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References from Single-Cell Transcriptomic Profiling of Peripheral Blood in a Patient with Progressive Thyroid Eye Disease Following Total Thyroidectomy. Local targets link to admitted publications; unresolved targets remain external evidence.
The epidemiologic characteristics and clinical course of ophthalmopathy associated with autoimmune thyroid disease in Olmsted County, Minnesota
1994 · External reference
The 2021 European Group on Graves’ Orbitopathy (EUGOGO) clinical practice guidelines for the management of thyroid eye disease
10.1530/eje-21-0479 · 2021 · External reference
Federal clinical recommendations on diagnostics and treatment of endocrine ophthalmopathy associated with autoimmune thyroid pathology
10.14341/probl201561161-74 · 2015 · External reference
Mycophenolate plus methylprednisolone versus methylprednisolone alone in active, moderate-to-severe Graves’ orbitopathy (MINGO): A randomised, observer-masked, multicentre trial
10.1016/s2213-8587(18)30020-2 · 2018 · External reference
10.3390/life12122084
10.3390/life12122084 · External reference
Teprotumumab: A Review in Thyroid Eye Disease
10.1007/s40265-022-01804-1 · 2022 · External reference
TSH receptor autoantibody levels post-total thyroidectomy in Graves’ ophthalmopathy: A meta-analysis
10.1007/s00423-023-03153-3 · 2023 · External reference
10.1186/s12893-025-03081-7
10.1186/s12893-025-03081-7 · External reference
Graves’ orbitopathy: Imperfect treatments for a rare disease
10.1159/000356042 · 2013 · External reference
Risk factors for development or deterioration of Graves’ ophthalmopathy
10.1089/thy.2010.1634 · 2010 · External reference
Development of Thyroid-Associated Ophthalmopathy in Patients Who Underwent Total Thyroidectomy
10.3349/ymj.2015.56.5.1389 · 2015 · External reference
IL-17 and IL-38 gene polymorphisms in thyroid-associated ophthalmopathy
10.1007/s10792-024-03317-0 · 2024 · External reference
Single-cell RNA sequencing depicts the local cell landscape in thyroid-associated ophthalmopathy
10.1016/j.xcrm.2022.100699 · 2022 · External reference
Transcriptomic profiling of control and thyroid-associated orbitopathy (TAO) orbital fat and TAO orbital fibroblasts undergoing adipogenesis
10.1167/iovs.62.9.24 · 2021 · External reference
Transcriptomic profiling of thyroid eye disease orbital fat demonstrates differences in adipogenicity and IGF-1R pathway
10.1172/jci.insight.182352 · 2024 · External reference
PDGFRα+DPP4+ Fibroblasts-Macrophage Crosstalk Induces Orbital Fibrosis in Treatment-Resistant Thyroid Eye Disease via the GAS6-AXL Pathway
10.1002/advs.202511404 · 2025 · External reference
Bulk and single-cell transcriptomic profiling identifies C1QA as an immune-associated hub gene in graves’ ophthalmopathy
10.1007/s12020-025-04426-1 · 2025 · External reference
Epidemiology of Graves’ orbitopathy (GO) and relationship with thyroid disease
10.1016/j.beem.2011.10.005 · 2012 · External reference
Single-Cell Landscape of Peripheral Blood Mononuclear Cells in Patients with Graves Disease
10.1210/endocr/bqaf038 · 2025 · External reference
Assessment of the levels of interleukin-17 and interleukin-38 in thyroid-associated ophthalmopathy patients
10.1007/s10792-023-02679-1 · 2023 · External reference
Bioassays for TSH Receptor Antibodies: Quo Vadis?
10.1159/000375445 · 2015 · External reference
Interruption of autoimmunity for thyroid eye disease: B-cell and T-cell strategy
10.1038/s41433-018-0315-9 · 2019 · External reference
Intersection of Chemokine and TSH Receptor Pathways in Human Fibrocytes: Emergence of CXCL-12/CXCR4 Cross Talk Potentially Relevant to Thyroid-Associated Ophthalmopathy
10.1210/en.2016-1382 · 2016 · External reference
TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile
10.1073/pnas.1821565116 · 2019 · External reference
10.3389/fimmu.2022.804401
10.3389/fimmu.2022.804401 · External reference
The Efficacy and Safety of Intravenous Tocilizumab to Treat Graves’ Ophthalmopathy: A Systematic Review and Single-arm Meta-analysis
10.1210/clinem/dgae711 · 2025 · External reference
Efficacy and safety of Tocilizumab for thyroid eye disease: A systemic review and Meta-analysis
10.1007/s40618-025-02595-4 · 2025 · External reference
JAK inhibitors (JAKi): Mechanisms of action and perspectives in systemic and autoimmune diseases
10.1016/j.revmed.2024.10.452 · 2025 · External reference
PDGFRα+DPP4+ Fibroblasts-Macrophage Crosstalk Induces Orbital Fibrosis in Treatment-Resistant Thyroid Eye Disease via the GAS6-AXL Pathway
10.1002/advs.202511404 · ExternalCitation · doi-reference
TSH receptor autoantibody levels post-total thyroidectomy in Graves’ ophthalmopathy: A meta-analysis
10.1007/s00423-023-03153-3 · ExternalCitation · doi-reference
Assessment of the levels of interleukin-17 and interleukin-38 in thyroid-associated ophthalmopathy patients
10.1007/s10792-023-02679-1 · ExternalCitation · doi-reference
IL-17 and IL-38 gene polymorphisms in thyroid-associated ophthalmopathy
10.1007/s10792-024-03317-0 · ExternalCitation · doi-reference
Bulk and single-cell transcriptomic profiling identifies C1QA as an immune-associated hub gene in graves’ ophthalmopathy
10.1007/s12020-025-04426-1 · ExternalCitation · doi-reference
Teprotumumab: A Review in Thyroid Eye Disease
10.1007/s40265-022-01804-1 · ExternalCitation · doi-reference
Efficacy and safety of Tocilizumab for thyroid eye disease: A systemic review and Meta-analysis
10.1007/s40618-025-02595-4 · ExternalCitation · doi-reference
Epidemiology of Graves’ orbitopathy (GO) and relationship with thyroid disease
10.1016/j.beem.2011.10.005 · ExternalCitation · doi-reference
JAK inhibitors (JAKi): Mechanisms of action and perspectives in systemic and autoimmune diseases
10.1016/j.revmed.2024.10.452 · ExternalCitation · doi-reference
Single-cell RNA sequencing depicts the local cell landscape in thyroid-associated ophthalmopathy
10.1016/j.xcrm.2022.100699 · ExternalCitation · doi-reference
Mycophenolate plus methylprednisolone versus methylprednisolone alone in active, moderate-to-severe Graves’ orbitopathy (MINGO): A randomised, observer-masked, multicentre trial
10.1016/s2213-8587(18)30020-2 · ExternalCitation · doi-reference
Interruption of autoimmunity for thyroid eye disease: B-cell and T-cell strategy
10.1038/s41433-018-0315-9 · ExternalCitation · doi-reference
TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile
10.1073/pnas.1821565116 · ExternalCitation · doi-reference
Risk factors for development or deterioration of Graves’ ophthalmopathy
10.1089/thy.2010.1634 · ExternalCitation · doi-reference
Graves’ orbitopathy: Imperfect treatments for a rare disease
10.1159/000356042 · ExternalCitation · doi-reference
Bioassays for TSH Receptor Antibodies: Quo Vadis?
10.1159/000375445 · ExternalCitation · doi-reference
Transcriptomic profiling of control and thyroid-associated orbitopathy (TAO) orbital fat and TAO orbital fibroblasts undergoing adipogenesis
10.1167/iovs.62.9.24 · ExternalCitation · doi-reference
Transcriptomic profiling of thyroid eye disease orbital fat demonstrates differences in adipogenicity and IGF-1R pathway
10.1172/jci.insight.182352 · ExternalCitation · doi-reference
10.1186/s12893-025-03081-7
10.1186/s12893-025-03081-7 · ExternalCitation · doi-reference
The Efficacy and Safety of Intravenous Tocilizumab to Treat Graves’ Ophthalmopathy: A Systematic Review and Single-arm Meta-analysis
10.1210/clinem/dgae711 · ExternalCitation · doi-reference
Intersection of Chemokine and TSH Receptor Pathways in Human Fibrocytes: Emergence of CXCL-12/CXCR4 Cross Talk Potentially Relevant to Thyroid-Associated Ophthalmopathy
10.1210/en.2016-1382 · ExternalCitation · doi-reference
Single-Cell Landscape of Peripheral Blood Mononuclear Cells in Patients with Graves Disease
10.1210/endocr/bqaf038 · ExternalCitation · doi-reference
Federal clinical recommendations on diagnostics and treatment of endocrine ophthalmopathy associated with autoimmune thyroid pathology
10.14341/probl201561161-74 · ExternalCitation · doi-reference
The 2021 European Group on Graves’ Orbitopathy (EUGOGO) clinical practice guidelines for the management of thyroid eye disease
10.1530/eje-21-0479 · ExternalCitation · doi-reference
Development of Thyroid-Associated Ophthalmopathy in Patients Who Underwent Total Thyroidectomy
10.3349/ymj.2015.56.5.1389 · ExternalCitation · doi-reference
10.3389/fimmu.2022.804401
10.3389/fimmu.2022.804401 · ExternalCitation · doi-reference
10.3390/life12122084
10.3390/life12122084 · ExternalCitation · doi-reference
