.1073/pnas.1105160108 · ExternalCitation · doi-reference
FK506-Binding Proteins 51 and 52 Differentially Regulate Dynein Interaction and Nuclear Translocation of the Glucocorticoid Receptor in Mammalian Cells
10.1074/jbc.m407498200 · ExternalCitation · doi-reference
TCGAbiolinks: An R/Bioconductor Package for Integrative Analysis of TCGA Data
10.1093/nar/gkv1507 · ExternalCitation · doi-reference
Tissue-Based Map of the Human Proteome
10.1126/science.1260419 · ExternalCitation · doi-reference
A Subcellular Map of the Human Proteome
10.1126/science.aal3321 · ExternalCitation · doi-reference
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
10.1126/scisignal.2004088 · ExternalCitation · doi-reference
CellMiner: A Web-Based Suite of Genomic and Pharmacologic Tools to Explore Transcript and Drug Patterns in the NCI-60 Cell Line Set
10.1158/0008-5472.can-12-1370 · ExternalCitation · doi-reference
The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data
10.1158/2159-8290.cd-12-0095 · ExternalCitation · doi-reference
10.1186/1471-2164-10-277
10.1186/1471-2164-10-277 · ExternalCitation · doi-reference
10.1186/s12885-026-16477-2
10.1186/s12885-026-16477-2 · ExternalCitation · doi-reference
10.3390/cells9071692
10.3390/cells9071692 · ExternalCitation · doi-reference
FKBP4 Connects mTORC2 and PI3K to Activate the PDK1/Akt-Dependent Cell Proliferation Signaling in Breast Cancer
10.7150/thno.35561 · ExternalCitation · doi-reference
