Research graph
References from NT-3-Expressing Olfactory Ensheathing Cells Reduce Brain Aβ1–42 Accumulation and Improve Cognitive Performance in a Rat Model of Alzheimer’s Disease. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1002/alz.13809
10.1002/alz.13809 · External reference
The diagnosis of young-onset dementia
10.1016/s1474-4422(10)70159-9 · 2010 · External reference
Recent advances in stem cell therapy for neurodegenerative disease: Three dimensional tracing and its emerging use
10.4252/wjsc.v13.i9.1215 · 2021 · External reference
Cerebellum in neurodegenerative diseases: Advances, challenges, and prospects
10.1016/j.isci.2024.111194 · 2024 · External reference
10.3390/ijms241411757
10.3390/ijms241411757 · External reference
Neuroinflammation in Alzheimer’s disease: Microglial signature and their relevance to disease
10.1186/s41232-023-00277-3 · 2023 · External reference
10.3389/fmed.2024.1474043
10.3389/fmed.2024.1474043 · External reference
Lecanemab in Early Alzheimer’s Disease
10.1056/nejmoa2212948 · 2023 · External reference
Brain-derived neurotrophic factor modified human umbilical cord mesenchymal stem cells-derived cholinergic-like neurons improve spatial learning and memory ability in Alzheimer’s disease rats
10.1016/j.brainres.2018.12.034 · 2019 · External reference
BDNF-overexpressing human mesenchymal stem cells mediate increased neuronal protection in vitro
10.1002/jnr.24488 · 2019 · External reference
10.3389/fncel.2021.629356
10.3389/fncel.2021.629356 · External reference
Application of neurotrophic factors as a therapeutic approach for neurodegenerative diseases
10.5607/en25023 · 2025 · External reference
Cell therapy for central nervous system disorders: Current obstacles to progress
10.1111/cns.13247 · 2020 · External reference
Stem cells in central nervous system diseases: Promising therapeutic strategies
10.1016/j.expneurol.2023.114543 · 2023 · External reference
10.3390/ijms252212378
10.3390/ijms252212378 · External reference
A pilot study of clinical cell therapies in Alzheimer’s disease
10.26599/jnr.2021.9040023 · 2021 · External reference
Transplantation of autologous olfactory ensheathing cells in complete human spinal cord injury
10.3727/096368912x663532 · 2013 · External reference
Designing olfactory ensheathing cell transplantation therapies: Influence of cell microenvironment
10.1177/09636897221125685 · 2022 · External reference
10.3389/fimmu.2023.1280186
10.3389/fimmu.2023.1280186 · External reference
The effect of transplantation of ensheathing cells of the olfactory mucosa into the hippocampal area on the restoration of cognitive abilities in rats with experimental Alzheimer’s disease
10.1007/s10517-024-06293-8 · 2024 · External reference
The study of cognitive functions of rats with experimental Alzheimer’s disease after transplantation of transduced olfactory ensheathing cells expressing nerve growth factor
10.1007/s10517-025-06446-3 · 2025 · External reference
Isolation of rat olfactory ensheathing cells and their use in the therapy of posttraumatic cysts of the spinal cord
10.1007/s10517-018-4114-x · 2018 · External reference
A new insight into aggregation of oncolytic adenovirus Ad5-delta-24-RGD during CsCl gradient ultracentrifugation
10.1038/s41598-021-94573-y · 2021 · External reference
Efficient gene transduction of dispersed islet cells in culture using fiber-modified adenoviral vectors
10.3727/215517915x689083 · 2015 · External reference
HaCaT keratinocytes response on antimicrobial atelocollagen substrates: Extent of cytotoxicity, cell viability and proliferation
10.3390/jfb5020043 · 2014 · External reference
An animal model of Alzheimer disease based on the intrahippocampal injection of amyloid β-peptide (1-42)
10.1007/978-1-4939-7571-6_25 · 2018 · External reference
Unresolved reference
External reference
Application of behavioral tests for evaluation of an experimental model of Alzheimer’s disease in female rats
10.1007/s10517-023-05823-0 · 2023 · External reference
Morris water maze test for learning and memory deficits in Alzheimer’s disease model mice
2011 · External reference
Palmitoylethanolamide controls reactive gliosis and exerts neuroprotective functions in a rat model of Alzheimer’s disease
10.1038/cddis.2014.376 · 2014 · External reference
Which memory task for my mouse? A systematic review of spatial memory performance in the Tg2576 Alzheimer’s mouse model
10.3233/jad-2011-101827 · 2011 · External reference
Virotherapy as gene deliver for anti-cancer therapy: A review article
10.31557/apjcp.2025.26.11.3895 · 2025 · External reference
10.3390/v16071094
10.3390/v16071094 · External reference
Effect of adenovirus serotype 5 fiber and penton modifications on in vivo tropism in rats
10.1016/j.ymthe.2004.05.020 · 2004 · External reference
Neurotrophic and migratory properties of an olfactory ensheathing cell line
10.1002/1098-1136(200103)33:3<225::aid-glia1021>3.0.co;2-y · 2001 · External reference
Effect of neurotrophin-3 genetically modified olfactory ensheathing cells transplantation on spinal cord injury
10.3727/096368910x492634 · 2010 · External reference
The role of the dentate gyrus in mediating hippocampal functions: The healthy brain
2022 · External reference
Spontaneous and induced nontransgenic animal models of AD: Modeling AD using combinatorial approach
10.1177/1533317513488914 · 2013 · External reference
Animal models of Alzheimer disease
10.1101/cshperspect.a006320 · 2012 · External reference
Comparative study of injected Alzheimer’s disease models in rats: Insights from experimental research
10.3390/pathophysiology31040047 · 2024 · External reference
Recombinant neurotrophin-3 with the ability to penetrate the blood-brain barrier: A new strategy against Alzheimer’s disease
10.1016/j.ijbiomac.2024.139359 · 2025 · External reference
10.3389/fnagi.2025.1569181
10.3389/fnagi.2025.1569181 · External reference
10.3390/jdad2030025
10.3390/jdad2030025 · External reference
Distinct effects of the hippocampal transplantation of neural and mesenchymal stem cells in a transgenic model of Alzheimer’s disease
10.1007/s12015-021-10321-9 · 2022 · External reference
10.3389/fnagi.2018.00250
10.3389/fnagi.2018.00250 · External reference
Brain-derived neurotrophic factor and neurotrophin-3 levels in Alzheimer’s disease brains
10.1016/s0736-5748(00)00046-0 · 2000 · External reference
Regional specificity of alterations in NGF, BDNF and NT-3 levels in Alzheimer’s disease
10.1097/00001756-199611250-00024 · 1996 · External reference
Vitamin D3 and cognitive deficit in diabetic rats through regulating neurotrophins and enhancing cholinergic transmission pathway
2021 · External reference
Transplantation of olfactory ensheathing cells on functional recovery and neuropathic pain after spinal cord injury; systematic review and meta-analysis
2018 · External reference
Translational potential of olfactory mucosa for the study of neuropsychiatric illness
10.1038/tp.2014.141 · 2015 · External reference
Effects of neural stem cell transplantation in Alzheimer’s disease models
10.1186/s12929-020-0622-x · 2020 · External reference
Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer’s disease
10.1038/nm.1912 · 2009 · External reference
Brain-derived neurotrophic factor in Alzheimer’s disease and its pharmaceutical potential
10.1186/s40035-022-00279-0 · 2022 · External reference
BDNF Protects Against Neuronal Damage Induced by TNF and β-Amyloid Peptides by Targeting JNK Activation
10.1007/s11064-026-04740-8 · 2026 · External reference
10.3389/fimmu.2022.1098212
10.3389/fimmu.2022.1098212 · External reference
Enhancing the Therapeutic Potential of Olfactory Ensheathing Cells in Spinal Cord Repair Using Neurotrophins
10.1177/0963689718759472 · 2018 · External reference
Therapeutic Potential of Astrocyte Transplantation
10.1177/09636897221105499 · 2022 · External reference
Promoting Alzheimer’s disease research and therapy with stem cell technology
10.1186/s13287-024-03737-w · 2024 · External reference
Neural stem cells improve learning and memory in rats with Alzheimer’s disease
10.1159/000124979 · 2008 · External reference
Effects of lateral ventricular transplantation of bone marrow-derived mesenchymal stem cells modified with brain-derived neurotrophic factor gene on cognition in a rat model of Alzheimer’s disease
2012 · External reference
Amyloid-β and Tau in Alzheimer’s disease: Pathogenesis, mechanisms, and interplay
10.1038/s41419-025-08186-8 · 2026 · External reference
Brain-Derived Neurotrophic Factor Protects Against Tau-Related Neurodegeneration of Alzheimer’s Disease
10.1038/tp.2016.186 · 2016 · External reference
Immunological instability of persistent adenovirus vectors in the brain: Peripheral exposure to vector leads to renewed inflammation, reduced gene expression, and demyelination
10.1523/jneurosci.16-09-03045.1996 · 1996 · External reference
One-year expression from high-capacity adenoviral vectors in the brains of animals with pre-existing anti-adenoviral immunity: Clinical implications
10.1038/sj.mt.6300305 · 2007 · External reference
AAV-based in vivo gene therapy for neurological disorders
10.1038/s41573-023-00766-7 · 2023 · External reference
Viral vectors for gene delivery to the central nervous system
10.1016/b978-0-323-90120-8.00001-0 · 2024 · External reference
Olfactory cleft biopsy analysis of Alzheimer’s disease pathobiology across disease stages
10.1038/s41467-026-70099-7 · 2026 · External reference
10.3390/cells11040676
10.3390/cells11040676 · External reference
Neurotrophic and migratory properties of an olfactory ensheathing cell line
10.1002/1098-1136(200103)33:3<225::aid-glia1021>3.0.co;2-y · ExternalCitation · doi-reference
10.1002/alz.13809
10.1002/alz.13809 · ExternalCitation · doi-reference
BDNF-overexpressing human mesenchymal stem cells mediate increased neuronal protection in vitro
10.1002/jnr.24488 · ExternalCitation · doi-reference
An animal model of Alzheimer disease based on the intrahippocampal injection of amyloid β-peptide (1-42)
10.1007/978-1-4939-7571-6_25 · ExternalCitation · doi-reference
Isolation of rat olfactory ensheathing cells and their use in the therapy of posttraumatic cysts of the spinal cord
10.1007/s10517-018-4114-x · ExternalCitation · doi-reference
Application of behavioral tests for evaluation of an experimental model of Alzheimer’s disease in female rats
10.1007/s10517-023-05823-0 · ExternalCitation · doi-reference
The effect of transplantation of ensheathing cells of the olfactory mucosa into the hippocampal area on the restoration of cognitive abilities in rats with experimental Alzheimer’s disease
10.1007/s10517-024-06293-8 · ExternalCitation · doi-reference
The study of cognitive functions of rats with experimental Alzheimer’s disease after transplantation of transduced olfactory ensheathing cells expressing nerve growth factor
10.1007/s10517-025-06446-3 · ExternalCitation · doi-reference
BDNF Protects Against Neuronal Damage Induced by TNF and β-Amyloid Peptides by Targeting JNK Activation
10.1007/s11064-026-04740-8 · ExternalCitation · doi-reference
Distinct effects of the hippocampal transplantation of neural and mesenchymal stem cells in a transgenic model of Alzheimer’s disease
10.1007/s12015-021-10321-9 · ExternalCitation · doi-reference
Viral vectors for gene delivery to the central nervous system
10.1016/b978-0-323-90120-8.00001-0 · ExternalCitation · doi-reference
Brain-derived neurotrophic factor modified human umbilical cord mesenchymal stem cells-derived cholinergic-like neurons improve spatial learning and memory ability in Alzheimer’s disease rats
10.1016/j.brainres.2018.12.034 · ExternalCitation · doi-reference
Stem cells in central nervous system diseases: Promising therapeutic strategies
10.1016/j.expneurol.2023.114543 · ExternalCitation · doi-reference
Recombinant neurotrophin-3 with the ability to penetrate the blood-brain barrier: A new strategy against Alzheimer’s disease
10.1016/j.ijbiomac.2024.139359 · ExternalCitation · doi-reference
Cerebellum in neurodegenerative diseases: Advances, challenges, and prospects
10.1016/j.isci.2024.111194 · ExternalCitation · doi-reference
Effect of adenovirus serotype 5 fiber and penton modifications on in vivo tropism in rats
10.1016/j.ymthe.2004.05.020 · ExternalCitation · doi-reference
Brain-derived neurotrophic factor and neurotrophin-3 levels in Alzheimer’s disease brains
10.1016/s0736-5748(00)00046-0 · ExternalCitation · doi-reference
The diagnosis of young-onset dementia
10.1016/s1474-4422(10)70159-9 · ExternalCitation · doi-reference
Palmitoylethanolamide controls reactive gliosis and exerts neuroprotective functions in a rat model of Alzheimer’s disease
10.1038/cddis.2014.376 · ExternalCitation · doi-reference
Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer’s disease
10.1038/nm.1912 · ExternalCitation · doi-reference
Amyloid-β and Tau in Alzheimer’s disease: Pathogenesis, mechanisms, and interplay
10.1038/s41419-025-08186-8 · ExternalCitation · doi-reference
Olfactory cleft biopsy analysis of Alzheimer’s disease pathobiology across disease stages
10.1038/s41467-026-70099-7 · ExternalCitation · doi-reference
AAV-based in vivo gene therapy for neurological disorders
10.1038/s41573-023-00766-7 · ExternalCitation · doi-reference
A new insight into aggregation of oncolytic adenovirus Ad5-delta-24-RGD during CsCl gradient ultracentrifugation
10.1038/s41598-021-94573-y · ExternalCitation · doi-reference
One-year expression from high-capacity adenoviral vectors in the brains of animals with pre-existing anti-adenoviral immunity: Clinical implications
10.1038/sj.mt.6300305 · ExternalCitation · doi-reference
Translational potential of olfactory mucosa for the study of neuropsychiatric illness
10.1038/tp.2014.141 · ExternalCitation · doi-reference
Brain-Derived Neurotrophic Factor Protects Against Tau-Related Neurodegeneration of Alzheimer’s Disease
10.1038/tp.2016.186 · ExternalCitation · doi-reference
Lecanemab in Early Alzheimer’s Disease
10.1056/nejmoa2212948 · ExternalCitation · doi-reference
Regional specificity of alterations in NGF, BDNF and NT-3 levels in Alzheimer’s disease
10.1097/00001756-199611250-00024 · ExternalCitation · doi-reference
Animal models of Alzheimer disease
10.1101/cshperspect.a006320 · ExternalCitation · doi-reference
Cell therapy for central nervous system disorders: Current obstacles to progress
10.1111/cns.13247 · ExternalCitation · doi-reference
Neural stem cells improve learning and memory in rats with Alzheimer’s disease
10.1159/000124979 · ExternalCitation · doi-reference
Enhancing the Therapeutic Potential of Olfactory Ensheathing Cells in Spinal Cord Repair Using Neurotrophins
10.1177/0963689718759472 · ExternalCitation · doi-reference
Therapeutic Potential of Astrocyte Transplantation
10.1177/09636897221105499 · ExternalCitation · doi-reference
Designing olfactory ensheathing cell transplantation therapies: Influence of cell microenvironment
10.1177/09636897221125685 · ExternalCitation · doi-reference
Spontaneous and induced nontransgenic animal models of AD: Modeling AD using combinatorial approach
10.1177/1533317513488914 · ExternalCitation · doi-reference
Effects of neural stem cell transplantation in Alzheimer’s disease models
10.1186/s12929-020-0622-x · ExternalCitation · doi-reference
Promoting Alzheimer’s disease research and therapy with stem cell technology
10.1186/s13287-024-03737-w · ExternalCitation · doi-reference
Brain-derived neurotrophic factor in Alzheimer’s disease and its pharmaceutical potential
10.1186/s40035-022-00279-0 · ExternalCitation · doi-reference
Neuroinflammation in Alzheimer’s disease: Microglial signature and their relevance to disease
10.1186/s41232-023-00277-3 · ExternalCitation · doi-reference
Immunological instability of persistent adenovirus vectors in the brain: Peripheral exposure to vector leads to renewed inflammation, reduced gene expression, and demyelination
10.1523/jneurosci.16-09-03045.1996 · ExternalCitation · doi-reference
A pilot study of clinical cell therapies in Alzheimer’s disease
10.26599/jnr.2021.9040023 · ExternalCitation · doi-reference
Virotherapy as gene deliver for anti-cancer therapy: A review article
10.31557/apjcp.2025.26.11.3895 · ExternalCitation · doi-reference
Which memory task for my mouse? A systematic review of spatial memory performance in the Tg2576 Alzheimer’s mouse model
10.3233/jad-2011-101827 · ExternalCitation · doi-reference
10.3389/fimmu.2022.1098212
10.3389/fimmu.2022.1098212 · ExternalCitation · doi-reference
10.3389/fimmu.2023.1280186
10.3389/fimmu.2023.1280186 · ExternalCitation · doi-reference
10.3389/fmed.2024.1474043
10.3389/fmed.2024.1474043 · ExternalCitation · doi-reference
10.3389/fnagi.2018.00250
10.3389/fnagi.2018.00250 · ExternalCitation · doi-reference
10.3389/fnagi.2025.1569181
10.3389/fnagi.2025.1569181 · ExternalCitation · doi-reference
10.3389/fncel.2021.629356
10.3389/fncel.2021.629356 · ExternalCitation · doi-reference
10.3390/cells11040676
10.3390/cells11040676 · ExternalCitation · doi-reference
10.3390/ijms241411757
10.3390/ijms241411757 · ExternalCitation · doi-reference
10.3390/ijms252212378
10.3390/ijms252212378 · ExternalCitation · doi-reference
10.3390/jdad2030025
10.3390/jdad2030025 · ExternalCitation · doi-reference
HaCaT keratinocytes response on antimicrobial atelocollagen substrates: Extent of cytotoxicity, cell viability and proliferation
10.3390/jfb5020043 · ExternalCitation · doi-reference
Comparative study of injected Alzheimer’s disease models in rats: Insights from experimental research
10.3390/pathophysiology31040047 · ExternalCitation · doi-reference
10.3390/v16071094
10.3390/v16071094 · ExternalCitation · doi-reference
Effect of neurotrophin-3 genetically modified olfactory ensheathing cells transplantation on spinal cord injury
10.3727/096368910x492634 · ExternalCitation · doi-reference
Transplantation of autologous olfactory ensheathing cells in complete human spinal cord injury
10.3727/096368912x663532 · ExternalCitation · doi-reference
Efficient gene transduction of dispersed islet cells in culture using fiber-modified adenoviral vectors
10.3727/215517915x689083 · ExternalCitation · doi-reference
Recent advances in stem cell therapy for neurodegenerative disease: Three dimensional tracing and its emerging use
10.4252/wjsc.v13.i9.1215 · ExternalCitation · doi-reference
Application of neurotrophic factors as a therapeutic approach for neurodegenerative diseases
10.5607/en25023 · ExternalCitation · doi-reference
