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References from Peripheral BDNF–TrkB Expression and Vitamin D Status in Depression, Prediabetes and Type 2 Diabetes: A Cross-Sectional Biomarker Study. Local targets link to admitted publications; unresolved targets remain external evidence.
10.3390/jcm13103006
10.3390/jcm13103006 · External reference
10.3390/psychiatryint6040125
10.3390/psychiatryint6040125 · External reference
10.1186/s12888-022-04494-x
10.1186/s12888-022-04494-x · External reference
The link between depression and diabetes: The search for shared mechanisms
10.1016/s2213-8587(15)00134-5 · 2015 · External reference
Factors influencing medication adherence in co-morbid hypertension and diabetes patients: A scoping review
2024 · External reference
10.3390/diabetology6050033
10.3390/diabetology6050033 · External reference
War, diet, and PTSD in Ukrainian youth
10.1038/s41598-025-31138-3 · 2025 · External reference
10.3390/nu18050819
10.3390/nu18050819 · External reference
The Psychiatric-Metabolic Interface: Exploring the Interplay Between Mental Disorders and Metabolic Syndrome
10.1155/mij/4208707 · 2026 · External reference
10.3389/fimmu.2024.1349883
10.3389/fimmu.2024.1349883 · External reference
Analysis of the transcriptional activity of genes of neuropeptides and their receptors in the blood of patients with thyroid pathology
10.25122/jml-2020-0183 · 2021 · External reference
Inflamed moods: A review of the interactions between inflammation and mood disorders
10.1016/j.pnpbp.2014.01.013 · 2014 · External reference
Nerve impulse transmission pathway-focused genes expression analysis in patients with primary hypothyroidism and autoimmune thyroiditis
10.2478/enr-2020-0013 · 2020 · External reference
Primary hypothyroidism and autoimmune thyroiditis alter the transcriptional activity of genes regulating neurogenesis in the blood of patients
10.2478/enr-2021-0002 · 2021 · External reference
10.3390/molecules30040848
10.3390/molecules30040848 · External reference
10.3390/ijms26178335
10.3390/ijms26178335 · External reference
Apoptosis and Cell Cycle Pathway-Focused Genes Expression Analysis in Patients with Different Forms of Thyroid Pathology
2020 · External reference
The brain-derived neurotrophic factor in neuronal plasticity and neuroregeneration: New pharmacological concepts for old and new drugs
10.4103/1673-5374.233438 · 2018 · External reference
BDNF: A Key Factor with Multipotent Impact on Brain Signaling and Synaptic Plasticity
10.1007/s10571-017-0510-4 · 2018 · External reference
Neuronal plasticity and neurotrophic factors in drug responses
10.1038/mp.2017.61 · 2017 · External reference
10.3390/biology13110907
10.3390/biology13110907 · External reference
10.3390/ijms23126827
10.3390/ijms23126827 · External reference
BDNF blood serum linkage with BDNF gene polymorphism (rs6265) in thyroid pathology patients in the West-Ukrainian population
10.2478/enr-2021-0021 · 2021 · External reference
Neurotrophin-regulated signalling pathways
2006 · External reference
10.3390/ijms19113650
10.3390/ijms19113650 · External reference
Brain-derived neurotrophic factor and neuropsychiatric disorders
10.1124/pr.111.005108 · 2012 · External reference
A neurotrophic model for stress-related mood disorders
10.1016/j.biopsych.2006.02.013 · 2006 · External reference
Stress, depression, and neuroplasticity: A convergence of mechanisms
10.1038/sj.npp.1301574 · 2008 · External reference
10.3390/ijms26073219
10.3390/ijms26073219 · External reference
10.3389/fendo.2024.1492741
10.3389/fendo.2024.1492741 · External reference
Decreased serum brain-derived neurotrophic factor levels in major depressed patients
10.1016/s0165-1781(02)00005-7 · 2002 · External reference
Serum brain-derived neurotrophic factor, depression, and antidepressant medications: Meta-analyses and implications
10.1016/j.biopsych.2008.05.005 · 2008 · External reference
Serum BDNF concentrations as peripheral manifestations of depression: Evidence from a systematic review and meta-analyses on 179 associations (N=9484)
10.1038/mp.2013.105 · 2014 · External reference
Brain-derived neurotrophic factor (BDNF) and type 2 diabetes
10.1007/s00125-006-0537-4 · 2007 · External reference
Neurotrophin presence in human coronary atherosclerosis and metabolic syndrome: A role for NGF and BDNF in cardiovascular disease?
10.1016/s0079-6123(03)46018-4 · 2004 · External reference
Serum brain-derived neurotrophic factor level is increased and associated with obesity in newly diagnosed female patients with type 2 diabetes mellitus
10.1016/j.metabol.2006.02.012 · 2006 · External reference
Brain-derived neurotrophic factor regulates glucose metabolism by modulating energy balance in diabetic mice
10.2337/diabetes.49.3.436 · 2000 · External reference
The Role of Vitamin D in Brain Health: A Mini Literature Review
2018 · External reference
Vitamin D: The crucial neuroprotective factor for nerve cells
10.1016/j.neuroscience.2024.09.042 · 2024 · External reference
10.3390/ijms26157146
10.3390/ijms26157146 · External reference
25-OH Vitamin D blood serum linkage with VDR gene polymorphism (rs2228570) in thyroid pathology patients in the West-Ukrainian population
10.25122/jml-2021-0101 · 2021 · External reference
Vitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease
10.1016/j.yfrne.2012.07.001 · 2013 · External reference
Vitamin D and Depression: Cellular and Regulatory Mechanisms
10.1124/pr.116.013227 · 2017 · External reference
Vitamin D as a neurosteroid affecting the developing and adult brain
10.1146/annurev-nutr-071813-105557 · 2014 · External reference
Vitamin D deficiency and depression in adults: Systematic review and meta-analysis
10.1192/bjp.bp.111.106666 · 2013 · External reference
Depression and Vitamin D Deficiency: Causality, Assessment, and Clinical Practice Implications
10.4172/neuropsychiatry.1000255 · 2017 · External reference
10.3390/ijms25147809
10.3390/ijms25147809 · External reference
The role of BDNF in major depressive disorder, related clinical features, and antidepressant treatment: Insight from meta-analyses
10.1016/j.neubiorev.2023.105159 · 2023 · External reference
A systematic review and meta-analysis of association between brain-derived neurotrophic factor and type 2 diabetes and glycemic profile
10.1038/s41598-021-93271-z · 2021 · External reference
The association between low vitamin D and depressive disorders
10.1038/mp.2013.36 · 2014 · External reference
Vitamin D deficiency and its associated factors among patients with type 2 diabetes mellitus: A systematic review and meta-analysis
10.1136/bmjopen-2023-075607 · 2023 · External reference
10.2337/dc25-s002
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10.3389/abp.2025.15459
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The new Roche Vitamin D Total assay: Fit for its purpose ?
10.1515/cclm-2011-0085 · 2012 · External reference
The PHQ-9: Validity of a brief depression severity measure
10.1046/j.1525-1497.2001.016009606.x · 2001 · External reference
10.1007/978-3-030-77644-2
10.1007/978-3-030-77644-2 · External reference
Generalized Anxiety Disorder 7-item (GAD-7) and 2-item (GAD-2) scales for detecting anxiety disorders in adults
2025 · External reference
10.1371/journal.pone.0261590
10.1371/journal.pone.0261590 · External reference
The WHO-5 Well-Being Index: A systematic review of the literature
10.1159/000376585 · 2015 · External reference
Systematic Review of the Use of the WHO-5 Well-Being Index Across Different Disease Areas
10.1007/s12325-025-03266-9 · 2025 · External reference
Assessment of diabetes-related distress
10.2337/diacare.18.6.754 · 1995 · External reference
Short-form measures of diabetes-related emotional distress: The Problem Areas in Diabetes Scale (PAID)-5 and PAID-1
10.1007/s00125-009-1559-5 · 2010 · External reference
Assessment of the type 2 diabetes risk using the Finnish Diabetes Risk Score questionnaire, and its predictors at the population level in Poland
2026 · External reference
The Finnish Diabetes Risk Score (FINDRISC), incident diabetes and low-grade inflammation
10.1016/j.diabres.2020.108558 · 2021 · External reference
The dominance analysis approach for comparing predictors in multiple regression
10.1037/1082-989x.8.2.129 · 2003 · External reference
Estimators of Relative Importance in Linear Regression Based on Variance Decomposition
10.1198/000313007x188252 · 2007 · External reference
Brain-derived neurotrophic factor in neurodegenerative diseases
10.1038/nrneurol.2009.54 · 2009 · External reference
The cytochrome 11B2 aldosterone synthase gene CYP11B2 (RS1799998) polymorphism associates with chronic kidney disease in hypertensive patients
10.33263/briac103.406411 · 2020 · External reference
Association between Serum Brain-derived Neurotrophic Factor and 25-OH Vitamin D Levels with Vitamin D Receptors Gene Polymorphism (rs2228570) in Patients with Autoimmune Thyroiditis and Hypothyroidism
2021 · External reference
10.3389/fnut.2025.1545443
10.3389/fnut.2025.1545443 · External reference
Brain-derived neurotrophic factor and inflammatory markers in patients with early- vs. late-stage bipolar disorder
10.1017/s1461145708009310 · 2009 · External reference
10.1186/s12916-015-0529-7
10.1186/s12916-015-0529-7 · External reference
10.3390/nu16162617
10.3390/nu16162617 · External reference
10.3390/brainsci15090928
10.3390/brainsci15090928 · External reference
10.3390/ijms26094271
10.3390/ijms26094271 · External reference
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10.1038/s41598-026-56817-7 · 2026 · External reference
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10.3390/jcm15041621
10.3390/jcm15041621 · External reference
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10.3389/fphar.2025.1565592 · External reference
The role of inflammation in depression: From evolutionary imperative to modern treatment target
10.1038/nri.2015.5 · 2016 · External reference
Eating ourselves to death (and despair): The contribution of adiposity and inflammation to depression
10.1016/j.pneurobio.2010.04.004 · 2010 · External reference
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10.1186/s12916-023-03001-7
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10.1186/s12889-021-11327-1 · External reference
The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments
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10.1007/978-3-030-77644-2
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Short-form measures of diabetes-related emotional distress: The Problem Areas in Diabetes Scale (PAID)-5 and PAID-1
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BDNF: A Key Factor with Multipotent Impact on Brain Signaling and Synaptic Plasticity
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Systematic Review of the Use of the WHO-5 Well-Being Index Across Different Disease Areas
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A neurotrophic model for stress-related mood disorders
10.1016/j.biopsych.2006.02.013 · ExternalCitation · doi-reference
Serum brain-derived neurotrophic factor, depression, and antidepressant medications: Meta-analyses and implications
10.1016/j.biopsych.2008.05.005 · ExternalCitation · doi-reference
The Finnish Diabetes Risk Score (FINDRISC), incident diabetes and low-grade inflammation
10.1016/j.diabres.2020.108558 · ExternalCitation · doi-reference
Serum brain-derived neurotrophic factor level is increased and associated with obesity in newly diagnosed female patients with type 2 diabetes mellitus
10.1016/j.metabol.2006.02.012 · ExternalCitation · doi-reference
The role of BDNF in major depressive disorder, related clinical features, and antidepressant treatment: Insight from meta-analyses
10.1016/j.neubiorev.2023.105159 · ExternalCitation · doi-reference
Vitamin D: The crucial neuroprotective factor for nerve cells
10.1016/j.neuroscience.2024.09.042 · ExternalCitation · doi-reference
Eating ourselves to death (and despair): The contribution of adiposity and inflammation to depression
10.1016/j.pneurobio.2010.04.004 · ExternalCitation · doi-reference
Inflamed moods: A review of the interactions between inflammation and mood disorders
10.1016/j.pnpbp.2014.01.013 · ExternalCitation · doi-reference
Vitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease
10.1016/j.yfrne.2012.07.001 · ExternalCitation · doi-reference
Neurotrophin presence in human coronary atherosclerosis and metabolic syndrome: A role for NGF and BDNF in cardiovascular disease?
10.1016/s0079-6123(03)46018-4 · ExternalCitation · doi-reference
Decreased serum brain-derived neurotrophic factor levels in major depressed patients
10.1016/s0165-1781(02)00005-7 · ExternalCitation · doi-reference
The link between depression and diabetes: The search for shared mechanisms
10.1016/s2213-8587(15)00134-5 · ExternalCitation · doi-reference
Brain-derived neurotrophic factor and inflammatory markers in patients with early- vs. late-stage bipolar disorder
10.1017/s1461145708009310 · ExternalCitation · doi-reference
The dominance analysis approach for comparing predictors in multiple regression
10.1037/1082-989x.8.2.129 · ExternalCitation · doi-reference
Serum BDNF concentrations as peripheral manifestations of depression: Evidence from a systematic review and meta-analyses on 179 associations (N=9484)
10.1038/mp.2013.105 · ExternalCitation · doi-reference
The association between low vitamin D and depressive disorders
10.1038/mp.2013.36 · ExternalCitation · doi-reference
Neuronal plasticity and neurotrophic factors in drug responses
10.1038/mp.2017.61 · ExternalCitation · doi-reference
The role of inflammation in depression: From evolutionary imperative to modern treatment target
10.1038/nri.2015.5 · ExternalCitation · doi-reference
Brain-derived neurotrophic factor in neurodegenerative diseases
10.1038/nrneurol.2009.54 · ExternalCitation · doi-reference
Diet and depression: Exploring the biological mechanisms of action
10.1038/s41380-020-00925-x · ExternalCitation · doi-reference
Diabetic neuropathy: Cutting-edge research and future directions
10.1038/s41392-025-02175-1 · ExternalCitation · doi-reference
A systematic review and meta-analysis of association between brain-derived neurotrophic factor and type 2 diabetes and glycemic profile
10.1038/s41598-021-93271-z · ExternalCitation · doi-reference
War, diet, and PTSD in Ukrainian youth
10.1038/s41598-025-31138-3 · ExternalCitation · doi-reference
Exercise-associated changes in leptin and irisin relate to cognitive function in older adults stratified by cognitive impairment
10.1038/s41598-026-56817-7 · ExternalCitation · doi-reference
Stress, depression, and neuroplasticity: A convergence of mechanisms
10.1038/sj.npp.1301574 · ExternalCitation · doi-reference
The PHQ-9: Validity of a brief depression severity measure
10.1046/j.1525-1497.2001.016009606.x · ExternalCitation · doi-reference
Brain-derived neurotrophic factor and neuropsychiatric disorders
10.1124/pr.111.005108 · ExternalCitation · doi-reference
Vitamin D and Depression: Cellular and Regulatory Mechanisms
10.1124/pr.116.013227 · ExternalCitation · doi-reference
Vitamin D deficiency and its associated factors among patients with type 2 diabetes mellitus: A systematic review and meta-analysis
10.1136/bmjopen-2023-075607 · ExternalCitation · doi-reference
Vitamin D as a neurosteroid affecting the developing and adult brain
10.1146/annurev-nutr-071813-105557 · ExternalCitation · doi-reference
The Psychiatric-Metabolic Interface: Exploring the Interplay Between Mental Disorders and Metabolic Syndrome
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The WHO-5 Well-Being Index: A systematic review of the literature
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Vitamin D deficiency and depression in adults: Systematic review and meta-analysis
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Estimators of Relative Importance in Linear Regression Based on Variance Decomposition
10.1198/000313007x188252 · ExternalCitation · doi-reference
10.1371/journal.pone.0261590
10.1371/journal.pone.0261590 · ExternalCitation · doi-reference
The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments
10.1373/clinchem.2008.112797 · ExternalCitation · doi-reference
The new Roche Vitamin D Total assay: Fit for its purpose ?
10.1515/cclm-2011-0085 · ExternalCitation · doi-reference
10.2337/dc25-s002
10.2337/dc25-s002 · ExternalCitation · doi-reference
Brain-derived neurotrophic factor regulates glucose metabolism by modulating energy balance in diabetic mice
10.2337/diabetes.49.3.436 · ExternalCitation · doi-reference
Assessment of diabetes-related distress
10.2337/diacare.18.6.754 · ExternalCitation · doi-reference
Nerve impulse transmission pathway-focused genes expression analysis in patients with primary hypothyroidism and autoimmune thyroiditis
10.2478/enr-2020-0013 · ExternalCitation · doi-reference
Primary hypothyroidism and autoimmune thyroiditis alter the transcriptional activity of genes regulating neurogenesis in the blood of patients
10.2478/enr-2021-0002 · ExternalCitation · doi-reference
BDNF blood serum linkage with BDNF gene polymorphism (rs6265) in thyroid pathology patients in the West-Ukrainian population
10.2478/enr-2021-0021 · ExternalCitation · doi-reference
Analysis of the transcriptional activity of genes of neuropeptides and their receptors in the blood of patients with thyroid pathology
10.25122/jml-2020-0183 · ExternalCitation · doi-reference
25-OH Vitamin D blood serum linkage with VDR gene polymorphism (rs2228570) in thyroid pathology patients in the West-Ukrainian population
10.25122/jml-2021-0101 · ExternalCitation · doi-reference
The cytochrome 11B2 aldosterone synthase gene CYP11B2 (RS1799998) polymorphism associates with chronic kidney disease in hypertensive patients
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Depression and Vitamin D Deficiency: Causality, Assessment, and Clinical Practice Implications
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