Research graph
References from Multidrug-Resistant Bloodstream Infections Before and After COVID-19: A Temporal Assessment of Outcomes and Resistance Across Two Eras in a Non-COVID Intensive Care Unit—The MATURATE ICU Study. Local targets link to admitted publications; unresolved targets remain external evidence.
Global burden of bacterial antimicrobial resistance 1990–2021: A systematic analysis with forecasts to 2050
10.1016/s0140-6736(24)01867-1 · 2024 · External reference
10.3390/antibiotics14121179
10.3390/antibiotics14121179 · External reference
Antimicrobial resistance before and after the COVID-19 pandemic in Northern Brazil
10.1017/ash.2026.10341 · 2026 · External reference
10.3390/microorganisms11051299
10.3390/microorganisms11051299 · External reference
Bloodstream infections in the era of the COVID-19 pandemic: Changing epidemiology of antimicrobial resistance in the intensive care unit
10.1016/j.jointm.2023.12.004 · 2024 · External reference
10.20944/preprints202508.0812.v1
10.20944/preprints202508.0812.v1 · External reference
10.3389/fpubh.2025.1607801
10.3389/fpubh.2025.1607801 · External reference
10.3390/antibiotics14090916
10.3390/antibiotics14090916 · External reference
Unresolved reference
External reference
10.20944/preprints202304.1195.v1
10.20944/preprints202304.1195.v1 · External reference
Healthcare-associated infections and antimicrobial use in acute care hospitals in Greece, 2022; results of the third point prevalence survey
10.1186/s13756-024-01367-8 · 2024 · External reference
Candidemia Epidemiology and Antifungal Resistance in Critically-ill Patients During and After COVID-19 Pandemic: Comparison Between Two Hospitals in Greece and Türkiye
10.1007/s11046-026-01086-1 · 2026 · External reference
10.3390/antibiotics11091258
10.3390/antibiotics11091258 · External reference
10.3390/antibiotics14090898
10.3390/antibiotics14090898 · External reference
10.20944/preprints202604.0076.v1
10.20944/preprints202604.0076.v1 · External reference
Differences between COVID-19 and non-COVID-19 patients’ bloodstream infections: A single-center retrospective study
10.3855/jidc.20929 · 2025 · External reference
10.3390/antibiotics12071105
10.3390/antibiotics12071105 · External reference
Bloodstream infections in critically ill patients with COVID-19
10.1111/eci.13319 · 2020 · External reference
10.3390/jcm12062252
10.3390/jcm12062252 · External reference
The impact of the COVID-19 pandemic on hospital-acquired infections at a comprehensive cancer center
10.1016/j.ajic.2023.08.019 · 2023 · External reference
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2026
2026 · External reference
10.3390/biomedicines14020479
10.3390/biomedicines14020479 · External reference
Performance of molecular tests for diagnosis of bloodstream infections in the clinical setting: A systematic literature review and meta-analysis
10.1016/j.cmi.2024.12.007 · 2025 · External reference
10.1093/cid/ciae403
10.1093/cid/ciae403 · External reference
European Society of Clinical Microbiology and Infectious Diseases (ESCMID) guidelines for the treatment of infections caused by multidrug-resistant Gram-negative bacilli (endorsed by European society of intensive care medicine)
10.1016/j.cmi.2021.11.025 · 2022 · External reference
10.1093/cid/ciag481
10.1093/cid/ciag481 · External reference
Extracorporeal organ support for critically ill patients: Overcoming the past, achieving the maximum at present, and redefining the future
10.5492/wjccm.v13.i2.92458 · 2024 · External reference
An Update on Management of Adult Patients with Acute Respiratory Distress Syndrome: An Official American Thoracic Society Clinical Practice Guideline
10.1164/rccm.202311-2011st · 2024 · External reference
10.3390/jpm13060891
10.3390/jpm13060891 · External reference
Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: An international expert proposal for interim standard definitions for acquired resistance
10.1111/j.1469-0691.2011.03570.x · 2012 · External reference
Multidrug-Resistant Candida: Epidemiology, Molecular Mechanisms, and Treatment
10.1093/infdis/jix131 · 2017 · External reference
Unresolved reference
External reference
A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation
10.1016/0021-9681(87)90171-8 · 1987 · External reference
The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine
10.1007/bf01709751 · 1996 · External reference
Acute physiology and chronic health evaluation (APACHE II) and Medicare reimbursement
1984 · External reference
Resilience of the Pitt Bacteremia Score: 3 Decades and Counting
10.1093/cid/ciz535 · 2020 · External reference
Unresolved reference
External reference
Unresolved reference
External reference
10.3389/fphar.2025.1727662
10.3389/fphar.2025.1727662 · External reference
10.3389/fcvm.2022.967614
10.3389/fcvm.2022.967614 · External reference
Level of Hypoalbuminemia as a Prognostic Factor in Patients admitted to a Tertiary Care Intensive Coronary Care Unit
10.26502/fccm.92920296 · 2022 · External reference
10.3389/fphys.2023.1064699
10.3389/fphys.2023.1064699 · External reference
Strain on Scarce Intensive Care Beds Drives Reduced Patient Volumes, Patient Selection, and Worse Outcome: A National Cohort Study
10.1097/ccm.0000000000006156 · 2024 · External reference
COVID-19 pandemic in ICU. Limited resources for many patients: Approaches and criteria for triaging
10.23736/s0375-9393.21.15736-0 · 2021 · External reference
Prioritisation of ICU treatments for critically ill patients in a COVID-19 pandemic with scarce resources
2020 · External reference
The impact of COVID-19 pandemic on the indications of non-COVID-19 obstetric and gynecological admissions to the intensive care unit (ICU) and its overall consequences
10.1038/s41598-023-46755-z · 2023 · External reference
10.1101/2022.02.28.22271604
10.1101/2022.02.28.22271604 · External reference
Use of Life Support and Outcomes Among Patients Admitted to Intensive Care Units
10.1001/jama.2025.2163 · 2025 · External reference
The Microbiology of Bloodstream Infection: 20-Year Trends from the SENTRY Antimicrobial Surveillance Program
10.1128/aac.00355-19 · 2019 · External reference
Antimicrobial resistance burden pre and post-COVID-19 pandemic with mapping the multidrug resistance in Egypt: A comparative cross-sectional study
10.1038/s41598-024-56254-4 · 2024 · External reference
Eight-year trends in the relative isolation frequency and antimicrobial susceptibility among bloodstream isolates from Greek hospitals: Data from the Greek Electronic System for the Surveillance of Antimicrobial Resistance-WHONET-Greece, 2010 to 2017
10.2807/1560-7917.es.2020.25.34.1900516 · 2020 · External reference
10.3390/pathogens15050467
10.3390/pathogens15050467 · External reference
10.3390/antibiotics14030239
10.3390/antibiotics14030239 · External reference
International Study of the Prevalence and Outcomes of Infection in Intensive Care Units
10.1001/jama.2009.1754 · 2009 · External reference
Epidemiology and Outcomes of Bloodstream Infections in Patients in a Burns Intensive Care Unit: An 8-Year Retrospective Study
10.1093/ofid/ofaf151 · 2025 · External reference
Staphylococcus epidermidis—the ‘accidental’ pathogen
10.1038/nrmicro2182 · 2009 · External reference
Influence of insertion site on central venous catheter colonization and bloodstream infection rates
10.1007/s00134-008-1046-3 · 2008 · External reference
Central venous catheter-related infection: Does insertion site still matter? A French multicentric cohort study
10.1007/s00134-024-07615-0 · 2024 · External reference
10.1186/s12879-026-12837-2
10.1186/s12879-026-12837-2 · External reference
Unresolved reference
External reference
10.3390/microorganisms13010183
10.3390/microorganisms13010183 · External reference
Unresolved reference
External reference
Unresolved reference
External reference
10.3390/pathogens12081044
10.3390/pathogens12081044 · External reference
The impact of multidrug resistance in healthcare-associated and nosocomial Gram-negative bacteraemia on mortality and length of stay: Cohort study
10.1111/j.1469-0691.2011.03606.x · 2012 · External reference
Predictors of mortality in bloodstream infections caused by multidrug-resistant gram-negative bacteria: 4 years of collection
10.1016/j.ajic.2016.08.008 · 2017 · External reference
The impact of organ dysfunctions on mortality in patients with severe sepsis: A multicenter prospective observational study
10.1016/j.jcrc.2018.03.011 · 2018 · External reference
Bloodstream infections: Mechanisms of pathogenesis and opportunities for intervention
10.1038/s41579-024-01105-2 · 2025 · External reference
Epidemiology and Prognostic Determinants of Bloodstream Infections in Surgical Intensive Care
10.1001/archsurg.137.12.1353 · 2002 · External reference
Outcomes in severe sepsis and patients with septic shock: Pathogen species and infection sites are not associated with mortality
10.1097/ccm.0b013e31821b827c · 2011 · External reference
10.1007/s10096-026-05577-3
10.1007/s10096-026-05577-3 · External reference
10.1371/journal.pone.0332807
10.1371/journal.pone.0332807 · External reference
Predictors of mortality in sepsis patients with Acinetobacter baumannii and Klebsiella pneumoniae bacteremia
10.1016/j.cegh.2025.102090 · 2025 · External reference
Health systems resilience in managing the COVID-19 pandemic: Lessons from 28 countries
10.1038/s41591-021-01381-y · 2021 · External reference
10.3389/fpubh.2022.1073809
10.3389/fpubh.2022.1073809 · External reference
Why Resilience in Health Care Systems is More than Coping with Disasters: Implications for Health Care Policy
10.1007/s41471-022-00132-0 · 2022 · External reference
10.3390/healthcare14050569
10.3390/healthcare14050569 · External reference
Epidemiology and Prognostic Determinants of Bloodstream Infections in Surgical Intensive Care
10.1001/archsurg.137.12.1353 · ExternalCitation · doi-reference
International Study of the Prevalence and Outcomes of Infection in Intensive Care Units
10.1001/jama.2009.1754 · ExternalCitation · doi-reference
Use of Life Support and Outcomes Among Patients Admitted to Intensive Care Units
10.1001/jama.2025.2163 · ExternalCitation · doi-reference
The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine
10.1007/bf01709751 · ExternalCitation · doi-reference
Influence of insertion site on central venous catheter colonization and bloodstream infection rates
10.1007/s00134-008-1046-3 · ExternalCitation · doi-reference
Central venous catheter-related infection: Does insertion site still matter? A French multicentric cohort study
10.1007/s00134-024-07615-0 · ExternalCitation · doi-reference
10.1007/s10096-026-05577-3
10.1007/s10096-026-05577-3 · ExternalCitation · doi-reference
Candidemia Epidemiology and Antifungal Resistance in Critically-ill Patients During and After COVID-19 Pandemic: Comparison Between Two Hospitals in Greece and Türkiye
10.1007/s11046-026-01086-1 · ExternalCitation · doi-reference
Why Resilience in Health Care Systems is More than Coping with Disasters: Implications for Health Care Policy
10.1007/s41471-022-00132-0 · ExternalCitation · doi-reference
A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation
10.1016/0021-9681(87)90171-8 · ExternalCitation · doi-reference
Predictors of mortality in bloodstream infections caused by multidrug-resistant gram-negative bacteria: 4 years of collection
10.1016/j.ajic.2016.08.008 · ExternalCitation · doi-reference
The impact of the COVID-19 pandemic on hospital-acquired infections at a comprehensive cancer center
10.1016/j.ajic.2023.08.019 · ExternalCitation · doi-reference
Predictors of mortality in sepsis patients with Acinetobacter baumannii and Klebsiella pneumoniae bacteremia
10.1016/j.cegh.2025.102090 · ExternalCitation · doi-reference
European Society of Clinical Microbiology and Infectious Diseases (ESCMID) guidelines for the treatment of infections caused by multidrug-resistant Gram-negative bacilli (endorsed by European society of intensive care medicine)
10.1016/j.cmi.2021.11.025 · ExternalCitation · doi-reference
Performance of molecular tests for diagnosis of bloodstream infections in the clinical setting: A systematic literature review and meta-analysis
10.1016/j.cmi.2024.12.007 · ExternalCitation · doi-reference
The impact of organ dysfunctions on mortality in patients with severe sepsis: A multicenter prospective observational study
10.1016/j.jcrc.2018.03.011 · ExternalCitation · doi-reference
Bloodstream infections in the era of the COVID-19 pandemic: Changing epidemiology of antimicrobial resistance in the intensive care unit
10.1016/j.jointm.2023.12.004 · ExternalCitation · doi-reference
Global burden of bacterial antimicrobial resistance 1990–2021: A systematic analysis with forecasts to 2050
10.1016/s0140-6736(24)01867-1 · ExternalCitation · doi-reference
Antimicrobial resistance before and after the COVID-19 pandemic in Northern Brazil
10.1017/ash.2026.10341 · ExternalCitation · doi-reference
Staphylococcus epidermidis—the ‘accidental’ pathogen
10.1038/nrmicro2182 · ExternalCitation · doi-reference
Bloodstream infections: Mechanisms of pathogenesis and opportunities for intervention
10.1038/s41579-024-01105-2 · ExternalCitation · doi-reference
Health systems resilience in managing the COVID-19 pandemic: Lessons from 28 countries
10.1038/s41591-021-01381-y · ExternalCitation · doi-reference
The impact of COVID-19 pandemic on the indications of non-COVID-19 obstetric and gynecological admissions to the intensive care unit (ICU) and its overall consequences
10.1038/s41598-023-46755-z · ExternalCitation · doi-reference
Antimicrobial resistance burden pre and post-COVID-19 pandemic with mapping the multidrug resistance in Egypt: A comparative cross-sectional study
10.1038/s41598-024-56254-4 · ExternalCitation · doi-reference
10.1093/cid/ciae403
10.1093/cid/ciae403 · ExternalCitation · doi-reference
10.1093/cid/ciag481
10.1093/cid/ciag481 · ExternalCitation · doi-reference
Resilience of the Pitt Bacteremia Score: 3 Decades and Counting
10.1093/cid/ciz535 · ExternalCitation · doi-reference
Multidrug-Resistant Candida: Epidemiology, Molecular Mechanisms, and Treatment
10.1093/infdis/jix131 · ExternalCitation · doi-reference
Epidemiology and Outcomes of Bloodstream Infections in Patients in a Burns Intensive Care Unit: An 8-Year Retrospective Study
10.1093/ofid/ofaf151 · ExternalCitation · doi-reference
Strain on Scarce Intensive Care Beds Drives Reduced Patient Volumes, Patient Selection, and Worse Outcome: A National Cohort Study
10.1097/ccm.0000000000006156 · ExternalCitation · doi-reference
Outcomes in severe sepsis and patients with septic shock: Pathogen species and infection sites are not associated with mortality
10.1097/ccm.0b013e31821b827c · ExternalCitation · doi-reference
10.1101/2022.02.28.22271604
10.1101/2022.02.28.22271604 · ExternalCitation · doi-reference
Bloodstream infections in critically ill patients with COVID-19
10.1111/eci.13319 · ExternalCitation · doi-reference
Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: An international expert proposal for interim standard definitions for acquired resistance
10.1111/j.1469-0691.2011.03570.x · ExternalCitation · doi-reference
The impact of multidrug resistance in healthcare-associated and nosocomial Gram-negative bacteraemia on mortality and length of stay: Cohort study
10.1111/j.1469-0691.2011.03606.x · ExternalCitation · doi-reference
The Microbiology of Bloodstream Infection: 20-Year Trends from the SENTRY Antimicrobial Surveillance Program
10.1128/aac.00355-19 · ExternalCitation · doi-reference
An Update on Management of Adult Patients with Acute Respiratory Distress Syndrome: An Official American Thoracic Society Clinical Practice Guideline
10.1164/rccm.202311-2011st · ExternalCitation · doi-reference
10.1186/s12879-026-12837-2
10.1186/s12879-026-12837-2 · ExternalCitation · doi-reference
Healthcare-associated infections and antimicrobial use in acute care hospitals in Greece, 2022; results of the third point prevalence survey
10.1186/s13756-024-01367-8 · ExternalCitation · doi-reference
10.1371/journal.pone.0332807
10.1371/journal.pone.0332807 · ExternalCitation · doi-reference
10.20944/preprints202304.1195.v1
10.20944/preprints202304.1195.v1 · ExternalCitation · doi-reference
10.20944/preprints202508.0812.v1
10.20944/preprints202508.0812.v1 · ExternalCitation · doi-reference
10.20944/preprints202604.0076.v1
10.20944/preprints202604.0076.v1 · ExternalCitation · doi-reference
COVID-19 pandemic in ICU. Limited resources for many patients: Approaches and criteria for triaging
10.23736/s0375-9393.21.15736-0 · ExternalCitation · doi-reference
Level of Hypoalbuminemia as a Prognostic Factor in Patients admitted to a Tertiary Care Intensive Coronary Care Unit
10.26502/fccm.92920296 · ExternalCitation · doi-reference
Eight-year trends in the relative isolation frequency and antimicrobial susceptibility among bloodstream isolates from Greek hospitals: Data from the Greek Electronic System for the Surveillance of Antimicrobial Resistance-WHONET-Greece, 2010 to 2017
10.2807/1560-7917.es.2020.25.34.1900516 · ExternalCitation · doi-reference
10.3389/fcvm.2022.967614
10.3389/fcvm.2022.967614 · ExternalCitation · doi-reference
10.3389/fphar.2025.1727662
10.3389/fphar.2025.1727662 · ExternalCitation · doi-reference
10.3389/fphys.2023.1064699
10.3389/fphys.2023.1064699 · ExternalCitation · doi-reference
10.3389/fpubh.2022.1073809
10.3389/fpubh.2022.1073809 · ExternalCitation · doi-reference
10.3389/fpubh.2025.1607801
10.3389/fpubh.2025.1607801 · ExternalCitation · doi-reference
10.3390/antibiotics11091258
10.3390/antibiotics11091258 · ExternalCitation · doi-reference
10.3390/antibiotics12071105
10.3390/antibiotics12071105 · ExternalCitation · doi-reference
10.3390/antibiotics14030239
10.3390/antibiotics14030239 · ExternalCitation · doi-reference
10.3390/antibiotics14090898
10.3390/antibiotics14090898 · ExternalCitation · doi-reference
10.3390/antibiotics14090916
10.3390/antibiotics14090916 · ExternalCitation · doi-reference
10.3390/antibiotics14121179
10.3390/antibiotics14121179 · ExternalCitation · doi-reference
10.3390/biomedicines14020479
10.3390/biomedicines14020479 · ExternalCitation · doi-reference
10.3390/healthcare14050569
10.3390/healthcare14050569 · ExternalCitation · doi-reference
10.3390/jcm12062252
10.3390/jcm12062252 · ExternalCitation · doi-reference
10.3390/jpm13060891
10.3390/jpm13060891 · ExternalCitation · doi-reference
10.3390/microorganisms11051299
10.3390/microorganisms11051299 · ExternalCitation · doi-reference
10.3390/microorganisms13010183
10.3390/microorganisms13010183 · ExternalCitation · doi-reference
10.3390/pathogens12081044
10.3390/pathogens12081044 · ExternalCitation · doi-reference
10.3390/pathogens15050467
10.3390/pathogens15050467 · ExternalCitation · doi-reference
Differences between COVID-19 and non-COVID-19 patients’ bloodstream infections: A single-center retrospective study
10.3855/jidc.20929 · ExternalCitation · doi-reference
Extracorporeal organ support for critically ill patients: Overcoming the past, achieving the maximum at present, and redefining the future
10.5492/wjccm.v13.i2.92458 · ExternalCitation · doi-reference
