Research graph
References from Circulating Tumor DNA (ctDNA) Clearance After Immune Checkpoint Inhibition (ICI) with Radiotherapy (RT) as a Prognostic Biomarker for Advanced Melanoma. Local targets link to admitted publications; unresolved targets remain external evidence.
Cancer statistics, 2026
2026 · External reference
Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in Advanced Melanoma
10.1056/nejmoa2407417 · 2025 · External reference
Melanoma Treatments and Mortality Rate Trends in the US, 1975 to 2019
10.1001/jamanetworkopen.2022.45269 · 2022 · External reference
Pembrolizumab versus ipilimumab for advanced melanoma: 10-year follow-up of the phase III KEYNOTE-006 study
10.1016/j.annonc.2024.08.2330 · 2024 · External reference
Relatlimab and Nivolumab versus Nivolumab in Untreated Advanced Melanoma
10.1056/nejmoa2109970 · 2022 · External reference
Cutaneous melanoma
10.1016/s0140-6736(23)00821-8 · 2023 · External reference
Re-examining the role of adjuvant radiation therapy
10.1002/jso.25329 · 2019 · External reference
Radiation and Melanoma: Where Are We Now?
10.1007/s11912-024-01557-y · 2024 · External reference
Long-Term Survival in Patients With Advanced Melanoma
10.1001/jamanetworkopen.2024.26641 · 2024 · External reference
10.3390/cancers16050854
10.3390/cancers16050854 · External reference
Multi-Institutional Study Evaluating the Role of Early Circulating Tumor DNA Dynamics During Treatment With Immune Checkpoint Inhibitors in Patients With Advanced-Stage Melanoma
10.1200/po-25-00254 · 2026 · External reference
Circulating tumor DNA-based molecular residual disease detection for treatment monitoring in advanced melanoma patients
10.1002/cncr.34716 · 2023 · External reference
CtDNA Dynamics Identifies Pseudoprogression in a Metastatic Melanoma Patient Treated With Nivolumab/Relatlimab
10.1097/cji.0000000000000569 · 2025 · External reference
Association Between Circulating Tumor DNA and Pseudoprogression in Patients With Metastatic Melanoma Treated With Anti-Programmed Cell Death 1 Antibodies
10.1001/jamaoncol.2017.5332 · 2018 · External reference
Circulating tumour DNA (ctDNA) in metastatic melanoma, a systematic review and meta-analysis
10.1016/j.ejca.2021.09.019 · 2021 · External reference
Circulating tumour DNA and melanoma survival: A systematic literature review and meta-analysis
10.1016/j.critrevonc.2020.103187 · 2021 · External reference
The role of circulating tumor DNA in the management of melanoma: A literature review
10.1097/cmr.0000000000001117 · 2026 · External reference
10.3389/fimmu.2024.1520441
10.3389/fimmu.2024.1520441 · External reference
NetAUC: A network-based multi-biomarker identification method by AUC optimization
10.1016/j.ymeth.2021.08.001 · 2022 · External reference
FUNMarker: Fusion Network-Based Method to Identify Prognostic and Heterogeneous Breast Cancer Biomarkers
10.1109/tcbb.2020.2973148 · 2021 · External reference
Immunotherapy and radiotherapy in melanoma: A multidisciplinary comprehensive review
10.1080/21645515.2021.1903827 · 2022 · External reference
Radiotherapy, immunity, and immune checkpoint inhibitors
10.1016/s1470-2045(24)00075-5 · 2024 · External reference
Radiotherapy and immunotherapy in cancer treatment: Mechanisms of clinical synergy
10.1172/jci207550 · 2026 · External reference
Inflammatory microenvironment remodelling by tumour cells after radiotherapy
10.1038/s41568-020-0246-1 · 2020 · External reference
Radiotherapy increases plasma levels of tumoral cell-free DNA in non-small cell lung cancer patients
10.18632/oncotarget.25053 · 2018 · External reference
Quantification of circulating cell-free DNA in the plasma of cancer patients during radiation therapy
10.1111/j.1349-7006.2008.01021.x · 2009 · External reference
Release of Cell-Free Tumor DNA in the Plasma of Uveal Melanoma Patients Under Radiotherapy
2023 · External reference
Abscopal effects in patients with malignant melanoma treated with radiotherapy and immune checkpoint inhibition: Analysis of a large observational multicenter study
10.1136/jitc-2025-012717 · 2025 · External reference
Radiotherapy-induced abscopal effects in immune checkpoint inhibitor-refractory metastatic disease: Results from a large multicenter real-world cohort study
10.1080/2162402x.2025.2610529 · 2026 · External reference
Radiotherapy with or without immunotherapy in metastatic melanoma: Efficacy and tolerability
10.1080/0284186x.2023.2280766 · 2023 · External reference
10.3390/cancers14174213
10.3390/cancers14174213 · External reference
Arsenic trioxide-based nanoparticles for enhanced chemotherapy by activating pyroptosis
10.1016/j.apsb.2025.08.003 · 2025 · External reference
CHB patients with rtA181T-mutated HBV infection are associated with higher risk hepatocellular carcinoma due to increases in mutation rates of tumour suppressor genes
10.1111/jvh.13886 · 2023 · External reference
Identification of cuproptosis-related lncRNAs with the significance in prognosis and immunotherapy of oral squamous cell carcinoma
10.1016/j.compbiomed.2024.108198 · 2024 · External reference
5-HT reuptake blockade induces pyroptosis in BRAFV600E-mutated melanomas via remodeling histone serotonylation
10.1016/j.xcrm.2025.102537 · 2026 · External reference
10.3389/fimmu.2025.1689103
10.3389/fimmu.2025.1689103 · External reference
Clinical characteristics, treatment, and outcomes of nivolumab induced immune thrombocytopenia
10.1007/s10637-024-01472-w · 2024 · External reference
Simultaneous quantification of mirabegron and vibegron in human plasma by HPLC-MS/MS and its application in the clinical determination in patients with tumors associated with overactive bladder
10.1016/j.jpba.2023.115937 · 2024 · External reference
Sensitivity of Circulating Tumor DNA for Detection of Minimal Residual Disease Recurrence or Relapse in Patients with Melanoma
10.1200/oa-25-00119 · 2026 · External reference
Panoramic hybrid transmission topology and spatially adaptive sensitivity compensation EIT: Wide-field deep imaging via dual-array
10.1063/5.0320664 · 2026 · External reference
Melanoma Treatments and Mortality Rate Trends in the US, 1975 to 2019
10.1001/jamanetworkopen.2022.45269 · ExternalCitation · doi-reference
Long-Term Survival in Patients With Advanced Melanoma
10.1001/jamanetworkopen.2024.26641 · ExternalCitation · doi-reference
Association Between Circulating Tumor DNA and Pseudoprogression in Patients With Metastatic Melanoma Treated With Anti-Programmed Cell Death 1 Antibodies
10.1001/jamaoncol.2017.5332 · ExternalCitation · doi-reference
Circulating tumor DNA-based molecular residual disease detection for treatment monitoring in advanced melanoma patients
10.1002/cncr.34716 · ExternalCitation · doi-reference
Re-examining the role of adjuvant radiation therapy
10.1002/jso.25329 · ExternalCitation · doi-reference
Clinical characteristics, treatment, and outcomes of nivolumab induced immune thrombocytopenia
10.1007/s10637-024-01472-w · ExternalCitation · doi-reference
Radiation and Melanoma: Where Are We Now?
10.1007/s11912-024-01557-y · ExternalCitation · doi-reference
Pembrolizumab versus ipilimumab for advanced melanoma: 10-year follow-up of the phase III KEYNOTE-006 study
10.1016/j.annonc.2024.08.2330 · ExternalCitation · doi-reference
Arsenic trioxide-based nanoparticles for enhanced chemotherapy by activating pyroptosis
10.1016/j.apsb.2025.08.003 · ExternalCitation · doi-reference
Identification of cuproptosis-related lncRNAs with the significance in prognosis and immunotherapy of oral squamous cell carcinoma
10.1016/j.compbiomed.2024.108198 · ExternalCitation · doi-reference
Circulating tumour DNA and melanoma survival: A systematic literature review and meta-analysis
10.1016/j.critrevonc.2020.103187 · ExternalCitation · doi-reference
Circulating tumour DNA (ctDNA) in metastatic melanoma, a systematic review and meta-analysis
10.1016/j.ejca.2021.09.019 · ExternalCitation · doi-reference
Simultaneous quantification of mirabegron and vibegron in human plasma by HPLC-MS/MS and its application in the clinical determination in patients with tumors associated with overactive bladder
10.1016/j.jpba.2023.115937 · ExternalCitation · doi-reference
5-HT reuptake blockade induces pyroptosis in BRAFV600E-mutated melanomas via remodeling histone serotonylation
10.1016/j.xcrm.2025.102537 · ExternalCitation · doi-reference
NetAUC: A network-based multi-biomarker identification method by AUC optimization
10.1016/j.ymeth.2021.08.001 · ExternalCitation · doi-reference
Cutaneous melanoma
10.1016/s0140-6736(23)00821-8 · ExternalCitation · doi-reference
Radiotherapy, immunity, and immune checkpoint inhibitors
10.1016/s1470-2045(24)00075-5 · ExternalCitation · doi-reference
Inflammatory microenvironment remodelling by tumour cells after radiotherapy
10.1038/s41568-020-0246-1 · ExternalCitation · doi-reference
Relatlimab and Nivolumab versus Nivolumab in Untreated Advanced Melanoma
10.1056/nejmoa2109970 · ExternalCitation · doi-reference
Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in Advanced Melanoma
10.1056/nejmoa2407417 · ExternalCitation · doi-reference
Panoramic hybrid transmission topology and spatially adaptive sensitivity compensation EIT: Wide-field deep imaging via dual-array
10.1063/5.0320664 · ExternalCitation · doi-reference
Radiotherapy with or without immunotherapy in metastatic melanoma: Efficacy and tolerability
10.1080/0284186x.2023.2280766 · ExternalCitation · doi-reference
Radiotherapy-induced abscopal effects in immune checkpoint inhibitor-refractory metastatic disease: Results from a large multicenter real-world cohort study
10.1080/2162402x.2025.2610529 · ExternalCitation · doi-reference
Immunotherapy and radiotherapy in melanoma: A multidisciplinary comprehensive review
10.1080/21645515.2021.1903827 · ExternalCitation · doi-reference
CtDNA Dynamics Identifies Pseudoprogression in a Metastatic Melanoma Patient Treated With Nivolumab/Relatlimab
10.1097/cji.0000000000000569 · ExternalCitation · doi-reference
The role of circulating tumor DNA in the management of melanoma: A literature review
10.1097/cmr.0000000000001117 · ExternalCitation · doi-reference
FUNMarker: Fusion Network-Based Method to Identify Prognostic and Heterogeneous Breast Cancer Biomarkers
10.1109/tcbb.2020.2973148 · ExternalCitation · doi-reference
Quantification of circulating cell-free DNA in the plasma of cancer patients during radiation therapy
10.1111/j.1349-7006.2008.01021.x · ExternalCitation · doi-reference
CHB patients with rtA181T-mutated HBV infection are associated with higher risk hepatocellular carcinoma due to increases in mutation rates of tumour suppressor genes
10.1111/jvh.13886 · ExternalCitation · doi-reference
Abscopal effects in patients with malignant melanoma treated with radiotherapy and immune checkpoint inhibition: Analysis of a large observational multicenter study
10.1136/jitc-2025-012717 · ExternalCitation · doi-reference
Radiotherapy and immunotherapy in cancer treatment: Mechanisms of clinical synergy
10.1172/jci207550 · ExternalCitation · doi-reference
Sensitivity of Circulating Tumor DNA for Detection of Minimal Residual Disease Recurrence or Relapse in Patients with Melanoma
10.1200/oa-25-00119 · ExternalCitation · doi-reference
Multi-Institutional Study Evaluating the Role of Early Circulating Tumor DNA Dynamics During Treatment With Immune Checkpoint Inhibitors in Patients With Advanced-Stage Melanoma
10.1200/po-25-00254 · ExternalCitation · doi-reference
Radiotherapy increases plasma levels of tumoral cell-free DNA in non-small cell lung cancer patients
10.18632/oncotarget.25053 · ExternalCitation · doi-reference
10.3389/fimmu.2024.1520441
10.3389/fimmu.2024.1520441 · ExternalCitation · doi-reference
10.3389/fimmu.2025.1689103
10.3389/fimmu.2025.1689103 · ExternalCitation · doi-reference
10.3390/cancers14174213
10.3390/cancers14174213 · ExternalCitation · doi-reference
10.3390/cancers16050854
10.3390/cancers16050854 · ExternalCitation · doi-reference