References

Engineered Extracellular Vesicles for Cancer Therapy

10.1002/adma.202005709 · ExternalCitation · doi-reference

Ipragliflozin Improves the Hepatic Outcomes of Patients with Diabetes with NAFLD

10.1002/hep4.1696 · ExternalCitation · doi-reference

Postdiagnosis body fatness, recreational physical activity, dietary factors and breast cancer prognosis: Global Cancer Update Programme (CUP Global) summary of evidence grading

10.1002/ijc.34320 · ExternalCitation · doi-reference

Postdiagnosis body fatness, weight change and breast cancer prognosis: Global Cancer Update Program (CUP global) systematic literature review and meta-analysis

10.1002/ijc.34322 · ExternalCitation · doi-reference

Emerging roles of exosomal miRNAs in breast cancer drug resistance

10.1002/iub.2116 · ExternalCitation · doi-reference

Influence of plasma circulating exosomes obtained from obese women on tumorigenesis and tamoxifen resistance in MCF-7 cells

10.1002/iub.2305 · ExternalCitation · doi-reference

Leptin signaling in breast cancer: An overview

10.1002/jcb.21911 · ExternalCitation · doi-reference

Standardizing analysis of circulating microRNA: Clinical and biological relevance

10.1002/jcb.24745 · ExternalCitation · doi-reference

An overview of microRNAs: Biology, functions, therapeutics, and analysis methods

10.1002/jcp.27486 · ExternalCitation · doi-reference

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

10.1002/jev2.12404 · ExternalCitation · doi-reference

Biogenesis, characterization, and functions of mirtrons

10.1002/wrna.1680 · ExternalCitation · doi-reference

The impact of obesity on adipocyte-derived extracellular vesicles

10.1007/s00018-021-03973-w · ExternalCitation · doi-reference

Exosomal miR-221/222 enhances tamoxifen resistance in recipient ER-positive breast cancer cells

10.1007/s10549-014-3037-0 · ExternalCitation · doi-reference

Association between germline single nucleotide polymorphisms in the PI3K-AKT-mTOR pathway, obesity, and breast cancer disease-free survival

10.1007/s10549-014-3081-9 · ExternalCitation · doi-reference

Metastatic breast cancer: The potential of miRNA for diagnosis and treatment monitoring

10.1007/s10555-015-9551-7 · ExternalCitation · doi-reference

Breast cancer microenvironment and obesity: Challenges for therapy

10.1007/s10555-022-10031-9 · ExternalCitation · doi-reference

The obesity-breast cancer link: A multidisciplinary perspective

10.1007/s10555-022-10043-5 · ExternalCitation · doi-reference

Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors

10.1007/s10637-016-0407-y · ExternalCitation · doi-reference

Adipokines: Deciphering the cardiovascular signature of adipose tissue

10.1016/j.bcp.2022.115324 · ExternalCitation · doi-reference

Hydroelectric actuator for 3-dimensional analysis of electrophoretic and dielectrophoretic behavior of cancer cells; suitable in diagnosis and invasion studies

10.1016/j.bioadv.2023.213476 · ExternalCitation · doi-reference

Mirtrons: microRNA biogenesis via splicing

10.1016/j.biochi.2011.06.017 · ExternalCitation · doi-reference

Adipocyte-derived extracellular vesicles promote breast cancer cell malignancy through HIF-1α activity

10.1016/j.canlet.2021.08.021 · ExternalCitation · doi-reference

Reducing breast cancer recurrence with weight loss, a vanguard trial: The Exercise and Nutrition to Enhance Recovery and Good Health for You (ENERGY) Trial

10.1016/j.cct.2012.12.003 · ExternalCitation · doi-reference

Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity

10.1016/j.cell.2017.08.035 · ExternalCitation · doi-reference

Metazoan MicroRNAs

10.1016/j.cell.2018.03.006 · ExternalCitation · doi-reference

Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

10.1016/j.cell.2020.07.009 · ExternalCitation · doi-reference

Body adipose tissue depots and treatment outcomes for women with breast cancer: A systematic review

10.1016/j.clnu.2024.03.010 · ExternalCitation · doi-reference

Molecular mechanisms of leptin and adiponectin in breast cancer

10.1016/j.ejca.2010.09.005 · ExternalCitation · doi-reference

Mechanisms of microRNA export in mammalian cells: From random release to selective secretion

10.1016/j.jbc.2026.113299 · ExternalCitation · doi-reference

Obesity and breast cancer—Role of estrogens and the molecular underpinnings of aromatase regulation in breast adipose tissue

10.1016/j.mce.2017.09.014 · ExternalCitation · doi-reference

The role of complement factor C3 in lipid metabolism

10.1016/j.molimm.2015.02.027 · ExternalCitation · doi-reference

Review of microRNA detection workflows from liquid biopsy for disease diagnostics

10.1017/erm.2025.2 · ExternalCitation · doi-reference

Adipose-derived circulating miRNAs regulate gene expression in other tissues

10.1038/nature21365 · ExternalCitation · doi-reference

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

10.1038/nature22341 · ExternalCitation · doi-reference

Rab27a and Rab27b control different steps of the exosome secretion pathway

10.1038/ncb2000 · ExternalCitation · doi-reference

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

10.1038/ncb2210 · ExternalCitation · doi-reference

Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis

10.1038/ncb3094 · ExternalCitation · doi-reference

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

10.1038/ncomms3980 · ExternalCitation · doi-reference

10.1038/nmeth.4185

10.1038/nmeth.4185 · ExternalCitation · doi-reference

MicroRNA biogenesis: Coordinated cropping and dicing

10.1038/nrm1644 · ExternalCitation · doi-reference

Regulation of microRNA biogenesis

10.1038/nrm3838 · ExternalCitation · doi-reference

Adipocyte-derived exosomal miRNAs: A novel mechanism for obesity-related disease

10.1038/pr.2014.202 · ExternalCitation · doi-reference

Targeting non-coding RNAs to overcome cancer therapy resistance

10.1038/s41392-022-00975-3 · ExternalCitation · doi-reference

Quantitative characterization of extracellular vesicle uptake and content delivery within mammalian cells

10.1038/s41467-021-22126-y · ExternalCitation · doi-reference

Elevated extracellular matrix protein 1 in circulating extracellular vesicles supports breast cancer progression under obesity conditions

10.1038/s41467-024-45995-5 · ExternalCitation · doi-reference

Crown-like structures in breast adipose tissue of breast cancer patients: Associations with CD68 expression, obesity, metabolic factors and prognosis

10.1038/s41523-021-00304-x · ExternalCitation · doi-reference

Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication

10.1038/s41556-018-0250-9 · ExternalCitation · doi-reference

Extracellular vesicles as a next-generation drug delivery platform

10.1038/s41565-021-00931-2 · ExternalCitation · doi-reference

Regulation of microRNA biogenesis and its crosstalk with other cellular pathways

10.1038/s41580-018-0059-1 · ExternalCitation · doi-reference

Two-tailed RT-qPCR panel for quality control of circulating microRNA studies

10.1038/s41598-019-40513-w · ExternalCitation · doi-reference

Differences in plasma microRNA content impair microRNA-based signature for breast cancer diagnosis in cohorts recruited from heterogeneous environmental sites

10.1038/s41598-021-91278-0 · ExternalCitation · doi-reference

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

10.1073/pnas.1019055108 · ExternalCitation · doi-reference

Secretory mechanisms and intercellular transfer of microRNAs in living cells

10.1074/jbc.m110.107821 · ExternalCitation · doi-reference

Effects of high fat diet-induced obesity on mammary tumorigenesis in the PyMT/MMTV murine model

10.1080/15384047.2018.1537574 · ExternalCitation · doi-reference

Weight loss reduces circulating micro-RNA related to obesity and breast cancer in postmenopausal women

10.1080/15592294.2022.2107841 · ExternalCitation · doi-reference

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): A position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

10.1080/20013078.2018.1535750 · ExternalCitation · doi-reference

Body mass index and survival in women with breast cancer-systematic literature review and meta-analysis of 82 follow-up studies

10.1093/annonc/mdu042 · ExternalCitation · doi-reference

Normalization of circulating microRNA expression data obtained by quantitative real-time RT-PCR

10.1093/bib/bbv056 · ExternalCitation · doi-reference

MicroRNA maturation: Stepwise processing and subcellular localization

10.1093/emboj/cdf476 · ExternalCitation · doi-reference

Reassessing the causal role of obesity in breast cancer susceptibility: A comprehensive multivariable Mendelian randomization investigating the distribution and timing of exposure

10.1093/ije/dyac143 · ExternalCitation · doi-reference

Reassessing the causal role of early-life adiposity in breast cancer: Could the apparent inverse associations be a manifestation of survival bias?

10.1093/ije/dyad027 · ExternalCitation · doi-reference

Secretory, endocrine and autocrine/paracrine function of the adipocyte

10.1093/jn/130.12.3110s · ExternalCitation · doi-reference

Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): An Abridged Explanation and Elaboration

10.1093/jnci/djy088 · ExternalCitation · doi-reference

Characterization of extracellular circulating microRNA

10.1093/nar/gkr254 · ExternalCitation · doi-reference

Circulating miR-221/222 expression as microRNA biomarker predicting tamoxifen treatment outcome: A case-control study

10.1097/ms9.0000000000001061 · ExternalCitation · doi-reference

Novel combination of serum microRNA for detecting breast cancer in the early stage

10.1111/cas.12880 · ExternalCitation · doi-reference

STARD 2015: An updated list of essential items for reporting diagnostic accuracy studies

10.1136/bmj.h5527 · ExternalCitation · doi-reference

Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles

10.1146/annurev-cellbio-101512-122326 · ExternalCitation · doi-reference

Obesity and cancer: Local and systemic mechanisms

10.1146/annurev-med-050913-022228 · ExternalCitation · doi-reference

Inflammation and increased aromatase expression occur in the breast tissue of obese women with breast cancer

10.1158/1940-6207.capr-11-0110 · ExternalCitation · doi-reference

Menopause is a determinant of breast adipose inflammation

10.1158/1940-6207.capr-14-0243 · ExternalCitation · doi-reference

Study of the preanalytical variables affecting the measurement of clinically relevant free-circulating microRNAs: Focus on sample matrix, platelet depletion, and storage conditions

10.11613/bm.2020.010703 · ExternalCitation · doi-reference

Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation

10.1172/jci123069 · ExternalCitation · doi-reference

10.1186/1472-6890-14-27

10.1186/1472-6890-14-27 · ExternalCitation · doi-reference

Obesity enhances nongenomic estrogen receptor crosstalk with the PI3K/Akt and MAPK pathways to promote in vitro measures of breast cancer progression

10.1186/bcr3453 · ExternalCitation · doi-reference

10.1186/s12864-018-4473-8

10.1186/s12864-018-4473-8 · ExternalCitation · doi-reference

10.1186/s12885-025-14447-8

10.1186/s12885-025-14447-8 · ExternalCitation · doi-reference

Regulation of autophagy by microRNAs in human breast cancer

10.1186/s12929-021-00715-9 · ExternalCitation · doi-reference

Extracellular vesicles-mediated intercellular communication: Roles in the tumor microenvironment and anti-cancer drug resistance

10.1186/s12943-019-0965-7 · ExternalCitation · doi-reference

miR-23b-3p, miR-126-3p and GAS5 delivered by extracellular vesicles inhibit breast cancer xenografts in zebrafish

10.1186/s12964-024-01936-9 · ExternalCitation · doi-reference

Exosomes as bio-inspired nanocarriers for RNA delivery: Preparation and applications

10.1186/s12967-022-03325-7 · ExternalCitation · doi-reference

Analysis of circulating extracellular vesicle derived microRNAs in breast cancer patients with obesity: A potential role for Let-7a

10.1186/s12967-023-04075-w · ExternalCitation · doi-reference

Plasma exosome microRNAs are indicative of breast cancer

10.1186/s13058-016-0753-x · ExternalCitation · doi-reference

Impact of obesity on breast cancer recurrence and minimal residual disease

10.1186/s13058-018-1087-7 · ExternalCitation · doi-reference

Obesity increases DNA damage in the breast epithelium

10.1186/s13058-025-01961-7 · ExternalCitation · doi-reference

Extracellular vesicles-derived miR-21 as a biomarker for early diagnosis and tumor activity in breast cancer subtypes

10.1186/s40364-025-00724-y · ExternalCitation · doi-reference

Obesity and Cancer Mechanisms: Tumor Microenvironment and Inflammation

10.1200/jco.2016.67.4283 · ExternalCitation · doi-reference

Obesity and Breast Cancer Prognosis: Evidence, Challenges, and Opportunities

10.1200/jco.2016.68.4480 · ExternalCitation · doi-reference

Paracrine and endocrine effects of adipose tissue on cancer development and progression

10.1210/er.2010-0030 · ExternalCitation · doi-reference

10.1371/journal.pone.0064795

10.1371/journal.pone.0064795 · ExternalCitation · doi-reference

10.1371/journal.pone.0112481

10.1371/journal.pone.0112481 · ExternalCitation · doi-reference

10.1371/journal.pone.0188980

10.1371/journal.pone.0188980 · ExternalCitation · doi-reference

10.1371/journal.pone.0222024

10.1371/journal.pone.0222024 · ExternalCitation · doi-reference

10.1371/journal.pone.0292678

10.1371/journal.pone.0292678 · ExternalCitation · doi-reference

Obesity and inflammation: New insights into breast cancer development and progression

10.14694/edbook_am.2013.33.46 · ExternalCitation · doi-reference

Breast adipose tissue-derived extracellular vesicles from obese women alter tumor cell metabolism

10.15252/embr.202357339 · ExternalCitation · doi-reference

Breast cancer metastasis in obesity: Extracellular vesicles as drivers

10.1530/erc-25-0312 · ExternalCitation · doi-reference

Obesity and Breast Cancer: Molecular Interconnections and Potential Clinical Applications

10.1634/theoncologist.2015-0351 · ExternalCitation · doi-reference

Breaking free: Endocytosis and endosomal escape of extracellular vesicles

10.20517/evcna.2023.26 · ExternalCitation · doi-reference

Extracellular vesicle-mediated chemoresistance in breast cancer: Focus on miRNA cargo

10.20517/evcna.2024.90 · ExternalCitation · doi-reference

qPCR-based methods for expression analysis of miRNAs

10.2144/btn-2019-0065 · ExternalCitation · doi-reference

Bubble Ticket Trip: Exploring the Mechanism of miRNA Sorting into Exosomes and Maintaining the Stability of Tumor Microenvironment

10.2147/ijn.s498599 · ExternalCitation · doi-reference

An Update of Extracellular Vesicle Involvement in Different Steps of Cancer Metastasis and Targeting Strategies

10.2174/0109298673273299231121044055 · ExternalCitation · doi-reference

Extracellular RNAs Are Associated with Insulin Resistance and Metabolic Phenotypes

10.2337/dc16-1354 · ExternalCitation · doi-reference

10.3389/fcell.2021.731062

10.3389/fcell.2021.731062 · ExternalCitation · doi-reference

10.3389/fendo.2018.00402

10.3389/fendo.2018.00402 · ExternalCitation · doi-reference

10.3389/fendo.2023.1202493

10.3389/fendo.2023.1202493 · ExternalCitation · doi-reference

10.3389/fendo.2024.1409000

10.3389/fendo.2024.1409000 · ExternalCitation · doi-reference

10.3389/fgene.2019.00478

10.3389/fgene.2019.00478 · ExternalCitation · doi-reference

10.3389/fimmu.2021.608680

10.3389/fimmu.2021.608680 · ExternalCitation · doi-reference

10.3389/fonc.2019.00596

10.3389/fonc.2019.00596 · ExternalCitation · doi-reference

10.3389/fonc.2020.581007

10.3389/fonc.2020.581007 · ExternalCitation · doi-reference

10.3389/fonc.2021.668464

10.3389/fonc.2021.668464 · ExternalCitation · doi-reference

10.3389/fonc.2021.704893

10.3389/fonc.2021.704893 · ExternalCitation · doi-reference

10.3389/fonc.2022.897205

10.3389/fonc.2022.897205 · ExternalCitation · doi-reference

10.3389/fonc.2024.1374674

10.3389/fonc.2024.1374674 · ExternalCitation · doi-reference

10.3390/bioengineering9110675

10.3390/bioengineering9110675 · ExternalCitation · doi-reference

10.3390/biom12010132

10.3390/biom12010132 · ExternalCitation · doi-reference

10.3390/cancers11010062

10.3390/cancers11010062 · ExternalCitation · doi-reference

10.3390/cancers13092222

10.3390/cancers13092222 · ExternalCitation · doi-reference

10.3390/cancers13112680

10.3390/cancers13112680 · ExternalCitation · doi-reference

10.3390/cancers13133328

10.3390/cancers13133328 · ExternalCitation · doi-reference

10.3390/cancers14092317

10.3390/cancers14092317 · ExternalCitation · doi-reference

10.3390/cancers14153818

10.3390/cancers14153818 · ExternalCitation · doi-reference

10.3390/cancers14163908

10.3390/cancers14163908 · ExternalCitation · doi-reference

10.3390/cells11091375

10.3390/cells11091375 · ExternalCitation · doi-reference

10.3390/cells8111465

10.3390/cells8111465 · ExternalCitation · doi-reference

10.3390/genes13020328

10.3390/genes13020328 · ExternalCitation · doi-reference

10.3390/ijms20215364

10.3390/ijms20215364 · ExternalCitation · doi-reference

10.3390/ijms22073362

10.3390/ijms22073362 · ExternalCitation · doi-reference

10.3390/ijms241713085

10.3390/ijms241713085 · ExternalCitation · doi-reference

10.3390/ijms25031469

10.3390/ijms25031469 · ExternalCitation · doi-reference

10.3390/ijms26189101

10.3390/ijms26189101 · ExternalCitation · doi-reference

10.3390/ijms26199666

10.3390/ijms26199666 · ExternalCitation · doi-reference

10.3390/metabo13050675

10.3390/metabo13050675 · ExternalCitation · doi-reference

10.3390/pharmaceutics15020598

10.3390/pharmaceutics15020598 · ExternalCitation · doi-reference

Routes and mechanisms of extracellular vesicle uptake

10.3402/jev.v3.24641 · ExternalCitation · doi-reference

Adipocyte-derived extracellular vesicles sustain mitochondrial metabolism in breast cancer cells: New insights into the cross-talk between cancer cells and the tumor microenvironment

10.3892/ijo.2025.5806 · ExternalCitation · doi-reference

Obesity and Breast Cancer: The Role of Crown-Like Structures in Breast Adipose Tissue in Tumor Progression, Prognosis, and Therapy

10.4048/jbc.2020.23.e35 · ExternalCitation · doi-reference

MicroRNAs: New Biomarkers for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Breast Cancer

10.7150/thno.11543 · ExternalCitation · doi-reference

Adipocyte-Derived Exosomal MiR-27a Induces Insulin Resistance in Skeletal Muscle Through Repression of PPARγ

10.7150/thno.22565 · ExternalCitation · doi-reference

Tumor-derived EV miRNA signatures surpass total EV miRNA in supplementing mammography for precision breast cancer diagnosis

10.7150/thno.99245 · ExternalCitation · doi-reference

Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates

10.7554/elife.71982 · ExternalCitation · doi-reference