Research graph
References from Broad-Coverage Lipidomics Reveals Temporal Lipid Remodeling and Candidate Serum Biomarkers After Acute Spinal Cord Injury in Rats. Local targets link to admitted publications; unresolved targets remain external evidence.
Traumatic spinal cord injury
10.1038/nrdp.2017.18 · 2017 · External reference
Time is spine: A review of translational advances in spinal cord injury
10.3171/2018.9.spine18682 · 2019 · External reference
A Clinical Practice Guideline for the Management of Acute Spinal Cord Injury: Introduction, Rationale, and Scope
10.1177/2192568217703387 · 2017 · External reference
Inflammatory and structural biomarkers in acute traumatic spinal cord injury
10.1515/cclm.2011.068 · 2011 · External reference
Neurochemical biomarkers in spinal cord injury
10.1038/s41393-019-0319-8 · 2019 · External reference
Serum neurofilament light chain is a biomarker of human spinal cord injury severity and outcome
10.1136/jnnp-2013-307454 · 2015 · External reference
Global burden of traumatic brain and spinal cord injury
10.1016/s1474-4422(18)30444-7 · 2019 · External reference
Mitochondrial dysfunction as a target in spinal cord injury: Intimate correlation between pathological processes and therapeutic approaches
10.4103/1673-5374.369094 · 2023 · External reference
Mitochondrial regulatory mechanisms in spinal cord injury: A narrative review
10.1097/md.0000000000031930 · 2022 · External reference
10.3390/cells10051078
10.3390/cells10051078 · External reference
10.3390/ijms26146864
10.3390/ijms26146864 · External reference
Parallel Metabolomic Profiling of Cerebrospinal Fluid and Serum for Identifying Biomarkers of Injury Severity after Acute Human Spinal Cord Injury
10.1038/srep38718 · 2016 · External reference
Lysophospholipids Are Associated With Outcomes in Hospitalized Patients With Mild Traumatic Brain Injury
10.1089/neu.2023.0046 · 2024 · External reference
Evolution of Lipid Metabolism in the Injured Mouse Spinal Cord
10.1089/neu.2024.0385 · 2025 · External reference
The foundations and development of lipidomics
10.1016/j.jlr.2021.100164 · 2022 · External reference
10.1101/2023.06.05.543746
10.1101/2023.06.05.543746 · External reference
Integrated multi-omics analysis reveals molecular changes associated with chronic lipid accumulation following contusive spinal cord injury
10.1016/j.expneurol.2024.114909 · 2024 · External reference
Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection
10.1006/exnr.1996.0098 · 1996 · External reference
10.1089/neu.1992.9.123
10.1089/neu.1992.9.123 · External reference
10.3389/fnins.2022.838786
10.3389/fnins.2022.838786 · External reference
Systemic inflammation after spinal cord injury: A review of biological evidence, related health risks, and potential therapies
10.1016/j.coph.2022.102303 · 2022 · External reference
Risk factors for in-hospital mortality in cervical spinal cord injuries: A nationwide, cross-sectional analysis of concomitant injuries, comorbidities, and treatment strategies in 3847 cases
10.1016/j.spinee.2025.05.004 · 2025 · External reference
Association of CSF and Serum Neurofilament Light and Glial Fibrillary Acidic Protein, Injury Severity, and Outcome in Spinal Cord Injury
10.1212/wnl.0000000000206744 · 2023 · External reference
Application value of biofluid-based biomarkers for the diagnosis and treatment of spinal cord injury
10.4103/1673-5374.324823 · 2022 · External reference
10.3390/diagnostics13101814
10.3390/diagnostics13101814 · External reference
10.3389/fnins.2022.1066528
10.3389/fnins.2022.1066528 · External reference
Single-cell and spatial atlases of spinal cord injury in the Tabulae Paralytica
10.1038/s41586-024-07504-y · 2024 · External reference
Single cell atlas of spinal cord injury in mice reveals a pro-regenerative signature in spinocerebellar neurons
10.1038/s41467-022-33184-1 · 2022 · External reference
Single-cell analysis reveals region-heterogeneous responses in rhesus monkey spinal cord with complete injury
10.1038/s41467-023-40513-5 · 2023 · External reference
Lipid accumulation in foam cells drives C1q-dependent synaptic loss and impairs motor function recovery after spinal cord injury
10.1038/s42003-025-09167-5 · 2025 · External reference
Per2 deficiency in microglia alleviates motor dysfunction by inhibiting ferroptosis in spinal cord injury
10.1038/s42003-025-08664-x · 2025 · External reference
Treg-microglia partnership in the injured spinal cord preserves Treg cell function and regulates microglial cholesterol metabolism
10.1016/j.neuron.2025.09.001 · 2025 · External reference
Single-cell analysis of the cellular heterogeneity and interactions in the injured mouse spinal cord
10.1084/jem.20210040 · 2021 · External reference
Temporal and spatial cellular and molecular pathological alterations with single-cell resolution in the adult spinal cord after injury
10.1038/s41392-022-00885-4 · 2022 · External reference
The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3
10.1038/s41467-021-27244-1 · 2021 · External reference
10.3389/fphys.2021.732319
10.3389/fphys.2021.732319 · External reference
Secretory phospholipase A2-IIA targets bacterial extracellular vesicles to modulate immune signaling
10.1038/s42003-025-09025-4 · 2025 · External reference
Lesion-remote astrocytes govern microglia-mediated white matter repair
10.1038/s41586-025-09887-y · 2026 · External reference
Parallel Metabolomic Profiling of Cerebrospinal Fluid, Plasma, and Spinal Cord to Identify Biomarkers for Spinal Cord Injury
10.1007/s12031-021-01903-w · 2022 · External reference
Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials
10.1124/pharmrev.121.000408 · 2022 · External reference
Murine deficiency of peroxisomal L-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis
10.1007/s00018-021-03869-9 · 2021 · External reference
10.3390/metabo11010051
10.3390/metabo11010051 · External reference
Targeting long-chain acylcarnitine accumulation to protect cardiac mitochondrial homeostasis after complete revascularization
10.1016/j.xcrm.2025.102507 · 2025 · External reference
10.3390/nu15102392
10.3390/nu15102392 · External reference
10.3390/jcm11030627
10.3390/jcm11030627 · External reference
Diagnostic Performance of GFAP, UCH-L1, and MAP-2 Within 30 and 60 Minutes of Traumatic Brain Injury
10.1001/jamanetworkopen.2024.31115 · 2024 · External reference
Regulation of cholesterol homeostasis in health and diseases: From mechanisms to targeted therapeutics
10.1038/s41392-022-01125-5 · 2022 · External reference
Structure-based mechanism and inhibition of cholesteryl ester transfer protein
10.1007/s11883-023-01087-1 · 2023 · External reference
Regulating PPARG Reduces Lipid Accumulation in Microglia and Promotes Functional Recovery After Spinal Cord Injury
10.1002/advs.202506313 · 2025 · External reference
Unresolved Excess Accumulation of Myelin-Derived Cholesterol Contributes to Scar Formation after Spinal Cord Injury
10.34133/research.0135 · 2023 · External reference
Cholesterol in the CNS: Functions, recycling and remyelination
10.1186/s12974-025-03490-8 · 2025 · External reference
10.3390/ijms22168969
10.3390/ijms22168969 · External reference
Spinal cord injury models: Advantages and disadvantages in the view of pathophysiology and clinical significance
2025 · External reference
10.3390/ijms25158285
10.3390/ijms25158285 · External reference
VLDL lipidomics reveals hepatocellular lipidome changes in metabolic dysfunction-associated steatotic liver disease
2025 · External reference
Diagnostic Performance of GFAP, UCH-L1, and MAP-2 Within 30 and 60 Minutes of Traumatic Brain Injury
10.1001/jamanetworkopen.2024.31115 · ExternalCitation · doi-reference
Regulating PPARG Reduces Lipid Accumulation in Microglia and Promotes Functional Recovery After Spinal Cord Injury
10.1002/advs.202506313 · ExternalCitation · doi-reference
Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection
10.1006/exnr.1996.0098 · ExternalCitation · doi-reference
Murine deficiency of peroxisomal L-bifunctional protein (EHHADH) causes medium-chain 3-hydroxydicarboxylic aciduria and perturbs hepatic cholesterol homeostasis
10.1007/s00018-021-03869-9 · ExternalCitation · doi-reference
Structure-based mechanism and inhibition of cholesteryl ester transfer protein
10.1007/s11883-023-01087-1 · ExternalCitation · doi-reference
Parallel Metabolomic Profiling of Cerebrospinal Fluid, Plasma, and Spinal Cord to Identify Biomarkers for Spinal Cord Injury
10.1007/s12031-021-01903-w · ExternalCitation · doi-reference
Systemic inflammation after spinal cord injury: A review of biological evidence, related health risks, and potential therapies
10.1016/j.coph.2022.102303 · ExternalCitation · doi-reference
Integrated multi-omics analysis reveals molecular changes associated with chronic lipid accumulation following contusive spinal cord injury
10.1016/j.expneurol.2024.114909 · ExternalCitation · doi-reference
The foundations and development of lipidomics
10.1016/j.jlr.2021.100164 · ExternalCitation · doi-reference
Treg-microglia partnership in the injured spinal cord preserves Treg cell function and regulates microglial cholesterol metabolism
10.1016/j.neuron.2025.09.001 · ExternalCitation · doi-reference
Risk factors for in-hospital mortality in cervical spinal cord injuries: A nationwide, cross-sectional analysis of concomitant injuries, comorbidities, and treatment strategies in 3847 cases
10.1016/j.spinee.2025.05.004 · ExternalCitation · doi-reference
Targeting long-chain acylcarnitine accumulation to protect cardiac mitochondrial homeostasis after complete revascularization
10.1016/j.xcrm.2025.102507 · ExternalCitation · doi-reference
Global burden of traumatic brain and spinal cord injury
10.1016/s1474-4422(18)30444-7 · ExternalCitation · doi-reference
Traumatic spinal cord injury
10.1038/nrdp.2017.18 · ExternalCitation · doi-reference
Temporal and spatial cellular and molecular pathological alterations with single-cell resolution in the adult spinal cord after injury
10.1038/s41392-022-00885-4 · ExternalCitation · doi-reference
Regulation of cholesterol homeostasis in health and diseases: From mechanisms to targeted therapeutics
10.1038/s41392-022-01125-5 · ExternalCitation · doi-reference
Neurochemical biomarkers in spinal cord injury
10.1038/s41393-019-0319-8 · ExternalCitation · doi-reference
The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3
10.1038/s41467-021-27244-1 · ExternalCitation · doi-reference
Single cell atlas of spinal cord injury in mice reveals a pro-regenerative signature in spinocerebellar neurons
10.1038/s41467-022-33184-1 · ExternalCitation · doi-reference
Single-cell analysis reveals region-heterogeneous responses in rhesus monkey spinal cord with complete injury
10.1038/s41467-023-40513-5 · ExternalCitation · doi-reference
Single-cell and spatial atlases of spinal cord injury in the Tabulae Paralytica
10.1038/s41586-024-07504-y · ExternalCitation · doi-reference
Lesion-remote astrocytes govern microglia-mediated white matter repair
10.1038/s41586-025-09887-y · ExternalCitation · doi-reference
Per2 deficiency in microglia alleviates motor dysfunction by inhibiting ferroptosis in spinal cord injury
10.1038/s42003-025-08664-x · ExternalCitation · doi-reference
Secretory phospholipase A2-IIA targets bacterial extracellular vesicles to modulate immune signaling
10.1038/s42003-025-09025-4 · ExternalCitation · doi-reference
Lipid accumulation in foam cells drives C1q-dependent synaptic loss and impairs motor function recovery after spinal cord injury
10.1038/s42003-025-09167-5 · ExternalCitation · doi-reference
Parallel Metabolomic Profiling of Cerebrospinal Fluid and Serum for Identifying Biomarkers of Injury Severity after Acute Human Spinal Cord Injury
10.1038/srep38718 · ExternalCitation · doi-reference
Single-cell analysis of the cellular heterogeneity and interactions in the injured mouse spinal cord
10.1084/jem.20210040 · ExternalCitation · doi-reference
10.1089/neu.1992.9.123
10.1089/neu.1992.9.123 · ExternalCitation · doi-reference
Lysophospholipids Are Associated With Outcomes in Hospitalized Patients With Mild Traumatic Brain Injury
10.1089/neu.2023.0046 · ExternalCitation · doi-reference
Evolution of Lipid Metabolism in the Injured Mouse Spinal Cord
10.1089/neu.2024.0385 · ExternalCitation · doi-reference
Mitochondrial regulatory mechanisms in spinal cord injury: A narrative review
10.1097/md.0000000000031930 · ExternalCitation · doi-reference
10.1101/2023.06.05.543746
10.1101/2023.06.05.543746 · ExternalCitation · doi-reference
Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials
10.1124/pharmrev.121.000408 · ExternalCitation · doi-reference
Serum neurofilament light chain is a biomarker of human spinal cord injury severity and outcome
10.1136/jnnp-2013-307454 · ExternalCitation · doi-reference
A Clinical Practice Guideline for the Management of Acute Spinal Cord Injury: Introduction, Rationale, and Scope
10.1177/2192568217703387 · ExternalCitation · doi-reference
Cholesterol in the CNS: Functions, recycling and remyelination
10.1186/s12974-025-03490-8 · ExternalCitation · doi-reference
Association of CSF and Serum Neurofilament Light and Glial Fibrillary Acidic Protein, Injury Severity, and Outcome in Spinal Cord Injury
10.1212/wnl.0000000000206744 · ExternalCitation · doi-reference
Inflammatory and structural biomarkers in acute traumatic spinal cord injury
10.1515/cclm.2011.068 · ExternalCitation · doi-reference
Time is spine: A review of translational advances in spinal cord injury
10.3171/2018.9.spine18682 · ExternalCitation · doi-reference
10.3389/fnins.2022.1066528
10.3389/fnins.2022.1066528 · ExternalCitation · doi-reference
10.3389/fnins.2022.838786
10.3389/fnins.2022.838786 · ExternalCitation · doi-reference
10.3389/fphys.2021.732319
10.3389/fphys.2021.732319 · ExternalCitation · doi-reference
10.3390/cells10051078
10.3390/cells10051078 · ExternalCitation · doi-reference
10.3390/diagnostics13101814
10.3390/diagnostics13101814 · ExternalCitation · doi-reference
10.3390/ijms22168969
10.3390/ijms22168969 · ExternalCitation · doi-reference
10.3390/ijms25158285
10.3390/ijms25158285 · ExternalCitation · doi-reference
10.3390/ijms26146864
10.3390/ijms26146864 · ExternalCitation · doi-reference
10.3390/jcm11030627
10.3390/jcm11030627 · ExternalCitation · doi-reference
10.3390/metabo11010051
10.3390/metabo11010051 · ExternalCitation · doi-reference
10.3390/nu15102392
10.3390/nu15102392 · ExternalCitation · doi-reference
Unresolved Excess Accumulation of Myelin-Derived Cholesterol Contributes to Scar Formation after Spinal Cord Injury
10.34133/research.0135 · ExternalCitation · doi-reference
Application value of biofluid-based biomarkers for the diagnosis and treatment of spinal cord injury
10.4103/1673-5374.324823 · ExternalCitation · doi-reference
Mitochondrial dysfunction as a target in spinal cord injury: Intimate correlation between pathological processes and therapeutic approaches
10.4103/1673-5374.369094 · ExternalCitation · doi-reference
