References

Rapid healing of venous ulcers and lack of clinical rejection with an allogeneic cultured human skin equivalent. Human Skin Equivalent Investigators Group

10.1001/archderm.134.3.293 · ExternalCitation · doi-reference

10.1002/14651858.cd005486.pub2

10.1002/14651858.cd005486.pub2 · ExternalCitation · doi-reference

Upregulating Hif-1α by Hydrogel Nanofibrous Scaffolds for Rapidly Recruiting Angiogenesis Relative Cells in Diabetic Wound

10.1002/adhm.201501018 · ExternalCitation · doi-reference

Chitosan-Based Hydrogels as Antibacterial/Antioxidant/Anti-Inflammation Multifunctional Dressings for Chronic Wound Healing

10.1002/adhm.202401490 · ExternalCitation · doi-reference

Thrombin-Responsive Transcutaneous Patch for Auto-Anticoagulant Regulation

10.1002/adma.201604043 · ExternalCitation · doi-reference

Randomized controlled trial and cost-effectiveness analysis of silver-donating antimicrobial dressings for venous leg ulcers (VULCAN trial)

10.1002/bjs.6786 · ExternalCitation · doi-reference

Interactions of heparin with human skin cells: Binding, location, and transdermal penetration

10.1002/jbm.a.10085 · ExternalCitation · doi-reference

Effect of the sterilization method on the performance of collagen type I on chronic wound parameters in vitro

10.1002/jbm.b.31338 · ExternalCitation · doi-reference

Fluorescence analysis of the labile iron pool of mammalian cells

10.1006/abio.1997.2126 · ExternalCitation · doi-reference

Agranulocytosis associated with calcium dobesilate clinical course and risk estimation with the case-control and the case-population approaches

10.1007/s002280000190 · ExternalCitation · doi-reference

Multi-crosslinked hydrogels with strong wet adhesion, self-healing, antibacterial property, reactive oxygen species scavenging activity, and on-demand removability for seawater-immersed wound healing

10.1016/j.actbio.2023.01.045 · ExternalCitation · doi-reference

Recent advances in tannic acid-based gels: Design, properties, and applications

10.1016/j.cis.2025.103425 · ExternalCitation · doi-reference

Skin iron deposition characterises lipodermatosclerosis and leg ulcer

10.1016/j.ejvs.2010.08.015 · ExternalCitation · doi-reference

Editor’s Choice—European Society for Vascular Surgery (ESVS) 2022 Clinical Practice Guidelines on the Management of Chronic Venous Disease of the Lower Limbs

10.1016/j.ejvs.2021.12.024 · ExternalCitation · doi-reference

Polysaccharide- and protein-based hydrogel dressings that enhance wound healing: A review

10.1016/j.ijbiomac.2024.135482 · ExternalCitation · doi-reference

Hemostatic and antimicrobial properties of chitosan-based wound healing dressings: A review

10.1016/j.ijbiomac.2025.141570 · ExternalCitation · doi-reference

Hydrogel-based dressing for wound healing: A systematic review of clinical trials

10.1016/j.ijbiomac.2025.142322 · ExternalCitation · doi-reference

Preparation of double network hydrogel wound dressing based on starch/hyaluronic acid through host-guest interaction and Diels-Alder reaction

10.1016/j.jcis.2025.138809 · ExternalCitation · doi-reference

Pressure-induced cellular senescence: A mechanism linking venous hypertension to venous ulcers

10.1016/j.jss.2004.09.013 · ExternalCitation · doi-reference

Development of a core outcome set for use in research evaluations of interventions for venous leg ulceration: International eDelphi consensus

10.1016/j.jtv.2024.02.006 · ExternalCitation · doi-reference

Hemochromatosis C282Y gene mutation increases the risk of venous leg ulceration

10.1016/j.jvs.2005.04.003 · ExternalCitation · doi-reference

Pathophysiology of venous ulceration

10.1016/j.jvsv.2017.03.015 · ExternalCitation · doi-reference

Venous leg ulcers and prevalence of surgically correctable reflux disease in a national registry

10.1016/j.jvsv.2022.11.005 · ExternalCitation · doi-reference

Dysfunctional pericellular hyaluronan deposition contributes to attenuated CD44/EGFR co-localization and impaired myofibroblast differentiation in chronic wound fibroblasts

10.1016/j.yexcr.2025.114646 · ExternalCitation · doi-reference

Which venous leg ulcers will heal with limb compression bandages?

10.1016/s0002-9343(00)00379-x · ExternalCitation · doi-reference

Effect of topical and oral diclofenac on superficial thrombophlebitis caused by intravenous infusion

10.1016/s0025-7753(00)71300-5 · ExternalCitation · doi-reference

Altered proliferative responses of dermal fibroblasts to TGF-beta1 may contribute to chronic venous stasis ulcer

10.1016/s0741-5214(02)75295-6 · ExternalCitation · doi-reference

Mussel-Inspired Adhesive and Tough Hydrogel Based on Nanoclay Confined Dopamine Polymerization

10.1021/acsnano.6b05318 · ExternalCitation · doi-reference

Oops they did it again! Carbon nanotubes hoax scientists in viability assays

10.1021/nl060177c · ExternalCitation · doi-reference

Allergic contact dermatitis in venous leg ulcer patients

10.1034/j.1600-0536.2003.00111.x · ExternalCitation · doi-reference

Designing hydrogels for controlled drug delivery

10.1038/natrevmats.2016.71 · ExternalCitation · doi-reference

A method for growing a biofilm under low shear at the air-liquid interface using the drip flow biofilm reactor

10.1038/nprot.2009.59 · ExternalCitation · doi-reference

Extracellular matrix and cellular senescence in venous leg ulcers

10.1038/s41598-021-99643-9 · ExternalCitation · doi-reference

A MMP9-responsive nanozyme hydrogel to promote diabetic wound healing by reconstructing the balance of pro-inflammation and anti-inflammation

10.1039/d4tb02857k · ExternalCitation · doi-reference

Effects of irradiation sterilization on the physicochemical and functional properties of commercial biomedical hydrogels

10.1039/d5bm01305d · ExternalCitation · doi-reference

Progress in the application of conductive hydrogels in wound healing: A review

10.1039/d5na00650c · ExternalCitation · doi-reference

A multicentre study of percentage change in venous leg ulcer area as a prognostic index of healing at 24 weeks

10.1046/j.1365-2133.2000.03478.x · ExternalCitation · doi-reference

Analysis of the acute and chronic wound environments: The role of proteases and their inhibitors

10.1046/j.1524-475x.1999.00442.x · ExternalCitation · doi-reference

Defining the human and health care costs of chronic venous insufficiency

10.1053/j.semvascsurg.2021.02.007 · ExternalCitation · doi-reference

A Randomized Trial of Early Endovenous Ablation in Venous Ulceration

10.1056/nejmoa1801214 · ExternalCitation · doi-reference

Effect of sterilization treatment on mechanical properties, biodegradation, bioactivity and printability of GelMA hydrogels

10.1088/1748-605x/aba40c · ExternalCitation · doi-reference

Splinting Strategies to Overcome Confounding Wound Contraction in Experimental Animal Models

10.1089/wound.2012.0424 · ExternalCitation · doi-reference

Moist Wound Healing with Commonly Available Dressings

10.1089/wound.2020.1232 · ExternalCitation · doi-reference

Associations Among Wound-Related Factors Including Biofilm, Wound-Related Symptoms and Systemic Inflammation in Older Adults with Chronic Venous Leg Ulcers

10.1089/wound.2023.0028 · ExternalCitation · doi-reference

Commercial wound dressings for the treatment of exuding wounds: An in-depth physico-chemical comparative study

10.1093/burnst/tkac024 · ExternalCitation · doi-reference

The emerging role and therapeutical implications of ferroptosis in wound healing

10.1093/burnst/tkae082 · ExternalCitation · doi-reference

Innovations in hydrogel therapies for diabetic wound healing: Bridging the gap between pathophysiology and clinical application

10.1093/burnst/tkaf025 · ExternalCitation · doi-reference

The static stiffness index: A simple method to assess the elastic property of compression material in vivo

10.1097/00042728-200506000-00002 · ExternalCitation · doi-reference

Serum iron and matrix metalloproteinase-9 variations in limbs affected by chronic venous disease and venous leg ulcers

10.1097/00042728-200506000-00005 · ExternalCitation · doi-reference

Randomized Controlled Trial Comparing Collagen/Oxidized Regenerated Cellulose/Silver to Standard of Care in the Management of Venous Leg Ulcers

10.1097/01.asw.0000524452.80170.d8 · ExternalCitation · doi-reference

Contact Sensitization in Patients with Chronic Leg Ulcers: Results of a 5-Year Retrospective Analysis

10.1097/01.asw.0000582628.52901.43 · ExternalCitation · doi-reference

Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9

10.1111/1523-1747.ep12359590 · ExternalCitation · doi-reference

Health economic burden that different wound types impose on the UK’s National Health Service

10.1111/iwj.12603 · ExternalCitation · doi-reference

Cost of managing patients with venous leg ulcers

10.1111/iwj.13366 · ExternalCitation · doi-reference

Fluid handling by foam wound dressings: From engineering theory to advanced laboratory performance evaluations

10.1111/iwj.14674 · ExternalCitation · doi-reference

Efficacy and safety of platelet-rich plasma in the treatment of venous ulcers: A systematic review and meta-analysis of randomized controlled trials

10.1111/iwj.14736 · ExternalCitation · doi-reference

Protein Biomarkers in Venous Leg Ulcer Fluid: A Systematic Review

10.1111/iwj.70675 · ExternalCitation · doi-reference

Quantitative and reproducible murine model of excisional wound healing

10.1111/j.1067-1927.2004.12404.x · ExternalCitation · doi-reference

Pericapillary fibrin cuffs in venous disease. A reappraisal

10.1111/j.1524-4725.1997.tb00759.x · ExternalCitation · doi-reference

Effect of oxidised regenerated cellulose/collagen matrix on proteases in wound exudate of patients with chronic venous ulceration

10.1111/j.1742-481x.2007.00367.x · ExternalCitation · doi-reference

Randomized controlled trial on collagen/oxidized regenerated cellulose/silver treatment

10.1111/wrr.12020 · ExternalCitation · doi-reference

The murine excisional wound model: Contraction revisited

10.1111/wrr.12338 · ExternalCitation · doi-reference

Association of biofilm and microbial metrics with healing rate in older adults with chronic venous leg ulcers

10.1111/wrr.13230 · ExternalCitation · doi-reference

Long term results of compression therapy alone versus compression plus surgery in chronic venous ulceration (ESCHAR): Randomised controlled trial

10.1136/bmj.39216.542442.be · ExternalCitation · doi-reference

Observer bias in randomised clinical trials with binary outcomes: Systematic review of trials with both blinded and non-blinded outcome assessors

10.1136/bmj.e1119 · ExternalCitation · doi-reference

Cohort study evaluating the burden of wounds to the UK’s National Health Service in 2017/2018: Update from 2012/2013

10.1136/bmjopen-2020-045253 · ExternalCitation · doi-reference

Estimands: Bringing clarity and focus to research questions in clinical trials

10.1136/bmjopen-2021-052953 · ExternalCitation · doi-reference

Dynamic Covalent Hydrogels for Wound Healing

10.1146/annurev-chembioeng-082323-093537 · ExternalCitation · doi-reference

Size Matters: Molecular Weight Specificity of Hyaluronan Effects in Cell Biology

10.1155/2015/563818 · ExternalCitation · doi-reference

Revisiting ISO 10993-5 In Vitro Cytotoxicity Standard Tests for Evaluation of Extracellular Matrix-Based Biomaterials

10.1155/ijbm/7395612 · ExternalCitation · doi-reference

A systematic review and meta-analysis assessing the impact of pentoxifylline on the healing and recurrence of venous leg ulcers

10.1177/02683555241309797 · ExternalCitation · doi-reference

An estimate of the economic burden of venous leg ulcers associated with deep venous disease

10.1177/1358863x211028298 · ExternalCitation · doi-reference

Clinical Study of Platelet-Rich Plasma (PRP) for Lower Extremity Venous Ulcers: A Meta-Analysis and Systematic Review

10.1177/15347346211046203 · ExternalCitation · doi-reference

Efficacy and Safety of Pentoxifylline for Venous Leg Ulcers: An Updated Meta-Analysis

10.1177/15347346211050769 · ExternalCitation · doi-reference

Electrically Conductive Hydrogels for Wound Healing

10.1177/21621918251374285 · ExternalCitation · doi-reference

Action of chelators in iron-loaded cardiac cells: Accessibility to intracellular labile iron and functional consequences

10.1182/blood-2006-05-020867 · ExternalCitation · doi-reference

10.1186/s12906-025-05184-3

10.1186/s12906-025-05184-3 · ExternalCitation · doi-reference

More natural more better: Triple natural anti-oxidant puerarin/ferulic acid/polydopamine incorporated hydrogel for wound healing

10.1186/s12951-021-00973-7 · ExternalCitation · doi-reference

Hydrogel-extracellular vesicle engineering delivery system: A promising therapeutic strategy for wound healing

10.1186/s12951-026-04236-1 · ExternalCitation · doi-reference

The effects of the molecular weights of hyaluronic acid on the immune responses

10.1186/s40824-021-00228-4 · ExternalCitation · doi-reference

SANRA-a scale for the quality assessment of narrative review articles

10.1186/s41073-019-0064-8 · ExternalCitation · doi-reference

Inelastic compression increases venous ejection fraction more than elastic bandages in patients with superficial venous reflux

10.1258/phleb.2008.008009 · ExternalCitation · doi-reference

Managing exudate associated with venous leg ulceration

10.12968/bjcn.2012.17.sup6.s6 · ExternalCitation · doi-reference

Managing exudate and maceration in venous leg ulceration within the acute health setting

10.12968/bjon.2017.26.sup20.s18 · ExternalCitation · doi-reference

Comparison of the interface pressure and stiffness of four types of compression systems

10.12968/jowc.2012.21.4.161 · ExternalCitation · doi-reference

Measurement of pH, exudate composition and temperature in wound healing: A systematic review

10.12968/jowc.2017.26.7.381 · ExternalCitation · doi-reference

A simple index to predict healing in venous leg ulcers: A secondary analysis from four randomised controlled trials

10.12968/jowc.2023.32.10.657 · ExternalCitation · doi-reference

10.1371/journal.pmed.1005154

10.1371/journal.pmed.1005154 · ExternalCitation · doi-reference

10.20944/preprints202507.1771.v1

10.20944/preprints202507.1771.v1 · ExternalCitation · doi-reference

Application of Antimicrobial Peptides in Wound Dressings

10.2147/dddt.s543233 · ExternalCitation · doi-reference

Safety of calcium dobesilate in chronic venous disease, diabetic retinopathy and haemorrhoids

10.2165/00002018-200427090-00003 · ExternalCitation · doi-reference

Topically applied heparins for the treatment of vascular disorders: A comprehensive review

10.2165/00044011-200828100-00001 · ExternalCitation · doi-reference

10.3389/fendo.2024.1400462

10.3389/fendo.2024.1400462 · ExternalCitation · doi-reference

10.3389/fmed.2025.1740559

10.3389/fmed.2025.1740559 · ExternalCitation · doi-reference

10.3389/fmedt.2023.1195529

10.3389/fmedt.2023.1195529 · ExternalCitation · doi-reference

10.3389/fphys.2026.1800001

10.3389/fphys.2026.1800001 · ExternalCitation · doi-reference

10.3390/bios16050300

10.3390/bios16050300 · ExternalCitation · doi-reference

10.3390/gels10030188

10.3390/gels10030188 · ExternalCitation · doi-reference

10.3390/gels10080495

10.3390/gels10080495 · ExternalCitation · doi-reference

10.3390/gels12010060

10.3390/gels12010060 · ExternalCitation · doi-reference

10.3390/gels12020182

10.3390/gels12020182 · ExternalCitation · doi-reference

10.3390/gels12050398

10.3390/gels12050398 · ExternalCitation · doi-reference

10.3390/gels4020030

10.3390/gels4020030 · ExternalCitation · doi-reference

10.3390/gels8030167

10.3390/gels8030167 · ExternalCitation · doi-reference

10.3390/gels8090577

10.3390/gels8090577 · ExternalCitation · doi-reference

10.3390/gels9090731

10.3390/gels9090731 · ExternalCitation · doi-reference

10.3390/gels9100802

10.3390/gels9100802 · ExternalCitation · doi-reference

10.3390/healthcare12040500

10.3390/healthcare12040500 · ExternalCitation · doi-reference

10.3390/ijms25169100

10.3390/ijms25169100 · ExternalCitation · doi-reference

10.3390/jcm10010029

10.3390/jcm10010029 · ExternalCitation · doi-reference

10.3390/jcm14061859

10.3390/jcm14061859 · ExternalCitation · doi-reference

10.3390/jcm14217784

10.3390/jcm14217784 · ExternalCitation · doi-reference

10.3390/jfb14110553

10.3390/jfb14110553 · ExternalCitation · doi-reference

10.3390/life16040585

10.3390/life16040585 · ExternalCitation · doi-reference

10.3390/ma18122752

10.3390/ma18122752 · ExternalCitation · doi-reference

10.3390/ph15020171

10.3390/ph15020171 · ExternalCitation · doi-reference

10.3390/pharmaceutics16040524

10.3390/pharmaceutics16040524 · ExternalCitation · doi-reference

10.3390/pharmaceutics16111388

10.3390/pharmaceutics16111388 · ExternalCitation · doi-reference

10.3390/pharmaceutics17020215

10.3390/pharmaceutics17020215 · ExternalCitation · doi-reference

10.3390/polym18010129

10.3390/polym18010129 · ExternalCitation · doi-reference

10.3390/polym9120727

10.3390/polym9120727 · ExternalCitation · doi-reference

Compression therapy for venous leg ulcers

10.4103/2229-5178.137822 · ExternalCitation · doi-reference

Comparing the efficacies of alginate, foam, hydrocolloid, hydrofiber, and hydrogel dressings in the management of diabetic foot ulcers and venous leg ulcers: A systematic review and meta-analysis examining how to dress for success

10.5070/d3228032089 · ExternalCitation · doi-reference

Metal nanoparticle hybrid hydrogels: The state-of-the-art of combining hard and soft materials to promote wound healing

10.7150/thno.91829 · ExternalCitation · doi-reference

Multifunctional hydrogel-based engineered extracellular vesicles delivery for complicated wound healing

10.7150/thno.97317 · ExternalCitation · doi-reference